A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation

Stem Cells

Volumn 26, Issue 4, 2008, Pages 850-863

  Yang, Chunbo ^a   Przyborski, Stefan ^a,b   Cooke, Michael J ^a,b   Zhang, Xin ^a   Stewart, Rebecca ^a   Anyfantis, George ^a   Atkinson, Stuart P ^a   Saretzki, Gabriele ^a   Armstrong, Lyle ^a   Lako, Majlinda ^a,c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b DURHAM UNIVERSITY   (United Kingdom)

^c INSTITUTE OF HUMAN GENETICS   (United Kingdom)

Author keywords

Cell cycle; Human embryonic stem cells; In vitro differentiation; Telomerase; Telomerase reverse transcriptase; Telomerase RNA component

Indexed keywords

CELL CYCLE PROTEIN 6; CYCLIN D1; DNA; PEROXIDE; RETINOBLASTOMA PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; TELOMERASE; TERT PROTEIN, HUMAN;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; COLONY FORMING UNIT; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; GENE; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PLURIPOTENT STEM CELL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TERT GENE; UPREGULATION; BIOSYNTHESIS; CELL CULTURE; CELL LINE; COMPARATIVE STUDY; CYTOLOGY; GENETICS; METHODOLOGY; MOLECULAR CLONING; PHYSIOLOGY;

CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; CLONING, MOLECULAR; EMBRYONIC STEM CELLS; HUMANS; TELOMERASE;

EID: 49249111098     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0677     Document Type: Article

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