Zebrafish neuropilins are differentially expressed and interact with vascular endothelial growth factor during embryonic vascular development

Developmental Dynamics

Volumn 231, Issue 1, 2004, Pages 33-42

  Martyn, Ulrike ^a   Schulfe Merker, Stefan ^a,b  

^a Exelixis Deutschland GmbH   (Germany)

^b Exelixis Deutschland   (Germany)

Author keywords

Angiogenesis; Arteries; Expression pattern; Neuropilin; Vascular endothelial growth factor; Veins; Zebrafish

Indexed keywords

NEUROPILIN; NEUROPILIN 1; NEUROPILIN 2; PROTEIN TYROSINE KINASE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

BLOOD VESSEL; CONFERENCE PAPER; CONGENITAL BLOOD VESSEL MALFORMATION; CONGENITAL HEART MALFORMATION; EMBRYO; EMBRYO DEVELOPMENT; GENE; GENE FUNCTION; NONHUMAN; NRP1A GENE; NRP2A GENE; NRP2B GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; VERTEBRATE; ZEBRA FISH;

ANIMALS; BLOOD VESSELS; CARDIOVASCULAR ABNORMALITIES; EMBRYO, NONMAMMALIAN; IN SITU HYBRIDIZATION; NEUROPILINS; PHYLOGENY; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A; ZEBRAFISH;

DANIO RERIO; VERTEBRATA;

EID: 4143055723     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.20048     Document Type: Conference Paper

References (35)

1. Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declerq C, Pawling J, Moons L, Collen D, Risau W, Nagy A. 1996. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435-439.
2. Carmeliet P. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat Med 6:389-395.
3. Chen H, Chedotal A, He Z, Goodman CS, Tessier-Lavigne M. 1997. Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the Semaphorins Sema E and Sema IV but not Sema III. Neuron 19:547-559.
4. Childs S, Chen JN, Garrity DM, Fishman MC. 2002. Patterning of angiogenesis in the zebrafish embryo. Development 129:973-982.
5. Gluzman-Poltorak Z, Cohen T, Shibuya M, Neufeld G. 2001. Vascular endothelial growth factor receptor-1 and neuropilin-2 form complexes. J Biol Chem 276:18688-18694.
6. Habeck H, Odenthal J, Walderich B, Maischein H, Schulte-Merker S. 2002. Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Curr Biol 12:1405-1412.
7. Haffter P, Granato M, Brand M, Mullins MC, Hammerschmidt M, Kane DA, Odenthal J, van Eeden FJ, Jiang YJ, Heisenberg CP, Kelsh RN, Furutani-Seiki M, Vogelsang E, Beuchle D, Schach U, Fabian C, Nüsslein-Volhard C. 1996. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123:1-36.
8. He Z, Tessier-Lavigne M. 1997. Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90:739-751.
9. Herzog Y, Kalcheim C, Kahane N, Reshef R, Neufeld G. 2001. Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins. Mech Dev 109:115-119.
10. Kawakami A, Kitsukawa T, Takagi S, Fujisawa H. 1996. Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system. J Neurobiol 29:1-17.
11. Kawasaki T, Kitsukawa T, Bekku Y, Matsuda Y, Sanbo M, Yagi T, Fujisawa H. 1999. A requirement for neuropilin-1 in embryonic vessel formation. Development 126:4895-4902.
12. Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. 1995. Stages of embryonic development of the zebrafish. Dev Dyn 203:253-310.
13. Kitsukawa T, Shimono A, Kawakami A, Kondoh H, Fujisawa H. 1995. Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development 121:4309-4318.
14. Kitsukawa T, Shimizu M, Sanbo M, Hirata T, Taniguchi M, Bekku Y, Yagi T, Fujisawa H. 1997. Neuropilin-Semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron 19:995-1005.
15. Kolodkin AL, Levengood DV, Rowe EG, Tai YT, Giger RJ, Ginty DD. 1997. Neuropilin is a semaphorin III receptor. Cell 90:753-762.
16. Lawson ND, Scheer N, Pham VN, Kim CH, Chitnis AB, Campos-Ortega JA, Weinstein BM. 2001. Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128:3675-3683.
17. Lawson ND, Vogel AM, Weinstein BM. 2002. sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell 3:127-136.
18. Lee P, Goishi K, Davidson AJ, Mannix R, Zon L, Klagsbrun M. 2002. Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebraflsh. Proc Natl Acad Sci U S A 99:10470-10475.
19. Martyn U. 1999. Klonierung und Charakterisierung von Neuropilin im Zebrafisch (Danio rerio). Tübingen: Diplomarbeit.
20. Moyon D, Pardanaud L, Yuan L, Breant C, Eichmann A. 2001. Plasticity of endothelial cells during arterial-venous differentiation in the avian embryo. Development 128:3359-3370.
21. Mukouyama YS, Shin D, Britsch S, Taniguchi M, Anderson DJ. 2002. Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin. Cell 109:693-705.
22. Nasevicius A, Larson J, Ekker SC. 2000, Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast 17:294-301.
23. Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. 1999. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 13:9-22.
24. Neufeld G, Cohen T, Shraga N, Lange T, Kessler O, Herzog Y. 2002. The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis. Trends Cardiovasc Med 12:13-19.
25. Schulte-Merker S, Hammerschmidt M, Beuchle D, Cho KW, De Robertis EM, Nüsslein-Volhard C. 1994. Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos. Development 120:843-852.
26. Shoji W, Isogai S, Sato-Maeda M, Obinata M, Kuwada JY. 2003. Semaphorin3a1 regulates angioblast migration and vascular development in zebrafish embryos. Development 130:3227-3236.
27. Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. 1998. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92:735-745.
28. Stalmans I, Ng YS, Rohan R, Fruttiger M, Bouche A, Yuce A, Fujisawa H, Hermans B, Shani M, Jansen S, Hicklin D, Anderson DJ, Gardiner T, Hammes HP, Moons L, Dewerchin M, Collen D, Carmeliet P, D'Amore PA. 2002. Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest 109:327-336.
29. Takagi S, Hirata T, Agata K, Mochii M, Eguchi G, Fujisawa H. 1991. The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors. Neuron 7:295-307.
30. Takahashi T, Fournier A, Nakamura F, Wang LH, Murakami Y, Kalb RG, Fujisawa H, Strittmatter SM. 1999. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell 99:59-69.
31. Takashima S, Kitakaze M, Asakura M, Asanuma H, Sanada S, Tashiro F, Niwa H, Miyazaki JI, Hirota S, Kitamura Y, Kitsukawa T, Fujisawa H, Klagsbrun M, Hori M. 2002. Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci U S A 99:3657-3062.
32. Thompson MA, Ransom DG, Pratt SJ, MacLennan H, Kieran MW, Detrich HW III, Vail B, Huber TL, Paw B, Brownlie AJ, Oates AC, Fritz A, Gates MA, Amores A, Bahary N, Talbot WS, Her H, Beier DR, Postlethwait JH, Zon LI. 1998. The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. Dev Biol 197:248-269.
33. Visconti RP, Richardson CD, Sato TN. 2002. Orchestration of angiogenesis and arteriovenous contribution by angiopoietins and vascular endothelial growth factor (VEGF). Proc Natl Acad Sci U S A 99:8219-8224.
34. Weinstein BM, Stemple DL, Driever W, Fishman MC. 1995. Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat Med 1:1143-1147.
35. Yuan L, Moyon D, Pardanaud L, Breant C, Karkkainen MJ, Alitalo K, Eichmann A. 2002. Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development 129:4797-4806.