Role of an active site guanine in hairpin ribozyme catalysis probed by exogenous nucleobase rescue

Journal of Molecular Biology

Volumn 340, Issue 2, 2004, Pages 233-251

  Kuzmin, Yaroslav I ^a   Da Costa, Carla P ^a   Fedor, Martha J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

catalytic mechanism; electrostatic stabilization; general acid base catalysis; hairpin ribozyme; HDV, hepatitis delta virus; NB, nucleobase; RNA catalysis; VS, Varkud satellite

Indexed keywords

ACID; CYTOSINE; GUANINE; NUCLEIC ACID BASE; RIBOZYME;

ARTICLE; CATALYSIS; CATALYST; CONCENTRATION RESPONSE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; PH; PRIORITY JOURNAL; PROTON TRANSPORT; REACTION ANALYSIS; RNA ANALYSIS; RNA CLEAVAGE;

HEPATITIS DELTA VIRUS;

EID: 2942577491     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.04.067     Document Type: Article

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