Automated screening of neurite outgrowth

Journal of Biomolecular Screening

Volumn 8, Issue 1, 2003, Pages 7-18

  Ramm, Peter ^a   Alexandrov, Yuriy ^a   Cholewinski, Andrzej ^a   Cybuch, Yuriy ^a   Nadon, Robert ^a   Soltys, Bohdan J ^a  

^a Imaging Research Inc   (Canada)

Author keywords

Cell screening; Image analysis; Imaging system; Neurite; Neuro 2a cells

Indexed keywords

NEUROFILAMENT PROTEIN; RETINOIC ACID;

ACCURACY; ALGORITHM; ANIMAL CELL; ARTICLE; AUTOANALYSIS; CELL COUNT; CELL SCREENING; CELL SIZE; CONTROLLED STUDY; CYTOSKELETON; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; MOUSE; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; NONHUMAN; PERIKARYON; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RELIABILITY; VALIDATION PROCESS; ANIMAL; AUTOMATION; CYTOLOGY; DIAGNOSTIC IMAGING; METABOLISM; NERVE CELL; NEURITE;

ANIMALS; AUTOMATION; DIAGNOSTIC IMAGING; MICE; NEURITES; NEURONS;

EID: 0041968413     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057102239779     Document Type: Article

References (38)

1. Guyer A, Schwartz M: The use of image analysis for measuring neuritic outgrowth from goldfish regenerating retinal explants. J Neurosci Methods 1983;7:275.
2. Bonyhady RE, Hendry IA, Hill CE, Watters DJ: An analysis of peripheral neuronal survival factors present in muscle. J Neurosci Res 1985;13:357.
3. Ford-Holevinski TS, Dahlberg TA, Agranoff BW: A microcomputer-based image analyzer for quantitating neurite outgrowth. Brain Res 1986;368:339.
4. Walicke P, Cowan WM, Ueno N, Baird A, Guillemin R: Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. Proc Natl Acad Sci USA 1986;83:3012.
5. Unsicker K, Reichert-Preibsch H, Schmidt R, Pettmann B, Labourdette G, Sensenbrenner M: Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons. Proc Natl Acad Sci USA 1987;84:5459.
6. Sano M, Kato K, Totsuka T, Katoh-Semba R: A convenient bioassay for NGF using a new subline of PC12 pheochromocytoma cells (PC12D). Brain Res 1988;459:404.
7. Matsumoto T, Oshima K, Miyamoto A, Sakurai M, Goto M, Hayashi S: Image analysis of CNS neurotrophic factor effects on neuronal survival and neurite outgrowth. J Neurosci Methods 1990;31:153.
8. Gil OD, Zanazzi G, Struyk AF, Salzer JL: Neurotrimin mediates bifunctional effects on neurite outgrowth via homophilic and heterophilic interactions. J Neurosci 1998;15:9312.
9. Wu YY, Bradshaw RA: Activation of the Stat3 signaling pathway is required for differentiation by interleukin-6 in PC12-E2 cells. J Biol Chem 2000;275:2147.
10. Masseroli M, Bollea A, Forloni G: Quantitative morphology and shape classification of neurons by computerized image analysis. Comp Meth Prog Biomed 1993;41:89.
11. Siklos L, Kuhnt U: Algorithm for semi-automatic sorting of objects to specified tissue domains: an aid for co-ordinating morphometric data with identified tissue components. J Neurosci Methods 1993;46:217.
12. Malgrange B, Delree P, Rigo JM, Baron H, Moonen G: Image analysis of neuritic regeneration by adult rat dorsal root ganglion neurons in culture: quantification of the neurotoxicity of anticancer agents and of its prevention by nerve growth factor or basic fibroblast growth factor but not brain-derived neurotrophic factor or neurotrophin-3. J Neurosci Methods 1994;53:111.
13. Mezin P, Tenaud C, Bosson JL, Stoebner P: Morphometric analysis of the peripheral nerve: advantages of the semi-automated interactive method. J Neurosci Methods 1994;51:163.
14. Turner JN, Szarowski DH, Turner TJ, Ancin H, Lin WC, Roysam B, et al: Three-dimensional imaging and image analysis of hippocampal neurons: confocal and digitally enhanced wide field microscopy. Microsc Res Tech 1994;29:269.
15. de Medinaceli L: Interpreting nerve morphometry data after experimental traumatic lesions. J Neurosci Methods 1995;58:29.
16. Pauwels O, Atassi G, Kiss R: Combination of computerized morphonuclear and multivariate analyses to characterize in vitro the antineoplastic effect of alkylating agents. J Pharmacol Toxicol Methods 1995;33:35.
17. Ventimiglia R, Jones BE, Moller A: A quantitative method for morphometric analysis in neuronal cell culture: unbiased estimation of neuron area and number of branch points. J Neurosci Methods 1995;57:63.
18. Stahlhut M, Berezin V, Bock E, Ternaux JP: NCAM-fibronectin-type-III- domain substrata with and without a six-amino-acid-long proline-rich insert increase the dendritic and axonal arborization of spinal motoneurons. J Neurosci Res 1997;48:112.
19. Isaacs KR, Hanbauer I, Jacobowitz DM: A method for the rapid analysis of neuronal proportions and neurite morphology in primary cultures. Exp Neurol 1998;149:464.
20. Bilsland J, Rigby M, Young L, Harper S: A rapid method for semi-quantitative analysis of neurite outgrowth from chick DRG explants using image analysis. J Neurosci Methods 1999;92:75.
21. Pollack S, Young L, Bilsland J, Wilkie N, Ellis S, Hefti F, et al: The staurosporine-like compound L-753,000 (NB-506) potentiates the neurotrophic effects of neurotrophin-3 by acting selectively at the TrkA receptor. Mol Pharmacol 1999;56:185.
22. Ronn LC, Ralets I, Hartz BP, Bech M, Berezin A, Berezin V, et al: A simple procedure for quantification of neurite outgrowth based on stereological principles. J Neurosci Methods 2000;100:25.
23. Shea TB, Fischer I, Sapirstein VS: Effect of retinoic acid on growth and morphological differentiation of mouse NB2a neuroblastoma cells in culture. Dev Brain Res 1985;21:307.
24. Kozireski-Chuback D, Wu G, Ledeen RW: Axonogenesis in neuro-2a cells correlates with GM1 upregulation in the nuclear and plasma membranes. J Neurosci Res 1999;57:541.
25. Burstein DE, Greene LA: Evidence for RNA synthesis-dependent and - independent pathways in stimulation of neurite outgrowth by nerve growth factor. Proc Natl Acad Sci USA 1978;75:6059.
26. Gill JS, Schenone AE, Podratz JL, Windebank AJ: Autocrine regulation of neurite outgrowth from PC12 cells by nerve growth factor. Brain Res Mol Brain Res 1998;57:123.
27. Gysbers JW, Guarnieri S, Mariggio MA, Pietrangelo T, Fano G, Rathbone MP: Extracellular guanosine 5′ triphosphate enhances nerve growth factor-induced neurite outgrowth via increases in intracellular calcium. Neuroscience 2000;96:817.
28. Jiang ZG, Smith RA, Neilson MM: The effects of nerve growth factor on neurite outgrowth from cultured adult and aged mouse sensory neurons. Brain Res Dev Brain Res 1995;85:212.
29. Kawa A, Stahlhut M, Berezin A, Bock E, Berezin V: A simple procedure for morphometric analysis of processes and growth cones of neurons in culture using parameters derived from the contour and convex hull of the object. J Neurosci Methods 1998;79:53.
30. Leoni C, Menegon A, Benfenati F, Toniolo D, Pennuto M, Valtorta F: Neurite extension occurs in the absence of regulated exocytosis in PC12 subclones. Mol Biol Cell 1999;10:2919.
31. Morfini G, Quiroga S, Rosa A, Kosik K, Caceres A: Suppression of K1F2 in PC12 cells alters the distribution of a growth cone nonsynaptic membrane receptor and inhibits neurite extension. J Cell Biol 1997;138:657.
32. Osen-Sand A, Catsicas M, Staple JK, Jones KA, Ayala G, Knowles J, et al: Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo. Nature 1993;364:445.
33. Riederer BM, Pellier V, Antonsson B, Di Paolo G, Stimpson SA, Lutjens R, et al: Regulation of microtubule dynamics by the neuronal growth-associated protein SCG10. Proc Natl Acad Sci USA 1997;94:741.
34. Riboni L, Prinetti A, Bassi R, Caminiti A, Tettamanti G: A mediator role of ceramide in the regulation of neuroblastoma neuro2a cell differentiation. J Biol Chem 1995;270:26868.
35. Singleton DW, Lu CL, Colella R, Roisen FJ: Promotion of neurite outgrowth by protein kinase inhibitors and ganglioside GM1 in neuroblastoma cells involves MAP kinase ERK1/2. Int J Develop Neurosci 2000;18:797.
36. Yip PM, Zhao X, Montgomery AM, Siu CH: The Arg-Gly-Asp motif in the cell adhesion molecule L1 promotes neurite outgrowth via interaction with the alphavbeta3 integrin. Mol Biol Cell 1998;9:277.
37. Ramm P: Imaging systems in assay screening. Drug Discovery Today 1999;4:401.
38. Blanco V, Lopez Camelo J, Carri NG: Growth inhibition, morphological differentiation and stimulation of survival in neuronal cell type (Neuro-2a) treated with trophic molecules. Cell Biol Int 2001;25:909.