Heart regeneration in zebrafish

Science

Volumn 298, Issue 5601, 2002, Pages 2188-2190

  Poss, Kenneth D ^a   Wilson, Lindsay G ^a   Keating, Mark T ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CARDIOLOGY; CELLS; ENZYMES; HISTOLOGY; MUSCLE; MUTAGENESIS;

HEART REGENERATION;

GENETIC ENGINEERING;

PROTEIN; PROTEIN KINASE; PROTEIN MPS1; UNCLASSIFIED DRUG;

BIOLOGY; FISH; REGENERATION;

AMPHIBIA; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; HEART INJURY; HEART MUSCLE CELL; HISTOPATHOLOGY; MAMMAL; NONHUMAN; PRIORITY JOURNAL; SCAR; TISSUE REGENERATION; ZEBRA FISH;

ANIMALS; BLOOD COAGULATION; BROMODEOXYURIDINE; CELL DIVISION; COLLAGEN; FIBRIN; FIBROSIS; GENE EXPRESSION REGULATION; HEART; HEART INJURIES; HEART VENTRICLES; MITOSIS; MODELS, BIOLOGICAL; MUTATION; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; REGENERATION; TIME FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

AMPHIBIA; ANIMALIA; DANIO RERIO; MAMMALIA;

EID: 0037073890     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1077857     Document Type: Article

References (20)

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20. We thank A. Hillam for help with histology; A. Nechiporuk and S. Johnson for helping to generate and analyze mps1 mutants; H. Stern and R. Bronson for help with histopathology; D. Clapham for confocal imaging equipment; A. Nechiporuk, S. Odelherg, A. Limbourg, E. Lien, and L. Zon for critique of the manuscript; A. Sanchez and S. Kim for animal care; and Keating laboratory members for helpful discussions. Supported by the Helen Hay Whitney Foundation (K.D.P.) and grants from the National Heart, Lung, and Blood Institute. All animal procedures were performed in accordance with Children's Hospital guidelines.