High-content siRNA screening for target identification and validation

Expert Opinion on Drug Discovery

Volumn 3, Issue 5, 2008, Pages 551-564

  Krausz, Eberhard ^a   Korn, Kerstin ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

Automated microscopy; Functional genomics; High content; High throughput; Image analysis; Multi parametric assay; RNA interference; RNAi; Screening; Short interfering RNA; siRNA; Systems biology; Target identification; Target validation

Indexed keywords

PHOSPHOTRANSFERASE; SMALL INTERFERING RNA;

BACTERIAL GROWTH; CELL ASSAY; CELL CYCLE REGULATION; CELL MIGRATION; CELL SCREENING; DNA CONTENT; DNA DETERMINATION; ENDOCYTOSIS; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE SILENCING; GENE TARGETING; HIGH CONTENT SCREENING; HIGH THROUGHPUT SCREENING; IMAGE ANALYSIS; INTRACELLULAR TRANSPORT; IRON TRANSPORT; MAMMAL CELL; MICROSCOPY; MOLECULAR LIBRARY; NEUROBIOLOGY; NONHUMAN; ONCOLOGY; PRIORITY JOURNAL; REPRODUCIBILITY; REVIEW; RNA INTERFERENCE; VIRUS INFECTION;

EID: 44649106998     PISSN: 17460441     EISSN: None     Source Type: Journal    
DOI: 10.1517/17460441.3.5.551     Document Type: Review

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