Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development

Genes and Development

Volumn 12, Issue 4, 1998, Pages 473-479

  Visvader, Jane E ^a   Fujiwara, Yuko ^b   Orkin, Stuart H ^b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b NONE

Author keywords

Hematopoiesis; SCL tal 1 gene; Tie 2 gene; Vascular development

Indexed keywords

PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHIMERA; CONTROLLED STUDY; ENDOTHELIUM CELL; HEMATOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; T CELL LEUKEMIA; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM; YOLK SAC;

EID: 0032520080     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.4.473     Document Type: Article

References (39)

1. Baldwin, H., H. Shen, H. Yan, H. DeLisser, A. Chung, C. Mickanin, T. Trask, N. Kirschbaum, P. Newman, S. Albelda et al. 1994. Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development 120: 2539-2553.
2. Baumhueter, S., N. Dybdal, C. Kyle, and L. Laskey. 1994. Globular vascular expression of murine CD34, a sialo mucin-like endothelial lingand for L-selectin. Blood 84: 2554-2565.
3. Begley, C., P. Aplan, S. Denning, B. Haynes, T. Waldmann, and I. Kirsch. 1989. The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif. Proc. Natl Acad. Sci. 86: 10128-10132.
4. Carmeliet, P., V. Ferreira, G. Breier, S. Pollefeyt, L. Kieckens, M. Gertsenstein, M. Fahrig, A. Vandenhoeck, K. Harpal, C. Eberhardt, C. Declercq, J. Pawling, L. Moons, D. Collen, W. Risau, and A. Nagy. 1996a. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380: 435-439.
5. Carmeliet, P., N. Mackman, L. Moons, T. Luther, P. Gressens, I. Van Vlaenderen, H. Demunck, M. Kasper, G. Breier, P. Evrard, M. Müller, W. Risau, T. Edgington, and D. Collen. 1996b. Role of tissue factor in embryonic blood vessel development. Nature 383: 73-75.
6. Chen, Q., J.-T. Cheng, L.-H. Tsai, N. Schneider, G. Buchanan, A. Carroll, W. Crist, B. Ozanne, M.J. Siciliano, and R. Baer. 1990. The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein. EMBO J. 9: 415-424.
7. Dumont, D., J.G. Gradwohl, G.-H. Fong, M. Puri, M. Gertsenstein, A. Auerbach, and M.L. Breitman. 1994. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes & Dev. 8: 1897-1909.
8. Ferrara, N., K. Carver-Moore, H. Chen, M. Dowd, L. Lu, K.S. O'Shea, L. Powell-Braxton, K.J. Hillan, and M. Moore. 1996. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380: 439-442.
9. Finger, L.R., J. Kagan, G. Christopher, J. Kurtzberg, M.S. Hershfield, P.C. Nowell, and C.M. Croce. 1989. Involvement of the TCL5 gene on human chromosome 1 in T cell leukemia and melanoma. Proc. Natl Acad. Sci. 86: 5039-5043.
10. Fong, G.-H., J. Rossant, M. Gertsenstein, and M.L. Breitman. 1995. Role of the Flt-receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376: 66-70.
11. Green, A.R., E. Salvaris, and C.G. Begley. 1991. Erythroid expression of the helix-loop-helix gene SCL. Oncogene 6: 475-479.
12. Green, A.R., T. Lints, J. Visvader, R. Harvey, and C.G. Begley. 1992. SCL is coexpressed with GATA-1 in haemopoietic cells but is also expressed in developing brain. Oncogene 7: 653-660.
13. Hogan, B., R. Beddington, F. Constantini, and E. Lacy. 1994. Manipulating the mouse embryo: A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
14. Hwang, L.-Y., M. Siegelman, L. Davis, N. Oppenheimer-Marks, and R. Baer. 1993. Expression of the TALI proto-oncogene in cultured endothelial cells and blood vessels of the spleen. Oncogene 8: 3043-3046.
15. Kallianpur, A.R., J.E. Jordan, and S.J. Brandt. 1994. The SCL/ TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood 83: 1200-1208.
16. Lindeman, G.J., A.W. Harris, M.L. Bath, R.N. Eisenman, and J.M. Adams. 1995. Overexpressed max is not oncogenic and attenuates myc-induced lymphoproliferation and lymphomagenesis in transgenic mice. Oncogene 10: 1013-1017.
17. Maltepe, E., J.V. Schmidt, D. Baunoch, C.A. Bradfield, and M.C. Simon. 1997. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386: 403-407.
18. McDevitt, M.A., Y. Fujiwara, R.A. Shivdasani, and S.H. Orkin. 1997. An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice. Proc. Natl Acad. Sci. 94: 7976-7981.
19. 13 deficiency. Science 275: 533-536.
20. Pardanoud, L., F. Yassine, and F. Dieterlen-Lievre. 1989. Relationship between vasculogenesis, angiogenesis, and haemopoiesis during avian ontogeny. Development 105: 473-485.
21. Porcher, C., W. Swat, K. Rockwell, Y. Fujiwara, F.W. Alt, and S.H. Orkin. 1996. The T cell leukemia oncoprotein SCL/ tal-1 is essential for development of all hematopoietic lineages. Cell 86: 47-57.
22. Puri, M.C., J. Rossant, K. Alitalo, A. Bernstein, and J. Partanen. 1995. The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J. 14: 5884-5891.
23. Risau, W. 1997. Mechanisms of angiogenesis. Nature 386: 671-674.
24. Robb, L., I. Lyons, R. Li, L. Hartley, F. Köntgen, R.P. Harvey, D. Metcalf, and C.G. Begley. 1995. Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene. Proc. Natl Acad. Sci. 92: 7075-7079.
25. Robb, L., N. Elwood, A.G. Elefanty, F. Köntgen, R. Li, D. Barnett, and C.G. Begley. 1996. The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse. EMBO J. 15: 4123-4129.
26. Sato, T.N., Y. Tozawa, U. Deutsch, K. Wolburg-Buchholz, Y. Fujiwara, M. Gendron-Maguire, T. Gridley, H. Wolburg, W. Risau, and Y. Qin. 1995. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376: 70-74.
27. Schlaeger, T.M., S. Bartunkova, J.A. Lawitts, G. Teichmann, W. Risau, U. Deutsch, and T.N. Sato. 1997. Uniform vascular-endothelial-cell-specific gene expression in both embyronic and adult transgenic mice. Proc. Natl. Acad. Sci. 94: 3058-3063.
28. Schlaeger, T.M., Y. Qin, Y. Fujiwara, J. Magram, and T.N. Sato. 1995. Vascular endothelial cell lineage-specific promoter in transgenic mice. Development 121: 1089-1098.
29. Shalaby, F., J. Rossant, T. Yamaguchi, M. Gertsenstein, X.-F. Wu, M. Breitman, and A.C. Schuch. 1995. Failure of blood-island formation and vasculogenesis in Flk-1 deficient mice. Nature 376: 62-66.
30. Shalaby, F., J. Ho, W.L. Stanford, K.-D. Fischer, A.C. Schuch, L. Schwartz, A. Bernstein, and J. Rossant. 1997. A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89: 981-990.
31. Shivdasani, R.A., and S.H. Orkin. 1996. The transcriptional control of hematopoiesis. Blood 87: 4025-4039.
32. Shivdasani, R.A., E.L. Mayer, and S.H. Orkin. 1995. Absence of blood formation in mice lacking the T cell leukaemia protein tal-1/SCL. Nature 373: 432-434.
33. Silver, L., and J. Palis. 1997. Initiation of murine embryonic erythropoiesis: A spatial analysis. Blood 89: 1154-1164.
34. Suri, C., P.F. Jones, S. Patan, S. Bartunkova, P.C. Maisonpierre, S. Davis, T.N. Sato, and G.D. Yancopoulos. 1996. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87: 1171-1180.
35. Vikkula, M., L.M. Boon, K.L. Carraway III, J.T. Calvert, A.J. Kiamonti, B. Goumnerov, K.A. Pasyk, D.A. Marchuk, M.L. Warman, L.C. Cantley, J.B. Mulliken, and B.R. Olsen. 1996. Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2. Cell 87: 1181-1190.
36. Visvader, J., C.G. Begley, and J.M. Adams. 1991. Differential expression of the LYL, SCL and E2A helix-loop-helix genes within the hemopoietic system. Oncogene 6: 187-194.
37. Wang, L.C., F. Kuo, Y. Fujiwara, D.G. Gilliland, T.R. Golub, and S.H Orkin. 1997. Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the ETs-related factor TEL. EMBO J. 16: 4374-4383.
38. - embryonic stem cells. Genes & Dev. 8: 1184-1197.
39. Zambrowicz, B.P., A. Imamoto, S. Fiering, L.A. Herzenberg, W.G. Kerr, and P. Soriano. 1997. Disruption of overlapping transcripts in the ROSA βgeo 26 gene trap strain leads to widespread expression of β-galactosidase in mouse embryos and hematopoietic cells. Proc. Natl Acad. Sci. 94: 3789-3794.