Identification of gap junction blockers using automated fluorescence microscopy imaging

Journal of Biomolecular Screening

Volumn 8, Issue 5, 2003, Pages 489-499

  Li, Zhuyin ^a,b   Yan, Yongping ^a   Powers, Elaine A ^b   Ying, Xiaoyou ^b   Janjua, Khurram ^a   Garyantes, Tina ^a   Baron, Bruce ^b  

^a Discovery Technology   (Finland)

^b SANOFI   (France)

Author keywords

Automated fluorescence microscopy imaging; Bioimaging; Fluorescence microscopy based imaging; Gap junction; High content screening; High throughput screening

Indexed keywords

CALCEIN; FLUORESCENT DYE; GAP JUNCTION BLOCKER; GAP JUNCTION PROTEIN; UNCLASSIFIED DRUG; FLUORESCEIN DERIVATIVE; MECLOFENAMIC ACID;

ANIMAL CELL; ARTICLE; AUTOMATION; CELL DENSITY; CELL SYNCHRONIZATION; ELECTRIC ACTIVITY; FLUORESCENCE MICROSCOPY; GAP JUNCTION; GENE TARGETING; HIGH THROUGHPUT SCREENING; IMAGE PROCESSING; IMAGING SYSTEM; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; TECHNOLOGY; ANIMAL; CELL COMMUNICATION; CELL CULTURE; CELL DIVISION; CELL JUNCTION; CENTRAL NERVOUS SYSTEM TUMOR; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; GLIOMA; LABORATORY DIAGNOSIS; METABOLISM; METHODOLOGY; PATHOLOGY; PHYSIOLOGY; SENSITIVITY AND SPECIFICITY; TIME;

ANIMALS; AUTOMATION; CELL COMMUNICATION; CELL DIVISION; CENTRAL NERVOUS SYSTEM NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FALSE POSITIVE REACTIONS; FLUORESCEINS; FLUORESCENT DYES; GAP JUNCTIONS; GLIOMA; IMAGE PROCESSING, COMPUTER-ASSISTED; MECLOFENAMIC ACID; MICROSCOPY, FLUORESCENCE; RATS; SENSITIVITY AND SPECIFICITY; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 1542598052     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057103257309     Document Type: Article

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