Polycations increase the efficiency of adenovirus-mediated gene transfer to epithelial and endothelial cells in vitro

Gene Therapy

Volumn 4, Issue 1, 1997, Pages 32-38

  Arcasoy, S M ^a   Latoche, J D ^a   Gondor, M ^a   Pitt, B R ^a   Pilewski, J M ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b 440 Scaife Hall ^*  (United States)

Author keywords

Cystic fibrosis; Gene therapy; Glycoconjugates; Polycations; Vascular thrombosis

Indexed keywords

BETA GALACTOSIDASE; DIETHYLAMINOETHYLDEXTRAN; HEPARIN; HEXADIMETHRINE BROMIDE; POLYANION; POLYCATION; POLYLYSINE; PROTAMINE;

ADENOVIRUS; ANIMAL CELL; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; ENDOTHELIUM CELL; EPITHELIUM CELL; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE EXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RESPIRATORY EPITHELIUM; SHEEP;

ADENOVIRIDAE; ANIMALIA; ESCHERICHIA COLI; OVIS ARIES;

EID: 0031018741     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300349     Document Type: Article

References (43)

1. Crystal RG. Transfer of genes to humans: early lessons and obstacles to success. Science 1995; 270: 404-110.
2. Curiel DT, Pilewski JM, Albelda SM. Gene therapy approaches for inherited and acquired lung diseases. Am J Respir Cell Mol Biol 1996; 14: 1-18.
3. Wilson JM. Gene therapy for cystic fibrosis: challenges and future directions. J Clin Invest 1995; 96: 2547-2554.
4. Schneider MD, French BA. The advent of adenovirus. Gene therapy for cardiovascular disease. Circulation 1993; 88: 1937-1942.
5. Mittereder M et al. Evaluation of the efficacy and safety of in vitro, adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA. Hum Gene Ther 1994; 5: 717-729.
6. 1-antitrypsin cDNA to human endothelial cells. Proc Natl Acad Sci USA 1992; 89: 6482-6486.
7. Erzurum SC et al. Protection of human endothelial cells from oxidant injury by adenovirus-mediated transfer of the human catalase cDNA. Nucleic Acids Res 1993; 21: 1607-1612.
8. Rosenfeld MA et al. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell 1992; 68: 143-155.
9. Lemarchand P et al. In vivo adenovirus-mediated gene transfer to lungs via pulmonary artery. J Appl Physiol 1994; 76: 2840-2845.
10. Lemarchand P, Jones M, Yamada I, Crystal RG. In vivo gene transfer and expression in normal, uninjured blood vessels using replication deficient recombinant adenovirus vectors. Circul Res 1993; 72: 1132-1138.
11. Engelhardt J et al. Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: biological efficacy study. Hum Gene Ther 1993; 4: 759-769.
12. Grubb BR et al. Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans. Nature 1994; 371: 802-806.
13. Pilewski JM et al. Adenovirus-mediated gene transfer to submucosal glands in vivo using xenografts. Am J Physiol 1995, 269: L657-L665.
14. Knowles MR et al. A double-blind vehicle-controlled study of adenoviral vector mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. New Engl J Med 1995; 333: 823-831.
15. Zabner J et al. Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis. Clin Invest 1996; 97: 1504-1511.
16. Schachtner SK et al. In vivo adenovirus-mediated gene transfer via the pulmonary artery of rats. Circul Res 1995, 76: 701-709.
17. Cornetta K, Anderson WF. Protamine sulfate as an effective alternative to polybrene in retroviral-mediated gene transfer. J Virol Meth 1989; 23: 187-194.
18. Kahn ML, Lee SW, Dichek DA. Optimization of retroviral-mediated gene transfer into endothelial cells in vitro. Circul Res 1992; 71: 1508-1517.
19. Hesse J, Ebbesen P, Kristensen G. Correlation between polyion effect on cell susceptibility to in vitro infection with murine C-type viruses and polyion effect on some membrane related functions. Intervirology 1978; 9: 173-183.
20. Manning JS, Hackett AJ, Darby NB Jr. Effect of polycations on sensitivity of BALB/3T3 cells to murine leukemia and sarcoma virus infectivity. Appl Microbiol 1971; 22: 1162-1163.
21. Duc-Nguyen H. Enhancing effect of DEAE-dextran on the focus-forming titre of a murine sarcoma virus (Harvey strain). J Virol 1968; 2: 643-644.
22. Toyoshima K, Vogt PK. Enhancement and inhibition of avian sarcoma viruses by polycations and polyanions. Virology 1969; 38: 414-426.
23. Nomura S. Interaction of respiratory syncytial virus with polyanions: enhancement of infectivity with diethylaminoethyl dextran. Proc Soc Exp Biol Med 1968; 128: 163-166.
24. Loh PC, Hashiro GH, Y au JT. Effect of polycations on the early stages of reovirus infection. Microbios 1977; 19: 213-229.
25. Fukudome K, Yoshie O, Konno T. Comparison of human, simian, and bovine rotaviruses for requirement of sialic acid in hemagglutination and cell adsorption. Virology 1989; 172: 196-205.
26. Yolken RH et al. Sialic acid glycoproteins inhibit in vitro and in vivo replication of rotaviruses. J Clin Invest 1987; 79: 148-154.
27. Greber UF, Willetts M, Webster P, Helenius A. Stepwise dismantling of adenovirus 2 during entry into cells. Cell 1993; 75: 477-186.
28. Arcasoy SM et al. MUC1 and other sialoglycoconjugates inhibit adenovirus-mediated gene transfer to epithelial cells. Am J Respir Cell Mol Biol (submitted).
29. Pedroso de Lima MC et al. Target cell membrane sialic acid modulates both binding and fusion activity of influenza virus. Biochim Biophys Acta 1995; 1236: 323-330.
30. Schultze B, Herrler G. Bovine coronavirus uses N-acetyl-9-O-acetylneuraminic acid as a receptor determinant to initiate the infection of cultured cells. J Gen Virol 1992; 73: 901-906.
31. Wickham TJ, Mathias P, Cheresh DA, Nemerov GR. Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment. Cell 1993; 73: 309-319.
32. Chroboczek J, Jacrot B. The sequence of adenovirus fiber: similarities and differences between serotypes 2 and 5. Virology 1987; 161: 549-554.
33. Ishibashi M, Maizel JV Jr. The polypeptides of adenovirus. VI. Early and late glycoproteins. Virology 1974; 57: 409-424.
34. Hennache B, Boulanger P. Biochemical study of KB cell receptor for adenovirus. Biochem J 1977; 166: 237-247.
35. Rose MC. Mucins: structure, function, and role in pulmonary-diseases. Am J Physiol 1992; 263: L413-L429.
36. Shimizu Y, Shaw S. Mucins in the mainstream. Nature 1993; 366: 630-631.
37. Peterson MW, Gruenhaupt D. Protamine increases the permeability of cultured epithelial monolayers. J Appl Physiol 1990; 68: 220-227.
38. Uchida DC et al. Polycations decrease the transepithelial resistance of cultured tracheal epithelial cells. Chest 1992; 101: 335.
39. Hammes M, Singh A. Effect of polycations on permeability of glomerular epithelial cell monolayers to albumin. J Lab Clin Med 1994; 123: 437-446.
40. Rich DP et al. Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis. Hum Gene Ther 1993; 4: 461-476.
41. Armentano DC et al. Characterization of an adenovirus gene transfer vector containing an E4 deletion. Hum Gene Ther 1995; 6: 1343-1353.
42. Pilewski JM, Sott DJ, Wilson JM, Albelda SM. ICAM-1 expression on bronchial epithelium after recombinant adenovirus infection. Am J Respir Cell Mol Biol 1995; 12: 142-148.
43. Hoyt DG et al. Collagen is a survival factor against LPS-induced apoptosis in sheep pulmonary artery endothelial cells. Am J Physiol 1995; 269 (Lung Cell Mol Physiol 13): L171-L177.