Mechanism of inactivation of ornithine transcarbamoylase by N(δ)-(N'- sulfodiaminophosphinyl)-L-ornithine, a true transition state analogue?: Crystal structure and implications for catalytic mechanism

Journal of Biological Chemistry

Volumn 275, Issue 26, 2000, Pages 20012-20019

  Langley, David B ^a   Templeton, Matthew D ^b   Fields, Barry A ^a   Mitchell, Robin E ^b   Collyer, Charles A ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

DIAMINE DERIVATIVE; ORNITHINE CARBAMOYLTRANSFERASE; ORNITHINE DERIVATIVE; PHOSPHINE DERIVATIVE; SULFUR DERIVATIVE;

ARTICLE; BINDING KINETICS; CRYSTAL STRUCTURE; ENANTIOMER; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME STRUCTURE; HYDROGEN BOND; PRIORITY JOURNAL;

BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; ESCHERICHIA COLI; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NITROGEN; ORNITHINE; ORNITHINE CARBAMOYLTRANSFERASE; PROTEIN CONFORMATION; TIME FACTORS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PSEUDOMONAS; PSEUDOMONAS SYRINGAE; PSEUDOMONAS SYRINGAE PV. PHASEOLICOLA;

EID: 0034733518     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M000585200     Document Type: Article

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