Pneumolysin causes neuronal cell death through mitochondrial damage

Infection and Immunity

Volumn 75, Issue 9, 2007, Pages 4245-4254

  Braun, Johann S ^a,b   Hoffmann, Olaf ^a   Schickhaus, Miriam ^a   Freyer, Dorette ^a   Dagand, Emilie ^a   Bermpohl, Daniela ^a   Mitchell, Tim J ^c   Bechmann, Ingo ^a   Weber, Joerg R ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; BACTERIAL TOXIN; CASPASE 3; CASPASE 8; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA CONVERTING ENZYME; PNEUMOLYSIN; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; APOPTOSIS; ARTICLE; BACTERIAL MENINGITIS; BRAIN MITOCHONDRION; CHANNEL GATING; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME REPRESSION; FETUS; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; RAT; STREPTOCOCCUS PNEUMONIAE; UPREGULATION;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; CALCIUM; CELL DEATH; CELLS, CULTURED; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; NEURONS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS; UP-REGULATION;

EID: 34548485364     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00031-07     Document Type: Article

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