-
1
-
-
0034708480
-
The genome sequence of Drosophila melanogaster
-
Adams, M.D. et al. The genome sequence of Drosophila melanogaster. Science 287, 2185-2195 (2000).
-
(2000)
Science
, vol.287
, pp. 2185-2195
-
-
Adams, M.D.1
-
2
-
-
0037062951
-
RNA interference
-
Hannon, G.J. RNA interference. Nature 418, 244-251 (2002).
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
4
-
-
14644393684
-
Perspective: Machines for RNAi
-
Tomari, Y. & Zamore, P.D. Perspective: Machines for RNAi. Genes Dev. 19, 517-529 (2005).
-
(2005)
Genes Dev
, vol.19
, pp. 517-529
-
-
Tomari, Y.1
Zamore, P.D.2
-
5
-
-
33644519040
-
Building mammalian signalling pathways with RNAi screens
-
Moffat, J. & Sabatini, D.M. Building mammalian signalling pathways with RNAi screens. Nat. Rev. Mol. Cell Biol. 7, 177-187 (2006).
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 177-187
-
-
Moffat, J.1
Sabatini, D.M.2
-
6
-
-
0034612276
-
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
-
Clemens, J.C. et al. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad. Sci. USA 97, 6499-6503 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6499-6503
-
-
Clemens, J.C.1
-
7
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond, S.M., Bernstein, E., Beach, D. & Hannon, G.J. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404, 293-296 (2000).
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
8
-
-
0037470952
-
Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells
-
Lum, L. et al. Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science 299, 2039-2045 (2003).
-
(2003)
Science
, vol.299
, pp. 2039-2045
-
-
Lum, L.1
-
9
-
-
0242361514
-
A functional genomic analysis of cell morphology using RNA interference
-
Kiger, A.A. et al. A functional genomic analysis of cell morphology using RNA interference. J. Biol. 2, 27 (2003).
-
(2003)
J. Biol
, vol.2
, pp. 27
-
-
Kiger, A.A.1
-
10
-
-
19344370696
-
Functional dissection of an innate immune response by a genome-wide RNAi screen
-
Foley, E. & O'Farrell, P.H. Functional dissection of an innate immune response by a genome-wide RNAi screen. PLoS Biol. 2, e203 (2004).
-
(2004)
PLoS Biol
, vol.2
-
-
Foley, E.1
O'Farrell, P.H.2
-
11
-
-
0842309871
-
Genome-wide RNAi analysis of growth and viability in Drosophila cells
-
Boutros, M. et al. Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303, 832-835 (2004).
-
(2004)
Science
, vol.303
, pp. 832-835
-
-
Boutros, M.1
-
12
-
-
0037061482
-
Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
-
Ramet, M., Manfruelli, P., Pearson, A., Mathey-Prevot, B. & Ezekowitz, R.A. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 416, 644-648 (2002).
-
(2002)
Nature
, vol.416
, pp. 644-648
-
-
Ramet, M.1
Manfruelli, P.2
Pearson, A.3
Mathey-Prevot, B.4
Ezekowitz, R.A.5
-
13
-
-
33646576875
-
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
-
Feske, S. et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441, 179-185 (2006).
-
(2006)
Nature
, vol.441
, pp. 179-185
-
-
Feske, S.1
-
14
-
-
33744479684
-
2+ entry
-
2+ entry. Science 312, 1220-1223 (2006).
-
(2006)
Science
, vol.312
, pp. 1220-1223
-
-
Vig, M.1
-
16
-
-
33846466430
-
Applications of high-throughput RNA interference screens to problems in cell and developmental biology
-
Perrimon, N. & Mathey-Prevot, B. Applications of high-throughput RNA interference screens to problems in cell and developmental biology. Genetics 175, 7-16 (2007).
-
(2007)
Genetics
, vol.175
, pp. 7-16
-
-
Perrimon, N.1
Mathey-Prevot, B.2
-
17
-
-
0032443021
-
Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
-
Kennerdell, J.R. & Carthew, R.W. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 95, 1017-1026 (1998).
-
(1998)
Cell
, vol.95
, pp. 1017-1026
-
-
Kennerdell, J.R.1
Carthew, R.W.2
-
18
-
-
0033883114
-
Heritable gene silencing in Drosophila using double-stranded RNA
-
Kennerdell, J.R. & Carthew, R.W. Heritable gene silencing in Drosophila using double-stranded RNA. Nat Biotechnol 18, 896-898 (2000).
-
(2000)
Nat Biotechnol
, vol.18
, pp. 896-898
-
-
Kennerdell, J.R.1
Carthew, R.W.2
-
19
-
-
0347719384
-
A functional genomic screen for cardiogenic genes using RNA interference in developing Drosophila embryos
-
Kim, Y.O., Park, S.J., Balaban, R.S., Nirenberg, M. & Kim, Y. A functional genomic screen for cardiogenic genes using RNA interference in developing Drosophila embryos. Proc. Natl. Acad. Sci. USA 101, 159-164 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 159-164
-
-
Kim, Y.O.1
Park, S.J.2
Balaban, R.S.3
Nirenberg, M.4
Kim, Y.5
-
20
-
-
34248400087
-
RNA interference screen to identify genes required for Drosophila embryonic nervous system development
-
Koizumi, K. et al. RNA interference screen to identify genes required for Drosophila embryonic nervous system development. Proc. Natl. Acad. Sci. USA 104, 5626-5631 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 5626-5631
-
-
Koizumi, K.1
-
21
-
-
33748939584
-
Prevalence of off-target effects in Drosophila RNA interference screens
-
Ma, Y., Creanga, A., Lum, L. & Beachy, P.A. Prevalence of off-target effects in Drosophila RNA interference screens. Nature 443, 359-363 (2006).
-
(2006)
Nature
, vol.443
, pp. 359-363
-
-
Ma, Y.1
Creanga, A.2
Lum, L.3
Beachy, P.A.4
-
22
-
-
33748994797
-
Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays
-
Kulkarni, M.M. et al. Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays. Nat. Methods 3, 833-838 (2006).
-
(2006)
Nat. Methods
, vol.3
, pp. 833-838
-
-
Kulkarni, M.M.1
-
23
-
-
33749023011
-
Minimizing the risk of reporting false positives in large-scale RNAi screens
-
Echeverri, C.J. et al. Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat. Methods 3, 777-779 (2006).
-
(2006)
Nat. Methods
, vol.3
, pp. 777-779
-
-
Echeverri, C.J.1
-
24
-
-
42449103253
-
-
Matter arising: Off targets and genome scale RNAi screens in
-
Perrimon, N. & Mathey-Prevot, B. Matter arising: Off targets and genome scale RNAi screens in Drosophila. Fly 1, e1-e5 (2007).
-
(2007)
Drosophila. Fly
, vol.1
-
-
Perrimon, N.1
Mathey-Prevot, B.2
-
25
-
-
11844254453
-
High-throughput RNA interference screens in Drosophila tissue culture cells
-
Armknecht, S. et al. High-throughput RNA interference screens in Drosophila tissue culture cells. Methods Enzymol. 392, 55-73 (2005).
-
(2005)
Methods Enzymol
, vol.392
, pp. 55-73
-
-
Armknecht, S.1
-
26
-
-
33750288448
-
High-throughput approaches to dissecting MAPK signaling pathways
-
Friedman, A. & Perrimon, N. High-throughput approaches to dissecting MAPK signaling pathways. Methods 40, 262-271 (2006).
-
(2006)
Methods
, vol.40
, pp. 262-271
-
-
Friedman, A.1
Perrimon, N.2
-
27
-
-
20444506693
-
Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells
-
Kallio, J. et al. Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells. Microbes Infect. 7, 811-819 (2005).
-
(2005)
Microbes Infect
, vol.7
, pp. 811-819
-
-
Kallio, J.1
-
28
-
-
33644503868
-
Identification of pathways regulating cell size and cell-cycle progression by RNAi
-
Björklund, M. et al. Identification of pathways regulating cell size and cell-cycle progression by RNAi. Nature 439, 1009-1013 (2006).
-
(2006)
Nature
, vol.439
, pp. 1009-1013
-
-
Björklund, M.1
-
30
-
-
33646034336
-
Robust statistical methods for hit selection in RNA interference high-throughput screening experiments
-
Zhang, X.D. et al. Robust statistical methods for hit selection in RNA interference high-throughput screening experiments. Pharmacogenomics 7, 299-309 (2006).
-
(2006)
Pharmacogenomics
, vol.7
, pp. 299-309
-
-
Zhang, X.D.1
-
32
-
-
42449135932
-
-
Mathey-Prevot, B. & Perrimon, N. Regulatory RNAs: Cold Spring Harbor Symposia on Quantitative Biology LXXI. (eds. Stillman B. & Stewart D.) (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 2007).
-
Mathey-Prevot, B. & Perrimon, N. Regulatory RNAs: Cold Spring Harbor Symposia on Quantitative Biology Vol. LXXI. (eds. Stillman B. & Stewart D.) (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 2007).
-
-
-
-
33
-
-
33747818012
-
RNA interference pinpoints regulators of cell size and the cell cycle
-
Cully, M.J. & Leevers, S.J. RNA interference pinpoints regulators of cell size and the cell cycle. Genome Biol. 7, 219 (2006).
-
(2006)
Genome Biol
, vol.7
, pp. 219
-
-
Cully, M.J.1
Leevers, S.J.2
-
34
-
-
33646187810
-
High-throughput RNAi screening in cultured cells: A user's guide
-
Echeveni, C.J. & Perrimon, N. High-throughput RNAi screening in cultured cells: A user's guide. Nat. Rev. Genet. 7, 373-384 (2006).
-
(2006)
Nat. Rev. Genet
, vol.7
, pp. 373-384
-
-
Echeveni, C.J.1
Perrimon, N.2
-
35
-
-
0742316351
-
An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome
-
Hild, M. et al. An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome. Genome Biol. 5, R3 (2003).
-
(2003)
Genome Biol
, vol.5
-
-
Hild, M.1
-
36
-
-
32344448950
-
Statistical practice in high-throughput screening data analysis
-
Malo, N., Hanley, J.A., Cerquozzi, S., Pelletier, J. & Nadon, R. Statistical practice in high-throughput screening data analysis. Nat. Biotechnol. 24, 167-175 (2006).
-
(2006)
Nat. Biotechnol
, vol.24
, pp. 167-175
-
-
Malo, N.1
Hanley, J.A.2
Cerquozzi, S.3
Pelletier, J.4
Nadon, R.5
-
37
-
-
34547840198
-
An efficient method for the detection and elimination of systematic error in high-throughput screening
-
Makarenkov, V. et al. An efficient method for the detection and elimination of systematic error in high-throughput screening. Bioinformatics 23, 1648-1657 (2007).
-
(2007)
Bioinformatics
, vol.23
, pp. 1648-1657
-
-
Makarenkov, V.1
-
38
-
-
33645756545
-
-
Springer, New York
-
Gentleman, R., Carey, V.J., Huber, W., Irizarri, R. & Dudoit, S. Bioinformatics and Computational Biology Solutions using R and Bioconductor (Springer, New York, 2005).
-
(2005)
Bioinformatics and Computational Biology Solutions using R and Bioconductor
-
-
Gentleman, R.1
Carey, V.J.2
Huber, W.3
Irizarri, R.4
Dudoit, S.5
-
39
-
-
33644876926
-
FLIGHT: Database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets
-
Sims, D., Bursteinas, B., Gao, Q., Zvelebil, M. & Baum, B. FLIGHT: database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets. Nucleic Acids Res. 34, D479-D483 (2006).
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Sims, D.1
Bursteinas, B.2
Gao, Q.3
Zvelebil, M.4
Baum, B.5
-
40
-
-
33644873679
-
FlyRNAi: The Drosophila RNAi screening center database
-
Flockhart, I. et al. FlyRNAi: The Drosophila RNAi screening center database. Nucleic Acids Res. 34, D489-D494 (2006).
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Flockhart, I.1
-
41
-
-
0033990048
-
Primer3 on the WWW for general users and for biologist programmers
-
Rozen, S. & Skaletsky, H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 132, 365-386 (2000).
-
(2000)
Methods Mol. Biol
, vol.132
, pp. 365-386
-
-
Rozen, S.1
Skaletsky, H.2
-
42
-
-
33845792555
-
CellProfiler: Image analysis software for identifying and quantifying cell phenotypes
-
Carpenter, A.E. et al. CellProfiler: Image analysis software for identifying and quantifying cell phenotypes. Genome Biol. 7, R100 (2006).
-
(2006)
Genome Biol
, vol.7
-
-
Carpenter, A.E.1
-
43
-
-
35548931351
-
Efficient tests for normality, homoscedasticity and serial independence of regression residuals
-
Bera, A.K. & Jarque, C.M. Efficient tests for normality, homoscedasticity and serial independence of regression residuals. Econ. Lett. 6, 255-259 (1980).
-
(1980)
Econ. Lett
, vol.6
, pp. 255-259
-
-
Bera, A.K.1
Jarque, C.M.2
-
44
-
-
33750887331
-
A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling
-
Friedman, A. & Perrimon, N. A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature 444, 230-234 (2006).
-
(2006)
Nature
, vol.444
, pp. 230-234
-
-
Friedman, A.1
Perrimon, N.2
-
45
-
-
33846062023
-
Database resources of the National Center for Biotechnology Information
-
Wheeler, D.L. et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 35, D5-D12 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Wheeler, D.L.1
-
46
-
-
13444256478
-
Inparanoid: A comprehensive database of eukaryotic orthologs
-
O'Brien, K.P., Remm, M. & Sonnhammer, E.L. Inparanoid: A comprehensive database of eukaryotic orthologs. Nucleic Acids Res. 33, D476-D480 (2005).
-
(2005)
Nucleic Acids Res
, vol.33
-
-
O'Brien, K.P.1
Remm, M.2
Sonnhammer, E.L.3
-
47
-
-
0035963414
-
Protein dispensability and rate of evolution
-
Hirsh, A.E. & Fraser, H.B. Protein dispensability and rate of evolution. Nature 411, 1046-1049 (2001).
-
(2001)
Nature
, vol.411
, pp. 1046-1049
-
-
Hirsh, A.E.1
Fraser, H.B.2
-
48
-
-
0036078078
-
Essential genes are more evolutionarily conserved than are nonessential genes in bacteria
-
Jordan, I.K., Rogozin, I.B., Wolf, Y.I. & Koonin, E.V. Essential genes are more evolutionarily conserved than are nonessential genes in bacteria. Genome Res. 12, 962-968 (2002).
-
(2002)
Genome Res
, vol.12
, pp. 962-968
-
-
Jordan, I.K.1
Rogozin, I.B.2
Wolf, Y.I.3
Koonin, E.V.4
-
49
-
-
33846040145
-
FlyBase: Genomes by the dozen
-
Crosby, M.A., Goodman, J.L., Strelets, V.B., Zhang, P. & Gelbart, W.M. FlyBase: Genomes by the dozen. Nucleic Acids Res. 35, D486-D491 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Crosby, M.A.1
Goodman, J.L.2
Strelets, V.B.3
Zhang, P.4
Gelbart, W.M.5
-
50
-
-
33644873681
-
FlyBase: Anatomical data, images and queries
-
Grumbling, G. & Strelets, V. FlyBase: Anatomical data, images and queries. Nucleic Acids Res. 34, D484-488 (2006).
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Grumbling, G.1
Strelets, V.2
-
51
-
-
33646380337
-
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila
-
Pacifico, S. et al. A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila. BMC Bioinformatics 7, 195 (2006).
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 195
-
-
Pacifico, S.1
-
52
-
-
18244400410
-
Functional genomic analysis of the Wnt-wingless signaling pathway
-
DasGupta, R., Kaykas, A., Moon, R.T. & Perrimon, N. Functional genomic analysis of the Wnt-wingless signaling pathway. Science 308, 826-833 (2006).
-
(2006)
Science
, vol.308
, pp. 826-833
-
-
DasGupta, R.1
Kaykas, A.2
Moon, R.T.3
Perrimon, N.4
-
53
-
-
0015328565
-
Cell lines derived from late embryonic stages of Drosophila melanogaster
-
Schneider, I. Cell lines derived from late embryonic stages of Drosophila melanogaster. J. Embryol. Exp. Morphol. 27, 353-365 (1972).
-
(1972)
J. Embryol. Exp. Morphol
, vol.27
, pp. 353-365
-
-
Schneider, I.1
-
54
-
-
0033610897
-
Identification and characterization of a novel line of Drosophila Schneider S2 cells that respond to wingless signaling
-
Yanagawa, S., Lee, J.S. & Ishimoto, A. Identification and characterization of a novel line of Drosophila Schneider S2 cells that respond to wingless signaling. J. Biol. Chem. 273, 32353-32359 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 32353-32359
-
-
Yanagawa, S.1
Lee, J.S.2
Ishimoto, A.3
-
55
-
-
0014696872
-
Isolation, in tissue culture, of Drosophila melanogaster cell lines]
-
Echalier, G. & Ohanessian, A. [Isolation, in tissue culture, of Drosophila melanogaster cell lines]. C. R. Acad. Sci. Hebd. Seances. Acad. Sci. D 268, 1771-1773 (1969).
-
(1969)
C. R. Acad. Sci. Hebd. Seances. Acad. Sci. D
, vol.268
, pp. 1771-1773
-
-
Echalier, G.1
Ohanessian, A.2
-
56
-
-
0018868218
-
Evidence for endogenous reovirus-like particles in a tissue culture cell line from Drosophila melanogaster
-
Haars, R., Zentgraf, H., Gateff, E. & Bautz, F.A. Evidence for endogenous reovirus-like particles in a tissue culture cell line from Drosophila melanogaster. Virology 101, 124-130 (1980).
-
(1980)
Virology
, vol.101
, pp. 124-130
-
-
Haars, R.1
Zentgraf, H.2
Gateff, E.3
Bautz, F.A.4
-
57
-
-
0028234384
-
Newly established cell lines from Drosophila larval CNS express neural specific characteristics
-
Ui, K. et al. Newly established cell lines from Drosophila larval CNS express neural specific characteristics. In Vitro Cell. Dev. Biol. Anim. 30A, 209-216 (1994).
-
(1994)
In Vitro Cell. Dev. Biol. Anim
, vol.30 A
, pp. 209-216
-
-
Ui, K.1
-
58
-
-
0023432747
-
Cell lines from imaginal discs of Drosophila melanogaster
-
Ui, K., Ueda, R. & Miyake, T. Cell lines from imaginal discs of Drosophila melanogaster. In Vitro Cell. Dev. Biol. 23, 707-711 (1987).
-
(1987)
In Vitro Cell. Dev. Biol
, vol.23
, pp. 707-711
-
-
Ui, K.1
Ueda, R.2
Miyake, T.3
|