Chemical rescue of histidine selectivity filter mutants of the M2 ion channel of influenza A virus

Journal of Biological Chemistry

Volumn 280, Issue 22, 2005, Pages 21463-21472

  Venkataraman, Padmavati ^a   Lamb, Robert A ^a   Pinto, Lawrence H ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE CONTROL; IONS; MOLECULAR DYNAMICS; MUTAGENESIS; PROTEINS; SUBSTITUTION REACTIONS; VIRUSES;

ACIDIFICATION; CHANNEL PORE; ION CHANNELS; MUTANTS;

AMINO ACIDS;

1 METHYLIMIDAZOLE; 2 HYDROXY 3 MORPHOLINOPROPANESULFONIC ACID; 4 MORPHOLINEETHANESULFONIC ACID; BUFFER; HISTIDINE; IMIDAZOLE; ION CHANNEL; MORPHOLINE DERIVATIVE; MUTANT PROTEIN; PROTEIN M2; SULFONIC ACID DERIVATIVE; TRYPTOPHAN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; INFLUENZA VIRUS A; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON TRANSPORT; WILD TYPE;

ALKANESULFONIC ACIDS; AMANTADINE; ANIMALS; BUFFERS; CELL MEMBRANE; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOSOMES; GENOTYPE; HISTIDINE; HYDROGEN-ION CONCENTRATION; IMIDAZOLES; IONS; KINETICS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MORPHOLINES; MUTATION; OOCYTES; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTONS; RNA, MESSENGER; SULFONIC ACIDS; TIME FACTORS; TRYPTOPHAN; VIRAL MATRIX PROTEINS; XENOPUS LAEVIS;

INFLUENZA A VIRUS; INFLUENZA VIRUS;

EID: 20444385829     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412406200     Document Type: Article

References (42)

1. Hay, A. J. (1992) Semin. Virol. 3, 21-30
2. Lamb, R. A., Holsinger, L. J., and Pinto, L. H. (1994) in Receptor-mediated Virus Entry into Cells (Wimmer, E., ed) pp. 303-321, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
3. Lamb, R. A., and Pinto, L. H. (2005) in Contemporary Topics in Influenza Virology (Kawaoka, Y., ed) Horizon Scientific Press, Wymondham, Norfolk, UK, in press
4. Pinto, L. H., Holsinger, L. J., and Lamb, R. A. (1992) Cell 69, 517-528
5. Wang, C., Takeuchi, K., Pinto, L. H., and Lamb, R. A. (1993) J. Virol. 67, 5585-5594
6. Chizhmakov, I. V., Geraghty, F. M., Ogden, D. C., Hayhurst, A., Antoniou, M., and Hay, A. J. (1996) J. Physiol. (Lond.) 494, 329-336
7. Lamb, R. A., Zebedee, S. L., and Richardson, C. D. (1985) Cell 40, 627-633
8. Sugrue, R. J., and Hay, A. J. (1991) Virology 180, 617-624
9. Holsinger, L. J., and Lamb, R. A. (1991) Virology 183, 32-43
10. Panayotov, P. P., and Schlesinger, R. W. (1992) Virology 186, 352-355
11. Sakaguchi, T., Tu, Q., Pinto, L. H., and Lamb, R. A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5000-5005
12. Wang, C., Lamb, R. A., and Pinto, L. H. (1994) Virology 205, 133-140
13. Tu, Q., Pinto, L. H., Luo, G., Shaughnessy, M. A., Mullaney, D., Kurtz, S., Krystal, M., and Lamb, R. A. (1996) J. Virol. 70, 4246-4252
14. Kurtz, S., Luo, G., Hahnenberger, K. M., Brooks, C., Gecha, O., Ingalls, K., Numata, K., and Krystal, M. (1995) Antimicrob. Agents Chemother. 39, 2204-2209
15. Duff, K. C., and Ashley, R. H. (1992) Virology 190, 485-489
16. Tosteson, M. T., Pinto, L. H., Holsinger, L. J., and Lamb, R. A. (1994) J. Membr. Biol. 142, 117-126
17. Lin, T. I., and Schroeder, C. (2001) J. Virol. 75, 3647-3656
18. Mould, J. A., Drury, J. E., Frings, S. M., Kaupp, U. B., Pekosz, A., Lamb, R. A., and Pinto, L. H. (2000) J. Biol. Chem. 275, 31038-31050
19. Shimbo, K., Brassard, D. L., Lamb, R. A., and Pinto, L. H. (1996) Biophys. J. 70, 1336-1346
20. Okada, A., Miura, T., and Takeuchi, H. (2001) Biochemistry 40, 6053-6060
21. Tang, Y., Zaitseva, F., Lamb, R. A., and Pinto, L. H. (2002) J. Biol. Chem. 277, 39880-39886
22. Wang, C., Lamb, R. A., and Pinto, L. H. (1995) Biophys. J. 69, 1363-1371
23. Tu, C. K., Silverman, D. N., Forsman, C., Jonsson, B. H., and Lindskog, S. (1989) Biochemistry 28, 7913-7918
24. Tu, C., Rowlett, R. S., Tripp, B. C., Ferry, J. G., and Silverman, D. N. (2002) Biochemistry 41, 15429-15435
25. Duda, D., Govindasamy, L., Agbandje-McKenna, M., Tu, C., Silverman, D. N., and McKenna, R. (2003) Acta Crystallogr. Sect. D. Biol. Crystallogr. 59, 93-104
26. Matsunami, H., Okajima, T., Hirota, S., Yamaguchi, H., Hori, H., Kuroda, S., and Tanizawa, K. (2004) Biochemistry 43, 2178-2187
27. Hopkins, C. E., O'Connor, P. B., Allen, K. N., Costello, C. E., and Tolan, D. R. (2002) Protein Sci. 11, 1591-1599
28. Lehoux, I. E., and Mitra, B. (1999) Biochemistry 38, 9948-9955
29. Huang, S., and Tu, S. C. (1997) Biochemistry 36, 14609-14615
30. Adelroth, P., Paddock, M. L., Tehrani, A., Beatty, J. T., Feher, G., and Okamura, M. Y. (2001) Biochemistry 40, 14538-14546
31. Admiraal, S. J., Schneider, B., Meyer, P., Janin, J., Veron, M., Deville-Bonne, D., and Herschlag, D. (1999) Biochemistry 38, 4701-4711
32. Swansea, R., Marshall, J., Smith, J. S., Williams, J. B., Boyle, M. B., Folander, K., Luneau, C. J., Antanavage, J., Oliva, C., Buhrow, S. A., Bennett, C., Stein, R. B., and Kaczmarek, L. M. (1990) Neuron 4, 929-939
33. Zebedee, S. L., and Lamb, R. A. (1988) J. Virol. 62, 2762-2772
34. Mould, J. A., Li, H.-C., Dudlak, C. S., Lear, J. D., Pekosz, A., Lamb, R. A., and Pinto, L. H. (2000) J. Biol. Chem. 275, 8592-8599
35. Gandhi, C. S., Shuck, K., Lear, J. D., Dieckmann, G. R., DeGrado, W. F., Lamb, R. A., and Pinto, L. H. (1999) J. Biol. Chem. 274, 5474-5482
36. Duda, D., Tu, C., Qian, M., Laipis, P., Agbandje-McKenna, M., Silverman, D. N., and McKenna, R. (2001) Biochemistry 40, 1741-1748
37. An, H., Tu, C., Duda, D., Montanez-Clemente, I., Math, K., Laipis, P. J., McKenna, R., and Silverman, D. N. (2002) Biochemistry 41, 3235-3242
38. Paddock, M. L., Adelroth, P., Feher, G., Okamura, M. Y., and Beatty, J. T. (2002) Biochemistry 41, 14716-14725
39. Shuck, K., Lamb, R. A., and Pinto, L. H. (2000) J. Virol. 74, 7755-7761
40. Pinto, L. H., Dieckmarm, G. R., Gandhi, C. S., Shaughnessy, M. A., Papworth, C. G., Braman, J., Lear, J. D., Lamb, R. A., and DeGrado, W. F. (1997) Proc. Natl. Acad. Sci. U. S.A. 94, 11301-11306
41. Smondyrev, A. M., and Voth, G. A. (2002) Biophys. J. 83, 1987-1996
42. Vijayvergiya, V., Wilson, R., Chorak, A., Gao, P. F., Cross, T. A., and Busath, D. D. (2004) Biophys. J. 87, 1697-1704