Rescue of an abasic hairpin ribozyme by cationic nucleobases: Evidence for a novel mechanism of RNA catalysis

Chemistry and Biology

Volumn 9, Issue 4, 2002, Pages 465-473

  Lebruska, Lori L ^a   Kuzmine, Iaroslav I ^a   Fedor, Martha J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RIBOZYME;

ARTICLE; CATALYSIS; CHEMICAL MODEL; CHEMISTRY; ELECTRICITY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PH; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

BASE SEQUENCE; CATALYSIS; CATIONS; ELECTROSTATICS; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PURINES; PYRIMIDINES; RNA, CATALYTIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036237379     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00130-8     Document Type: Article

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31. Inter-domain cross-linking and molecular modelling of the hairpin ribozyme
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34. Kinetics and thermodynamics of intermolecular catalysis by hairpin ribozymes
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51. Electronic structure and reactivity
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53. Divalent metal ions in RNA folding and catalysis
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57. In vitro selection of self-cleaving RNAs with a low pH optimum