Pneumolysin potentiates production of prostaglandin E2 and leukotriene B4 by human neutrophils

Infection and Immunity

Volumn 69, Issue 5, 2001, Pages 3494-3496

  Cockeran, R ^a   Steel, H C ^a   Mitchell, T J ^a   Feldman, C ^a   Anderson, R ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; LEUKOTRIENE B4; PHOSPHOLIPASE A2; PNEUMOLYSIN; PROSTAGLANDIN E2;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; PRIORITY JOURNAL; STREPTOCOCCUS INFECTION;

ADULT; BACTERIAL PROTEINS; DINOPROSTONE; HUMANS; LEUKOTRIENE B4; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PNEUMOCOCCAL INFECTIONS; STREPTOLYSINS;

EID: 0035059186     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.5.3494-3496.2001     Document Type: Article

References (10)

1. Autooxidation as a basis for altered function by polymorphonuclear leukocytes
2. Pneumolysin, a protein toxin of Streptococcus pneumoniae, induces nitric oxide production from macrophages
3. Asthma and leukotrienes: Antileukotrienes as novel antiasthmatic drugs
4. Proinflammatory interactions of pneumolysin with human neutrophils
5. Immunomodulation by neutrophil myeloperoxidase and hydrogen peroxide: Differential susceptibility of human lymphocyte functions
6. Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin 1 β by human mononuclear phagocytes
7. Host cellular immune response to pneumococcal lung infection in mice
8. Agents that elevate CAMP inhibit neutrophil apoptosis
9. Pneumolysin activates phospholipase A in pulmonary artery endothelial cells
10. Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity