A conserved tryptophan in pneumolysin is a determinant of the characteristics of channels formed by pneumolysin in cells and planar lipid bilayers

Biochemical Journal

Volumn 329, Issue 3, 1998, Pages 571-577

  Korchev, Yuri E ^a   Bashford, C Lindsay ^a   Pederzolli, Cecilia ^a,c   Pasternak, Charles A ^a   Morgan, Peter J ^b   Andrew, Peter W ^b   Mitchell, Timothy J ^b,d  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c CNR   (Italy)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; DIVALENT CATION; ION CHANNEL; MUTANT PROTEIN; PNEUMOLYSIN; POLYSACCHARIDE; TOXIN; TRYPTOPHAN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ELECTRON MICROSCOPY; HEMOLYSIS; LIPID BILAYER; MEMBRANE CHANNEL; MEMBRANE CONDUCTANCE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TOXIN STRUCTURE;

ANIMALIA;

EID: 0032007852     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3290571     Document Type: Article

References (38)

1. Paton, J. C., Andrew, P. W., Boulnois, G. J. and Mitchell, T. J. (1993) Annu. Rev. Microbiol. 47, 89-115
2. Boulnois, G. J., Paton, J. C., Mitchell, T. J. and Andrew, P. W. (1991) Mol. Microbiol. 5, 2611-2616
3. Alouf, J. E. and Geoffroy, C. (1991) in Source of Bacterial Protein Toxins (Alouf, J. E. and Freer, J. H., eds.), pp. 147-186, Academic Press, London
4. Mitchell, T. J., Andrew, P. W., Saunders, F. K., Smith, A. N. and Boulnois, G. J. (1991) Mol. Microbiol. 5, 1883-1888
5. Andrew, P. W., Boulnois, G. J., Mitchell, T. J., Lee, C. J., Paton, J. C., Poolman, J. T. and Peeters, C. C. A. M. (1994) Zentbl. Bakt. S24, 453-466
6. Saunders, F. K., Mitchell, T. J., Walker, J. A., Andrew, P. W. and Boulnois, G. J. (1989) Infect Immun. 57, 2547-2452
7. Kunkel, T. A., Roberts, J. D. and Zabour, R. A. (1987) Methods. Enzymol. 154, 367-382
8. Sanger, F., Nicklen, S. and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463
9. Mitchell, T. J., Walker, J. A., Saunders, F. K., Andrew, P. W. and Boulnois, G. J. (1989) Biochim. Biophys. Acta 1007, 67-72
10. Laemmli, U. K. (1970) Nature (London) 227, 680-685
11. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
12. Johnson, M. K., Geoffroy, C. and Alouf, J. E. (1980) Infect Immun. 27, 97-101
13. Green, H., Barrow, P. and Goldberg, B. (1959) J. Exp. Med. 110, 699-713
14. Sears, D. A., Weed, R. I. and Swisher, S. N. (1964) J. Clin. Invest. 43, 975-985
15. Towbin, H., Staehelin, T. and Gordon, J. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354
16. Morgan, P. J., Hyman, S. C., Rowe, A. J., Mitchell, T. J., Andrew, P. W. and Saibil, H. R. (1995) FEBS Lett. 371, 77-80
17. Morgan, P. J., Varley, P. G., Hyman, S., Byron, O., Andrew, P. W., Mitchell, T. J. and Rowe, A. J. (1994) J. Biol. Chem. 269, 25315-25320
18. Bashford, C. L., Alder, G. M., Graham, J. M., Menestrina, G. and Pasternak, C. A. (1988) J. Membrane Biol. 103, 79-94
19. Impraim, C. C., Foster, K. A., Wicklem, K. J. and Pasternak, C. A. (1980) Biochem. J. 186, 847-860
20. Bashford, C. L., Alder, G. M., Micklem, K. J. and Pasternak, C. A. (1983) Biosci. Rep. 3, 631-642
21. Bashford, C. L. and Pasternak, C. A. (1984) J. Membr. Biol. 79, 275-284
22. Bashford, C. L. and Pasternak, C. A. (1985) Biochim. Biophys. Acta 817, 174-180
23. Korchev, Y. E., Bashford, C. L. and Pasternak, C. A. (1992) J. Membr. Biol. 127, 195-203
24. Forda, S. R., Gillies, G., Kelly, J. S., Micklem, K. J. and Pasternak, C. A. (1982) Neurosci. Lett 29, 237-242
25. Micklem, K. J., Nyaruwe, A. and Pasternak, C. A. (1985) Mol. Biochem. 66, 163-173
26. Bashford, C. L. Menestrina, G., Henkart, P. A. and Pasternak, C. A. (1988) Immunology 141, 3965-3974
27. Korchev, Y. E., Alder, G. M., Bakhramov, A., Bashford, C. L., Joomun, B. S., Sviderskaya, E. V., Usherwood, P. N. R. and Pasternak, C. A. (1995) J. Membr. Biol. 143, 143-151
28. Blumenthal, R. and Habig, W. H. (1984) J. Bacteriol. 157, 321-323
29. Bhakdi, S., Muhly, M. and Fussle, R. (1984) Infect Immun. 46, 318-323
30. Michel, E., Reich, K. A., Favier, R., Berche, P. and Cossart, P. (1990) Mol. Microbiol. 4, 2167-2178
31. Pinkey, M., Beachey, E. and Kehoe, M. (1989) Infect. Immun. 57, 2553-2558
32. Boulnois, G. J., Mitchell, T. J., Saunders, F. K., Owen, R. H. G., Canvin, J. R., Wilson, R., Feldman, C., Bashford, L., Pasternack, C. and Andrew, P. W. (1990) in Genetics and Molecular Biology of Streptococci, Lactococci and Enterococci, (Dunny, G. M., Cleary, P. P. and McKay, L. L., eds.), pp. 83-67, American Society for Microbiology/Herndon, VA, U.S.A.
33. deKruijff, B. (1990) Biosci. Rep. 10, 127-130
34. Bashford, C. L., Alder, G. M., Menestrina, G., Micklem, K. J., Murphy, J. J. and Pasternak, C. A. (1986) J. Biol. Chem. 261, 9300-9308
35. Thelestam, M. and Mollby, R. (1980) Infect Immun. 29, 863-872
36. Menestrina, G., Bashford, C. L. and Pasternak, C. A. (1990) Toxicon 28, 477-491
37. Zimmerberg, J. and Parsegian, V. A. (1986) Nature (London) 323, 36-42
38. Vodyanoy, I., Bezrukov, S. M. and Parsegian, V. A. (1993) Biophys. J. 65, 2097-2105