Sustained phenotypic reversion of junctional epidermolysis bullosa dog keratinocytes: Establishment of an immunocompetent animal model for cutaneous gene therapy

Biochemical and Biophysical Research Communications

Volumn 339, Issue 3, 2006, Pages 769-778

  Spirito, Flavia ^a   Capt, Annabelle ^a   Rio, Marcela Del ^c   Larcher, Fernando ^c   Guaguere, Eric ^d   Danos, Olivier ^b   Meneguzzi, Guerrino ^a  

^a INSERM   (France)

^b GÉNÉTHON   (France)

^c CIEMAT   (Spain)

^d CLINIQUE VÉTÉRINAIRE   (France)

Author keywords

Animal model; Cutaneous disorders; Dog; Epidermolysis bullosa; Gene therapy; Gene transfer; Keratinocyte; Laminin 5; Retroviral vector; Skin

Indexed keywords

KALININ; RECOMBINANT LAMININ ALPHA3; RECOMBINANT PROTEIN; RETROVIRUS VECTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL BASED GENE THERAPY; CELL DIFFERENTIATION; CONTROLLED STUDY; DOG; EPIDERMOLYSIS BULLOSA; EXTRACELLULAR MATRIX; FEASIBILITY STUDY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE MUTATION; GENE TRANSFER; IMMUNOCOMPETENCE; KERATINOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SECRETION; SAFETY; SKIN DISEASE; TRANSGENE; WILD TYPE;

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOGS; EPIDERMOLYSIS BULLOSA; GENE TARGETING; GENE THERAPY; IMMUNOCOMPETENCE; KERATINOCYTES; LAMININ; MICE; RECOMBINANT PROTEINS; SKIN; TREATMENT OUTCOME;

ANIMALIA; CANIS FAMILIARIS;

EID: 28844454528     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.10.216     Document Type: Article

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