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Volumn 59, Issue 2, 1999, Pages 149-161

Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations

Author keywords

Lipid layers; Penetration enhancers; Permeability; Skin; Stratum corneum

Indexed keywords

ALCOHOL; FATTY ACID; FATTY ALCOHOL; LAUROCAPRAM; PENETRATION ENHANCING AGENT; PROPYLENE GLYCOL; WATER;

EID: 0032956744     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00187-4     Document Type: Article
Times cited : (271)

References (106)
  • 3
    • 0016608422 scopus 로고
    • The permeability barrier in mammalian epidermis
    • Elias P.M., Friend D.S. The permeability barrier in mammalian epidermis. J. Cell. Biol. 65:1975;180-191.
    • (1975) J. Cell. Biol. , vol.65 , pp. 180-191
    • Elias, P.M.1    Friend, D.S.2
  • 4
    • 0012020259 scopus 로고
    • Drug metabolism in the skin: advantages and disadvantages
    • in: J. Hadgraft, R.H. Guy (Eds.) Marcel Dekker, New York
    • U. Täuber, Drug metabolism in the skin: advantages and disadvantages, in: J. Hadgraft, R.H. Guy (Eds.), Transdermal Drug Delivery: Developmental Issues and Research Initiatives, Marcel Dekker, New York, 1989, pp. 99-112.
    • (1989) Transdermal Drug Delivery: Developmental Issues and Research Initiatives , pp. 99-112
    • Täuber, U.1
  • 5
    • 0004645716 scopus 로고
    • Chemical and physical methods of enhancing transdermal drug delivery
    • Rolf D. Chemical and physical methods of enhancing transdermal drug delivery. Pharm. Technol. 7:1988;130-140.
    • (1988) Pharm. Technol. , vol.7 , pp. 130-140
    • Rolf, D.1
  • 6
    • 0000804856 scopus 로고
    • Penetration enhancers and their use in transdermal therapeutic systems
    • in: J. Hadgraft, R.H. Guy (Eds.) Marcel Dekker, New York
    • K.A. Walters, Penetration enhancers and their use in transdermal therapeutic systems, in: J. Hadgraft, R.H. Guy (Eds.), Transdermal Drug Delivery: Developmental Issues and Research Initiatives, Marcel Dekker, New York, 1989, pp. 197-246.
    • (1989) Transdermal Drug Delivery: Developmental Issues and Research Initiatives , pp. 197-246
    • Walters, K.A.1
  • 7
    • 0023597397 scopus 로고
    • Mode of action of penetration enhancers in human skin
    • Barry B.W. Mode of action of penetration enhancers in human skin. J. Control. Rel. 6:1987;85-97.
    • (1987) J. Control. Rel. , vol.6 , pp. 85-97
    • Barry, B.W.1
  • 8
    • 0025906898 scopus 로고
    • Lipid-protein-partitioning theory of skin penetration enhancement
    • Barry B.W. Lipid-protein-partitioning theory of skin penetration enhancement. J. Control. Rel. 15:1991;237-248.
    • (1991) J. Control. Rel. , vol.15 , pp. 237-248
    • Barry, B.W.1
  • 9
    • 0025871876 scopus 로고
    • Sustained transdermal delivery of zidovudine via controlled release of penetration enhancer
    • Seki T., Kawaguchi T., Juni K., Sugibayashi K., Morimoto Y. Sustained transdermal delivery of zidovudine via controlled release of penetration enhancer. J. Control. Rel. 17:1991;41-48.
    • (1991) J. Control. Rel. , vol.17 , pp. 41-48
    • Seki, T.1    Kawaguchi, T.2    Juni, K.3    Sugibayashi, K.4    Morimoto, Y.5
  • 10
    • 0025950819 scopus 로고
    • 1-Alkylazacycloalkan-2-one esters as prodrugs of indomethacin for improved delivery through human skin
    • Bonina F.P., Montenegro L., De Capraris P., Bousquet E., Tirendi S. 1-Alkylazacycloalkan-2-one esters as prodrugs of indomethacin for improved delivery through human skin. Int. J. Pharm. 77:1991;21-29.
    • (1991) Int. J. Pharm. , vol.77 , pp. 21-29
    • Bonina, F.P.1    Montenegro, L.2    De Capraris, P.3    Bousquet, E.4    Tirendi, S.5
  • 11
    • 0028641394 scopus 로고
    • Iontophoresis in drug delivery: Basic principles and applications
    • Singh P., Maibach H.I. Iontophoresis in drug delivery: basic principles and applications. Crit. Rev. Ther. Drug Carrier Syst. 11:1994;161-213.
    • (1994) Crit. Rev. Ther. Drug Carrier Syst. , vol.11 , pp. 161-213
    • Singh, P.1    Maibach, H.I.2
  • 12
    • 0027379355 scopus 로고
    • Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery
    • Prausnitz M., Bose V., Langer R., Weaver J. Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery. Proc. Natl. Acad. Sci. USA. 90:1993;10504-10508.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10504-10508
    • Prausnitz, M.1    Bose, V.2    Langer, R.3    Weaver, J.4
  • 14
    • 0002474507 scopus 로고
    • Structure of the skin
    • in: L.A. Goldsmith (Ed.) Oxford University Press, New York
    • G.F. Odland, Structure of the skin, in: L.A. Goldsmith (Ed.), Biochemistry and physiology of the skin, Oxford University Press, New York, 1983, pp. 3-63.
    • (1983) Biochemistry and Physiology of the Skin , pp. 3-63
    • Odland, G.F.1
  • 15
    • 0002391608 scopus 로고
    • Topical drug absorption and topical pharmaceutical systems
    • in: G.S. Banker, C.T. Rhodes (Eds.) Marcel Dekker, New York
    • G.L. Flynn, Topical drug absorption and topical pharmaceutical systems, in: G.S. Banker, C.T. Rhodes (Eds.), Modem Pharmaceutics, Marcel Dekker, New York, 1990, pp. 263-325.
    • (1990) Modem Pharmaceutics , pp. 263-325
    • Flynn, G.L.1
  • 16
    • 0014235613 scopus 로고
    • Studies of the epidermal water barrier. Part II. Investigation of the chemical nature of the water barrier
    • Matoltsy A.G., Downes A.M., Sweeney T.M. Studies of the epidermal water barrier. Part II. Investigation of the chemical nature of the water barrier. J. Invest. Dermatol. 50:1968;19-26.
    • (1968) J. Invest. Dermatol. , vol.50 , pp. 19-26
    • Matoltsy, A.G.1    Downes, A.M.2    Sweeney, T.M.3
  • 17
    • 0024590882 scopus 로고
    • Lipid content and lipid type as determinants of the epidermal permeability barrier
    • Grubauer G., Feingold K.R., Harris R.M., Elias P.M. Lipid content and lipid type as determinants of the epidermal permeability barrier. J. Lipid Res. 30:1989;89-96.
    • (1989) J. Lipid Res. , vol.30 , pp. 89-96
    • Grubauer, G.1    Feingold, K.R.2    Harris, R.M.3    Elias, P.M.4
  • 19
    • 0025851987 scopus 로고
    • The influence of stratum corneum morphology on water permeability
    • Potts R.O., Francoeur M.L. The influence of stratum corneum morphology on water permeability. J. Invest. Dermatol. 96:1991;495-499.
    • (1991) J. Invest. Dermatol. , vol.96 , pp. 495-499
    • Potts, R.O.1    Francoeur, M.L.2
  • 20
    • 0014827372 scopus 로고
    • The role of lipids in the epidermal barrier to water diffusion
    • Sweeney T.M., Downing D.T. The role of lipids in the epidermal barrier to water diffusion. J. Invest. Dermatol. 55:1970;135-140.
    • (1970) J. Invest. Dermatol. , vol.55 , pp. 135-140
    • Sweeney, T.M.1    Downing, D.T.2
  • 21
    • 0025976524 scopus 로고
    • Lipid content and water permeability of skin and oral mucosa
    • Squier C.A., Cox P., Wertz P.W. Lipid content and water permeability of skin and oral mucosa. J. Invest. Dermatol. 96:1991;123-126.
    • (1991) J. Invest. Dermatol. , vol.96 , pp. 123-126
    • Squier, C.A.1    Cox, P.2    Wertz, P.W.3
  • 22
    • 0025819102 scopus 로고
    • Decreased level of ceramides in stratum corneum of atopic dermatitis: An etiologic factor in atopic dry skin?
    • Imokawa G., Abe A., Jin K., Higaki Y., Kawashima M., Hidano A. Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? J. Invest. Dermatol. 96:1991;523-526.
    • (1991) J. Invest. Dermatol. , vol.96 , pp. 523-526
    • Imokawa, G.1    Abe, A.2    Jin, K.3    Higaki, Y.4    Kawashima, M.5    Hidano, A.6
  • 23
    • 0028100996 scopus 로고
    • Quantification of stratum corneum ceramides and lipid envelope ceramides in the hereditary ichthyoses
    • Paige D.G., Morse-Fisher N., Harper J.I. Quantification of stratum corneum ceramides and lipid envelope ceramides in the hereditary ichthyoses. Br. J. Dermatol. 131:1994;23-27.
    • (1994) Br. J. Dermatol. , vol.131 , pp. 23-27
    • Paige, D.G.1    Morse-Fisher, N.2    Harper, J.I.3
  • 24
    • 0027312467 scopus 로고
    • Exogenous lipids influence permeability barrier recovery in acetone-treated murine skin
    • Man M.-Q., Feingold K.R., Elias P.M. Exogenous lipids influence permeability barrier recovery in acetone-treated murine skin. Arch. Dermatol. 129:1993;728-738.
    • (1993) Arch. Dermatol. , vol.129 , pp. 728-738
    • Man, M.-Q.1    Feingold, K.R.2    Elias, P.M.3
  • 25
    • 0028290685 scopus 로고
    • Pseudo-acylceramide with linoleic acid produces selective recovery of diminished cutaneous barrier function in essential fatty acid-deficient rats and has an inhibitory effect on epidermal hyperplasia
    • Imokawa G., Yada Y., Higuchi K., Okuda M., Ohashi Y., Kawamata A. Pseudo-acylceramide with linoleic acid produces selective recovery of diminished cutaneous barrier function in essential fatty acid-deficient rats and has an inhibitory effect on epidermal hyperplasia. J. Clin. Invest. 94:1994;89-96.
    • (1994) J. Clin. Invest. , vol.94 , pp. 89-96
    • Imokawa, G.1    Yada, Y.2    Higuchi, K.3    Okuda, M.4    Ohashi, Y.5    Kawamata, A.6
  • 26
  • 28
    • 0026279967 scopus 로고
    • The biochemistry and function of stratum corneum lipids
    • Schurer N.Y., Elias P.M. The biochemistry and function of stratum corneum lipids. Adv. Lipid Res. 24:1991;27-56.
    • (1991) Adv. Lipid Res. , vol.24 , pp. 27-56
    • Schurer, N.Y.1    Elias, P.M.2
  • 29
    • 0020770892 scopus 로고
    • Ceramides of pig epidermis: Structure determination
    • Wertz P.W., Downing D.T. Ceramides of pig epidermis: structure determination. J. Lipid Res. 24:1983;759-765.
    • (1983) J. Lipid Res. , vol.24 , pp. 759-765
    • Wertz, P.W.1    Downing, D.T.2
  • 31
    • 0017700678 scopus 로고
    • Mammalian epidermal barrier layer lipids: Composition and influence on structure
    • Elias P.M., Goerke J., Friend D.S. Mammalian epidermal barrier layer lipids: composition and influence on structure. J. Invest. Dermatol. 69:1977;535-546.
    • (1977) J. Invest. Dermatol. , vol.69 , pp. 535-546
    • Elias, P.M.1    Goerke, J.2    Friend, D.S.3
  • 32
    • 0344480003 scopus 로고
    • Intercellular volume changes and cell surface area expansion during cornification
    • Elias P.M., Leventhal M.E. Intercellular volume changes and cell surface area expansion during cornification. Clin. Res. 27:1979;525A.
    • (1979) Clin. Res. , vol.27
    • Elias, P.M.1    Leventhal, M.E.2
  • 33
    • 0023271196 scopus 로고
    • The extracellular matrix of stratum corneum: Role of lipids in normal and pathological function
    • Williams M.L., Elias P.M. The extracellular matrix of stratum corneum: Role of lipids in normal and pathological function. CRC Crit. Rev. Ther. Drug Carrier Syst. 3:1987;95-122.
    • (1987) CRC Crit. Rev. Ther. Drug Carrier Syst. , vol.3 , pp. 95-122
    • Williams, M.L.1    Elias, P.M.2
  • 35
    • 0026669010 scopus 로고
    • Structure of human stratum corneum as a function of temperature and hydration: A wide-angle X-ray diffraction study
    • Bouwstra J.A., Gooris G.S., Salomons-de Vries M.A., van der Spek J.A., Bras W. Structure of human stratum corneum as a function of temperature and hydration: A wide-angle X-ray diffraction study. Int. J. Pharm. 84:1992;205-216.
    • (1992) Int. J. Pharm. , vol.84 , pp. 205-216
    • Bouwstra, J.A.1    Gooris, G.S.2    Salomons-De Vries, M.A.3    Van Der Spek, J.A.4    Bras, W.5
  • 36
    • 0025955486 scopus 로고
    • Structural investigations of human stratum corneum by small-angle X-ray scattering
    • Bouwstra J.A., Gooris G.S., van der Spek J.A., Bras W. Structural investigations of human stratum corneum by small-angle X-ray scattering. J. Invest. Dermatol. 97:1991;1005-1012.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 1005-1012
    • Bouwstra, J.A.1    Gooris, G.S.2    Van Der Spek, J.A.3    Bras, W.4
  • 37
    • 0028232051 scopus 로고
    • The lipid and protein structure of mouse stratum corneum: A wide and small angle diffraction study
    • Bouwstra J.A., Gooris G.S., van der Spek J.A., Lavrijsen S., Bras W. The lipid and protein structure of mouse stratum corneum: A wide and small angle diffraction study. Biochim. Biophys. Acta. 1212:1994;183-192.
    • (1994) Biochim. Biophys. Acta , vol.1212 , pp. 183-192
    • Bouwstra, J.A.1    Gooris, G.S.2    Van Der Spek, J.A.3    Lavrijsen, S.4    Bras, W.5
  • 39
    • 0024290394 scopus 로고
    • Structure of lamellar lipid domains and corneocyte envelopes of murine stratum corneum. An X-ray diffraction study
    • White S.H., Mirejovsky D., King G.I. Structure of lamellar lipid domains and corneocyte envelopes of murine stratum corneum. An X-ray diffraction study. Biochemistry. 27:1988;3725-3732.
    • (1988) Biochemistry , vol.27 , pp. 3725-3732
    • White, S.H.1    Mirejovsky, D.2    King, G.I.3
  • 40
    • 0028603370 scopus 로고
    • Wide-angle X-ray diffraction of human stratum corneum: Effects of hydration and terpene enhancer treatment
    • Cornwell P.A., Barry B.W., Stoddart C.P., Bouwstra J.A. Wide-angle X-ray diffraction of human stratum corneum: effects of hydration and terpene enhancer treatment. J. Pharm. Pharmacol. 46:1994;938-950.
    • (1994) J. Pharm. Pharmacol. , vol.46 , pp. 938-950
    • Cornwell, P.A.1    Barry, B.W.2    Stoddart, C.P.3    Bouwstra, J.A.4
  • 42
    • 0028040472 scopus 로고
    • Characterization of low-temperature (i.e., <65°C) lipid transitions in human stratum corneum
    • Gay C.L., Guy R.H., Golden G.M., Mak V.H.W., Francoeur M.L. Characterization of low-temperature (i.e., <65°C) lipid transitions in human stratum corneum. J. Invest. Dermatol. 103:1994;233-239.
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 233-239
    • Gay, C.L.1    Guy, R.H.2    Golden, G.M.3    Mak, V.H.W.4    Francoeur, M.L.5
  • 44
    • 0027955474 scopus 로고
    • A domain mosaic model of the skin barrier
    • Forslind B. A domain mosaic model of the skin barrier. Acta Derm. Venereol. 74:1994;1-6.
    • (1994) Acta Derm. Venereol. , vol.74 , pp. 1-6
    • Forslind, B.1
  • 47
    • 0028299927 scopus 로고
    • Role of transepidermal and transfollicular routes in percutaneous absorption of steroids: In vitro studies on human skin
    • Hueber F., Schaefer H., Wepierre J. Role of transepidermal and transfollicular routes in percutaneous absorption of steroids: in vitro studies on human skin. Skin Pharmacol. 7:1994;237-244.
    • (1994) Skin Pharmacol. , vol.7 , pp. 237-244
    • Hueber, F.1    Schaefer, H.2    Wepierre, J.3
  • 48
    • 0002448680 scopus 로고
    • Mechanism of percutaneous absorption from physicochemical evidence
    • in: R.L. Bronaugh, H.I. Maibach (Eds.) Marcel Dekker, New York
    • G.L. Flynn, Mechanism of percutaneous absorption from physicochemical evidence, in: R.L. Bronaugh, H.I. Maibach (Eds.), Percutaneous Absorption: Mechanisms-Methodology-Drug Delivery, Marcel Dekker, New York, 1989, pp. 27-51.
    • (1989) Percutaneous Absorption: Mechanisms-Methodology-Drug Delivery , pp. 27-51
    • Flynn, G.L.1
  • 49
    • 0027290950 scopus 로고
    • Effect of receiver fluid pH on in vitro skin flux of weakly ionizable drugs
    • Kou J.H., Roy S.D., Du J., Fujiki J. Effect of receiver fluid pH on in vitro skin flux of weakly ionizable drugs. Pharm. Res. 10:1993;986-990.
    • (1993) Pharm. Res. , vol.10 , pp. 986-990
    • Kou, J.H.1    Roy, S.D.2    Du, J.3    Fujiki, J.4
  • 50
    • 0020608231 scopus 로고
    • Epidermal lipids, barrier function, and desquamation
    • Elias P.M. Epidermal lipids, barrier function, and desquamation. J. Invest. Dermatol. 80:1983;44s-49s.
    • (1983) J. Invest. Dermatol. , vol.80
    • Elias, P.M.1
  • 51
    • 0018383835 scopus 로고
    • Percutaneous absorption: In vivo experiments
    • Albery W.J., Hadgraft J. Percutaneous absorption: in vivo experiments. J. Pharm. Pharmacol. 31:1979;140-147.
    • (1979) J. Pharm. Pharmacol. , vol.31 , pp. 140-147
    • Albery, W.J.1    Hadgraft, J.2
  • 52
    • 0026606514 scopus 로고
    • Predicting skin permeability
    • Potts R.O., Guy R.H. Predicting skin permeability. Pharm. Res. 9:1992;663-669.
    • (1992) Pharm. Res. , vol.9 , pp. 663-669
    • Potts, R.O.1    Guy, R.H.2
  • 53
    • 0024216417 scopus 로고
    • Physicochemical aspects of percutaneous penetration and its enhancement
    • Guy R.H., Hadgraft J. Physicochemical aspects of percutaneous penetration and its enhancement. Pharm. Res. 5:1988;753-758.
    • (1988) Pharm. Res. , vol.5 , pp. 753-758
    • Guy, R.H.1    Hadgraft, J.2
  • 55
    • 0027742574 scopus 로고
    • Enhanced permeation and stratum corneum structural alterations in the presence of dithiothreitol
    • Goates C.Y., Knutson K. Enhanced permeation and stratum corneum structural alterations in the presence of dithiothreitol. Biochim. Biophys. Acta. 1153:1993;289-298.
    • (1993) Biochim. Biophys. Acta , vol.1153 , pp. 289-298
    • Goates, C.Y.1    Knutson, K.2
  • 57
    • 51249188620 scopus 로고
    • The movement of molecules across lipid membranes: A molecular theory
    • Träuble H. The movement of molecules across lipid membranes: a molecular theory. J. Membr. Biol. 4:1971;193-208.
    • (1971) J. Membr. Biol. , vol.4 , pp. 193-208
    • Träuble, H.1
  • 58
    • 0022728447 scopus 로고
    • Permeability of lipid bilayers to water and ionic solutes
    • Deamer D.W., Bramhall J. Permeability of lipid bilayers to water and ionic solutes. Chem. Phys. Lipids. 40:1986;167-188.
    • (1986) Chem. Phys. Lipids , vol.40 , pp. 167-188
    • Deamer, D.W.1    Bramhall, J.2
  • 61
    • 0025905320 scopus 로고
    • Evidence that oleic acid exists in a separate phase within stratum corneum lipids
    • Ongpipattanakul B., Burnette R.R., Potts R.O., Francoeur M.L. Evidence that oleic acid exists in a separate phase within stratum corneum lipids. Pharm. Res. 8:1991;350-354.
    • (1991) Pharm. Res. , vol.8 , pp. 350-354
    • Ongpipattanakul, B.1    Burnette, R.R.2    Potts, R.O.3    Francoeur, M.L.4
  • 62
    • 0025030097 scopus 로고
    • Oleic acid: Its effects on stratum corneum in relation to (trans)dermal drug delivery
    • Francoeur M.L., Golden G.M., Potts R.O. Oleic acid: its effects on stratum corneum in relation to (trans)dermal drug delivery. Pharm. Res. 7:1990;621-627.
    • (1990) Pharm. Res. , vol.7 , pp. 621-627
    • Francoeur, M.L.1    Golden, G.M.2    Potts, R.O.3
  • 63
    • 0000969569 scopus 로고
    • Penetration enhancers. Mode of action in human skin
    • in: B. Shroot, H. Schaefer (Eds.) Karger, Basel
    • B.W. Barry, Penetration enhancers. Mode of action in human skin, in: B. Shroot, H. Schaefer (Eds.), Pharmacology of the Skin, Karger, Basel, 1987, pp. 121-137.
    • (1987) Pharmacology of the Skin , pp. 121-137
    • Barry, B.W.1
  • 66
    • 0001923132 scopus 로고
    • Action of penetration enhancers on human stratum corneum as assessed by differential scanning calorimetry
    • in: R.L. Bronaugh, H.I. Maibach (Eds.) Marcel Dekker, New York
    • M. Goodman, B.W. Barry, Action of penetration enhancers on human stratum corneum as assessed by differential scanning calorimetry, in: R.L. Bronaugh, H.I. Maibach (Eds.), Percutaneous Absorption: Mechanisms-Methodology-Drug Delivery, Marcel Dekker, New York, 1989, pp. 567-593.
    • (1989) Percutaneous Absorption: Mechanisms-Methodology-Drug Delivery , pp. 567-593
    • Goodman, M.1    Barry, B.W.2
  • 67
    • 0029073932 scopus 로고
    • Effect of hydration upon the fluidity of intercellular membranes of stratum corneum: An EPR study
    • Alonso A., Meirelles N., Tabak M. Effect of hydration upon the fluidity of intercellular membranes of stratum corneum: an EPR study. Biochim. Biophys. Acta. 1237:1995;6-15.
    • (1995) Biochim. Biophys. Acta , vol.1237 , pp. 6-15
    • Alonso, A.1    Meirelles, N.2    Tabak, M.3
  • 69
    • 0025871483 scopus 로고
    • Does hydration affect intercellular lipid organization in the stratum corneum?
    • Mak V.H.W., Potts R.O., Guy R.H. Does hydration affect intercellular lipid organization in the stratum corneum? Pharm. Res. 8:1991;1064-1065.
    • (1991) Pharm. Res. , vol.8 , pp. 1064-1065
    • Mak, V.H.W.1    Potts, R.O.2    Guy, R.H.3
  • 70
    • 0002063313 scopus 로고    scopus 로고
    • The structure of hydrated human stratum corneum by freeze fracture electron microscopy
    • van Hal D., Jeremiasse F., Spies F., Junginger H., Bouwstra J. The structure of hydrated human stratum corneum by freeze fracture electron microscopy. I. Invest. Dermatol. 106:1996;89-95.
    • (1996) I. Invest. Dermatol. , vol.106 , pp. 89-95
    • Van Hal, D.1    Jeremiasse, F.2    Spies, F.3    Junginger, H.4    Bouwstra, J.5
  • 71
    • 0026798827 scopus 로고
    • The effects of ethanol on the transport of lipophilic and polar permeants across hairless mouse skin: Methods/validation of a novel approach
    • Ghanem A.H., Mahmoud H., Higuchi W.I., Liu P., Good W.R. The effects of ethanol on the transport of lipophilic and polar permeants across hairless mouse skin: Methods/validation of a novel approach. Int. J. Pharm. 78:1992;137-156.
    • (1992) Int. J. Pharm. , vol.78 , pp. 137-156
    • Ghanem, A.H.1    Mahmoud, H.2    Higuchi, W.I.3    Liu, P.4    Good, W.R.5
  • 72
    • 0027159046 scopus 로고
    • Fluorescence anisotropy studies on the interaction of the short chain n-alkanols with stratum corneum lipid liposomes (SCLL) and distearoylphosphatidylcholine (DSPC)/distearoylphosphatidic acid (DSPA) liposomes
    • Kim Y.-H., Higuchi W.I., Herron J.N., Abraham W. Fluorescence anisotropy studies on the interaction of the short chain n-alkanols with stratum corneum lipid liposomes (SCLL) and distearoylphosphatidylcholine (DSPC)/distearoylphosphatidic acid (DSPA) liposomes. Biochim. Biophys. Acta. 1148:1993;139-151.
    • (1993) Biochim. Biophys. Acta , vol.1148 , pp. 139-151
    • Kim, Y.-H.1    Higuchi, W.I.2    Herron, J.N.3    Abraham, W.4
  • 73
    • 0026497717 scopus 로고
    • Ethanol effects on the stratum corneum lipid phase behavior
    • Krill S.L., Knutson K., Higuchi W.I. Ethanol effects on the stratum corneum lipid phase behavior. Biochim. Biophys. Acta. 112:1992;273-280.
    • (1992) Biochim. Biophys. Acta , vol.112 , pp. 273-280
    • Krill, S.L.1    Knutson, K.2    Higuchi, W.I.3
  • 74
    • 0025785005 scopus 로고
    • Examination of the effect of ethanol on human stratum corneum in vivo using infrared spectroscopy
    • Bommannan D., Potts R.O., Guy R.H. Examination of the effect of ethanol on human stratum corneum in vivo using infrared spectroscopy. J. Control. Rel. 16:1991;299-304.
    • (1991) J. Control. Rel. , vol.16 , pp. 299-304
    • Bommannan, D.1    Potts, R.O.2    Guy, R.H.3
  • 75
    • 0025100879 scopus 로고
    • Solvent-mediated alterations of the stratum corneum
    • Knutson K., Krill S.L., Zhang J. Solvent-mediated alterations of the stratum corneum. J. Control. Rel. 11:1990;93-103.
    • (1990) J. Control. Rel. , vol.11 , pp. 93-103
    • Knutson, K.1    Krill, S.L.2    Zhang, J.3
  • 76
    • 0025032458 scopus 로고
    • Percutaneous absorption enhancement of an ionic molecule by ethanol-water systems in human skin
    • Kurihara-Bergstrom T., Knutson K., DeNoble L., Goates C.Y. Percutaneous absorption enhancement of an ionic molecule by ethanol-water systems in human skin. Pharm. Res. 7:1990;762-766.
    • (1990) Pharm. Res. , vol.7 , pp. 762-766
    • Kurihara-Bergstrom, T.1    Knutson, K.2    Denoble, L.3    Goates, C.Y.4
  • 77
    • 0025312282 scopus 로고
    • Mechanism of percutaneous penetration enhancement: Effect of n-alkanols on the permeability barrier of hairless mouse skin
    • Kai T., Mak V.H.W., Potts R.O., Guy R.H. Mechanism of percutaneous penetration enhancement: effect of n-alkanols on the permeability barrier of hairless mouse skin. J. Control. Rel. 12:1990;103-112.
    • (1990) J. Control. Rel. , vol.12 , pp. 103-112
    • Kai, T.1    Mak, V.H.W.2    Potts, R.O.3    Guy, R.H.4
  • 78
    • 0027988385 scopus 로고
    • Enhanced permeation of polar compounds through human epidermis. I. Permeability and membrane structural changes in the presence of short chain alcohols
    • Goates C.Y., Knutson K. Enhanced permeation of polar compounds through human epidermis. I. Permeability and membrane structural changes in the presence of short chain alcohols. Biochim. Biophys. Acta. 1195:1994;169-179.
    • (1994) Biochim. Biophys. Acta , vol.1195 , pp. 169-179
    • Goates, C.Y.1    Knutson, K.2
  • 79
    • 0028197118 scopus 로고
    • Selective extraction of stratum corneum components to probe mechanisms of enhanced percutaneous absorption
    • Oakeson R., Goates C., Knutson K. Selective extraction of stratum corneum components to probe mechanisms of enhanced percutaneous absorption. J. Control. Rel. 28:1994;277-278.
    • (1994) J. Control. Rel. , vol.28 , pp. 277-278
    • Oakeson, R.1    Goates, C.2    Knutson, K.3
  • 80
    • 0027972454 scopus 로고
    • Analysis of the combined effect of 1-menthol and ethanol as skin permeation enhancers based on a two-layer skin model
    • Kobayashi D., Matsuzawa T., Sugibayashi K., Morimoto Y., Kimura M. Analysis of the combined effect of 1-menthol and ethanol as skin permeation enhancers based on a two-layer skin model. Pharm. Res. 11:1994;96-103.
    • (1994) Pharm. Res. , vol.11 , pp. 96-103
    • Kobayashi, D.1    Matsuzawa, T.2    Sugibayashi, K.3    Morimoto, Y.4    Kimura, M.5
  • 81
    • 0028327365 scopus 로고
    • Macromolecular transport in and effective pore size of ethanol pretreated human epidermal membrane
    • Inamori T., Ghanem A.-H., Higuchi W., Srinivasan V. Macromolecular transport in and effective pore size of ethanol pretreated human epidermal membrane. Int. J. Pharm. 105:1994;113-123.
    • (1994) Int. J. Pharm. , vol.105 , pp. 113-123
    • Inamori, T.1    Ghanem, A.-H.2    Higuchi, W.3    Srinivasan, V.4
  • 82
    • 0028101808 scopus 로고
    • Hindered diffusion of polar molecules through and effective pore radii estimates of intact and ethanol treated human epidermal membrane
    • Peck K.D., Ghanem A.-H., Higuchi W.I. Hindered diffusion of polar molecules through and effective pore radii estimates of intact and ethanol treated human epidermal membrane. Pharm. Res. 11:1994;1306-1314.
    • (1994) Pharm. Res. , vol.11 , pp. 1306-1314
    • Peck, K.D.1    Ghanem, A.-H.2    Higuchi, W.I.3
  • 83
    • 0030598276 scopus 로고    scopus 로고
    • Changes in lipid organisation of the skin barrier by N-alkyl-azocycloheptanones: A visualisation and X-ray diffraction study
    • Bouwstra J., Salomons-de Vries M., van den Bergh B., Gooris G. Changes in lipid organisation of the skin barrier by N-alkyl-azocycloheptanones: a visualisation and X-ray diffraction study. Int. J. Pharm. 144:1996;81-89.
    • (1996) Int. J. Pharm. , vol.144 , pp. 81-89
    • Bouwstra, J.1    Salomons-De Vries, M.2    Van Den Bergh, B.3    Gooris, G.4
  • 84
    • 0023001444 scopus 로고
    • Enhancement of naloxone penetration through human skin in vitro using fatty acids, fatty alcohols, surfactants, sulfoxides and amides
    • Aungst B.J., Rogers N.J., Shefter E. Enhancement of naloxone penetration through human skin in vitro using fatty acids, fatty alcohols, surfactants, sulfoxides and amides. Int. J. Pharm. 33:1986;225-234.
    • (1986) Int. J. Pharm. , vol.33 , pp. 225-234
    • Aungst, B.J.1    Rogers, N.J.2    Shefter, E.3
  • 85
    • 0024639484 scopus 로고
    • Structure/effect studies of fatty acid isomers as skin penetration enhancers and skin irritants
    • Aungst B.J. Structure/effect studies of fatty acid isomers as skin penetration enhancers and skin irritants. Pharm. Res. 6:1989;244-247.
    • (1989) Pharm. Res. , vol.6 , pp. 244-247
    • Aungst, B.J.1
  • 86
    • 0021182767 scopus 로고
    • Increased skin permeability for lipophilic molecules
    • Cooper E.R. Increased skin permeability for lipophilic molecules. J. Pharm. Sci. 73:1984;1153-1156.
    • (1984) J. Pharm. Sci. , vol.73 , pp. 1153-1156
    • Cooper, E.R.1
  • 87
    • 0023785868 scopus 로고
    • Effect of primary alcohols on percutaneous absorption
    • Tsuzuki N., Wong O., Higuchi T. Effect of primary alcohols on percutaneous absorption. Int. J. Pharm. 46:1988;19-23.
    • (1988) Int. J. Pharm. , vol.46 , pp. 19-23
    • Tsuzuki, N.1    Wong, O.2    Higuchi, T.3
  • 88
    • 0025953864 scopus 로고
    • Kinetics, ultrastructural aspects and molecular modelling of transdermal peptide flux enhancement by Nalkylazacycloheptanones
    • Hoogstraate A.J., Verhoef J., Brussee J., IJzerman A.P., Spies F., Bodde H.E. Kinetics, ultrastructural aspects and molecular modelling of transdermal peptide flux enhancement by Nalkylazacycloheptanones. Int. J. Pharm. 76:1991;37-47.
    • (1991) Int. J. Pharm. , vol.76 , pp. 37-47
    • Hoogstraate, A.J.1    Verhoef, J.2    Brussee, J.3    Ijzerman, A.P.4    Spies, F.5    Bodde, H.E.6
  • 89
    • 0026060785 scopus 로고
    • Effect of 1-alkyl- Or 1-alkenylazacycloalkanone derivatives on the penetration of drugs with different lipophilicities through guinea pig skin
    • Okamoto H., Hashida M., Sezaki H. Effect of 1-alkyl- or 1-alkenylazacycloalkanone derivatives on the penetration of drugs with different lipophilicities through guinea pig skin. J. Pharm. Sci. 80:1991;39-45.
    • (1991) J. Pharm. Sci. , vol.80 , pp. 39-45
    • Okamoto, H.1    Hashida, M.2    Sezaki, H.3
  • 90
    • 0023107312 scopus 로고
    • Role of stratum corneum lipid fluidity in transdermal drug flux
    • Golden G.M., McKie J.E., Potts R.O. Role of stratum corneum lipid fluidity in transdermal drug flux. J. Pharm. Sci. 76:1987;25-28.
    • (1987) J. Pharm. Sci. , vol.76 , pp. 25-28
    • Golden, G.M.1    McKie, J.E.2    Potts, R.O.3
  • 91
    • 0023680522 scopus 로고
    • Action of penetration enhancers on human skin as assessed by the permeation of model drugs 5-fluorouracil and estradiol. I. Infinite dose technique.
    • Goodman M., Barry B.W. Action of penetration enhancers on human skin as assessed by the permeation of model drugs 5-fluorouracil and estradiol. I. Infinite dose technique. J. Invest. Dermatol. 91:1988;323-327.
    • (1988) J. Invest. Dermatol. , vol.91 , pp. 323-327
    • Goodman, M.1    Barry, B.W.2
  • 92
    • 0026014988 scopus 로고
    • Effect of penetration enhancers on the phase transition of multilamellar liposomes of dipalmitoylphosphatidylcholine. A study by differential scanning calorimetry
    • Rolland A., Brzokewicz A., Shroot B., Jamoulle J.-C. Effect of penetration enhancers on the phase transition of multilamellar liposomes of dipalmitoylphosphatidylcholine. A study by differential scanning calorimetry. Int. J. Pharm. 76:1991;217-224.
    • (1991) Int. J. Pharm. , vol.76 , pp. 217-224
    • Rolland, A.1    Brzokewicz, A.2    Shroot, B.3    Jamoulle, J.-C.4
  • 93
    • 0025047520 scopus 로고
    • Percutaneous penetration enhancement in vivo measured by attenuated total reflectance infrared spectroscopy
    • Mak V.H.W., Potts R.O., Guy R.H. Percutaneous penetration enhancement in vivo measured by attenuated total reflectance infrared spectroscopy. Pharm. Res. 7:1990;835-841.
    • (1990) Pharm. Res. , vol.7 , pp. 835-841
    • Mak, V.H.W.1    Potts, R.O.2    Guy, R.H.3
  • 94
    • 0025346850 scopus 로고
    • Oleic acid concentration and effect in human stratum corneum: Noninvasive determination by attenuated total reflectance infrared spectroscopy in vivo
    • Mak V.H.W., Potts R.O., Guy R.H. Oleic acid concentration and effect in human stratum corneum: noninvasive determination by attenuated total reflectance infrared spectroscopy in vivo. J. Control. Rel. 12:1990;67-75.
    • (1990) J. Control. Rel. , vol.12 , pp. 67-75
    • Mak, V.H.W.1    Potts, R.O.2    Guy, R.H.3
  • 95
    • 0027977918 scopus 로고
    • Effect of oleic acid on human epidermis: Fluorescence spectroscopic investigation
    • Garrison M.D., Doh L.M., Potts R.O., Abraham W. Effect of oleic acid on human epidermis: fluorescence spectroscopic investigation. J. Control. Rel. 31:1994;263-269.
    • (1994) J. Control. Rel. , vol.31 , pp. 263-269
    • Garrison, M.D.1    Doh, L.M.2    Potts, R.O.3    Abraham, W.4
  • 96
    • 0025331544 scopus 로고
    • Transdermal drug delivery: Efficacy and potential applications of the penetration enhancer Azone
    • Wiechers J.W., deZeeuw R.A. Transdermal drug delivery: efficacy and potential applications of the penetration enhancer Azone. Drug Design Deliv. 6:1990;87-100.
    • (1990) Drug Design Deliv. , vol.6 , pp. 87-100
    • Wiechers, J.W.1    Dezeeuw, R.A.2
  • 97
    • 0020564396 scopus 로고
    • Azone: A new non-toxic enhancer of cutaneous penetration
    • Stoughton R.B., McClure W.O. Azone: A new non-toxic enhancer of cutaneous penetration. Drug Dev. Ind. Pharm. 9:1983;725-744.
    • (1983) Drug Dev. Ind. Pharm. , vol.9 , pp. 725-744
    • Stoughton, R.B.1    McClure, W.O.2
  • 98
    • 0019940117 scopus 로고
    • Enhanced percutaneous penetration with 1-dodecylazacycloheptan-2-one
    • Stoughton R.B. Enhanced percutaneous penetration with 1-dodecylazacycloheptan-2-one. Arch. Dermatol. 118:1982;474-477.
    • (1982) Arch. Dermatol. , vol.118 , pp. 474-477
    • Stoughton, R.B.1
  • 99
    • 0025602796 scopus 로고
    • Mixed monolayers of dipalmitoylphopsphatidylcholine with Azone or oleic acid at the air-water interface
    • Lewis D., Hadgraft J. Mixed monolayers of dipalmitoylphopsphatidylcholine with Azone or oleic acid at the air-water interface. Int. J. Pharm. 65:1990;211-218.
    • (1990) Int. J. Pharm. , vol.65 , pp. 211-218
    • Lewis, D.1    Hadgraft, J.2
  • 101
    • 0027506791 scopus 로고
    • An X-ray diffraction study of some model stratum corneum lipids containing Azone and dodecyl-L-pyroglutamate
    • Schückler F., Bouwstra J.A., Gooris G.S., Lee G. An X-ray diffraction study of some model stratum corneum lipids containing Azone and dodecyl-L-pyroglutamate. J. Control. Rel. 23:1993;27-36.
    • (1993) J. Control. Rel. , vol.23 , pp. 27-36
    • Schückler, F.1    Bouwstra, J.A.2    Gooris, G.S.3    Lee, G.4
  • 104
    • 0000850743 scopus 로고
    • The epidermal cell periphery
    • in: L.A. Goldsmith (Ed.) Oxford University Press, New York
    • L.A. Goldsmith, The epidermal cell periphery, in: L.A. Goldsmith (Ed.), The Biochemistry and Physiology of the Skin, Oxford University Press, New York, 1983, pp. 184-196.
    • (1983) The Biochemistry and Physiology of the Skin , pp. 184-196
    • Goldsmith, L.A.1
  • 105
    • 0000850743 scopus 로고
    • Postranslational modification of proteins in keratinized tissue
    • in: L.A. Goldsmith (Ed.) Oxford University Press, New York
    • L.A. Goldsmith, Postranslational modification of proteins in keratinized tissue, in: L.A. Goldsmith (Ed.), The Biochemistry and Physiology of the Skin, Oxford University Press, New York, 1983, pp. 197-199.
    • (1983) The Biochemistry and Physiology of the Skin , pp. 197-199
    • Goldsmith, L.A.1
  • 106
    • 0017707982 scopus 로고
    • Protein conformational changes induced in human stratum corneum by organic sulfoxides: An infrared spectroscopic investigation
    • Oertel R.P. Protein conformational changes induced in human stratum corneum by organic sulfoxides: an infrared spectroscopic investigation. Biopolymers. 16:1977;2329-2345.
    • (1977) Biopolymers , vol.16 , pp. 2329-2345
    • Oertel, R.P.1


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