Identification of essential catalytic residues of the cyclase NisC involved in the biosynthesis of nisin

Journal of Biological Chemistry

Volumn 282, Issue 29, 2007, Pages 21169-21175

  Li, Bo ^a   Van Der Donk, Wilfred A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC RESIDUES; MUTANTS; NISIN; X-RAY CRYSTAL STRUCTURE;

AMINO ACIDS; BIOSYNTHESIS; CATALYST ACTIVITY; CYCLIZATION; LIGANDS; MUTAGENESIS; NUCLEOPHILES;

ENZYMES;

ALANINE; ARGININE; ASPARTIC ACID; CYSTEINE; ENZYME; HISTIDINE; LIGAND; MUTANT PROTEIN; NISA PROTEIN; NISC PROTEIN; NISIN; PROTEIN; TYROSINE; UNCLASSIFIED DRUG; ZINC;

AMINO ACID SUBSTITUTION; ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING AFFINITY; BIOSYNTHESIS; CATALYSIS; CYCLIZATION; ENZYME ACTIVITY; MUTANT; MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; ESCHERICHIA COLI PROTEINS; INTRAMOLECULAR LYASES; LIGANDS; MODELS, CHEMICAL; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NISIN; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; ZINC;

EID: 34547137156     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M701802200     Document Type: Article

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