Chemical genetics to identify NFAT inhibitors: Potential of targeting calcium mobilization in immunosuppression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 24, 2004, Pages 8969-8974

  Venkatesh, Natarajan ^a   Feng, Yan ^a   DeDecker, Brian ^a   Yacono, Patrick ^a   Golan, David ^a   Mitchison, Timothy ^a   McKeon, Frank ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Capacitative calcium entry; Cyclosporin A; Store operated calcium channels

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; TACROLIMUS; TRANSCRIPTION FACTOR NFAT INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CHEMICAL GENETICS; DRUG SCREENING; HELA CELL; HUMAN; HUMAN CELL; IC 50; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE ACTIVATION;

ANIMALS; CALCINEURIN; CALCIUM; CALCIUM CHANNELS; CELL LINE; CELL NUCLEUS; COMBINATORIAL CHEMISTRY TECHNIQUES; CRICETINAE; CYCLOSPORINE; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INHIBITORY CONCENTRATION 50; INTERLEUKIN-2; MICE; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; ORGANIC CHEMICALS; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 2942632790     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0402803101     Document Type: Article

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