The bHLH transcription factor Hand2 plays parallel roles in zebrafish heart and pectoral fin development

Development

Volumn 127, Issue 12, 2000, Pages 2573-2582

  Yelon, Deborah ^a,e   Ticho, Baruch ^b   Halpern, Marnie E ^c   Ruvinsky, Ilya ^d   Ho, Robert K ^d   Silver, Lee M ^d   Stainier, Didier Y R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c GEOPHYSICAL LABORATORY   (United States)

^d PRINCETON UNIVERSITY   (United States)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Forelimb; Hands off; Lateral plate mesoderm; Sonic hedgehog; Tbx5; Zebrafish

Indexed keywords

TRANSCRIPTION FACTOR;

ARTICLE; CELL DIFFERENTIATION; EMBRYO; FORELIMB; GASTRULATION; HEART DEVELOPMENT; HEART MUSCLE; MESENCHYME; MESODERM; MORPHOGENESIS; NONHUMAN; PRECURSOR; PRIORITY JOURNAL; ZEBRA FISH;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; GENE LIBRARY; HEART; HEART DEFECTS, CONGENITAL; HELIX-LOOP-HELIX MOTIFS; MESODERM; MORPHOGENESIS; MUTAGENESIS; SKIN; TRANSCRIPTION FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 0033947661     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Akimenko, M.-A., Ekker, M., Wegner, J., Lin, W. and Westerfield, M. (1994). Combinatorial expression of three zebrafish genes related to Distalless: part of a homeobox gene code for the head. J. Neurosci. 14, 3475-3486.
2. Alexander, J., Stainier, D. Y. and Yelon, D. (1998). Screening mosaic F1 females for mutations affecting zebrafish heart induction and patterning. Dev. Genet. 22. 288-299.
3. Amemiya, C. T. and Zon, L. I. (1999). Generation of a zebrafish P1 artificial chromosome library. Genomics 58, 211-213.
4. Angelo, S., Lohr, J., Lee, K.H., Ticho, B., Breitbart, R., Hill, S., Yost, H.J. and Srivastava, D. (2000). Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch, and lateral mesoderm development. Mech. Dev. In press.
5. Bader, D., Masaki, T. and Fischman, D. A. (1982) Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J. Cell Biol. 95, 763-770.
6. Bao, Z. Z., Bruneau, B. G., Seidman, J. G., Seidman, C. E. and Cepko, C. L. (1999). Regulation of chamber-specific gene expression in the developing heart by Irx4. Science 283, 1161-1164.
7. Basson, C. T., Bachinsky, D. R., Lin, R. C., Levi, T., Elkins, J. A., Soults, J., Grayzel, D., Kroumpouzou, E., Traill, T. A., Leblanc-Straceski, J. et al. (1997). Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome. Nat. Genet. 15, 30-35.
8. Begemann, G. and Ingham, P. W. (2000). Developmental regulation of Tbx5 in zebrafish embryogenesis. Mech. Dev. 90, 299-304.
9. Biben, C. and Harvey, R. P. (1997). Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development. Genes Dev. 11, 1357-1369.
10. Bruneau, B. G., Bao, Z.-Z., Tanaka, M., Schott, J.-J., Izumo, S., Cepko, C. L., Seidman, J. G. and Seidman, C. E. (2000). Cardiac expression of the ventricle-specific homeobox gene lrx4 is modulated by Nkx2-5 and dHand. Dev. Biol. 217, 266-277.
11. Chazaud, C., Chambon, P. and Dollé, P. (1999). Retinoic acid is required in the mouse embryo for left-right asymmetry determination and heart morphogenesis. Development 126, 2589-2596.
12. Chen, J.-N. and Fishman, M. C. (1996). Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 122, 3809-3816.
13. Chen, J.-N., Haffter, P., Odenthal, J., Vogelsang, E., Brand, M., van Eeden, F. J., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C. P. et al. (1996). Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development 123, 293-302.
14. Cross, J. C., Flannery, M. L., Blanar, M. A., Steingrimsson, E., Jenkins, N. A., Copeland, N. G., Rutter, W. J. and Werb, Z. (1995). Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development. Development 121, 2513-2523.
15. Cserjesi, P., Brown, D., Lyons, G. E. and Olson, E. N. (1995). Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development. Dev. Biol. 170, 664-678.
16. Firulli, A. B., McFadden, D. G., Lin, Q., Srivastava, D. and Olson, E. N. (1998). Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Handl. Nat. Genet. 18, 266-270.
17. Geisler, R., Rauch, G. J., Baier, H., van Bebber, F., Brobeta, L., Dekens, M. P., Finger, K., Fricke, C., Gates, M. A., Geiger, H. et al. (1999). A radiation hybrid map of the zebrafish genome. Nat. Genet. 23, 86-89.
18. Gibson-Brown, J., Agulnik, S. I., Silver, L. M., Niswander, L. and Papaioannou, V. E. (1998). Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development. Development 125, 2499-2509.
19. Goldstein, A. M. and Fishman, M. C. (1998). Notochord regulates cardiac-lineage in zebrafish embryos. Dev. Biol. 201, 247-252.
20. Grandel, H. and Schulte-Merker, S. (1998). The development of the paired fins in the Zebrafish (Danio rerio). Mech. Dev. 79, 99-120.
21. Griffin, K. J. P., Stoller, J., Gibson, M., Chen, S., Yelon, D., Stainier, D. Y. R. and Kimelman, D. (2000). A conserved role for H15-related T-box transcription factors in zebrafish and Drosophila heart formation. Dev. Biol. 218, 235-247.
22. Hollenberg, S. M., Sternglanz, R., Cheng, P. F. and Weintraub, H. (1995). Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell. Biol. 15, 3813-3822.
23. Horb, M. E. and Thomsen, G. H. (1999). Tbx5 is essential for heart development. Development 126, 1739-1751.
24. Imai, Y., Feldman, B., Schier, A. F., and Talbot, W. S. (2000). Analysis of chromosomal rearrangements induced by postmeiotic mutagenesis with ethylnitrosourea in zebrafish. Genetics. In press.
25. Isaac, A., Rodriguez-Esteban, C., Ryan, A., Altabef, M., Tsukui, T., Patel, K., Tickle, C. and Izpisua-Belmonte, J. C. (1998). Tbx genes and limb identity in chick embryo development. Development 125, 1867-1875.
26. Johnson, R. L. and Tabin, C. J. (1997). Molecular models for vertebrate limb development. Cell 90, 979-990.
27. Johnson, S. L., Africa, D., Horne, S. and Postlethwait, J. H. (1995). Halftetrad analysis in zebrafish: mapping the ros mutation and the centromere of linkage group I. Genetics 139, 1727-1735.
28. Kishimoto, Y., Lee, K. H., Zon, L., Hammerschmidt, M. and Schulte-Merker, S. (1997). The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning. Development 124, 4457-4466.
29. Lee, K. H., Xu, Q. and Breitbart, R. E. (1996). A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm. Dev. Biol. 180, 722-731.
30. Li, Q. Y., Newbury-Ecob, R. A., Terrett, J. A., Wilson, D. I., Curtis, A. R., Yi, C. H., Gebuhr, T., Bullen, P. J., Robson, S. C., Strachan, T. et al. (1997). Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nat. Genet. 15, 21-29.
31. Logan, M., Simon, H.-G. and Tabin, C. (1998). Differential regulation of T-box and homeobox transcription factors suggests roles in controlling chick limb-type identity. Development 125, 2825-2835.
32. Martin, G. R. (1998). The roles of FGFs in the early development of vertebrate limbs. Genes Dev. 12, 1571-1586.
33. Neumann, C. J., Grandel, H., Gaffield, W., Schulte-Merker, S. and Nüsslein-Volhard, C. (1999). Transient establishment of anteroposterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity. Development 126, 4817-4826.
34. Niederreither, K., Subbarayan, V., Dolle, P. and Chambon, P. (1999). Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat. Genet. 21, 444-448.
35. Ohuchi, H., Takeuchi, J., oshioka, H., Ishimaru, Y., Ogura, K., Takahashi, N., Ogura, T. and Noji, S. (1998). Correlation of wing-leg identity in ectopic FGF-induced chimeric limbs with the differential expression of chick Tbx5 and Tbx4. Development 125, 51-60.
36. Reifers, F., Walsh, E. C., Léger, S., Stainier, D. Y. R. and Brand, M. (2000) Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar). Development 127, 225-235.
37. Reiter, J. F., Alexander, J., Rodaway, A., Yelon, D., Patient, R., Holder, N. and Stainier, D. Y. R. (1999). Gata5 is required for the development of the heart and endoderm-derived organs in zebrafish. Genes Dev. 13, 2983-2995.
38. Riley, P., Anson-Cartwright, L. and Cross, J. C. (1998). The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis. Nat. Genet. 18, 271-275.
39. Ruvinsky, I., Oates, A. C., Silver, L. M. and Ho, R. K. (2000). The evolution of paired appendages in vertebrates: T-box genes in the zebrafish. Dev. Genes Evol. 210, 82-91.
40. Schauerte, H. E., van Eeden, F. J. M., Fricke, C., Odenthal, J., Strähle, U. and Haffter, P. (1998). Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish. Development 125, 2983-2993.
41. Schultheiss, T. M., Burch, J. B. and Lassar, A. B. (1997). A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev. 11, 451-462.
42. Serbedzija, G. N., Chen, J. N. and Fishman, M. C. (1998). Regulation in the heart field of zebrafish. Development 125, 1095-1101.
43. Srivastava, D. (1999). HAND proteins: molecular mediators of cardiac development and congenital heart disease. Trends Cardiovasc. Med. 9, 11-18.
44. Srivastava, D., Cserjesi, P. and Olson, E. N. (1995). A subclass of bHLH proteins required for cardiac morphogenesis. Science 270, 1995-1999.
45. Srivastava, D., Thomas, T., Lin, Q., Kirby, M. L., Brown, D. and Olson, E. N. (1997). Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat. Genet. 16, 154-160.
46. Stainier, D. Y. R. and Fishman, M. C. (1992). Patterning the zebrafish heart tube: acquisition of anteroposterior polarity. Dev. Biol. 153, 91-101.
47. Stainier, D. Y. R., Fouquet, B., Chen, J. N., Warren, K. S., Weinstein, B. M., Meiler, S. E., Mohideen, M. A., Neuhauss, S. C., Solnica-Krezel, L., Schier, A. F. et al. (1996). Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development 123, 285-292.
48. Streisinger, G., Singer, F., Walker, C., Knauber, D. and Dower, N. ( 1986). Segregation analyses and gene-centromere distances in zebrafish. Genetics 112, 311-319.
49. Tamura, K., Yonei-Tamura, S. and Izpisúa Belmonte, J. C. (1999). Differential expression of Tbx4 and Tbx5 in Zebrafish fin buds. Mech. Dev. 87, 181-184.
50. Westerfield, M. (1995). The Zebrafish Book. Eugene, OR: Univ. of Oregon Press.
51. Wilson, G. N. (1998). Correlated heart/limb anomalies in mendelian syndromes provide evidence for a cardiomelic developmental field. Am. J. Med. Genet. 76, 297-305.
52. Xavier-Neto, J., Neville, C. M., Shapiro, M. D., Houghton, L., Wang, G. F., Nikovits, W. J., Stockdale, F. E. and Rosenthal, N. (1999). A retinoic acid-inducible transgenic marker of sino-atrial development in the mouse heart. Development 126, 2677-2687.
53. Yamagishi, H., Garg, V., Matsuoka, R., Thomas, T. and Srivastava, D. (1999). A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects. Science 283, 1158-1161.
54. Yelon, D., Home, S. A. and Stainier, D. Y. (1999). Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish. Dev. Biol. 214, 23-37.
55. Yelon, D. and Stainier, D. Y. (1999). Patterning during organogenesis: genetic analysis of cardiac chamber formation. Semin. Cell Dev. Biol. 10, 93-98.