Synthesis and biological activities of cyclic lanthionine enkephalin analogues: δ-opioid receptor selective ligands

Journal of Medicinal Chemistry

Volumn 45, Issue 17, 2002, Pages 3746-3754

  Rew, Yosup ^a   Malkmus, Shelle ^a   Svensson, Camilla ^a   Yaksh, Tony L ^a   Chung, Nga N ^b   Schiller, Peter W ^b   Cassel, Joel A ^c   DeHaven, Robert N ^c   Goodman, Murray ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^c ADOLOR CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN DERIVATIVE; KAPPA OPIATE RECEPTOR; LANTHIONINE; MU OPIATE RECEPTOR; OPIATE AGONIST; SIGMA OPIATE RECEPTOR;

AMINO ACID COMPOSITION; ANIMAL CELL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DOSE RESPONSE; DRUG ACTIVITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ALANINE; ANALGESICS; ANIMALS; CHO CELLS; CRICETINAE; ENKEPHALINS; ESCAPE REACTION; HUMANS; ILEUM; INJECTIONS, SPINAL; MALE; MICE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; SULFIDES; SWINE; VAS DEFERENS;

EID: 0037103136     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020108k     Document Type: Article

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