Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells

Stem Cells

Volumn 26, Issue 2, 2008, Pages 455-464

  Saretzki, Gabriele ^a,b   Walter, Theresia ^c   Atkinson, Stuart ^c   Passos, João F ^b   Bareth, Bettina ^b   Keith, W Nicol ^c   Stewart, Rebecca ^c   Hoare, Stacey ^d   Stojkovic, Miodrag ^c   Armstrong, Lyle ^c   Von Zglinicki, Thomas ^b   Lako, Majlinda ^c  

^a INSTITUTE OF HUMAN GENETICS   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Antioxidant; Disposable soma; DNA damage; Mitochondria; Reactive oxygen species; Stem cells; Telomerase; Telomere

Indexed keywords

HISTONE H3; HISTONE H4; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CELL STRESS; DEACETYLATION; DEFENSE MECHANISM; DNA REPAIR; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; GERM CELL; HUMAN; HUMAN CELL; HYPOTHESIS; MOLECULAR EVOLUTION; OXIDATIVE STRESS; SOMATIC CELL; TELOMERE;

ANTIOXIDANTS; CELL DIFFERENTIATION; CELL LINE; DNA DAMAGE; DNA REPAIR; DOWN-REGULATION; EMBRYONIC STEM CELLS; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TELOMERE;

EID: 40949088547     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0628     Document Type: Article

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