How (and why) to revive a dead enzyme: The power of chemical rescue

Current Chemical Biology

Volumn 2, Issue 1, 2008, Pages 32-49

  Peracchi, Alessio ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Catalysis; Glycosidase; Pyridoxal 5' phosphate; Ribozyme; Transition state structure

Indexed keywords

ASPARTATE AMINOTRANSFERASE; ENZYME; GLYCOGEN PHOSPHORYLASE; GLYCOSIDASE; HAMMERHEAD RIBOZYME; IMIDAZOLE; LYSOZYME; ORNITHINE CARBAMOYLTRANSFERASE; PEPTIDYLTRANSFERASE; PROTEIN TYROSINE KINASE; RNA; SERINE PROTEINASE; TRYPSIN;

CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME REACTIVATION; ENZYME STABILITY; ENZYME STRUCTURE; ENZYMOLOGY; GENE MUTATION; GENETIC DISORDER; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MUTANT; NONHUMAN; ORGANIC CHEMISTRY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

EID: 41749110684     PISSN: 18723136     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231308783334162     Document Type: Review

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