Imidazole-induced cell death, associated with intracellular acidification, caspase-3 activation, DFF-45 cleavage, but not oligonucleosomal DNA fragmentation

Apoptosis

Volumn 7, Issue 6, 2002, Pages 519-525

  Iguchi, K ^a   Usui, S ^a   Ishida, R ^b   Hirano, K ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b Ichinomiya Public Health Center   (Japan)

Author keywords

Acidification; Intracellular pH; Neutralization

Indexed keywords

CASPASE 3; CASPASE INHIBITOR; DFF 45; DNA FRAGMENT; IMIDAZOLE DERIVATIVE; OLIGONUCLEOTIDE; PROTEIN; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASPASE; DNA FRAGMENTATION FACTOR, HUMAN; IMIDAZOLE;

ACIDIFICATION; APOPTOSIS; ARTICLE; CELL DEATH; CELL PH; CELL STRAIN HL 60; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; WESTERN BLOTTING; DRUG EFFECT; INTRACELLULAR FLUID; METABOLISM; PH; PHYSIOLOGY;

APOPTOSIS; CASPASE 3; CASPASES; DNA FRAGMENTATION; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; IMIDAZOLES; INTRACELLULAR FLUID; PROTEINS;

EID: 0036889449     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020691026578     Document Type: Article

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