-
1
-
-
28644451449
-
Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
-
Ito M., Liu Y., Yang Z., et al. Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med 11 12 (2005) 1351-1354
-
(2005)
Nat Med
, vol.11
, Issue.12
, pp. 1351-1354
-
-
Ito, M.1
Liu, Y.2
Yang, Z.3
-
2
-
-
0034098046
-
The 500 Dalton rule for the skin penetration of chemical compounds and drugs
-
Bos J.D., and Meinardi M.M. The 500 Dalton rule for the skin penetration of chemical compounds and drugs. Exp Dermatol 9 3 (2000) 165-169
-
(2000)
Exp Dermatol
, vol.9
, Issue.3
, pp. 165-169
-
-
Bos, J.D.1
Meinardi, M.M.2
-
3
-
-
0032577975
-
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
-
Furuse M., Fujita K., Hiiragi T., Fujimoto K., and Tsukita S. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141 7 (1998) 1539-1550
-
(1998)
J Cell Biol
, vol.141
, Issue.7
, pp. 1539-1550
-
-
Furuse, M.1
Fujita, K.2
Hiiragi, T.3
Fujimoto, K.4
Tsukita, S.5
-
4
-
-
0037128938
-
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice
-
Furuse M., Hata M., Furuse K., et al. Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol 156 6 (2002) 1099-1111
-
(2002)
J Cell Biol
, vol.156
, Issue.6
, pp. 1099-1111
-
-
Furuse, M.1
Hata, M.2
Furuse, K.3
-
5
-
-
0035897421
-
Desmoglein isoform distribution affects stratum corneum structure and function
-
Elias P.M., Matsuyoshi N., Wu H., et al. Desmoglein isoform distribution affects stratum corneum structure and function. J Cell Biol 153 2 (2001) 243-249
-
(2001)
J Cell Biol
, vol.153
, Issue.2
, pp. 243-249
-
-
Elias, P.M.1
Matsuyoshi, N.2
Wu, H.3
-
6
-
-
0027465539
-
Towards gene therapy for haemophilia B using primary human keratinocytes
-
Gerrard A.J., Hudson D.L., Brownlee G.G., and Watt F.M. Towards gene therapy for haemophilia B using primary human keratinocytes. Nat Genet 3 2 (1993) 180-183
-
(1993)
Nat Genet
, vol.3
, Issue.2
, pp. 180-183
-
-
Gerrard, A.J.1
Hudson, D.L.2
Brownlee, G.G.3
Watt, F.M.4
-
7
-
-
0242418250
-
Immune-mediated loss of transgene expression in skin: implications for cutaneous gene therapy
-
Ghazizadeh S., Kalish R.S., and Taichman L.B. Immune-mediated loss of transgene expression in skin: implications for cutaneous gene therapy. Mol Ther 7 3 (2003) 296-303
-
(2003)
Mol Ther
, vol.7
, Issue.3
, pp. 296-303
-
-
Ghazizadeh, S.1
Kalish, R.S.2
Taichman, L.B.3
-
8
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S., von Kalle C., Schmidt M., et al. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N Engl J Med 348 3 (2003) 255-256
-
(2003)
N Engl J Med
, vol.348
, Issue.3
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
von Kalle, C.2
Schmidt, M.3
-
9
-
-
33845524625
-
Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells
-
Mavilio F., Pellegrini G., Ferrari S., et al. Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat Med 12 12 (2006) 1397-1402
-
(2006)
Nat Med
, vol.12
, Issue.12
, pp. 1397-1402
-
-
Mavilio, F.1
Pellegrini, G.2
Ferrari, S.3
-
10
-
-
0041808932
-
Gene therapy progress and prospects: adenoviral vectors
-
St. George J.A. Gene therapy progress and prospects: adenoviral vectors. Gene Ther 10 14 (2003) 1135-1141
-
(2003)
Gene Ther
, vol.10
, Issue.14
, pp. 1135-1141
-
-
St. George, J.A.1
-
11
-
-
0142089747
-
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
-
Raper S.E., Chirmule N., Lee F.S., et al. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 80 1-2 (2003) 148-158
-
(2003)
Mol Genet Metab
, vol.80
, Issue.1-2
, pp. 148-158
-
-
Raper, S.E.1
Chirmule, N.2
Lee, F.S.3
-
12
-
-
0033557194
-
CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts
-
Hidaka C., Milano E., Leopold P.L., et al. CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts. J Clin Invest 103 4 (1999) 579-587
-
(1999)
J Clin Invest
, vol.103
, Issue.4
, pp. 579-587
-
-
Hidaka, C.1
Milano, E.2
Leopold, P.L.3
-
13
-
-
0033995143
-
Efficient in vitro transfection of human keratinocytes with an adenovirus-enhanced receptor-mediated system
-
Huber M., Limat A., Wagner E., and Hohl D. Efficient in vitro transfection of human keratinocytes with an adenovirus-enhanced receptor-mediated system. J Invest Dermatol 114 4 (2000) 661-666
-
(2000)
J Invest Dermatol
, vol.114
, Issue.4
, pp. 661-666
-
-
Huber, M.1
Limat, A.2
Wagner, E.3
Hohl, D.4
-
14
-
-
0031018741
-
Polycations increase the efficiency of adenovirus-mediated gene transfer to epithelial and endothelial cells in vitro
-
Arcasoy S.M., Latoche J.D., Gondor M., Pitt B.R., and Pilewski J.M. Polycations increase the efficiency of adenovirus-mediated gene transfer to epithelial and endothelial cells in vitro. Gene Ther 4 1 (1997) 32-38
-
(1997)
Gene Ther
, vol.4
, Issue.1
, pp. 32-38
-
-
Arcasoy, S.M.1
Latoche, J.D.2
Gondor, M.3
Pitt, B.R.4
Pilewski, J.M.5
-
15
-
-
33749117374
-
Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds
-
Stoff A., Rivera A.A., Banerjee N.S., et al. Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds. Wound Repair Regen 14 5 (2006) 608-617
-
(2006)
Wound Repair Regen
, vol.14
, Issue.5
, pp. 608-617
-
-
Stoff, A.1
Rivera, A.A.2
Banerjee, N.S.3
-
16
-
-
4644273498
-
Progress in the use of adeno-associated viral vectors for gene therapy
-
Buning H., Braun-Falco M., and Hallek M. Progress in the use of adeno-associated viral vectors for gene therapy. Cells Tissues Organs 177 3 (2004) 139-150
-
(2004)
Cells Tissues Organs
, vol.177
, Issue.3
, pp. 139-150
-
-
Buning, H.1
Braun-Falco, M.2
Hallek, M.3
-
17
-
-
0034608803
-
Ubiquitous human adeno-associated virus type 2 autonomously replicates in differentiating keratinocytes of a normal skin model
-
Meyers C., Mane M., Kokorina N., Alam S., and Hermonat P.L. Ubiquitous human adeno-associated virus type 2 autonomously replicates in differentiating keratinocytes of a normal skin model. Virology 272 2 (2000) 338-346
-
(2000)
Virology
, vol.272
, Issue.2
, pp. 338-346
-
-
Meyers, C.1
Mane, M.2
Kokorina, N.3
Alam, S.4
Hermonat, P.L.5
-
18
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini L., Blomer U., Gallay P., et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272 5259 (1996) 263-267
-
(1996)
Science
, vol.272
, Issue.5259
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
-
19
-
-
0036797451
-
Stable nonviral genetic correction of inherited human skin disease
-
Ortiz-Urda S., Thyagarajan B., Keene D.R., et al. Stable nonviral genetic correction of inherited human skin disease. Nat Med 8 10 (2002) 1166-1170
-
(2002)
Nat Med
, vol.8
, Issue.10
, pp. 1166-1170
-
-
Ortiz-Urda, S.1
Thyagarajan, B.2
Keene, D.R.3
-
20
-
-
0037587235
-
Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer
-
Ortiz-Urda S., Lin Q., Yant S.R., Keene D., Kay M.A., and Khavari P.A. Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer. Gene Ther 10 13 (2003) 1099-1104
-
(2003)
Gene Ther
, vol.10
, Issue.13
, pp. 1099-1104
-
-
Ortiz-Urda, S.1
Lin, Q.2
Yant, S.R.3
Keene, D.4
Kay, M.A.5
Khavari, P.A.6
-
21
-
-
0029032807
-
The feasibility of targeted selective gene therapy of the hair follicle
-
Li L., and Hoffman R.M. The feasibility of targeted selective gene therapy of the hair follicle. Nat Med 1 7 (1995) 705-706
-
(1995)
Nat Med
, vol.1
, Issue.7
, pp. 705-706
-
-
Li, L.1
Hoffman, R.M.2
-
22
-
-
0024597585
-
Increased expression of DNA cointroduced with nuclear protein in adult rat liver
-
Kaneda Y., Iwai K., and Uchida T. Increased expression of DNA cointroduced with nuclear protein in adult rat liver. Science 243 4889 (1989) 375-378
-
(1989)
Science
, vol.243
, Issue.4889
, pp. 375-378
-
-
Kaneda, Y.1
Iwai, K.2
Uchida, T.3
-
23
-
-
0029909473
-
In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid
-
Hayashi S.I., Morishita R., Aoki M., et al. In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid. Gene Ther 3 10 (1996) 878-885
-
(1996)
Gene Ther
, vol.3
, Issue.10
, pp. 878-885
-
-
Hayashi, S.I.1
Morishita, R.2
Aoki, M.3
-
24
-
-
1842336320
-
Vaccination onto bare skin
-
Tang D.C., Shi Z., and Curiel D.T. Vaccination onto bare skin. Nature 388 6644 (1997) 729-730
-
(1997)
Nature
, vol.388
, Issue.6644
, pp. 729-730
-
-
Tang, D.C.1
Shi, Z.2
Curiel, D.T.3
-
25
-
-
0032879349
-
Immunization via hair follicles by topical application of naked DNA to normal skin
-
Fan H., Lin Q., Morrissey G.R., and Khavari P.A. Immunization via hair follicles by topical application of naked DNA to normal skin. Nat Biotechnol 17 9 (1999) 870-872
-
(1999)
Nat Biotechnol
, vol.17
, Issue.9
, pp. 870-872
-
-
Fan, H.1
Lin, Q.2
Morrissey, G.R.3
Khavari, P.A.4
-
26
-
-
0030855813
-
In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction
-
Morishita R., Sugimoto T., Aoki M., et al. In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction. Nat Med 3 8 (1997) 894-899
-
(1997)
Nat Med
, vol.3
, Issue.8
, pp. 894-899
-
-
Morishita, R.1
Sugimoto, T.2
Aoki, M.3
-
27
-
-
0036740350
-
Prevention and regression of atopic dermatitis by ointment containing NFκB decoy oligodeoxynucleotides in NC/Nga atopic mouse model
-
Nakamura H., Aoki M., Tamai K., et al. Prevention and regression of atopic dermatitis by ointment containing NFκB decoy oligodeoxynucleotides in NC/Nga atopic mouse model. Gene Ther 9 18 (2002) 1221-1229
-
(2002)
Gene Ther
, vol.9
, Issue.18
, pp. 1221-1229
-
-
Nakamura, H.1
Aoki, M.2
Tamai, K.3
-
28
-
-
0029053818
-
Cytokine gene expression in epidermis with biological effects following injection of naked DNA
-
Hengge U.R., Chan E.F., Foster R.A., Walker P.S., and Vogel J.C. Cytokine gene expression in epidermis with biological effects following injection of naked DNA. Nat Genet 10 2 (1995) 161-166
-
(1995)
Nat Genet
, vol.10
, Issue.2
, pp. 161-166
-
-
Hengge, U.R.1
Chan, E.F.2
Foster, R.A.3
Walker, P.S.4
Vogel, J.C.5
-
29
-
-
0032521154
-
Keratinocyte gene therapy for systemic diseases. Circulating interleukin 10 released from gene-transferred keratinocytes inhibits contact hypersensitivity at distant areas of the skin
-
Meng X., Sawamura D., Tamai K., Hanada K., Ishida H., and Hashimoto I. Keratinocyte gene therapy for systemic diseases. Circulating interleukin 10 released from gene-transferred keratinocytes inhibits contact hypersensitivity at distant areas of the skin. J Clin Invest 101 6 (1998) 1462-1467
-
(1998)
J Clin Invest
, vol.101
, Issue.6
, pp. 1462-1467
-
-
Meng, X.1
Sawamura, D.2
Tamai, K.3
Hanada, K.4
Ishida, H.5
Hashimoto, I.6
-
30
-
-
0036283620
-
The majority of keratinocytes incorporate intradermally injected plasmid DNA regardless of size but only a small proportion of cells can express the gene product
-
Sawamura D., Yasukawa K., Kodama K., et al. The majority of keratinocytes incorporate intradermally injected plasmid DNA regardless of size but only a small proportion of cells can express the gene product. J Invest Dermatol 118 6 (2002) 967-971
-
(2002)
J Invest Dermatol
, vol.118
, Issue.6
, pp. 967-971
-
-
Sawamura, D.1
Yasukawa, K.2
Kodama, K.3
-
31
-
-
4344570380
-
Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo
-
Woodley D.T., Keene D.R., Atha T., et al. Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo. Mol Ther 10 2 (2004) 318-326
-
(2004)
Mol Ther
, vol.10
, Issue.2
, pp. 318-326
-
-
Woodley, D.T.1
Keene, D.R.2
Atha, T.3
-
32
-
-
11144223715
-
Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice
-
Marchetto M.C., Muotri A.R., Burns D.K., Friedberg E.C., and Menck C.F. Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice. Proc Natl Acad Sci USA 101 51 (2004) 17759-17764
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.51
, pp. 17759-17764
-
-
Marchetto, M.C.1
Muotri, A.R.2
Burns, D.K.3
Friedberg, E.C.4
Menck, C.F.5
-
33
-
-
0026067889
-
In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA
-
Titomirov A.V., Sukharev S., and Kistanova E. In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA. Biochim Biophys Acta 1088 1 (1991) 131-134
-
(1991)
Biochim Biophys Acta
, vol.1088
, Issue.1
, pp. 131-134
-
-
Titomirov, A.V.1
Sukharev, S.2
Kistanova, E.3
-
34
-
-
11144330922
-
Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model
-
Marti G., Ferguson M., Wang J., et al. Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model. Gene Ther 11 24 (2004) 1780-1785
-
(2004)
Gene Ther
, vol.11
, Issue.24
, pp. 1780-1785
-
-
Marti, G.1
Ferguson, M.2
Wang, J.3
-
35
-
-
0034990926
-
Cutaneous transfection and immune responses to intradermal nucleic acid vaccination are significantly enhanced by in vivo electropermeabilization
-
Drabick J.J., Glasspool-Malone J., King A., and Malone R.W. Cutaneous transfection and immune responses to intradermal nucleic acid vaccination are significantly enhanced by in vivo electropermeabilization. Mol Ther 3 2 (2001) 249-255
-
(2001)
Mol Ther
, vol.3
, Issue.2
, pp. 249-255
-
-
Drabick, J.J.1
Glasspool-Malone, J.2
King, A.3
Malone, R.W.4
-
36
-
-
0035045987
-
Topical gene transfer into rat skin using electroporation
-
Dujardin N., Van Der Smissen P., and Preat V. Topical gene transfer into rat skin using electroporation. Pharm Res 18 1 (2001) 61-66
-
(2001)
Pharm Res
, vol.18
, Issue.1
, pp. 61-66
-
-
Dujardin, N.1
Van Der Smissen, P.2
Preat, V.3
-
37
-
-
1242341265
-
Improvement of dermatitis by iontophoretically delivered antisense oligonucleotides for interleukin-10 in NC/Nga mice
-
Sakamoto T., Miyazaki E., Aramaki Y., et al. Improvement of dermatitis by iontophoretically delivered antisense oligonucleotides for interleukin-10 in NC/Nga mice. Gene Ther 11 3 (2004) 317-324
-
(2004)
Gene Ther
, vol.11
, Issue.3
, pp. 317-324
-
-
Sakamoto, T.1
Miyazaki, E.2
Aramaki, Y.3
-
38
-
-
0036113958
-
Fetal gene transfer by intrauterine injection with microbubble-enhanced ultrasound
-
Endoh M., Koibuchi N., Sato M., et al. Fetal gene transfer by intrauterine injection with microbubble-enhanced ultrasound. Mol Ther 5 5 Pt 1 (2002) 501-508
-
(2002)
Mol Ther
, vol.5
, Issue.5 PART 1
, pp. 501-508
-
-
Endoh, M.1
Koibuchi, N.2
Sato, M.3
-
39
-
-
0025771965
-
Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles
-
Williams R.S., Johnston S.A., Riedy M., DeVit M.J., McElligott S.G., and Sanford J.C. Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles. Proc Natl Acad Sci USA 88 7 (1991) 2726-2730
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, Issue.7
, pp. 2726-2730
-
-
Williams, R.S.1
Johnston, S.A.2
Riedy, M.3
DeVit, M.J.4
McElligott, S.G.5
Sanford, J.C.6
-
40
-
-
0028940375
-
In vivo cytokine gene transfer by gene gun reduces tumor growth in mice
-
Sun W.H., Burkholder J.K., Sun J., et al. In vivo cytokine gene transfer by gene gun reduces tumor growth in mice. Proc Natl Acad Sci USA 92 7 (1995) 2889-2893
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.7
, pp. 2889-2893
-
-
Sun, W.H.1
Burkholder, J.K.2
Sun, J.3
-
41
-
-
33748856603
-
Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases
-
Fuller D.H., Loudon P., and Schmaljohn C. Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases. Methods 40 1 (2006) 86-97
-
(2006)
Methods
, vol.40
, Issue.1
, pp. 86-97
-
-
Fuller, D.H.1
Loudon, P.2
Schmaljohn, C.3
-
42
-
-
0027379355
-
Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery
-
Prausnitz M.R., Bose V.G., Langer R., and Weaver J.C. Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery. Proc Natl Acad Sci USA 90 22 (1993) 10504-10508
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.22
, pp. 10504-10508
-
-
Prausnitz, M.R.1
Bose, V.G.2
Langer, R.3
Weaver, J.C.4
-
43
-
-
0034005583
-
Transdermal delivery of macromolecules using skin electroporation
-
Lombry C., Dujardin N., and Preat V. Transdermal delivery of macromolecules using skin electroporation. Pharm Res 17 1 (2000) 32-37
-
(2000)
Pharm Res
, vol.17
, Issue.1
, pp. 32-37
-
-
Lombry, C.1
Dujardin, N.2
Preat, V.3
-
44
-
-
1542298892
-
Iontophoretic drug delivery
-
Kalia Y.N., Naik A., Garrison J., and Guy R.H. Iontophoretic drug delivery. Adv Drug Deliv Rev 56 5 (2004) 619-658
-
(2004)
Adv Drug Deliv Rev
, vol.56
, Issue.5
, pp. 619-658
-
-
Kalia, Y.N.1
Naik, A.2
Garrison, J.3
Guy, R.H.4
-
45
-
-
20444413826
-
Transdermal iontophoresis: combination strategies to improve transdermal iontophoretic drug delivery
-
Wang Y., Thakur R., Fan Q., and Michniak B. Transdermal iontophoresis: combination strategies to improve transdermal iontophoretic drug delivery. Eur J Pharm Biopharm 60 2 (2005) 179-191
-
(2005)
Eur J Pharm Biopharm
, vol.60
, Issue.2
, pp. 179-191
-
-
Wang, Y.1
Thakur, R.2
Fan, Q.3
Michniak, B.4
-
46
-
-
14944376721
-
Healing sound: the use of ultrasound in drug delivery and other therapeutic applications
-
Mitragotri S. Healing sound: the use of ultrasound in drug delivery and other therapeutic applications. Nat Rev Drug Discov 4 3 (2005) 255-260
-
(2005)
Nat Rev Drug Discov
, vol.4
, Issue.3
, pp. 255-260
-
-
Mitragotri, S.1
-
47
-
-
0032956744
-
Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations
-
Marjukka Suhonen T., Bouwstra J.A., and Urtti A. Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations. J Control Release 59 2 (1999) 149-161
-
(1999)
J Control Release
, vol.59
, Issue.2
, pp. 149-161
-
-
Marjukka Suhonen, T.1
Bouwstra, J.A.2
Urtti, A.3
-
48
-
-
0742288421
-
Discovery of transdermal penetration enhancers by high-throughput screening
-
Karande P., Jain A., and Mitragotri S. Discovery of transdermal penetration enhancers by high-throughput screening. Nat Biotechnol 22 2 (2004) 192-197
-
(2004)
Nat Biotechnol
, vol.22
, Issue.2
, pp. 192-197
-
-
Karande, P.1
Jain, A.2
Mitragotri, S.3
-
50
-
-
0036105150
-
Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery
-
Mikszta J.A., Alarcon J.B., Brittingham J.M., Sutter D.E., Pettis R.J., and Harvey N.G. Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery. Nat Med 8 4 (2002) 415-419
-
(2002)
Nat Med
, vol.8
, Issue.4
, pp. 415-419
-
-
Mikszta, J.A.1
Alarcon, J.B.2
Brittingham, J.M.3
Sutter, D.E.4
Pettis, R.J.5
Harvey, N.G.6
-
51
-
-
0344737700
-
CD4+CD25+ regulatory T cells inhibit immune-mediated transgene rejection
-
Gross D.A., Leboeuf M., Gjata B., Danos O., and Davoust J. CD4+CD25+ regulatory T cells inhibit immune-mediated transgene rejection. Blood 102 13 (2003) 4326-4328
-
(2003)
Blood
, vol.102
, Issue.13
, pp. 4326-4328
-
-
Gross, D.A.1
Leboeuf, M.2
Gjata, B.3
Danos, O.4
Davoust, J.5
-
52
-
-
0141856330
-
Engraftment of retroviral EGFP-transduced bone marrow in mice prevents rejection of EGFP-transgenic skin grafts
-
Andersson G., Denaro M., Johnson K., et al. Engraftment of retroviral EGFP-transduced bone marrow in mice prevents rejection of EGFP-transgenic skin grafts. Mol Ther 8 3 (2003) 385-391
-
(2003)
Mol Ther
, vol.8
, Issue.3
, pp. 385-391
-
-
Andersson, G.1
Denaro, M.2
Johnson, K.3
-
53
-
-
0032503628
-
Corrective transduction of human epidermal stem cells in laminin-5-dependent junctional epidermolysis bullosa
-
Dellambra E., Vailly J., Pellegrini G., et al. Corrective transduction of human epidermal stem cells in laminin-5-dependent junctional epidermolysis bullosa. Hum Gene Ther 9 9 (1998) 1359-1370
-
(1998)
Hum Gene Ther
, vol.9
, Issue.9
, pp. 1359-1370
-
-
Dellambra, E.1
Vailly, J.2
Pellegrini, G.3
-
54
-
-
0031787239
-
Corrective gene transfer of keratinocytes from patients with junctional epidermolysis bullosa restores assembly of hemidesmosomes in reconstructed epithelia
-
Vailly J., Gagnoux-Palacios L., Dell'Ambra E., et al. Corrective gene transfer of keratinocytes from patients with junctional epidermolysis bullosa restores assembly of hemidesmosomes in reconstructed epithelia. Gene Ther 5 10 (1998) 1322-1332
-
(1998)
Gene Ther
, vol.5
, Issue.10
, pp. 1322-1332
-
-
Vailly, J.1
Gagnoux-Palacios, L.2
Dell'Ambra, E.3
-
55
-
-
0032897775
-
BP180 gene delivery in junctional epidermolysis bullosa
-
Seitz C.S., Giudice G.J., Balding S.D., Marinkovich M.P., and Khavari P.A. BP180 gene delivery in junctional epidermolysis bullosa. Gene Ther 6 1 (1999) 42-47
-
(1999)
Gene Ther
, vol.6
, Issue.1
, pp. 42-47
-
-
Seitz, C.S.1
Giudice, G.J.2
Balding, S.D.3
Marinkovich, M.P.4
Khavari, P.A.5
-
56
-
-
0035942278
-
In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa
-
Robbins P.B., Lin Q., Goodnough J.B., Tian H., Chen X., and Khavari P.A. In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa. Proc Natl Acad Sci USA 98 9 (2001) 5193-5198
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.9
, pp. 5193-5198
-
-
Robbins, P.B.1
Lin, Q.2
Goodnough, J.B.3
Tian, H.4
Chen, X.5
Khavari, P.A.6
-
57
-
-
0035798605
-
Gene correction of integrin beta4-dependent pyloric atresia-junctional epidermolysis bullosa keratinocytes establishes a role for beta4 tyrosines 1422 and 1440 in hemidesmosome assembly
-
Dellambra E., Prislei S., Salvati A.L., et al. Gene correction of integrin beta4-dependent pyloric atresia-junctional epidermolysis bullosa keratinocytes establishes a role for beta4 tyrosines 1422 and 1440 in hemidesmosome assembly. J Biol Chem 276 44 (2001) 41336-41342
-
(2001)
J Biol Chem
, vol.276
, Issue.44
, pp. 41336-41342
-
-
Dellambra, E.1
Prislei, S.2
Salvati, A.L.3
-
58
-
-
0038618975
-
PhiC31 integrase-mediated nonviral genetic correction of junctional epidermolysis bullosa
-
Ortiz-Urda S., Thyagarajan B., Keene D.R., Lin Q., Calos M.P., and Khavari P.A. PhiC31 integrase-mediated nonviral genetic correction of junctional epidermolysis bullosa. Hum Gene Ther 14 9 (2003) 923-928
-
(2003)
Hum Gene Ther
, vol.14
, Issue.9
, pp. 923-928
-
-
Ortiz-Urda, S.1
Thyagarajan, B.2
Keene, D.R.3
Lin, Q.4
Calos, M.P.5
Khavari, P.A.6
-
59
-
-
28844454528
-
Sustained phenotypic reversion of junctional epidermolysis bullosa dog keratinocytes: establishment of an immunocompetent animal model for cutaneous gene therapy
-
Spirito F., Capt A., Del Rio M., et al. Sustained phenotypic reversion of junctional epidermolysis bullosa dog keratinocytes: establishment of an immunocompetent animal model for cutaneous gene therapy. Biochem Biophys Res Commun 339 3 (2006) 769-778
-
(2006)
Biochem Biophys Res Commun
, vol.339
, Issue.3
, pp. 769-778
-
-
Spirito, F.1
Capt, A.2
Del Rio, M.3
-
60
-
-
33751173879
-
Evaluation of prenatal intra-amniotic LAMB3 gene delivery in a mouse model of Herlitz disease
-
Muhle C., Neuner A., Park J., et al. Evaluation of prenatal intra-amniotic LAMB3 gene delivery in a mouse model of Herlitz disease. Gene Ther 13 23 (2006) 1665-1676
-
(2006)
Gene Ther
, vol.13
, Issue.23
, pp. 1665-1676
-
-
Muhle, C.1
Neuner, A.2
Park, J.3
-
61
-
-
0034637611
-
Development and characterization of a recombinant truncated type VII collagen "minigene". Implication for gene therapy of dystrophic epidermolysis bullosa
-
Chen M., O'Toole E.A., Muellenhoff M., Medina E., Kasahara N., and Woodley D.T. Development and characterization of a recombinant truncated type VII collagen "minigene". Implication for gene therapy of dystrophic epidermolysis bullosa. J Biol Chem 275 32 (2000) 24429-24435
-
(2000)
J Biol Chem
, vol.275
, Issue.32
, pp. 24429-24435
-
-
Chen, M.1
O'Toole, E.A.2
Muellenhoff, M.3
Medina, E.4
Kasahara, N.5
Woodley, D.T.6
-
62
-
-
0036898193
-
Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa
-
Chen M., Kasahara N., Keene D.R., et al. Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa. Nat Genet 32 4 (2002) 670-675
-
(2002)
Nat Genet
, vol.32
, Issue.4
, pp. 670-675
-
-
Chen, M.1
Kasahara, N.2
Keene, D.R.3
-
63
-
-
0037244019
-
Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue
-
Ortiz-Urda S., Lin Q., Green C.L., Keene D.R., Marinkovich M.P., and Khavari P.A. Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue. J Clin Invest 111 2 (2003) 251-255
-
(2003)
J Clin Invest
, vol.111
, Issue.2
, pp. 251-255
-
-
Ortiz-Urda, S.1
Lin, Q.2
Green, C.L.3
Keene, D.R.4
Marinkovich, M.P.5
Khavari, P.A.6
-
64
-
-
0043133368
-
Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors
-
Baldeschi C., Gache Y., Rattenholl A., et al. Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors. Hum Mol Genet 12 15 (2003) 1897-1905
-
(2003)
Hum Mol Genet
, vol.12
, Issue.15
, pp. 1897-1905
-
-
Baldeschi, C.1
Gache, Y.2
Rattenholl, A.3
-
65
-
-
0242658535
-
Normal and gene-corrected dystrophic epidermolysis bullosa fibroblasts alone can produce type VII collagen at the basement membrane zone
-
Woodley D.T., Krueger G.G., Jorgensen C.M., et al. Normal and gene-corrected dystrophic epidermolysis bullosa fibroblasts alone can produce type VII collagen at the basement membrane zone. J Invest Dermatol 121 5 (2003) 1021-1028
-
(2003)
J Invest Dermatol
, vol.121
, Issue.5
, pp. 1021-1028
-
-
Woodley, D.T.1
Krueger, G.G.2
Jorgensen, C.M.3
-
66
-
-
5444220729
-
Construction of skin equivalents for gene therapy of recessive dystrophic epidermolysis bullosa
-
Gache Y., Baldeschi C., Del Rio M., et al. Construction of skin equivalents for gene therapy of recessive dystrophic epidermolysis bullosa. Hum Gene Ther 15 10 (2004) 921-933
-
(2004)
Hum Gene Ther
, vol.15
, Issue.10
, pp. 921-933
-
-
Gache, Y.1
Baldeschi, C.2
Del Rio, M.3
-
67
-
-
33645020760
-
Fibroblasts show more potential as target cells than keratinocytes in COL7A1 gene therapy of dystrophic epidermolysis bullosa
-
Goto M., Sawamura D., Ito K., et al. Fibroblasts show more potential as target cells than keratinocytes in COL7A1 gene therapy of dystrophic epidermolysis bullosa. J Invest Dermatol 126 4 (2006) 766-772
-
(2006)
J Invest Dermatol
, vol.126
, Issue.4
, pp. 766-772
-
-
Goto, M.1
Sawamura, D.2
Ito, K.3
-
68
-
-
33751119265
-
Targeted skipping of a single exon harboring a premature termination codon mutation: implications and potential for gene correction therapy for selective dystrophic epidermolysis bullosa patients
-
Goto M., Sawamura D., Nishie W., et al. Targeted skipping of a single exon harboring a premature termination codon mutation: implications and potential for gene correction therapy for selective dystrophic epidermolysis bullosa patients. J Invest Dermatol 126 12 (2006) 2614-2620
-
(2006)
J Invest Dermatol
, vol.126
, Issue.12
, pp. 2614-2620
-
-
Goto, M.1
Sawamura, D.2
Nishie, W.3
-
69
-
-
0030462657
-
Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes
-
Choate K.A., Kinsella T.M., Williams M.L., Nolan G.P., and Khavari P.A. Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. Hum Gene Ther 7 18 (1996) 2247-2253
-
(1996)
Hum Gene Ther
, vol.7
, Issue.18
, pp. 2247-2253
-
-
Choate, K.A.1
Kinsella, T.M.2
Williams, M.L.3
Nolan, G.P.4
Khavari, P.A.5
-
70
-
-
33745258203
-
Restoration of fatty aldehyde dehydrogenase deficiency in Sjogren-Larsson syndrome
-
Haug S., and Braun-Falco M. Restoration of fatty aldehyde dehydrogenase deficiency in Sjogren-Larsson syndrome. Gene Ther 13 13 (2006) 1021-1026
-
(2006)
Gene Ther
, vol.13
, Issue.13
, pp. 1021-1026
-
-
Haug, S.1
Braun-Falco, M.2
-
71
-
-
0027141997
-
Correction of steroid sulfatase deficiency by gene transfer into basal cells of tissue-cultured epidermis from patients with recessive X-linked ichthyosis
-
Jensen T.G., Jensen U.B., Jensen P.K., et al. Correction of steroid sulfatase deficiency by gene transfer into basal cells of tissue-cultured epidermis from patients with recessive X-linked ichthyosis. Exp Cell Res 209 2 (1993) 392-397
-
(1993)
Exp Cell Res
, vol.209
, Issue.2
, pp. 392-397
-
-
Jensen, T.G.1
Jensen, U.B.2
Jensen, P.K.3
-
72
-
-
0030915869
-
A model of corrective gene transfer in X-linked ichthyosis
-
Freiberg R.A., Choate K.A., Deng H., Alperin E.S., Shapiro L.J., and Khavari P.A. A model of corrective gene transfer in X-linked ichthyosis. Hum Mol Genet 6 6 (1997) 927-933
-
(1997)
Hum Mol Genet
, vol.6
, Issue.6
, pp. 927-933
-
-
Freiberg, R.A.1
Choate, K.A.2
Deng, H.3
Alperin, E.S.4
Shapiro, L.J.5
Khavari, P.A.6
-
73
-
-
0028787760
-
Functional retroviral vector for gene therapy of xeroderma pigmentosum group D patients
-
Carreau M., Quilliet X., Eveno E., et al. Functional retroviral vector for gene therapy of xeroderma pigmentosum group D patients. Hum Gene Ther 6 10 (1995) 1307-1315
-
(1995)
Hum Gene Ther
, vol.6
, Issue.10
, pp. 1307-1315
-
-
Carreau, M.1
Quilliet, X.2
Eveno, E.3
-
74
-
-
0030782132
-
Retrovirus-mediated gene transfer corrects DNA repair defect of xeroderma pigmentosum cells of complementation groups A, B and C
-
Zeng L., Quilliet X., Chevallier-Lagente O., Eveno E., Sarasin A., and Mezzina M. Retrovirus-mediated gene transfer corrects DNA repair defect of xeroderma pigmentosum cells of complementation groups A, B and C. Gene Ther 4 10 (1997) 1077-1084
-
(1997)
Gene Ther
, vol.4
, Issue.10
, pp. 1077-1084
-
-
Zeng, L.1
Quilliet, X.2
Chevallier-Lagente, O.3
Eveno, E.4
Sarasin, A.5
Mezzina, M.6
-
75
-
-
33750337565
-
Functional lentiviral vectors for xeroderma pigmentosum gene therapy
-
Marchetto M.C., Correa R.G., Menck C.F., and Muotri A.R. Functional lentiviral vectors for xeroderma pigmentosum gene therapy. J Biotechnol 126 4 (2006) 424-430
-
(2006)
J Biotechnol
, vol.126
, Issue.4
, pp. 424-430
-
-
Marchetto, M.C.1
Correa, R.G.2
Menck, C.F.3
Muotri, A.R.4
-
76
-
-
0029954549
-
Keratinocytes as a target for gene therapy. Sustained production of erythropoietin in mice by human keratinocytes transduced with an adenoassociated virus vector
-
Descamps V., Blumenfeld N., Beuzard Y., and Perricaudet M. Keratinocytes as a target for gene therapy. Sustained production of erythropoietin in mice by human keratinocytes transduced with an adenoassociated virus vector. Arch Dermatol 132 10 (1996) 1207-1211
-
(1996)
Arch Dermatol
, vol.132
, Issue.10
, pp. 1207-1211
-
-
Descamps, V.1
Blumenfeld, N.2
Beuzard, Y.3
Perricaudet, M.4
-
77
-
-
0030918639
-
Keratinocyte gene therapy for adenosine deaminase deficiency: a model approach for inherited metabolic disorders
-
Fenjves E.S., Schwartz P.M., Blaese R.M., and Taichman L.B. Keratinocyte gene therapy for adenosine deaminase deficiency: a model approach for inherited metabolic disorders. Hum Gene Ther 8 8 (1997) 911-917
-
(1997)
Hum Gene Ther
, vol.8
, Issue.8
, pp. 911-917
-
-
Fenjves, E.S.1
Schwartz, P.M.2
Blaese, R.M.3
Taichman, L.B.4
-
78
-
-
0030832442
-
An ex vivo keratinocyte model for gene therapy of hemophilia B
-
Page S.M., and Brownlee G.G. An ex vivo keratinocyte model for gene therapy of hemophilia B. J Invest Dermatol 109 2 (1997) 139-145
-
(1997)
J Invest Dermatol
, vol.109
, Issue.2
, pp. 139-145
-
-
Page, S.M.1
Brownlee, G.G.2
-
79
-
-
0031581181
-
Retrovirus-mediated gene transfer of ornithine-delta-aminotransferase into keratinocytes from gyrate atrophy patients
-
Jensen T.G., Sullivan D.M., Morgan R.A., et al. Retrovirus-mediated gene transfer of ornithine-delta-aminotransferase into keratinocytes from gyrate atrophy patients. Hum Gene Ther 8 17 (1997) 2125-2132
-
(1997)
Hum Gene Ther
, vol.8
, Issue.17
, pp. 2125-2132
-
-
Jensen, T.G.1
Sullivan, D.M.2
Morgan, R.A.3
-
80
-
-
0030776150
-
Ornithine-delta-aminotransferase expression and ornithine metabolism in cultured epidermal keratinocytes: toward metabolic sink therapy for gyrate atrophy
-
Sullivan D.M., Jensen T.G., Taichman L.B., and Csaky K.G. Ornithine-delta-aminotransferase expression and ornithine metabolism in cultured epidermal keratinocytes: toward metabolic sink therapy for gyrate atrophy. Gene Ther 4 10 (1997) 1036-1044
-
(1997)
Gene Ther
, vol.4
, Issue.10
, pp. 1036-1044
-
-
Sullivan, D.M.1
Jensen, T.G.2
Taichman, L.B.3
Csaky, K.G.4
-
81
-
-
0031885389
-
Differentiation-specific enhancer activity in transduced keratinocytes: a model for epidermal gene therapy
-
Page S.M., and Brownlee G.G. Differentiation-specific enhancer activity in transduced keratinocytes: a model for epidermal gene therapy. Gene Ther 5 3 (1998) 394-402
-
(1998)
Gene Ther
, vol.5
, Issue.3
, pp. 394-402
-
-
Page, S.M.1
Brownlee, G.G.2
-
82
-
-
0034501382
-
Development of a skin-based metabolic sink for phenylalanine by overexpression of phenylalanine hydroxylase and GTP cyclohydrolase in primary human keratinocytes
-
Christensen R., Kolvraa S., Blaese R.M., and Jensen T.G. Development of a skin-based metabolic sink for phenylalanine by overexpression of phenylalanine hydroxylase and GTP cyclohydrolase in primary human keratinocytes. Gene Ther 7 23 (2000) 1971-1978
-
(2000)
Gene Ther
, vol.7
, Issue.23
, pp. 1971-1978
-
-
Christensen, R.1
Kolvraa, S.2
Blaese, R.M.3
Jensen, T.G.4
-
83
-
-
17844410918
-
A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin-targeted keratinocyte grafts
-
Larcher F., Del Rio M., Serrano F., et al. A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin-targeted keratinocyte grafts. FASEB J 15 9 (2001) 1529-1538
-
(2001)
FASEB J
, vol.15
, Issue.9
, pp. 1529-1538
-
-
Larcher, F.1
Del Rio, M.2
Serrano, F.3
-
84
-
-
0035572944
-
Sustainable systemic delivery via a single injection of lentivirus into human skin tissue
-
Beak S.C., Lin Q., Robbins P.B., Fan H., and Khavari P.A. Sustainable systemic delivery via a single injection of lentivirus into human skin tissue. Hum Gene Ther 12 12 (2001) 1551-1558
-
(2001)
Hum Gene Ther
, vol.12
, Issue.12
, pp. 1551-1558
-
-
Beak, S.C.1
Lin, Q.2
Robbins, P.B.3
Fan, H.4
Khavari, P.A.5
-
85
-
-
0036392185
-
Comparison of epidermal keratinocytes and dermal fibroblasts as potential target cells for somatic gene therapy of phenylketonuria
-
Christensen R., Guttler F., and Jensen T.G. Comparison of epidermal keratinocytes and dermal fibroblasts as potential target cells for somatic gene therapy of phenylketonuria. Mol Genet Metab 76 4 (2002) 313-318
-
(2002)
Mol Genet Metab
, vol.76
, Issue.4
, pp. 313-318
-
-
Christensen, R.1
Guttler, F.2
Jensen, T.G.3
-
86
-
-
0036782060
-
Keratinocyte gene therapy: cytokine gene expression in local keratinocytes and in circulation by introducing cytokine genes into skin
-
Meng X., Sawamura D., Ina S., Tamai K., Hanada K., and Hashimoto I. Keratinocyte gene therapy: cytokine gene expression in local keratinocytes and in circulation by introducing cytokine genes into skin. Exp Dermatol 11 5 (2002) 456-461
-
(2002)
Exp Dermatol
, vol.11
, Issue.5
, pp. 456-461
-
-
Meng, X.1
Sawamura, D.2
Ina, S.3
Tamai, K.4
Hanada, K.5
Hashimoto, I.6
-
87
-
-
0642303112
-
Increases in weight of growth hormone-deficient and immunodeficient (lit/scid) dwarf mice after grafting of hGH-secreting, primary human keratinocytes
-
Bellini M.H., Peroni C.N., and Bartolini P. Increases in weight of growth hormone-deficient and immunodeficient (lit/scid) dwarf mice after grafting of hGH-secreting, primary human keratinocytes. FASEB J 17 15 (2003) 2322-2324
-
(2003)
FASEB J
, vol.17
, Issue.15
, pp. 2322-2324
-
-
Bellini, M.H.1
Peroni, C.N.2
Bartolini, P.3
-
88
-
-
19944429826
-
Generation of recombinant skin in vitro by adeno-associated virus type 2 vector transduction
-
Agrawal N., You H., Liu Y., et al. Generation of recombinant skin in vitro by adeno-associated virus type 2 vector transduction. Tissue Eng 10 11-12 (2004) 1707-1715
-
(2004)
Tissue Eng
, vol.10
, Issue.11-12
, pp. 1707-1715
-
-
Agrawal, N.1
You, H.2
Liu, Y.3
-
89
-
-
33845915283
-
High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy
-
Peroni C.N., Cecchi C.R., Damiani R., et al. High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy. Mol Biotechnol 34 2 (2006) 239-245
-
(2006)
Mol Biotechnol
, vol.34
, Issue.2
, pp. 239-245
-
-
Peroni, C.N.1
Cecchi, C.R.2
Damiani, R.3
-
90
-
-
34548064995
-
Efficient production of bioactive insulin from human epidermal keratinocytes and tissue-engineered skin substitutes: implications for treatment of diabetes
-
Lei P., Ogunade A., Kirkwood K.L., Laychock S.G., and Andreadis S.T. Efficient production of bioactive insulin from human epidermal keratinocytes and tissue-engineered skin substitutes: implications for treatment of diabetes. Tissue Eng (2007)
-
(2007)
Tissue Eng
-
-
Lei, P.1
Ogunade, A.2
Kirkwood, K.L.3
Laychock, S.G.4
Andreadis, S.T.5
|