Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin

Cellular and Molecular Life Sciences

Volumn 65, Issue 3, 2008, Pages 455-476

  Lubelski, J ^a   Rink, R ^a   Khusainov, R ^a   Moll, G N ^a   Kuipers, O P ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Biosynthesis; Cyclization; Dehydration; Mode of action; Nisin; Protein engineering; Therapeutical peptides; Thioether containing peptides

Indexed keywords

HYDROLYASE; LANTHIONINE; LANTIBIOTIC; NISIN; SYNTHETASE;

AUTOREGULATION; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; CYCLIZATION; CYTOPLASM; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE EXPRESSION; GENE FUNCTION; GENETIC TRANSCRIPTION; IMMUNE SYSTEM; IMMUNOREGULATION; IN VITRO STUDY; NONHUMAN; PROTEIN ENGINEERING; PROTEIN FAMILY; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REVIEW;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BACTERIOCINS; HYDRO-LYASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; NISIN; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 38949166717     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-007-7171-2     Document Type: Review

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