Insertional Mutagenesis in Zebrafish

Developmental Dynamics

Volumn 228, Issue 3, 2003, Pages 523-534

  Amsterdam, Adam ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Functional genomics; Gene trap; Retrovirus; Vertebrate genetics; Zebrafish

Indexed keywords

GENE PRODUCT; MUTAGENIC AGENT;

ANIMAL TISSUE; CELL GROWTH; CELL VIABILITY; DNA FLANKING REGION; DNA INTEGRATION; EMBRYO DEVELOPMENT; GENE FUNCTION; GENE IDENTIFICATION; GENE INSERTION; GENE MUTATION; GENETIC SCREENING; GENOMICS; INSERTIONAL MUTAGENESIS; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; VERTEBRATE; ZEBRA FISH;

ANIMALS; DNA TRANSPOSABLE ELEMENTS; GENE EXPRESSION; MODELS, ANIMAL; MUTAGENESIS, INSERTIONAL; RETROVIRIDAE; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO; UNIDENTIFIED RETROVIRUS; VERTEBRATA;

EID: 0242474468     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.10381     Document Type: Review

References (59)

1. Allende ML, Amsterdam A, Becker T, Kawakami K, Galano N, Hopkins N. 1996. Insertional mutagenesis in zebrafish identifies two novel genes, pescadillo and dead eye, essential for embryonic development. Genes Dev 10: 3141-3155.
2. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. 1990. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402.
3. Amatruda JF, Shepard JL, Stern HM, Zon LI. 2002. Zebrafish as a cancer model system. Cancer Cell 1:229-231.
4. Amsterdam A, Burgess S, Golling G, Chen W, Sun Z, Townsend K, Farrington S, Haldi M, Hopkins N. 1999. A large-scale insertional mutagenesis screen in zebrafish. Genes Dev 13:2713-2724.
5. Barbacci E, Reber M, Ott MO, Breillat C, Huetz F, Cereghini S. 1999. Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification. Development 126:4795-4805.
6. Beattie CE, Raible DW, Henion PD, Eisen JS. 1999. Early pressure screens. Methods Cell Biol 60:71-86.
7. Burns JC, Friedmann T, Driever W, Burrascano M, Yee JK. 1993. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc Natl Acad Sci U S A 90: 8033-8037.
8. Chen W, Burgess S, Hopkins N. 2001. Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity. Development 128:2385-2396.
9. Chen W, Burgess S, Golling G, Amsterdam A, Hopkins N. 2002. High-throughput selection of retrovirus producer cell lines leads to markedly improved efficiency of germ line-transmissible insertions in zebra fish. J Virol 76:2192-2198.
10. Coffinier C, Thepot D, Babinet C, Yaniv M, Barra J. 1999. Essential role for the homeoprotein vHNF1/HNF1beta in visceral endoderm differentiation. Development 126:4785-4794.
11. Cooley L, Kelley R, Spradling A. 1988. Insertional mutagenesis of the Drosophila genome with single P elements. Science 239:1121-1128.
12. Driever W, Solnica-Krezel L, Schier AF, Neuhauss SC, Malicki J, Stemple DL, Stainier DY, Zwartkruis F, Abdelilah S, Rangini Z, Belak J, Boggs C. 1996. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 123:37-46.
13. Dupuy AJ, Fritz S, Largaespada DA. 2001. Transposition and gene disruption in the male germline of the mouse. Genesis 30:82-88.
14. Forrester LM, Nagy A, Sam M, Watt A, Stevenson L, Bernstein A, Joyner AL, Wurst W. 1996. An induction gene trap screen in embryonic stem cells: identification of genes that respond to retinoic acid in vitro. Proc Natl Acad Sci U S A 93:1677-1682.
15. FlyBase Consortium. 2002. The FlyBase database of the Drosophila genome projects and community literature. Nucleic Acids Res 30:106-108.
16. Galano N, Allende M, Amsterdam A, Kawakami K, Hopkins N. 1996a. Highly efficient germ-line transmission of proviral insertions in zebrafish. Proc Natl Acad Sci U S A 93:7777-7782.
17. Gaiano N, Amsterdam A, Kawakami K, Allende M, Becker T, Hopkins N. 1996b. Insertional mutagenesis and rapid cloning of essential genes in zebrafish. Nature 383:829-832.
18. Golling G, Amsterdam A, Sun Z, Antonelli M, Maldonado E, Chen W, Burgess S, Haldi M, Artzt K, Farrington S, Lin SY, Nissen RM, Hopkins N. 2002. Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nat Genet 31:135-140.
19. Gossler A, Joyner AL, Rossant J, Skarnes WC. 1989. Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes. Science 244:463-465.
20. Haffter P, Granato M, Brand M, Mullins MC, Hammerschmidt M, Kane DA, Odenthal J, van Eeden FJ, Jiang YJ, Heisenberg CP, Kelsh RN, Furutani-Seiki M, Vogelsang E, Beuchle D, Schach U, Fabian C, Nusslein-Volhard C. 1996. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123:1-36.
21. He L, Zhu Z, Faras AJ, Guise KS, Hackett PB, Kapuscinski AR. 1992. Characterization of Alul repeats of zebrafish (Brachydanio rerio). Mol Mar Biol Biotechnol 1:125-135.
22. Horikawa Y, Iwasaki N, Hara M, Furuta H, Hinokio Y, Cockburn BN, Lindner T, Yamagata K, Ogata M, Tomonaga O, Kuroki H, Kasahara T, Iwamoto Y, Bell GI. 1997. Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY. Nat Genet 17:384-385.
23. Ivics Z, Hackett PB, Plasterk RH, Izsvak Z. 1997. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 91:501-510.
24. Izsvak Z, Ivics Z, Garcia-Estefania D, Fahrenkrug SC, Hackett PB. 1996. DANA elements: a family of composite, tRNA-derived short interspersed DNA elements associated with mutational activities in zebrafish (Danio rerio). Proc Natl Acad Sci U S A 93:1077-1081.
25. Jacks T. 1996. Tumor suppressor gene mutations in mice, Annu Rev Genet 30:603-636.
26. Jaenisch R. 1988. Transgenic animals. Science 240:1468-1474.
27. Kane DA, Kimmel CB. 1993. The zebrafish midblastula transition. Development 119: 447-456.
28. Kawakami K, Amsterdam A, Shimoda N, Becker T, Mugg J, Shima A, Hopkins N. 2000a. Proviral insertions in the zebrafish hagoromo gene, encoding an F-box/WD40-repeat protein, cause stripe pattern anomalies. Curr Biol 10:463-466.
29. Kawakami K, Shima A, Kawakami N, 2000b. Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage. Proc Natl Acad Sci U S A 97:11403-11408.
30. Kimmel CB. 1989. Genetics and early development of zebrafish. Trends Genet 5:283-288.
31. Kimmel CB, Warga RM, Kane DA. 1994. Cell cycles and clonal strings during formation of the zebrafish central nervous system. Development 120:265-276.
32. Lee KY, Huang H, Ju B, Yang Z, Lin S. 2002. Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat Biotechnol 20:795-799.
33. Lin S, Gaiano N, Culp P, Burns JC, Friedmann T, Yee JK, Hopkins N. 1994. Integration and germ-line transmission of a pseudotyped retroviral vector in zebrafish. Science 265:666-669.
34. Mitchell KJ, Pinson KI, Kelly OG, Brennan J, Zupicich J, Scherz P, Leighton PA, Goodrich LV, Lu X, Avery BJ, Tate P, Dill K, Pangilinan E, Wakenight P, Tessier-Lavigne M, Skarnes WC. 2001. Functional analysis of secreted and transmembrane proteins critical to mouse development. Nat Genet 28:241-249.
35. Mooslehner K, Karls U, Harbers K. 1990. Retroviral integration sites in transgenic Mov mice frequently map in the vicinity of transcribed DNA regions. J Virol 64:3056-3058.
36. Mullins MC. 2002. Building-blocks of embryogenesis. Nat Genet 31:125-126.
37. Mullins MC, Hammerschmidt M, Haffter P, Nusslein-Volhard C. 1994. Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate. Curr Biol 4:189-202.
38. Nasevicius A, Ekker SC. 2000. Effective targeted gene 'knockdown' in zebrafish. Nat Genet 26:216-220.
39. Nishigori H, Yamada S, Kohama T, Tomura H, Sho K, Horikawa Y, Bell GI, Takeuchi T, Takeda J. 1998. Frameshift mutation, A263fsinsGG, in the hepatocyte nuclear factor-1beta gene associated with diabetes and renal dysfunction. Diabetes 47:1354-1355.
40. Nissen RM, Yan J, Amsterdam A, Hopkins N, Burgess SM. 2003. Zebrafish foxl one modulates cellular responses to Fgf signaling required for the integrity of ear and jaw patterning. Development 130: 2543-2554.
41. Raz E, van Luenen HG, Schaerringer B, Plasterk RH, Driever W. 1998. Transposition of the nematode Caenorhabditis elegans Tc3 element in the zebrafish Danio rerio. Curr Biol 8:82-88.
42. Riley BR, Grunwald DJ. 1995. Efficient induction of point mutations allowing recovery of specific locus mutations in zebrafish. Proc Natl Acad Sci U S A 92: 5997-6001.
43. Roberg-Perez K, Carlson CM, Largaespada DA. 2003. MTID: a database of Sleeping Beauty transposon insertions in mice. Nucleic Acids Res 31:78-81.
44. Scherdin U, Rhodes K, Breindl M. 1990. Transcriptionally active genome regions are preferred targets for retrovirus integration. J Virol 64:907-912.
45. Scherer CA, Chen J, Nachabeh A, Hopkins N, Ruley HE. 1996. Transcriptional specificity of the pluripotent embryonic stem cell. Cell Growth Differ 7:1393-1401.
46. Schlegel R, Tralka TS, Willingham MC, Pastan I. 1983. Inhibition of VSV binding and infectivity by phosphatidylserine: is phosphatidylserine a VSV-binding site? Cell 32:639-646.
47. Solnica-Krezel L, Schier AF, Driever W. 1994. Efficient recovery of ENU-induced mutations from the zebrafish germline. Genetics 136:1401-1420.
48. Spradling AC, Stern D, Beaton A, Rhem EJ, Laverty T, Mozden N, Misra S, Rubin GM. 1999. The Berkeley Drosophila Genome Project gene disruption project: single P-element insertions mutating 25% of vital Drosophila genes. Genetics 153:135-177.
49. Stanford WL, Cohn JB, Cordes SP. 2001. Gene-trap mutagenesis: past, present and beyond. Nat Rev Genet 2:756-768.
50. Stuart GW, McMurray JV, Westerfield M. 1988. Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos. Development 103:403-412.
51. Sun Z, Hopkins N. 2001. vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain. Genes Dev 15:3217-3229.
52. Walker C. 1999. Haploid screens and gamma-ray mutagenesis. Methods Cell Biol 60:43-70.
53. Wienholds E, Schulte-Merker S, Walderich B, Plasterk RH. 2002. Target-selected inactivation of the zebrafish ragl gene. Science 297:99-102.
54. Wiles MV, Vauti F, Otte J, Fuchtbauer EM, Ruiz P, Fuchtbauer A, Arnold HH, Lehrach H, Metz T, von Melchner H, Wurst W. 2000. Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat Genet 24:13-14.
55. Withers-Ward ES, Kitamura Y, Barnes JP, Coffin JM. 1994. Distribution of targets for avian retrovirus DNA integration in vivo. Genes Dev 8:1473-1487.
56. Wu X, Li Y, Crise B, Burgess SM. 2003. Transcription start regions in the human genome are favored targets for MLV integration. Science 300:1749-1751.
57. Yan YL, Miller CT, Nissen RM, Singer A, Liu D, Kirn A, Draper B, Willoughby J, Morcos PA, Amsterdam A, Chung BC, Westerfield M, Haffter P, Hopkins N, Kimmel C, Postlethwait JH, Nissen R, 2002. A zebrafish sox9 gene required for cartilage morphogenesis. Development 129:5065-5079.
58. Yoon C, Kawakami K, Hopkins N. 1997. Zebrafish vasa homologue RNA is localized to the cleavage planes of 2- and 4-cell-stage embryos and is expressed in the primordial germ cells. Development 124:3157-3165.
59. Zwaal RR, Broeks A, van Meurs J, Groenen JT, Plasterk RH. 1993. Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank. Proc Natl Acad Sci U S A 90:7431-7435.