Molecular and genetic characterization of a novel nisin variant produced by Streptococcus uberis

Applied and Environmental Microbiology

Volumn 72, Issue 2, 2006, Pages 1148-1156

  Wirawan, Ruth E ^a   Klesse, Nikolai A ^a   Jack, Ralph W ^a   Tagg, John R ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOLOGY; BIOSYNTHESIS;

BOVINE MASTITIS; IMMUNITY PEPTIDES; STREPTOCOCCUS UBERIS;

POLYPEPTIDES;

LANTIBIOTIC; NISIN; NISIN A; NISIN U; UNCLASSIFIED DRUG;

GENE EXPRESSION;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACTERIAL STRAIN; CATTLE DISEASE; CONTROLLED STUDY; CROSS RESISTANCE; GENE LOCUS; GENETIC ANALYSIS; IMMUNITY; LACTOCOCCUS LACTIS; MOLECULAR BIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PROTEIN FAMILY; PROTEIN VARIANT; SEQUENCE HOMOLOGY; STREPTOCOCCUS UBERIS; STRUCTURAL GENE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATTLE; DNA, BACTERIAL; FEMALE; GENES, BACTERIAL; MASTITIS, BOVINE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NISIN; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOCOCCUS; VARIATION (GENETICS);

BACTERIA (MICROORGANISMS); BOS TAURUS; BOVINAE; LACTOCOCCUS LACTIS; STREPTOCOCCUS UBERIS;

EID: 33144466523     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.72.2.1148-1156.2006     Document Type: Article

References (45)

1. Altschul, S. F., T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller, and D. J. Lipman. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
2. Banerjee, S., and J. N. Hansen. 1988. Structure and expression of a gene encoding the precursor of subtilin, a small protein antibiotic. J. Biol. Chem. 263:9508-9514.
3. Bierbaum, G., F. Gotz, A. Peschel, T. Kupke, M. van de Kamp, and H.-G. Sahl. 1996. The biosynthesis of the lantibiotics epidermin, gallidermin, Pep5 and epilancin K7. Antonie Leeuwenhoek 69:119-127.
4. Blowey, R., and P. Edmondson. 1995. Mastitis control in dairy herds: an illustrated and practical guide. Farming Press Books, Ipswich, United Kingdom.
5. Broadbent, J. R., C. Chou, K. Gillies, and J. K. Kondo. 1989. Nisin inhibits several gram-positive, mastitis-causing pathogens. J. Dairy Sci. 72:3342-3345.
6. Buddle, B. M., J. R. Tagg, and M. J. Ralston. 1988. Use of an inhibitor typing scheme to study the epidemiology of Streptococcus uberis mastitis. N. Z. Vet. J. 36:115-119.
7. Chan, W. C., B. W. Bycroft, L.-Y. Lian, and G. C. K. Roberts. 1989. Isolation and characterisation of two degradation products derived from the peptide antibiotic nisin. FEBS Lett. 252:29-36.
8. Chatterjee, C., M. Paul, L. Xie, and W. A. van der Donk. 2005. Biosynthesis and mode of action of lantibiotics. Chem. Rev. 105:633-684.
9. de Vos, W. M., O. P. Kuipers, J. R. van der Meer, and R. J. Siezen. 1995. Maturation pathway of nisin and other lantibiotics: posttranslationally modified antimicrobial peptides exported by gram-positive bacteria. Mol. Microbiol. 17:427-437.
10. Guder, A., I. Wiedemann, and H.-G. Sahl. 2000. Post-translationally modified bacteriocins: the lantibiotics. Biopolymers 55:62-73.
11. Hardie, J. M. 1986. Genus Streptococcus Rosenbach 1884, 22AL, p. 1043-1071. In P. H. A. Sneath, N. S. Mair, M. E. Sharpe, and J. G. Holt (ed.), Bergey's manual of systematic bacteriology, vol. 2. The Williams & Wilkins Co., Baltimore, Md.
12. Heidrich, C., U. Pag, M. Josten, J. Metzger, R. W. Jack, G. Bierbaum, G. Jung, and H.-G. Sahl. 1998. Isolation, characterization, and heterologous expression of the novel lantibiotic epicidin 280 and analysis of its biosynthetic gene cluster. Appl. Environ. Microbiol. 64:3140-3146.
13. Hubbard, M. J., N. J. McHugh, and D. L. Carne. 2000. Isolation of ERp29, a novel endoplasmic reticulum protein, from rat enamel cells. Eur. J. Biochem. 267:1945-1956.
14. Jack, R. W., and J. R. Tagg. 1991. Isolation and partial structure of streptococcin A-FF22, p. 171-179 In G. Jung and H.-G. Sahl (ed.), Nisin and novel lantibiotics. Escom Publishers, Leiden, The Netherlands.
15. Jayarao, B. M., S. P. Oliver, J. R. Tagg, and K. R. Matthews. 1991. Genotypic and phenotypic analysis of Streptococcus uberis isolated from bovine mammary secretions. Epidemiol. Infect. 107:543-555.
16. Kleerebezem, M. 2004. Quorum sensing control of lantibiotic production: nisin and subtilin autoregulate their own biosynthesis. Peptides 25:1405-1414.
17. Klein, C., and K. D. Entian. 1994. Genes involved in self-protection against the lantibiotic subtilin produced by Bacillus subtilis ATCC 6633. Appl. Environ. Microbiol. 60:2793-2801.
18. Klesse, N. A. 2001. Purification and partial characterisation of a novel bacteriocin produced by Streptococcus uberis strain ATCC 27958. MSc, thesis. University of Otago, Dunedin, New Zealand.
19. Kuipers, O. P., M. M. Beerthuyzen, P. G. de Ruyter, E. J. Luesink, and W. M. de Vos. 1995. Autoregulation of nisin biosynthesis in Lactococcus lactis by signal transduction. J. Biol. Chem. 270:27299-27304.
20. Kuipers, O. P., M. M. Beerthuyzen, R. J. Siezen, and W. M. De Vos. 1993. Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity. Eur. J. Biochem. 216:281-291.
21. Leigh, J. A. 1999. Streptococcus uberis: a permanent barrier to the control of bovine mastitis? Vet. J. 157:225-238.
22. McAuliffe, O., R. P. Ross, and C. Hill. 2001. Lantibiotics: structure, biosynthesis and mode of action. FEMS Microbiol. Rev. 25:285-308.
23. Meyer, H. E., M. Heber, B. Eisermann, H. Korte, J. W. Metzger, and G. Jung. 1994. Sequence analysis of lantibiotics: chemical derivatization procedures allow a fast access to complete Edman degradation. Anal. Biochem. 223:185-190.
24. Mota-Meira, M., C. Lacroix, G. LaPointe, and M. C. Lavoie. 1997. Purification and structure of mutacin B-Ny266: a new lantibiotic produced by Streptococcus mutans. FEBS Lett. 410:275-279.
25. Mulders, J. W., I. J. Boerrigter, H. S. Rollema, R. J. Siezen, and W. M. de Vos. 1991. Identification and characterization of the lantibiotic nisin Z, a natural nisin variant. Eur. J. Biochem. 201:581-584.
26. Nes, I. F., and J. R. Tagg. 1996. Novel lantibiotics and their pre-peptides. Antonie Leeuwenhoek 69:89-97.
27. Ra, R., M. M. Beerthuyzen, W. M. de Vos, P. E. Saris, and O. P. Kuipers. 1999. Effects of gene disruptions in the nisin gene cluster of Lactococcus lactis on nisin production and producer immunity. Microbiology 145:1227-1233.
28. Rauch, P. J., M. M. Beerthuyzen, and W. M. de Vos. 1994. Distribution and evolution of nisin-sucrose elements in Lactococcus lactis. Appl. Environ. Microbiol. 60:1798-1804.
29. Rollema, H. S., J. W. Metzger, P. Both, O. P. Kuipers, and R. J. Siezen. 1996. Structure and biological activity of chemically modified nisin A species. Eur. J. Biochem. 241:716-722.
30. Ryan, M. P., W. J. Meaney, R. P. Ross, and C. Hill. 1998. Evaluation of lacticin 3147 and a teat seal containing this bacteriocin for inhibition of mastitis pathogens. Appl. Environ. Microbiol. 64:2287-2290.
31. Sahl, H.-G., and G. Bierbaum. 1998. Lantibiotics: biosynthesis and biological activities of uniquely modified peptides from gram-positive bacteria. Annu. Rev. Microbiol. 52:41-79.
32. Sahl, H.-G., R. W. Jack, and G. Bierbaum. 1995. Biosynthesis and biological activities of lantibiotics with unique posttranslational modifications. Eur. J. Biochem. 230:827-853.
33. Sambrook, J., and D. W. Russell. 2001. Molecular cloning: a laboratory manual, 3rd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N,Y.
34. Schnell, N., K. D. Entian, U. Schneider, F. Gotz, H. Zahner, R. Kellner, and G. Jung. 1988. Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings. Nature 333:276-278.
35. Siegers, K., and K. D. Entian. 1995. Genes involved in immunity to the lantibiotic nisin produced by Lactococcus lactis 6F3. Appl. Environ. Microbiol. 61:1082-1089.
36. Siezen, R. J., O. P. Kuipers, and W. M. de Vos. 1996. Comparison of lantibiotic gene clusters and encoded proteins. Antonie Leeuwenhoek 69: 171-184.
37. Steen, M. T., Y. J. Chung, and J. N. Hansen. 1991. Characterization of the nisin gene as part of a polycistronic operon in the chromosome of Lactococcus lactis ATCC 11454. Appl. Environ. Microbiol. 57:1181-1188.
38. Tagg, J. R., and L. V. Bannister. 1979. "Fingerprinting" beta-hemolytic streptococci by their production of and sensitivity to bacteriocin-like inhibitors. J. Med. Microbiol. 12:397-411.
39. Tagg, J. R., and L. G. Vugler. 1986. An inhibitor typing scheme for Streptococcus uberis. J. Dairy Res. 53:451-456.
40. Van de Ven, F. J., H. W. Van den Hooven, R. N. Konings, and C. W. Hilbers. 1991. NMR studies of lantibiotics. The structure of nisin in aqueous solution. Eur. J. Biochem. 202:1181-1188.
41. van der Meer, J. R., J. Polman, M. M. Beerthuyzen, R. J. Siezen, O. P. Kuipers, and W. M. De Vos. 1993. Characterization of the Lactococcus lactis nisin A operon genes nisP, encoding a subtilisin-like serine protease involved in precursor processing, and nisR, encoding a regulatory protein involved in nisin biosynthesis. J. Bacteriol. 175:2578-2588.
42. Walk, T. B., R. Sussmuth, C. Kempter, V. Gnau, R. W. Jack, and G. Jung. 1999. Identification of unusual amino acids in peptides using automated sequential Edman degradation coupled to direct detection by electrospray- ionization mass spectrometry. Biopolymers 49:329-340.
43. Wescombe, P. A., and J. R. Tagg. 2003. Purification and characterization of streptin, a type A1 lantibiotic produced by Streptococcus pyogenes. Appl. Environ. Microbiol. 69:2737-2747.
44. Wiedemann, I., E. Breukink, C. van Kraaij, O. P. Kuipers, G. Bierbaum, B. de Kruijff, and H.-G. Sahl. 2001. Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity. J. Biol Chem. 276:1772-1779.
45. Zendo, T., M. Fukao, K. Ueda, T. Higuchi, J. Nakayama, and K. Sonomoto. 2003. Identification of the lantibiotic nisin Q, a new natural nisin variant produced by Lactococcus lactis 61-14 isolated from a river in Japan. Biosci. Biotechnol. Biochem. 67:1616-1619.