How to create the vascular tree? (Latest) help from the zebrafish

Pharmacology and Therapeutics

Volumn 118, Issue 2, 2008, Pages 206-230

  Baldessari, Danila ^a   Mione, Marina ^a  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

Angiogenesis; Genetic and chemical screens; Human disease; Lymphatic and blood vessels; Tumours; Vasculogenesis; Zebrafish

Indexed keywords

3 [4 METHYL 2 (2 OXO 3 INDOLINYLMETHYLIDENYL) 3 PYRROLYL]PROPIONIC ACID; ANTISENSE OLIGONUCLEOTIDE; QUANTUM DOT; SEMAXANIB;

ANGIOGENESIS; ARTERY; BLOOD VESSEL DIAMETER; CANCER MODEL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL JUNCTION; CELL MIGRATION; CELL THERAPY; DISEASE MODEL; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE TECHNOLOGY; GENETIC SCREENING; IMAGING; KNOCKOUT GENE; LYMPHATIC SYSTEM; MESODERM; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; REGENERATION; REVIEW; TRANSGENE; TUMOR VASCULARIZATION; VEIN; ZEBRA FISH;

ANIMALS; BLOOD VESSELS; CARDIOVASCULAR SYSTEM; DATABASES, FACTUAL; HUMANS; ZEBRAFISH;

EID: 43149098488     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2008.02.010     Document Type: Review

References (315)

1. Abdelilah S., Mountcastle-Shah E., Harvey M., Solnica-Krezel L., Schier A.F., Stemple D.L., et al. Mutations affecting neural survival in the zebrafish danio rerio. Development 123 (1996) 217-227
2. Ahuja M.R., and Anders F. A genetic concept of the origin of cancer, based in part upon studies of neoplasms in fishes. Prog Exp Tumor Res 20 (1976) 380-397
3. Airaksinen M.S., Holm L., and Hatinen T. Evolution of the GDNF family ligands and receptors. Brain Behav Evol 68 3 (2006) 181-190
4. Alexander J., Stainier D.Y., and Yelon D. Screening mosaic F1 females for mutations affecting zebrafish heart induction and patterning. Dev Genet 22 3 (1998) 288-299
5. Amatruda J.F., Shepard J.L., Stern H.M., and Zon L.I. Zebrafish as a cancer model system. Cancer Cell 1 3 (2002) 229-231
6. Amsterdam A. Insertional mutagenesis in zebrafish. Dev Dyn 228 3 (2003) 523-534
7. Amsterdam A., and Becker T.S. Transgenes as screening tools to probe and manipulate the zebrafish genome. Dev Dyn 234 2 (2005) 255-268
8. Amsterdam A., and Hopkins N. Retrovirus-mediated insertional mutagenesis in zebrafish. Methods Cell Biol 60 (1999) 87-98
9. Amsterdam A., and Hopkins N. Mutagenesis strategies in zebrafish for identifying genes involved in development and disease. Trends Genet 22 9 (2006) 473-478
10. Amsterdam A., Lin S., Moss L.G., and Hopkins N. Requirements for green fluorescent protein detection in transgenic zebrafish embryos. Gene 173 1 Spec No (1996) 99-103
11. Amsterdam A., Burgess S., Golling G., Chen W., Sun Z., Townsend K., et al. A large-scale insertional mutagenesis screen in zebrafish. Genes Dev 13 20 (1999) 2713-2724
12. Amsterdam A., Nissen R.M., Sun Z., Swindell E.C., Farrington S., and Hopkins N. Identification of 315 genes essential for early zebrafish development. Proc Natl Acad Sci U S A 101 35 (2004) 12792-12797
13. Arnaout R., Ferrer T., Huisken J., Spitzer K., Stainier D.Y., Tristani-Firouzi M., et al. Zebrafish model for human long QT syndrome. Proc Natl Acad Sci U S A 104 27 (2007) 11316-11321
14. Baker K., Warren K.S., Yellen G., and Fishman M.C. Defective "pacemaker" current (Ih) in a zebrafish mutant with a slow heart rate. Proc Natl Acad Sci U S A 94 9 (1997) 4554-4559
15. Bahary N., Davidson A., Ransom D., Shepard J., Stern H., Trede N., et al. The Zon laboratory guide to positional cloning in zebrafish. Methods Cell Biol 77 (2004) 305-329
16. Baluk P., Fuxe J., Hashizume H., Romano T., Lashnits E., Butz S., et al. Functionally specialized junctions between endothelial cells of lymphatic vessels. J Exp Med 204 10 (2007) 2349-2362 (Oct. 1)
17. Bartman T., Walsh E.C., Wen K.K., McKane M., Ren J., Alexander J., et al. Early myocardial function affects endocardial cushion development in zebrafish. PLoS Biol 2 5 (2004) E129
18. Bayliss P.E., Bellavance K.L., Whitehead G.G., Abrams J.M., Aegerter S., Robbins H.S., et al. Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish. Nat Chem Biol 2 5 (2006) 265-273
19. Bazzoni G., and Dejana E. Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol Rev 84 3 (2004) 869-901
20. Beckwith L.G., Moore J.L., Tsao-Wu G.S., Harshbarger J.C., and Cheng K.C. Ethylnitrosourea induces neoplasia in zebrafish (Danio rerio). Lab Invest 80 3 (2000) 379-385
21. Bedell V.M., Yeo S.Y., Park K.W., Chung J., Seth P., Shivalingappa V., et al. Roundabout4 is essential for angiogenesis in vivo. Proc Natl Acad Sci U S A 102 18 (2005) 6373-6378
22. Beis D., Bartman T., Jin S.W., Scott I.C., D'Amico L.A., Ober E.A., et al. Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development 132 18 (2005) 4193-4204
23. Belleri M., Ribatti D., Nicoli S., Cotelli F., Forti L., Vannini V., et al. Antiangiogenic and vascular-targeting activity of the microtubule-destabilizing trans-resveratrol derivative 3,5,4'-trimethoxystilbene. Mol Pharmacol 67 5 (2005) 1451-1459
24. Bendig G., Grimmler M., Huttner I.G., Wessels G., Dahme T., Just S., et al. Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart. Genes Dev 20 17 (2006) 2361-2372
25. Benjamin L.E., Hemo I., and Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125 9 (1998) 1591-1598
26. Berdougo E., Coleman H., Lee D.H., Stainier D.Y., and Yelon D. Mutation of weak atrium/atrial myosin heavy chain disrupts atrial function and influences ventricular morphogenesis in zebrafish. Development 130 24 (2003) 6121-6129
27. Betsholtz C., Lindblom P., and Gerhardt H. Role of pericytes in vascular morphogenesis. Exs 94 (2005) 115-125
28. Bielenberg D.R., and Klagsbrun M. Targeting endothelial and tumor cells with semaphorins. Cancer Metastasis Rev 26 3-4 (2007) 421-431 (Dec)
29. Brakenhielm E., Cao R., and Cao Y. Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes. Faseb J 15 10 (2001) 1798-1800
30. Brand M., Heisenberg C.P., Warga R.M., Pelegri F., Karlstrom R.O., Beuchle D., et al. Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development 123 (1996) 129-142
31. Brown L.A., Rodaway A.R., Schilling T.F., Jowett T., Ingham P.W., Patient R.K., et al. Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos. Mech Dev 90 2 (2000) 237-252
32. Brownlie A., Donovan A., Pratt S.J., Paw B.H., Oates A.C., Brugnara C., et al. Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nat Genet 20 3 (1998) 244-250
33. Brownlie A., Hersey C., Oates A.C., Paw B.H., Falick A.M., Witkowska H.E., et al. Characterization of embryonic globin genes of the zebrafish. Dev Biol 255 1 (2003) 48-61
34. Bruchez Jr. M., Moronne M., Gin P., Weiss S., and Alivisatos A.P. Semiconductor nanocrystals as fluorescent biological labels. Science 281 5385 (1998) 2013-2016
35. Bussmann J., Bakkers J., and Schulte-Merker S. Early endocardial morphogenesis requires Scl/Tal1. PLoS Genet 3 8 (2007) e140
36. Carmeliet P. Blood vessels and nerves: common signals, pathways and diseases. Nat Rev Genet 4 9 (2003) 710-720
37. Carmeliet P., and Tessier-Lavigne M. Common mechanisms of nerve and blood vessel wiring. Nature 436 7048 (2005) 193-200
38. Carmeliet P., Ferreira V., Breier G., Pollefeyt S., Kieckens L., Gertsenstein M., et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380 6573 (1996) 435-439
39. Chakrabarti S., Streisinger G., Singer F., and Walker C. Frequency of gamma-ray induced specific locus and recessive lethal mutations in mature germ cells of the zebrafish, Brachydanio rerio. Genetics 103 1 (1983) 109-123
40. Chan J., Bayliss P.E., Wood J.M., and Roberts T.M. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach. Cancer Cell 1 3 (2002) 257-267
41. Chatterjee B., Chin A.J., Valdimarsson G., Finis C., Sonntag J.M., Choi B.Y., et al. Developmental regulation and expression of the zebrafish connexin43 gene. Dev Dyn 233 3 (2005) 890-906
42. Chen J.N., Haffter P., Odenthal J., Vogelsang E., Brand M., van Eeden F.J., et al. Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development 123 (1996) 293-302
43. Chen J.N., van Bebber F., Goldstein A.M., Serluca F.C., Jackson D., Childs S., et al. Genetic steps to organ laterality in zebrafish. Comp Funct Genomics 2 2 (2001) 60-68
44. Chen E., Stringer S.E., Rusch M.A., Selleck S.B., and Ekker S.C. A unique role for 6-O sulfation modification in zebrafish vascular development. Dev Biol 284 2 (2005) 364-376
45. Cheng S.H., Chan P.K., and Wu R.S. The use of microangiography in detecting aberrant vasculature in zebrafish embryos exposed to cadmium. Aquat Toxicol 52 1 (2001) 61-71
46. Childs S., Weinstein B.M., Mohideen M.A., Donohue S., Bonkovsky H., and Fishman M.C. Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria. Curr Biol 10 16 (2000) 1001-1004
47. Childs S., Chen J.N., Garrity D.M., and Fishman M.C. Patterning of angiogenesis in the zebrafish embryo. Development 129 4 (2002) 973-982
48. Chittenden T.W., Claes F., Lanahan A.A., Autiero M., Palac R.T., Tkachenko E.V., et al. Selective regulation of arterial branching morphogenesis by synectin. Dev Cell 10 6 (2006) 783-795
49. Cleaver O., and Krieg P.A. VEGF mediates angioblast migration during development of the dorsal aorta in Xenopus. Development 125 19 (1998) 3905-3914
50. Covassin L., Amigo J.D., Suzuki K., Teplyuk V., Straubhaar J., and Lawson N.D. Global analysis of hematopoietic and vascular endothelial gene expression by tissue specific microarray profiling in zebrafish. Dev Biol 299 2 (2006) 551-562
51. Crosier P.S., Kalev-Zylinska M.L., Hall C.J., Flores M.V., Horsfield J.A., and Crosier K.E. Pathways in blood and vessel development revealed through zebrafish genetics. Int J Dev Biol 46 4 (2002) 493-502
52. Cross L.M., Cook M.A., Lin S., Chen J.N., and Rubinstein A.L. Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay. Arterioscler Thromb Vasc Biol 23 5 (2003) 911-912
53. Curado S., and Stainier D.Y. The HeArt of regeneration. Cell 127 3 (2006) 462-464
54. Dejana E. Endothelial cell-cell junctions: happy together. Nat Rev Mol Cell Biol 5 4 (2004) 261-270
55. Dethleffsen K., Heinrich G., Lauth M., Knapik E.W., and Meyer M. Insert-containing neurotrophins in teleost fish and their relationship to nerve growth factor. Mol Cell Neurosci 24 2 (2003) 380-394
56. Dodd A., Chambers S.P., and Love D.R. Short interfering RNA-mediated gene targeting in the zebrafish. FEBS Lett 561 1-3 (2004) 89-93
57. Donovan A., Brownlie A., Zhou Y., Shepard J., Pratt S.J., Moynihan J., et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 403 6771 (2000) 776-781
58. Donovan A., Brownlie A., Dorschner M.O., Zhou Y., Pratt S.J., Paw B.H., et al. The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood 100 13 (2002) 4655-4659
59. Dooley K., and Zon L.I. Zebrafish: a model system for the study of human disease. Curr Opin Genet Dev 10 3 (2000) 252-256
60. Draper B.W., McCallum C.M., Stout J.L., Slade A.J., and Moens C.B. A high-throughput method for identifying N-ethyl-N-nitrosourea (ENU)-induced point mutations in zebrafish. Methods Cell Biol 77 (2004) 91-112
61. Driever W., and Fishman M.C. The zebrafish: heritable disorders in transparent embryos. J Clin Invest 97 8 (1996) 1788-1794
62. Driever W., Solnica-Krezel L., Schier A.F., Neuhauss S.C., Malicki J., Stemple D.L., et al. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 123 (1996) 37-46
63. Dube A., Akbarali Y., Sato T.N., Libermann T.A., and Oettgen P. Role of the Ets transcription factors in the regulation of the vascular-specific Tie2 gene. Circ Res 84 10 (1999) 1177-1185
64. Dubertret B., Skourides P., Norris D.J., Noireaux V., Brivanlou A.H., and Libchaber A. In vivo imaging of quantum dots encapsulated in phospholipid micelles. Science 298 5599 (2002) 1759-1762
65. Ebert A.M., Hume G.L., Warren K.S., Cook N.P., Burns C.G., Mohideen M.A., et al. Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts. Proc Natl Acad Sci U S A 102 49 (2005) 17705-17710
66. Eichmann A., Le Noble F., Autiero M., and Carmeliet P. Guidance of vascular and neural network formation. Curr Opin Neurobiol 15 1 (2005) 108-115
67. Eichmann A., Makinen T., and Alitalo K. Neural guidance molecules regulate vascular remodeling and vessel navigation. Genes Dev 19 9 (2005) 1013-1021
68. Eisen J.S. Zebrafish make a big splash. Cell 87 6 (1996) 969-977
69. Ellingsen S., Laplante M.A., Konig M., Kikuta H., Furmanek T., Hoivik E.A., et al. Large-scale enhancer detection in the zebrafish genome. Development 132 17 (2005) 3799-3811
70. Feldner J., Becker T., Goishi K., Schweitzer J., Lee P., Schachner M., et al. Neuropilin-1a is involved in trunk motor axon outgrowth in embryonic zebrafish. Dev Dyn 234 3 (2005) 535-549
71. Feng J., Cheng S.H., Chan P.K., and Ip H.H. Reconstruction and representation of caudal vasculature of zebrafish embryo from confocal scanning laser fluorescence microscopic images. Comput Biol Med 35 10 (2005) 915-931
72. Ferrara N., Carver-Moore K., Chen H., Dowd M., Lu L., O'Shea K.S., et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380 6573 (1996) 439-442
73. Fricke C., and Chien C.B. Cloning of full-length zebrafish dcc and expression analysis during embryonic and early larval development. Dev Dyn 234 3 (2005) 732-739
74. Fritsche R., Schwerte T., and Pelster B. Nitric oxide and vascular reactivity in developing zebrafish, Danio rerio. Am J Physiol Regul Integr Comp Physiol 279 6 (2000) R2200-R2207
75. Gaiano N., Amsterdam A., Kawakami K., Allende M., Becker T., and Hopkins N. Insertional mutagenesis and rapid cloning of essential genes in zebrafish. Nature 383 6603 (1996) 829-832
76. Gale N.W., and Yancopoulos G.D. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev 13 9 (1999) 1055-1066
77. Garrity D.M., Childs S., and Fishman M.C. The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome. Development 129 19 (2002) 4635-4645
78. Gerull B., Gramlich M., Atherton J., McNabb M., Trombitas K., Sasse-Klaassen S., et al. Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy. Nat Genet 30 2 (2002) 201-204
79. Golling G., Amsterdam A., Sun Z., Antonelli M., Maldonado E., Chen W., et al. Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nat Genet 31 2 (2002) 135-140
80. Gordon M. The hereditary basis for melanosis in hybrids of Mexican killifishes. Proc Natl Acad Sci U S A 17 5 (1931) 276-280
81. Granato M., van Eeden F.J., Schach U., Trowe T., Brand M., Furutani-Seiki M., et al. Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. Development 123 (1996) 399-413
82. Gray M., Moens C.B., Amacher S.L., Eisen J.S., and Beattie C.E. Zebrafish deadly seven functions in neurogenesis. Dev Biol 237 2 (2001) 306-323
83. Griffin K.J., Amacher S.L., Kimmel C.B., and Kimelman D. Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes. Development 125 17 (1998) 3379-3388
84. Grunwald D.J., and Streisinger G. Induction of recessive lethal and specific locus mutations in the zebrafish with ethyl nitrosourea. Genet Res 59 2 (1992) 103-116
85. Gulati-Leekha A., and Goldman D. A reporter-assisted mutagenesis screen using alpha 1-tubulin-GFP transgenic zebrafish uncovers missteps during neuronal development and axonogenesis. Dev Biol 296 1 (2006) 29-47
86. Gupta S., Zhu H., Zon L.I., and Evans T. BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis. Development 133 11 (2006) 2177-2187
87. Habeck H., Odenthal J., Walderich B., Maischein H., and Schulte-Merker S. Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Curr Biol 12 16 (2002) 1405-1412
88. Haffter P., Granato M., Brand M., Mullins M.C., Hammerschmidt M., Kane D.A., et al. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123 (1996) 1-36
89. Harvey R.P. Patterning the vertebrate heart. Nat Rev Genet 3 7 (2002) 544-556
90. Heicklen-Klein A., and Evans T. T-box binding sites are required for activity of a cardiac GATA-4 enhancer. Dev Biol 267 2 (2004) 490-504
91. Ho R.K., and Kane D.A. Cell-autonomous action of zebrafish spt-1 mutation in specific mesodermal precursors. Nature 348 6303 (1990) 728-730
92. Ho Y.L., Lin Y.H., Tsai I.J., Hsieh F.J., and Tsai H.J. In vivo assessment of cardiac morphology and function in heart-specific green fluorescent zebrafish. J Formos Med Assoc 106 3 (2007) 181-186
93. Hoch R.V., and Soriano P. Roles of PDGF in animal development. Development 130 20 (2003) 4769-4784
94. Holley S.A., Geisler R., and Nusslein-Volhard C. Control of her1 expression during zebrafish somitogenesis by a delta-dependent oscillator and an independent wave-front activity. Genes Dev 14 13 (2000) 1678-1690
95. Honma Y., Araki T., Gianino S., Bruce A., Heuckeroth R., Johnson E., et al. Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons. Neuron 35 2 (2002) 267-282
96. Horne-Badovinac S., Lin D., Waldron S., Schwarz M., Mbamalu G., Pawson T., et al. Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis. Curr Biol 11 19 (2001) 1492-1502
97. Hu N., Sedmera D., Yost H.J., and Clark E.B. Structure and function of the developing zebrafish heart. Anat Rec 260 2 (2000) 148-157
98. Hu N., Yost H.J., and Clark E.B. Cardiac morphology and blood pressure in the adult zebrafish. Anat Rec 264 1 (2001) 1-12
99. Huang H., Zhang B., Hartenstein P.A., Chen J.N., and Lin S. NXT2 is required for embryonic heart development in zebrafish. BMC Dev Biol 5 (2005) 7
100. Isogai S., Horiguchi M., and Weinstein B.M. The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev Biol 230 2 (2001) 278-301
101. Isogai S., Lawson N.D., Torrealday S., Horiguchi M., and Weinstein B.M. Angiogenic network formation in the developing vertebrate trunk. Development 130 21 (2003) 5281-5290
102. Itoh M., Kim C.H., Palardy G., Oda T., Jiang Y.J., Maust D., et al. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev Cell 4 1 (2003) 67-82
103. Jain R.K. Molecular regulation of vessel maturation. Nat Med 9 6 (2003) 685-693
104. Jaiswal J.K., Mattoussi H., Mauro J.M., and Simon S.M. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat Biotechnol 21 1 (2003) 47-51
105. Jaiswal J.K., Goldman E.R., Mattoussi H., and Simon S.M. Use of quantum dots for live cell imaging. Nat Methods 1 1 (2004) 73-78
106. Jekosch K. The zebrafish genome project: sequence analysis and annotation. Methods Cell Biol 77 (2004) 225-239
107. Jiang B., Liou G.I., Behzadian M.A., and Caldwell R.B. Astrocytes modulate retinal vasculogenesis: effects on fibronectin expression. J Cell Sci 107 Pt 9 (1994) 2499-2508
108. Jiang Y.J., Brand M., Heisenberg C.P., Beuchle D., Furutani-Seiki M., Kelsh R.N., et al. Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development 123 (1996) 205-216
109. Jin S.W., Beis D., Mitchell T., Chen J.N., and Stainier D.Y. Cellular and molecular analyses of vascular tube and lumen formation in zebrafish. Development 132 23 (2005) 5199-5209
110. Jin S.W., Herzog W., Santoro M.M., Mitchell T.S., Frantsve J., Jungblut B., et al. A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Developmental Biology 307 1 (2007) 29-42
111. Jones C.A., and Li D.Y. Common cues regulate neural and vascular patterning. Curr Opin Genet Dev 17 4 (2007) 332-336
112. Kallianpur A.R., Jordan J.E., and Brandt S.J. The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood 83 5 (1994) 1200-1208
113. Kamei M., Saunders W.B., Bayless K.J., Dye L., Davis G.E., and Weinstein B.M. Endothelial tubes assemble from intracellular vacuoles in vivo. Nature 442 7101 (2006) 453-456
114. Kari G., Rodeck U., and Dicker A.P. Zebrafish: an emerging model system for human disease and drug discovery. Clin Pharmacol Ther 82 1 (2007) 70-80
115. Karlstrom R.O., Talbot W.S., and Schier A.F. Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning. Genes Dev 13 4 (1999) 388-393
116. Kawakami K., and Hopkins N. Rapid identification of transgenic zebrafish. Trends Genet 12 1 (1996) 9-10
117. Kawakami A., Nojima Y., Toyoda A., Takahoko M., Satoh M., Tanaka H., et al. The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling. Curr Biol 15 5 (2005) 480-488
118. Keegan B.R., Feldman J.L., Lee D.H., Koos D.S., Ho R.K., Stainier D.Y., et al. The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo. Development 129 7 (2002) 1623-1632
119. Keller E.T., and Murtha J.M. The use of mature zebrafish (Danio rerio) as a model for human aging and disease. Comp Biochem Physiol C Toxicol Pharmacol 138 3 (2004) 335-341
120. Kelsh R.N., Brand M., Jiang Y.J., Heisenberg C.P., Lin S., Haffter P., et al. Zebrafish pigmentation mutations and the processes of neural crest development. Development 123 (1996) 369-389
121. Kidd K.R., and Weinstein B.M. Fishing for novel angiogenic therapies. Br J Pharmacol 140 4 (2003) 585-594
122. Kiener T.K., Sleptsova-Friedrich I., and Hunziker W. Identification, tissue distribution and developmental expression of tjp1/zo-1, tjp2/zo-2 and tjp3/zo-3 in the zebrafish, Danio rerio. Gene Expr Patterns 7 7 (2007) 767-776
123. Kikuchi Y., Trinh L.A., Reiter J.F., Alexander J., Yelon D., and Stainier D.Y. The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors. Genes Dev 14 10 (2000) 1279-1289
124. Kikuchi Y., Agathon A., Alexander J., Thisse C., Waldron S., Yelon D., et al. Casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafish. Genes Dev 15 12 (2001) 1493-1505
125. Kimmel C.B., Kane D.A., Walker C., Warga R.M., and Rothman M.B. A mutation that changes cell movement and cell fate in the zebrafish embryo. Nature 337 6205 (1989) 358-362
126. Klagsbrun M., and Eichmann A. A role for axon guidance receptors and ligands in blood vessel development and tumor angiogenesis. Cytokine Growth Factor Rev 16 4-5 (2005) 535-548
127. Knapik E.W. ENU mutagenesis in zebrafish-from genes to complex diseases. Mamm Genome 11 7 (2000) 511-519
128. Kopp R., Schwerte T., and Pelster B. Cardiac performance in the zebrafish breakdance mutant. J Exp Biol 208 Pt 11 (2005) 2123-2134
129. Krebs L.T., Xue Y., Norton C.R., Shutter J.R., Maguire M., Sundberg J.P., et al. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev 14 11 (2000) 1343-1352
130. Kuchler A.M., Gjini E., Peterson-Maduro J., Cancilla B., Wolburg H., and Schulte-Merker S. Development of the zebrafish lymphatic system requires VEGFC signaling. Curr Biol 16 12 (2006) 1244-1248
131. Kudoh T., Tsang M., Hukriede N.A., Chen X., Dedekian M., Clarke C.J., et al. A gene expression screen in zebrafish embryogenesis. Genome Res 11 12 (2001) 1979-1987
132. Kuruvilla R., Zweifel L.S., Glebova N.O., Lonze B.E., Valdez G., Ye H., et al. A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling. Cell 118 2 (2004) 243-255
133. Lam S.H., Wu Y.L., Vega V.B., Miller L.D., Spitsbergen J., Tong Y., et al. Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression. Nat Biotechnol 24 1 (2006) 73-75
134. Langenau D.M., Traver D., Ferrando A.A., Kutok J.L., Aster J.C., Kanki J.P., et al. Myc-induced T cell leukemia in transgenic zebrafish. Science 299 5608 (2003) 887-890
135. Langenbacher A.D., Dong Y., Shu X., Choi J., Nicoll D.A., Goldhaber J.I., et al. Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. Proc Natl Acad Sci U S A 102 49 (2005) 17699-17704
136. Larson D.R., Zipfel W.R., Williams R.M., Clark S.W., Bruchez M.P., Wise F.W., et al. Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science 300 5624 (2003) 1434-1436
137. Larson J.D., Wadman S.A., Chen E., Kerley L., Clark K.J., Eide M., et al. Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development. Dev Dyn 231 1 (2004) 204-213
138. Lawson N.D., and Weinstein B.M. Arteries and veins: making a difference with zebrafish. Nat Rev Genet 3 9 (2002) 674-682
139. Lawson N.D., and Weinstein B.M. In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev Biol 248 2 (2002) 307-318
140. Lawson N.D., Scheer N., Pham V.N., Kim C.H., Chitnis A.B., Campos-Ortega J.A., et al. Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128 19 (2001) 3675-3683
141. Lawson N.D., Vogel A.M., and Weinstein B.M. sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell 3 1 (2002) 127-136
142. Lawson N.D., Mugford J.W., Diamond B.A., and Weinstein B.M. phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev 17 11 (2003) 1346-1351
143. le Noble F., Moyon D., Pardanaud L., Yuan L., Djonov V., Matthijsen R., et al. Flow regulates arterial-venous differentiation in the chick embryo yolk sac. Development 131 2 (2004) 361-375
144. Lee R.K., Stainier D.Y., Weinstein B.M., and Fishman M.C. Cardiovascular development in the zebrafish. II. Endocardial progenitors are sequestered within the heart field. Development 120 12 (1994) 3361-3366
145. Lemmens R., Van Hoecke A., Hersmus N., Geelen V., D'Hollander I., Thijs V., et al. Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish. Hum Mol Genet 16 19 (2007) 2359-2365
146. Lepilina A., Coon A.N., Kikuchi K., Holdway J.E., Roberts R.W., Burns C.G., et al. A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. Cell 127 3 (2006) 607-619
147. Leslie J.D., Ariza-McNaughton L., Bermange A.L., McAdow R., Johnson S.L., and Lewis J. Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis. Development 134 5 (2007) 839-844
148. Liao W., Bisgrove B.W., Sawyer H., Hug B., Bell B., Peters K., et al. The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation. Development 124 2 (1997) 381-389
149. Liao E.C., Paw B.H., Oates A.C., Pratt S.J., Postlethwait J.H., and Zon L.I. SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes Dev 12 5 (1998) 621-626
150. Liao E.C., Paw B.H., Peters L.L., Zapata A., Pratt S.J., Do C.P., et al. Hereditary spherocytosis in zebrafish riesling illustrates evolution of erythroid beta-spectrin structure, and function in red cell morphogenesis and membrane stability. Development 127 23 (2000) 5123-5132
151. Liao W., Ho C.Y., Yan Y.L., Postlethwait J., and Stainier D.Y. Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. Development 127 20 (2000) 4303-4313
152. Liao E.C., Trede N.S., Ransom D., Zapata A., Kieran M., and Zon L.I. Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish. Development 129 3 (2002) 649-659
153. Lien C.L., Schebesta M., Makino S., Weber G.J., and Keating M.T. Gene expression analysis of zebrafish heart regeneration. PLoS Biol 4 8 (2006) e260
154. Lieschke G.J., and Currie P.D. Animal models of human disease: zebrafish swim into view. Nat Rev Genet 8 5 (2007) 353-367
155. Lin S. Transgenic zebrafish. Methods Mol Biol 136 (2000) 375-383
156. Lin S., Yang S., and Hopkins N. lacZ expression in germline transgenic zebrafish can be detected in living embryos. Dev Biol 161 1 (1994) 77-83
157. Lin X., Rinaldo L., Fazly A.F., and Xu X. Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis. Dev Biol 303 2 (2007) 536-548
158. Lindsley R.C., Gill J.G., Kyba M., Murphy T.L., and Murphy K.M. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development 133 19 (2006) 3787-3796
159. Liu W.Y., Wang Y., Sun Y.H., Wang Y.P., Chen S.P., and Zhu Z.Y. Efficient RNA interference in zebrafish embryos using siRNA synthesized with SP6 RNA polymerase. Dev Growth Differ 47 5 (2005) 323-331
160. Liu J., Fraser S.D., Faloon P.W., Rollins E.L., Vom Berg J., Starovic-Subota O., et al. A betaPix Pak2a signaling pathway regulates cerebral vascular stability in zebrafish. Proc Natl Acad Sci U S A 104 35 (2007) 13990-13995
161. Lo J., Lee S., Xu M., Liu F., Ruan H., Eun A., et al. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Genome Res 13 3 (2003) 455-466
162. Long Q., Meng A., Wang H., Jessen J.R., Farrell M.J., and Lin S. GATA-1 expression pattern can be recapitulated in living transgenic zebrafish using GFP reporter gene. Development 124 20 (1997) 4105-4111
163. Lowery L.A., Rubin J., and Sive H. Whitesnake/sfpq is required for cell survival and neuronal development in the zebrafish. Dev Dyn 236 5 (2007) 1347-1357
164. Lu X., Le Noble F., Yuan L., Jiang Q., De Lafarge B., Sugiyama D., et al. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 432 7014 (2004) 179-186
165. Lucini C., Maruccio L., Tafuri S., Staiano N., and Castaldo L. Artemin-like immunoreactivity in the zebrafish, Danio rerio. Anat Embryol (Berl) 208 5 (2004) 403-410
166. Luttun A., Carmeliet G., and Carmeliet P. Vascular progenitors: from biology to treatment. Trends Cardiovasc Med 12 2 (2002) 88-96
167. Lyons S.E., Lawson N.D., Lei L., Bennett P.E., Weinstein B.M., and Liu P.P. A nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes. Proc Natl Acad Sci U S A 99 8 (2002) 5454-5459
168. Mably J.D., Mohideen M.A., Burns C.G., Chen J.N., and Fishman M.C. heart of glass regulates the concentric growth of the heart in zebrafish. Curr Biol 13 24 (2003) 2138-2147
169. Mably J.D., Chuang L.P., Serluca F.C., Mohideen M.A., Chen J.N., and Fishman M.C. Santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish. Development 133 16 (2006) 3139-3146
170. Makinen T., Norrmen C., and Petrova T.V. Molecular mechanisms of lymphatic vascular development. Cell Mol Life Sci 64 15 (2007) 1915-1929
171. Malicki J., and Driever W. Oko meduzy mutations affect neuronal patterning in the zebrafish retina and reveal cell-cell interactions of the retinal neuroepithelial sheet. Development 126 6 (1999) 1235-1246
172. Malicki J., Neuhauss S.C., Schier A.F., Solnica-Krezel L., Stemple D.L., Stainier D.Y., et al. Mutations affecting development of the zebrafish retina. Development 123 (1996) 263-273
173. Malone M.H., Sciaky N., Stalheim L., Hahn K.M., Linney E., and Johnson G.L. Laser-scanning velocimetry: a confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae. BMC Biotechnol 7 (2007) 40
174. Martyn U., and Schulte-Merker S. Zebrafish neuropilins are differentially expressed and interact with vascular endothelial growth factor during embryonic vascular development. Dev Dyn 231 1 (2004) 33-42
175. Matsui T., Raya A., Callol-Massot C., Kawakami Y., Oishi I., Rodriguez-Esteban C., et al. Miles-apart-Mediated regulation of cell-fibronectin interaction and myocardial migration in zebrafish. Nat Clin Pract Cardiovasc Med 4 Suppl 1 (2007) S77-S82
176. McCallum C.M., Comai L., Greene E.A., and Henikoff S. Targeted screening for induced mutations. Nat Biotechnol 18 4 (2000) 455-457
177. Michalet X., Pinaud F.F., Bentolila L.A., Tsay J.M., Doose S., Li J.J., et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307 5709 (2005) 538-544
178. Mizuno H., Mal T.K., Tong K.I., Ando R., Furuta T., Ikura M., et al. Photo-induced peptide cleavage in the green-to-red conversion of a fluorescent protein. Mol Cell 12 4 (2003) 1051-1058
179. Motoike T., Loughna S., Perens E., Roman B.L., Liao W., Chau T.C., et al. Universal GFP reporter for the study of vascular development. Genesis 28 2 (2000) 75-81
180. Mukouyama Y.S., Shin D., Britsch S., Taniguchi M., and Anderson D.J. Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin. Cell 109 6 (2002) 693-705
181. Murayama E., Kissa K., Zapata A., Mordelet E., Briolat V., Lin H.F., et al. Tracing hematopoietic precursor migration to successive hematopoietic organs during zebrafish development. Immunity 25 6 (2006) 963-975
182. Nakano Y., Kim H.R., Kawakami A., Roy S., Schier A.F., and Ingham P.W. Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo. Dev Biol 269 2 (2004) 381-392
183. Nasevicius A., and Ekker S.C. Effective targeted gene 'knockdown' in zebrafish. Nat Genet 26 2 (2000) 216-220
184. Neuhauss S.C., Solnica-Krezel L., Schier A.F., Zwartkruis F., Stemple D.L., Malicki J., et al. Mutations affecting craniofacial development in zebrafish. Development 123 (1996) 357-367
185. Nicoli S., Ribatti D., Cotelli F., and Presta M. Mammalian tumor xenografts induce neovascularization in zebrafish embryos. Cancer Res 67 7 (2007) 2927-2931
186. Nilsson A.S., Fainzilber M., Falck P., and Ibanez C.F. Neurotrophin-7: a novel member of the neurotrophin family from the zebrafish. FEBS Lett 424 3 (1998) 285-290
187. Ober E.A., Olofsson B., Makinen T., Jin S.W., Shoji W., Koh G.Y., et al. Vegfc is required for vascular development and endoderm morphogenesis in zebrafish. EMBO Rep 5 1 (2004) 78-84
188. Omori Y., and Malicki J. oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo. Curr Biol 16 10 (2006) 945-957
189. Park K.W., Morrison C.M., Sorensen L.K., Jones C.A., Rao Y., Chien C.B., et al. Robo4 is a vascular-specific receptor that inhibits endothelial migration. Dev Biol 261 1 (2003) 251-267
190. Park K.W., Crouse D., Lee M., Karnik S.K., Sorensen L.K., Murphy K.J., et al. The axonal attractant Netrin-1 is an angiogenic factor. Proc Natl Acad Sci U S A 101 46 (2004) 16210-16215
191. Park K.W., Urness L.D., Senchuk M.M., Colvin C.J., Wythe J.D., Chien C.B., et al. Identification of new netrin family members in zebrafish: developmental expression of netrin 2 and netrin 4. Dev Dyn 234 3 (2005) 726-731
192. Park C., Lavine K., Mishina Y., Deng C.X., Ornitz D.M., and Choi K. Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development 133 17 (2006) 3473-3484
193. Patterson L.J., Gering M., and Patient R. Scl is required for dorsal aorta as well as blood formation in zebrafish embryos. Blood 105 9 (2005) 3502-3511
194. Patton E.E., Widlund H.R., Kutok J.L., Kopani K.R., Amatruda J.F., Murphey R.D., et al. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol 15 3 (2005) 249-254
195. Paw B.H. Cloning of the zebrafish retsina blood mutation: a genetic model for dyserythropoiesis and erythroid cytokinesis. Blood Cells Mol Dis 27 1 (2001) 62-64
196. Paw B.H., Davidson A.J., Zhou Y., Li R., Pratt S.J., Lee C., et al. Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nat Genet 34 1 (2003) 59-64
197. Pelster B., Sanger A.M., Siegele M., and Schwerte T. Influence of swim training on cardiac activity, tissue capillarization, and mitochondrial density in muscle tissue of zebrafish larvae. Am J Physiol Regul Integr Comp Physiol 285 2 (2003) R339-R347
198. Penberthy W.T., Shafizadeh E., and Lin S. The zebrafish as a model for human disease. Front Biosci 7 (2002) d1439-d1453
199. Peterson R.T., Link B.A., Dowling J.E., and Schreiber S.L. Small molecule developmental screens reveal the logic and timing of vertebrate development. Proc Natl Acad Sci U S A 97 24 (2000) 12965-12969
200. Peterson R.T., Mably J.D., Chen J.N., and Fishman M.C. Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Curr Biol 11 19 (2001) 1481-1491
201. Pham V.N., Lawson N.D., Mugford J.W., Dye L., Castranova D., Lo B., et al. Combinatorial function of ETS transcription factors in the developing vasculature. Dev Biol 303 2 (2007) 772-783
202. Piotrowski T., Schilling T.F., Brand M., Jiang Y.J., Heisenberg C.P., Beuchle D., et al. Jaw and branchial arch mutants in zebrafish II: anterior arches and cartilage differentiation. Development 123 (1996) 345-356
203. Piotrowski T., Ahn D.G., Schilling T.F., Nair S., Ruvinsky I., Geisler R., et al. The zebrafish van Gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development 130 20 (2003) 5043-5052
204. Poss K.D. Getting to the heart of regeneration in zebrafish. Semin Cell Dev Biol 18 1 (2007) 36-45
205. Poss K.D., Wilson L.G., and Keating M.T. Heart regeneration in zebrafish. Science 298 5601 (2002) 2188-2190
206. Poss K.D., Keating M.T., and Nechiporuk A. Tales of regeneration in zebrafish. Dev Dyn 226 2 (2003) 202-210
207. Potente M., Ghaeni L., Baldessari D., Mostoslavsky R., Rossig L., Dequiedt F., et al. SIRT1 controls endothelial angiogenic functions during vascular growth. Genes Dev 21 20 (2007) 2644-2658
208. Qian F., Zhen F., Ong C., Jin S.W., Meng Soo H., Stainier D.Y., et al. Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes. Dev Dyn 233 3 (2005) 1163-1172
209. Quiring R., Wittbrodt B., Henrich T., Ramialison M., Burgtorf C., Lehrach H., et al. Large-scale expression screening by automated whole-mount in situ hybridization. Mech Dev 121 7-8 (2004) 971-976
210. Ransom D.G., Haffter P., Odenthal J., Brownlie A., Vogelsang E., Kelsh R.N., et al. Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development 123 (1996) 311-319
211. Ransom D.G., Bahary N., Niss K., Traver D., Burns C., Trede N.S., et al. The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol 2 8 (2004) E237
212. Reiter J.F., Alexander J., Rodaway A., Yelon D., Patient R., Holder N., et al. Gata5 is required for the development of the heart and endoderm in zebrafish. Genes Dev 13 22 (1999) 2983-2995
213. Rhodes J.M., and Simons M. The extracellular matrix and blood vessel formation: not just a scaffold. J Cell Mol Med 11 2 (2007) 176-205
214. Rieger S., Kulkarni R.P., Darcy D., Fraser S.E., and Koster R.W. Quantum dots are powerful multipurpose vital labeling agents in zebrafish embryos. Dev Dyn 234 3 (2005) 670-681
215. Risau W. Differentiation of endothelium. Faseb J 9 10 (1995) 926-933
216. Risau W. Mechanisms of angiogenesis. Nature 386 6626 (1997) 671-674
217. Risau W., and Flamme I. Vasculogenesis. Annu Rev Cell Dev Biol 11 (1995) 73-91
218. Roman B.L., and Weinstein B.M. Building the vertebrate vasculature: research is going swimmingly. Bioessays 22 10 (2000) 882-893
219. Roman B.L., Pham V.N., Lawson N.D., Kulik M., Childs S., Lekven A.C., et al. Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development 129 12 (2002) 3009-3019
220. Rossant J., and Howard L. Signaling pathways in vascular development. Annu Rev Cell Dev Biol 18 (2002) 541-573
221. Rottbauer W., Baker K., Wo Z.G., Mohideen M.A., Cantiello H.F., and Fishman M.C. Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel alpha1 subunit. Dev Cell 1 2 (2001) 265-275
222. Rottbauer W., Wessels G., Dahme T., Just S., Trano N., Hassel D., et al. Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart. Circ Res 99 3 (2006) 323-331
223. Santoro M.M., Samuel T., Mitchell T., Reed J.C., and Stainier D.Y. Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis. Nat Genet 39 11 (2007) 1397-1402 (Nov)
224. Sato T., and Mishina M. Representational difference analysis, high-resolution physical mapping, and transcript identification of the zebrafish genomic region for a motor behavior. Genomics 82 2 (2003) 218-229
225. Sato T., Takahoko M., and Okamoto H. HuC:Kaede, a useful tool to label neural morphologies in networks in vivo. Genesis 44 3 (2006) 136-142
226. Schauerte H.E., van Eeden F.J., Fricke C., Odenthal J., Strahle U., and Haffter P. Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish. Development 125 15 (1998) 2983-2993
227. Schier A.F., Neuhauss S.C., Harvey M., Malicki J., Solnica-Krezel L., Stainier D.Y., et al. Mutations affecting the development of the embryonic zebrafish brain. Development 123 (1996) 165-178
228. Schoenebeck J.J., Keegan B.R., and Yelon D. Vessel and blood specification override cardiac potential in anterior mesoderm. Dev Cell 13 2 (2007) 254-267
229. Schwerte T., and Fritsche R. Understanding cardiovascular physiology in zebrafish and Xenopus larvae: the use of microtechniques. Comp Biochem Physiol A Mol Integr Physiol 135 1 (2003) 131-145
230. Schwerte T., Uberbacher D., and Pelster B. Non-invasive imaging of blood cell concentration and blood distribution in zebrafish Danio rerio incubated in hypoxic conditions in vivo. J Exp Biol 206 Pt 8 (2003) 1299-1307
231. Sehnert A.J., Huq A., Weinstein B.M., Walker C., Fishman M., and Stainier D.Y. Cardiac troponin T is essential in sarcomere assembly and cardiac contractility. Nat Genet 31 1 (2002) 106-110
232. Shafizadeh E., Huang H., and Lin S. Transgenic zebrafish expressing green fluorescent protein. Methods Mol Biol 183 (2002) 225-233
233. Shafizadeh E., Paw B.H., Foott H., Liao E.C., Barut B.A., Cope J.J., et al. Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency. Development 129 18 (2002) 4359-4370
234. Shaner N.C., Campbell R.E., Steinbach P.A., Giepmans B.N., Palmer A.E., and Tsien R.Y. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol 22 12 (2004) 1567-1572
235. Shaw G.C., Cope J.J., Li L., Corson K., Hersey C., Ackermann G.E., et al. Mitoferrin is essential for erythroid iron assimilation. Nature 440 7080 (2006) 96-100
236. Shawber C.J., and Kitajewski J. Notch function in the vasculature: insights from zebrafish, mouse and man. Bioessays 26 3 (2004) 225-234
237. Shepard J.L., Amatruda J.F., Stern H.M., Subramanian A., Finkelstein D., Ziai J., et al. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proc Natl Acad Sci U S A 102 37 (2005) 13194-13199
238. Shepard J.L., Amatruda J.F., Finkelstein D., Ziai J., Finley K.R., Stern H.M., et al. A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes Dev 21 1 (2007) 55-59
239. Shima D.T., and Mailhos C. Vascular developmental biology: getting nervous. Curr Opin Genet Dev 10 5 (2000) 536-542
240. Siekmann A.F., and Lawson N.D. Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature 445 7129 (2007) 781-784
241. Smolowitz R., Hanley J., and Richmond H. A three-year retrospective study of abdominal tumors in zebrafish maintained in an aquatic laboratory animal facility. Biol Bull 203 2 (2002) 265-266
242. Song H.D., Sun X.J., Deng M., Zhang G.W., Zhou Y., Wu X.Y., et al. Hematopoietic gene expression profile in zebrafish kidney marrow. Proc Natl Acad Sci U S A 101 46 (2004) 16240-16245
243. Song M., Yang H., Yao S., Ma F., Li Z., Deng Y., et al. A critical role of vascular endothelial growth factor D in zebrafish embryonic vasculogenesis and angiogenesis. Biochem Biophys Res Commun 357 4 (2007) 924-930
244. Sood R., English M.A., Jones M., Mullikin J., Wang D.M., Anderson M., et al. Methods for reverse genetic screening in zebrafish by resequencing and TILLING. Methods 39 3 (2006) 220-227
245. Spitsbergen J.M., and Kent M.L. The state of the art of the zebrafish model for toxicology and toxicologic pathology research - advantages and current limitations. Toxicol Pathol 31 Suppl (2003) 62-87
246. Spitsbergen J.M., Tsai H.W., Reddy A., Miller T., Arbogast D., Hendricks J.D., et al. Neoplasia in zebrafish (Danio rerio) treated with 7,12-dimethylbenz[a]anthracene by two exposure routes at different developmental stages. Toxicol Pathol 28 5 (2000) 705-715
247. Spitsbergen J.M., Tsai H.W., Reddy A., Miller T., Arbogast D., Hendricks J.D., et al. Neoplasia in zebrafish (Danio rerio) treated with N-methyl-N'-nitro-N-nitrosoguanidine by three exposure routes at different developmental stages. Toxicol Pathol 28 5 (2000) 716-725
248. Sprague J., Bayraktaroglu L., Clements D., Conlin T., Fashena D., Frazer K., et al. The zebrafish information network: the zebrafish model organism database. Nucleic Acids Res 34 (2006) D581-D585 (Database issue)
249. Stainier D.Y. Zebrafish genetics and vertebrate heart formation. Nat Rev Genet 2 1 (2001) 39-48
250. Stainier D.Y., Weinstein B.M., Detrich III H.W., Zon L.I., and Fishman M.C. Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. Development 121 10 (1995) 3141-3150
251. Stainier D.Y., Fouquet B., Chen J.N., Warren K.S., Weinstein B.M., Meiler S.E., et al. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development 123 (1996) 285-292
252. Stanton M.F. Diethylnitrosamine-induced hepatic degeneration and neoplasia in the aquarium fish, Brachydanio rerio. J Natl Cancer Inst 34 (1965) 117-130
253. Stemple D.L. TILLING - a high-throughput harvest for functional genomics. Nat Rev Genet 5 2 (2004) 145-150
254. Stern H.M., and Zon L.I. Cancer genetics and drug discovery in the zebrafish. Nat Rev Cancer 3 7 (2003) 533-539
255. Streisinger G., Walker C., Dower N., Knauber D., and Singer F. Production of clones of homozygous diploid zebra fish (Brachydanio rerio). Nature 291 5813 (1981) 293-296
256. Stringer S.E. The role of heparan sulphate proteoglycans in angiogenesis. Biochem Soc Trans 34 Pt 3 (2006) 451-453
257. Stuart G.W., McMurray J.V., and Westerfield M. Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos. Development 103 2 (1988) 403-412
258. Stuart G.W., Vielkind J.R., McMurray J.V., and Westerfield M. Stable lines of transgenic zebrafish exhibit reproducible patterns of transgene expression. Development 109 3 (1990) 577-584
259. Sumanas S., and Lin S. Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol 4 1 (2006) e10
260. Sumanas S., Jorniak T., and Lin S. Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood 106 2 (2005) 534-541
261. Summerton J., and Weller D. Morpholino antisense oligomers: design, preparation, and properties. Antisense Nucleic Acid Drug Dev 7 3 (1997) 187-195
262. Talbot W.S., and Schier A.F. Positional cloning of mutated zebrafish genes. Methods Cell Biol 60 (1999) 259-286
263. Tang J., Hu G., Hanai J., Yadlapalli G., Lin Y., Zhang B., et al. A critical role for calponin 2 in vascular development. J Biol Chem 281 10 (2006) 6664-6672
264. Thisse B., Heyer V., Lux A., Alunni V., Degrave A., Seiliez I., et al. Spatial and temporal expression of the zebrafish genome by large-scale in situ hybridization screening. Methods Cell Biol 77 (2004) 505-519
265. Thompson M.A., Ransom D.G., Pratt S.J., MacLennan H., Kieran M.W., Detrich III H.W., et al. The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. Dev Biol 197 2 (1998) 248-269
266. Tjwa M., Luttun A., Autiero M., and Carmeliet P. VEGF and PlGF: two pleiotropic growth factors with distinct roles in development and homeostasis. Cell Tissue Res 314 1 (2003) 5-14
267. Torres-Vazquez J., Kamei M., and Weinstein B.M. Molecular distinction between arteries and veins. Cell Tissue Res 314 1 (2003) 43-59
268. Torres-Vazquez J., Gitler A.D., Fraser S.D., Berk J.D., Van N.P., Fishman M.C., et al. Semaphorin-plexin signaling guides patterning of the developing vasculature. Dev Cell 7 1 (2004) 117-123
269. Towbin J.A., and McQuinn T.C. Gridlock: a model for coarctation of the aorta?. Nat Med 1 11 (1995) 1141-1142
270. Traver D., Paw B.H., Poss K.D., Penberthy W.T., Lin S., and Zon L.I. Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol 4 12 (2003) 1238-1246
271. Tseng S.H., Lin S.M., Chen J.C., Su Y.H., Huang H.Y., Chen C.K., et al. Resveratrol suppresses the angiogenesis and tumor growth of gliomas in rats. Clin Cancer Res 10 6 (2004) 2190-2202
272. Udvadia A.J., and Linney E. Windows into development: historic, current, and future perspectives on transgenic zebrafish. Dev Biol 256 1 (2003) 1-17
273. van Eeden F.J., Granato M., Schach U., Brand M., Furutani-Seiki M., Haffter P., et al. Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 123 (1996) 153-164
274. Velazquez O.C. Angiogenesis and vasculogenesis: inducing the growth of new blood vessels and wound healing by stimulation of bone marrow-derived progenitor cell mobilization and homing. J Vasc Surg 45 Suppl A (2007) A39-A47
275. Visvader J.E., Fujiwara Y., and Orkin S.H. Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development. Genes Dev 12 4 (1998) 473-479
276. Vogeli K.M., Jin S.W., Martin G.R., and Stainier D.Y. A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula. Nature 443 7109 (2006) 337-339
277. Vokes S.A., and Krieg P.A. Endoderm is required for vascular endothelial tube formation, but not for angioblast specification. Development 129 3 (2002) 775-785
278. Vokes S.A., Yatskievych T.A., Heimark R.L., McMahon J., McMahon A.P., Antin P.B., et al. Hedgehog signaling is essential for endothelial tube formation during vasculogenesis. Development 131 17 (2004) 4371-4380
279. Voura E.B., Jaiswal J.K., Mattoussi H., and Simon S.M. Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat Med 10 9 (2004) 993-998
280. Walker C., and Streisinger G. Induction of mutations by gamma-rays in pregonial germ cells of zebrafish embryos. Genetics 103 1 (1983) 125-136
281. Walsh E.C., and Stainier D.Y. UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish. Science 293 5535 (2001) 1670-1673
282. Walter R.B., and Kazianis S. Xiphophorus interspecies hybrids as genetic models of induced neoplasia. Ilar J 42 4 (2001) 299-321
283. Wan H., He J., Ju B., Yan T., Lam T.J., and Gong Z. Generation of two-color transgenic zebrafish using the green and red fluorescent protein reporter genes gfp and rfp. Mar Biotechnol (NY) 4 2 (2002) 146-154
284. Wang D., Jao L.E., Zheng N., Dolan K., Ivey J., Zonies S., et al. Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proc Natl Acad Sci U S A 104 30 (2007) 12428-12433
285. Wang H., Long Q., Marty S.D., Sassa S., and Lin S. A zebrafish model for hepatoerythropoietic porphyria. Nat Genet 20 3 (1998) 239-243
286. Wang H., Charles P.C., Wu Y., Ren R., Pi X., Moser M., et al. Gene expression profile signatures indicate a role for Wnt signaling in endothelial commitment from embryonic stem cells. Circ Res 98 10 (2006) 1331-1339
287. Ward A.C., and Lieschke G.J. The zebrafish as a model system for human disease. Front Biosci 7 (2002) d827-d833
288. Warren K.S., Baker K., and Fishman M.C. The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish. Am J Physiol Heart Circ Physiol 281 4 (2001) H1711-H1719
289. Weber G.J., Choe S.E., Dooley K.A., Paffett-Lugassy N.N., Zhou Y., and Zon L.I. Mutant-specific gene programs in the zebrafish. Blood 106 2 (2005) 521-530
290. Weinstein B.M. What guides early embryonic blood vessel formation?. Dev Dyn 215 1 (1999) 2-11
291. Weinstein B.M., Stemple D.L., Driever W., and Fishman M.C. Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat Med 1 11 (1995) 1143-1147
292. Weinstein B.M., Schier A.F., Abdelilah S., Malicki J., Solnica-Krezel L., Stemple D.L., et al. Hematopoietic mutations in the zebrafish. Development 123 (1996) 303-309
293. Westerfield M., Wegner J., Jegalian B.G., DeRobertis E.M., and Puschel A.W. Specific activation of mammalian Hox promoters in mosaic transgenic zebrafish. Genes Dev 6 4 (1992) 591-598
294. Whitfield T.T., Granato M., van Eeden F.J., Schach U., Brand M., Furutani-Seiki M., et al. Mutations affecting development of the zebrafish inner ear and lateral line. Development 123 (1996) 241-254
295. Wiedmann B., Sakai H., Davis T.A., and Wiedmann M. A protein complex required for signal-sequence-specific sorting and translocation. Nature 370 6489 (1994) 434-440
296. Wienholds E., and Plasterk R.H. Target-selected gene inactivation in zebrafish. Methods Cell Biol 77 (2004) 69-90
297. Wienholds E., Schulte-Merker S., Walderich B., and Plasterk R.H. Target-selected inactivation of the zebrafish rag1 gene. Science 297 5578 (2002) 99-102
298. Wienholds E., van Eeden F., Kosters M., Mudde J., Plasterk R.H., and Cuppen E. Efficient target-selected mutagenesis in zebrafish. Genome Res 13 12 (2003) 2700-2707
299. Wijelath E.S., Murray J., Rahman S., Patel Y., Ishida A., Strand K., et al. Novel vascular endothelial growth factor binding domains of fibronectin enhance vascular endothelial growth factor biological activity. Circ Res 91 1 (2002) 25-31
300. Williams J.A., Barrios A., Gatchalian C., Rubin L., Wilson S.W., and Holder N. Programmed cell death in zebrafish rohon beard neurons is influenced by TrkC1/NT-3 signaling. Dev Biol 226 2 (2000) 220-230
301. Wilson B.D., Ii M., Park K.W., Suli A., Sorensen L.K., Larrieu-Lahargue F., et al. Netrins promote developmental and therapeutic angiogenesis. Science 313 5787 (2006) 640-644
302. Wingert R.A., Brownlie A., Galloway J.L., Dooley K., Fraenkel P., Axe J.L., et al. The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development 131 24 (2004) 6225-6235
303. Wright G.J., Leslie J.D., Ariza-McNaughton L., and Lewis J. Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development. Development 131 22 (2004) 5659-5669
304. Xu X., Meiler S.E., Zhong T.P., Mohideen M., Crossley D.A., Burggren W.W., et al. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nat Genet 30 2 (2002) 205-209
305. Yaniv K., Isogai S., Castranova D., Dye L., Hitomi J., and Weinstein B.M. Live imaging of lymphatic development in the zebrafish. Nat Med 12 6 (2006) 711-716
306. Yelon D., Ticho B., Halpern M.E., Ruvinsky I., Ho R.K., Silver L.M., et al. The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin development. Development 127 12 (2000) 2573-2582
307. You L.R., Lin F.J., Lee C.T., DeMayo F.J., Tsai M.J., and Tsai S.Y. Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature 435 7038 (2005) 98-104
308. Yu H.H., and Moens C.B. Semaphorin signaling guides cranial neural crest cell migration in zebrafish. Dev Biol 280 2 (2005) 373-385
309. Yutzey K.E., and Kirby M.L. Wherefore heart thou? Embryonic origins of cardiogenic mesoderm. Dev Dyn 223 3 (2002) 307-320
310. Zhang C., Li Q., Lim C.H., Qiu X., and Jiang Y.J. The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly. Dev Biol 305 1 (2007) 14-27
311. Zhong T.P., Rosenberg M., Mohideen M.A., Weinstein B., and Fishman M.C. Gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science 287 5459 (2000) 1820-1824
312. Zhong T.P., Childs S., Leu J.P., and Fishman M.C. Gridlock signalling pathway fashions the first embryonic artery. Nature 414 6860 (2001) 216-220
313. Zhong H., Wu X., Huang H., Fan Q., Zhu Z., and Lin S. Vertebrate MAX-1 is required for vascular patterning in zebrafish. Proc Natl Acad Sci U S A 103 45 (2006) 16800-16805
314. Zon L.I. Zebrafish: a new model for human disease. Genome Res 9 2 (1999) 99-100
315. Zon L.I., and Peterson R.T. In vivo drug discovery in the zebrafish. Nat Rev Drug Discov 4 1 (2005) 35-44