Transdermal delivery of macromolecules using skin electroporation

Pharmaceutical Research

Volumn 17, Issue 1, 2000, Pages 32-37

  Lombry, Catherine ^a   Dujardin, Nathalie ^a   Préat, Véronique ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Electroporation; FITC dextrans; Macromolecules; Topical drug delivery; Transdermal drug delivery

Indexed keywords

DRUG;

ANIMAL CELL; ARTICLE; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; ELECTROPORATION; KERATINOCYTE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN ABSORPTION;

ADMINISTRATION, CUTANEOUS; ANIMALS; BIOLOGICAL TRANSPORT; DEXTRANS; DRUG DELIVERY SYSTEMS; ELECTROPORATION; FLUORESCEIN-5-ISOTHIOCYANATE; MALE; MOLECULAR WEIGHT; RATS; SKIN;

EID: 0034005583     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007510323344     Document Type: Article

References (27)

1. 1. J. Hadgraft and R. H. Guy. Transdermal drug delivery. Marcel Dekker (1989).
2. 2. R. H. Guy. Current status and future prospects for transdermal drug delivery. Pharm. Res. 13:1765-1769 (1996).
3. 3. M. R. Prausnitz. Reversible skin permeabilisation for transdermal delivery of macromolecules. Crit. Rev. Ther. Drug Car. Syst. 14:455-483 (1997).
4. 4. M. R. Prausnitz, V. G. Bose, R. Langer, and J. C. Weaver. Electroporation of mammalian skin : a mechanism to enhance transdermal drug delivery. Proc. Nat. Acad. Sci., USA 90:10504-10508 (1993).
5. 5. R. Vanbever, N. Lecouturier, and V. Préat. Transdermal delivery of metoprolol by electroporation. Pharm. Res. 11:1657-1662 (1994).
6. 6. J. C. Weaver and Y. A. Chizmadzhev. Theory of electroporation: a review. Bioelectrochem. Bioenerget. 41:135-160 (1996).
7. 7. R. Vanbever, E. Le Boulangé, and V. Préat. Transdermal delivery of fentanyl by electroporation I. Influence of electrical factors. Pharm. Res. 13:559-565 (1996).
8. 8. J. E. Riviere, N. A. Monteiro-Riviere, R. A. Rogers, D. Bommannan, J. A. Tamada, and R. O. Potts. Pulsatile transdermal delivery of LHRH using electroporation: drug delivery and skin toxicology. J. Contr. Rel. 36:229-233 (1995).
9. 9. M. R. Prausnitz, E. R. Edelman, J. A. Gimm, R. Langer, and J. C. Weaver. Transdermal Delivery of Heparin by skin electroporation. Bio-Technology 13:1205-1209 (1995).
10. 10. T. E. Zewert, U. F. Pliquett, R. Langer, and J. C. Weaver. Transdermal transport of DNA antisense oligonucleotides by electroporation. Biochem. Biophys. Res. Commun. 212:286-292 (1995).
11. 11. V. Regnier, T. Le Doan, and V. Préat. Parameters controlling topical delivery of oligonucleotides by electroporation. J. Drug Target 5:275-289 (1998).
12. 12. V. Regnier and V. Préat. Localisation of a FITC-labeled phosphorothioate oligodeoxynucleotide in the skin after topical delivery by iontophoresis and electroporation. Pharm. Res. 15:1596-1602 (1998).
13. 13. M. J. Jaroszeski, R. Gilbert, C. Nicolau, and R. Heller. In vivo gene delivery by electroporation. Adv. Drug Del. Rev. 35:131-137 (1999).
14. 14. R. Vanbever, U. F. Pliquett, V. Préat, and J. C. Weaver. Comparison of the effects of short, high-voltage and long, medium-voltage pulses on skin electrical and transport properties. J. Contr. Rel. 60:35-47 (1999).
15. 15. C. Cullander and R. H. Guy. Visualization of iontophoretic pathways with confocal microscopy and the vibrating probe electrode. Solid States Ion 53:197-206 (1992).
16. 16. N. G. Turner, L. Ferry, M. Price, C. Cullander, and R. H. Guy. Iontophoresis of poly-L-lysines: The role of molecular weight? Pharm. Res. 14:1322-1331 (1997).
17. 17. R. Vanbever, M. R. Prausnitz, and V. Préat. Macromolecules as novel transdermal transport enhancer for skin electroporation. Pharm.Res. 14:638-644 (1997).
18. 18. J. C. Weaver, R. Vanbever, T. E. Vaughan, and M. R. Prausnitz. Heparin alters transdermal transport associated with electroporation. Biochem. Biophys. Res. Commun. 234:637-640 (1997).
19. 19. L. M. Mir and S. Orlowski. Mechanisms of electrochemotherapy. Adv. Drug Del. Rev. 35:107-118 (1999).
20. 20. M. R. Prausnitz, J. A. Gimm, R. H. Guy, R. Langer, J. C. Weaver, and C. Cullander. Imaging regions of transport across human stratum corneum during high-voltage and low-voltage exposures. J. Pharm. Sci. 85:1363-1370 (1996).
21. 21. U. F. Pliquett, T. E. Zewert, T. Chen, R. Langer, and J. C. Weaver. Imaging of fluorescent molecules and small ion transport through human stratum corneum during high voltage pulsing: localized transport regions are involved. Biophys. Chem. 58:185-204 (1996).
22. 22. U. F. Pliquett, R. Vanbever, V. Préat, and J. C. Weaver. Local transport regions (LTRs) in human stratum comeum due to long and short "high voltage" pulses. Bioelectrochem. Bioenerget. 47:151-161 (1998).
23. 23. V. Préat, R. Vanbever, A. Jadoul, and V. Regnier. Electrically enhanced transdermal drug delivery: iontophoresis vs electroporation. P. Couvreur, D. Duchêne, P. Green, and H. Junginger (eds.), in Transdermal administration: A case study, Iontophoresis. Edition de la Santé, Paris, 1997, pp. 58-67.
24. 24. A. Jadoul, J. Bouwstra, and V. Préat. Effects of iontophoresis and electroporation on the stratum corneum - Review of the biophysical studies. Adv. Drug Del. Rev. 35:89-105 (1999).
25. 25. R. Vanbever, D. Fouchard, A. Jadoul, N. De Morre, V. Préat, and J.-P. Marty. In vivo non-invasive evaluation of hairless rat after high-voltage pulse exposure. Skin Pharmacol. Appl. Skin Physiol. 11:23-34 (1998).
26. 26. M. R. Prausnitz. A practical assessment of transdermal drug delivery by skin electroporation. Adv. Drug Del. Rev. 35:61-76 (1999).
27. 27. S. Wang, M. Kara, and T. R. Krishnan. Topical delivery of cyclosporin A coevaporate using electroporation technique. Drug Dev. Ind. Pharm. 23:657-663 (1997).