Sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation

Developmental Cell

Volumn 3, Issue 1, 2002, Pages 127-136

  Lawson, Nathan D ^a   Vogel, Andreas M ^a   Weinstein, Brant M ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; MESSENGER RNA; NOTCH RECEPTOR; SONIC HEDGEHOG PROTEIN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY ENDOTHELIUM; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; MARKER GENE; MICROINJECTION; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALIA; ERINACEIDAE;

EID: 0036070186     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(02)00198-3     Document Type: Article

References (50)

1. Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
2. Delta-mediated specification of midline cell fates in zebrafish embryos
3. Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos
4. Mutations affecting the cardiovascular system and other internal organs in zebrafish
5. Endoderm patterning by the notochord: Development of the hypochord in Xenopus
6. Teratogen-mediated inhibition of target tissue response to Shh signaling
7. Development of the hypochord and dorsal aorta in the zebrafish embryo (Danio rerio)
8. Vascular endothelial growth factor: Molecular and biological aspects
9. Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells
10. Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development
11. Two-color whole-mount in situ hybridization to vertebrate and Drosophila embryos
12. The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis
13. The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction
14. Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio
15. Comparative systeny cloning of zebrafish you-too: Mutations in the Hedgehog target gli2 affect ventral forebrain patterning
16. Stages of embryonic development of the zebrafish
17. Evolutionary analysis of vertebrate Notch genes
18. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos
19. Notch signaling is required for arterial-venous differentiation during embryonic vascular development
20. The role of vascular endothelial growth factor (VEGF) in vasculogenesis, angiogenesis, and hematopoiesis in zebrafish development
21. Cloning and characterization of vascular endothelial growth factor (VEGF) from zebrafish, Danio rerio
22. The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation
23. Plasticity of endothelial cells during arterial-venous differentiation in the avian embryo
24. Hedgehog signal transduction: From flies to vertebrates
25. Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling
26. Effective targeted gene 'knockdown' in zebrafish
27. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant
28. Transient establishment of anteroposterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity
29. Mutations affecting the formation of the notochord in the zebrafish, Danio rerio
30. The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors
31. The deltaA gene of zebrafish mediates lateral inhibition of hair cells in the inner ear and is regulated by pax2.1
32. The splice variants of vascular endothelial growth factor (VEGF) and their receptors
33. Xenopus embryos regulate the nuclear localization of XMyoD
34. Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish
35. Use of the Gal4-UAS technique for targeted gene expression in the zebrafish
36. An instructive function for Notch in promoting gliogenesis in the zebrafish retina
37. Mutations affecting the development of the embryonic zebrafish brain
38. Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization
39. Sequence and embryonic expression of deltaC in the zebrafish
40. General features, structure, topography, and adaptation of the circulatory system
41. The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis
42. Gridlock in the blood
43. Mutations affecting somite formation and patterning in the zebrafish, Danio rerio
44. Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels
45. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
46. Microinjection into zebrafish embryos
47. Gridlock signalling pathway fashions the first embryonic artery
48. Gridlock, an HLH gene required for assembly of the aorta in zebrafish