메뉴 건너뛰기




Volumn 2, Issue 6, 2007, Pages 655-666

Novel targets for antibiotics in Staphylococcus aureus

Author keywords

Antibiotic resistance; Gram positive pathogens; Immunotherapy; MRSA; New targets; Novel antibacterials; Staphylococcus areus

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; ADHESIN; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; CERULENIN; DALBAVANCIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A; DNA TOPOISOMERASE IV; ENDOPEPTIDASE CLP; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADH); FTSZ PROTEIN; GENE PRODUCT; ISONIAZID; N [1 TERT BUTYL 2 OXO 2 [4 (2 THIAZOLYLMETHYL) 1 PIPERAZINYL]ETHYL] 3 CYCLOPENTYL 2 (N FORMYL N HYDROXYAMINOMETHYL)PROPIONAMIDE; NEW DRUG; ORITAVANCIN; PEPTIDE DEFORMYLASE; PEPTIDE DEFORMYLASE INHIBITOR; PEPTIDOGLYCAN GLYCOSYLTRANSFERASE; PLATENCIN; PLATENSIMYCIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; STAPHYLOCOCCUS VACCINE; TEICHOIC ACID; THIOREDOXIN; THIOREDOXIN REDUCTASE; TRICLOSAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; VIRIDITOXIN;

EID: 37549061026     PISSN: 17460913     EISSN: None     Source Type: Journal    
DOI: 10.2217/17460913.2.6.655     Document Type: Review
Times cited : (24)

References (102)
  • 1
    • 9644295892 scopus 로고    scopus 로고
    • System Report, data summary from January 1992 through June 2004, issued October 2004
    • National Nosocomial Infections Surveillance NNIS
    • National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am. J. Infect. Control 32, 470-485 (2004).
    • (2004) Am. J. Infect. Control , vol.32 , pp. 470-485
  • 2
    • 4444271222 scopus 로고    scopus 로고
    • Methicillin-resistant Staphylococcus aureus in Europe, 1999-2002
    • Tiemersma EW, Bronzwaer SL, Lyytikainen O et al.: Methicillin-resistant Staphylococcus aureus in Europe, 1999-2002. Emerg. Infect. Dis. 10, 1627-1634 (2004).
    • (2004) Emerg. Infect. Dis , vol.10 , pp. 1627-1634
    • Tiemersma, E.W.1    Bronzwaer, S.L.2    Lyytikainen, O.3
  • 3
    • 33747343208 scopus 로고    scopus 로고
    • Methicillin-resistant S. aureus infections among patients in the emergency department
    • Moran GJ, Krishnadasan A, Gorwitz RJ et al.: Methicillin-resistant S. aureus infections among patients in the emergency department. N. Engl. J. Med. 355, 666-674 (2006).
    • (2006) N. Engl. J. Med , vol.355 , pp. 666-674
    • Moran, G.J.1    Krishnadasan, A.2    Gorwitz, R.J.3
  • 4
    • 0035928419 scopus 로고    scopus 로고
    • Linezolid resistance in a clinical isolate of Staphylococcus aureus
    • Tsiodras S, Gold HS, Sakoulas G et al.: Linezolid resistance in a clinical isolate of Staphylococcus aureus. Lancet 358, 207-208 (2001).
    • (2001) Lancet , vol.358 , pp. 207-208
    • Tsiodras, S.1    Gold, H.S.2    Sakoulas, G.3
  • 5
    • 0344827209 scopus 로고    scopus 로고
    • Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus
    • Weigel LM, Clewell DB, Gill SR et al.: Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus. Science 302, 569-1571 (2003).
    • (2003) Science , vol.302 , pp. 569-1571
    • Weigel, L.M.1    Clewell, D.B.2    Gill, S.R.3
  • 6
    • 9144264415 scopus 로고    scopus 로고
    • Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania
    • Tenover FC, Weigel LM, Appelbaum PC et al.: Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania. Antimicrob. Agents Chemother. 48, 275-280 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 275-280
    • Tenover, F.C.1    Weigel, L.M.2    Appelbaum, P.C.3
  • 8
    • 9244239747 scopus 로고    scopus 로고
    • Global transposon mutagenesis and essential gene analysis of Helicobacter pylori
    • Salama NR, Shepherd B, Falkow S: Global transposon mutagenesis and essential gene analysis of Helicobacter pylori. J. Bacteriol. 186, 7926-7935 (2004).
    • (2004) J. Bacteriol , vol.186 , pp. 7926-7935
    • Salama, N.R.1    Shepherd, B.2    Falkow, S.3
  • 9
    • 27244451533 scopus 로고    scopus 로고
    • Identification of essential genes in Streptococcus pneumoniae by allelic replacement mutagenesis
    • Song JH, Ko KS, Lee JY et al.: Identification of essential genes in Streptococcus pneumoniae by allelic replacement mutagenesis. Mol. Cells 19, 365-374 (2005).
    • (2005) Mol. Cells , vol.19 , pp. 365-374
    • Song, J.H.1    Ko, K.S.2    Lee, J.Y.3
  • 11
    • 0036271625 scopus 로고    scopus 로고
    • A genome-wide strategy for the identification of essential genes in Staphylococcus aureus
    • Forsyth RA, Haselbeck RJ, Ohlsen KL et al.: A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Mol. Microbiol. 43, 1387-1400 (2002).
    • (2002) Mol. Microbiol , vol.43 , pp. 1387-1400
    • Forsyth, R.A.1    Haselbeck, R.J.2    Ohlsen, K.L.3
  • 12
    • 0035929121 scopus 로고    scopus 로고
    • Identification of critical Staphylococcal genes using conditional phenotypes generated by antisense RNA
    • Ji Y, Zhang B, Van SF et al.: Identification of critical Staphylococcal genes using conditional phenotypes generated by antisense RNA. Science, 293, 2266-2269 (2001).
    • (2001) Science , vol.293 , pp. 2266-2269
    • Ji, Y.1    Zhang, B.2    Van, S.F.3
  • 13
    • 12144291286 scopus 로고    scopus 로고
    • A global approach to identify novel broad-spectrum antibacterial targets among proteins of unknown function
    • Zalacain M, Biswas S, Ingraham KA et al.: A global approach to identify novel broad-spectrum antibacterial targets among proteins of unknown function. J. Mol. Microbiol Biotechnol. 6, 109-126 (2003).
    • (2003) J. Mol. Microbiol Biotechnol , vol.6 , pp. 109-126
    • Zalacain, M.1    Biswas, S.2    Ingraham, K.A.3
  • 14
    • 0033927088 scopus 로고    scopus 로고
    • A method for demonstrating gene essentiality in Staphylococcus aureus
    • Jana M, Luong TT, Komatsuzawa H et al.: A method for demonstrating gene essentiality in Staphylococcus aureus. Plasmid 44, 100-104 (2000).
    • (2000) Plasmid , vol.44 , pp. 100-104
    • Jana, M.1    Luong, T.T.2    Komatsuzawa, H.3
  • 15
    • 0034687158 scopus 로고    scopus 로고
    • Regulated gene expression in Staphylococcus aureus for identifying conditional lethal phenotypes and antibiotic mode of action
    • Zhang L, Fan F, Palmer LM et al.: Regulated gene expression in Staphylococcus aureus for identifying conditional lethal phenotypes and antibiotic mode of action. Gene 255, 297-305 (2000).
    • (2000) Gene , vol.255 , pp. 297-305
    • Zhang, L.1    Fan, F.2    Palmer, L.M.3
  • 16
    • 0033529856 scopus 로고    scopus 로고
    • The essential Staphylococcus aureus gene fmhB is involved in the first step of peptidoglycan. pentaglycine interpeptide formation
    • Rohrer S, Ehlert K, Tschierske M, Labischinski H, Berger-Bachi B: The essential Staphylococcus aureus gene fmhB is involved in the first step of peptidoglycan. pentaglycine interpeptide formation. Proc. Natl Acad. Sci. USA, 96, 9351-9356 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 9351-9356
    • Rohrer, S.1    Ehlert, K.2    Tschierske, M.3    Labischinski, H.4    Berger-Bachi, B.5
  • 17
    • 0032728823 scopus 로고    scopus 로고
    • Regulated antisense RNA eliminates α-toxin virulence in Staphylococcus aureus infection
    • Ji Y, Marra A, Rosenberg M, Woodnutt G: Regulated antisense RNA eliminates α-toxin virulence in Staphylococcus aureus infection. J. Bacteriol. 181, 6585-6590 (2001).
    • (2001) J. Bacteriol , vol.181 , pp. 6585-6590
    • Ji, Y.1    Marra, A.2    Rosenberg, M.3    Woodnutt, G.4
  • 18
    • 37549072069 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of novel antibiotics targets from Staphylococcus aureus
    • In press
    • Streker K, Freiberg C, Brötz-Oesterhelt H et al.: In vitro and in vivo characterization of novel antibiotics targets from Staphylococcus aureus. Antimicrob. Agents Chemother. (2007) (In press).
    • (2007) Antimicrob. Agents Chemother
    • Streker, K.1    Freiberg, C.2    Brötz-Oesterhelt, H.3
  • 19
    • 33645030241 scopus 로고    scopus 로고
    • Robust Salmonella metabolism limits possibilities for new antimicrobials
    • Becker D, Selbach M, Rollenhagen C et al.: Robust Salmonella metabolism limits possibilities for new antimicrobials. Nature 440, 303-307 (2006).
    • (2006) Nature , vol.440 , pp. 303-307
    • Becker, D.1    Selbach, M.2    Rollenhagen, C.3
  • 20
    • 0242582382 scopus 로고    scopus 로고
    • Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics
    • Wang J, Galgoci A, Kodali S et al.: Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics. J. Biol. Chem. 278, 44424-44428 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 44424-44428
    • Wang, J.1    Galgoci, A.2    Kodali, S.3
  • 21
    • 4143110291 scopus 로고    scopus 로고
    • Targeting call division: Small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality
    • Margalit DN, Romberg L, Mets RB et al.: Targeting call division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality. Proc. Natl Acad. Sci. USA 101, 11821-11826 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 11821-11826
    • Margalit, D.N.1    Romberg, L.2    Mets, R.B.3
  • 22
    • 33644519967 scopus 로고    scopus 로고
    • The evolution of peptide deformylase as a target: Contribution of biochemistry, genetics and genomics
    • Yuan Z, White RJ: The evolution of peptide deformylase as a target: contribution of biochemistry, genetics and genomics. Biochem Pharmacol. 71, 1042-1047 (2006).
    • (2006) Biochem Pharmacol , vol.71 , pp. 1042-1047
    • Yuan, Z.1    White, R.J.2
  • 23
    • 24344497940 scopus 로고    scopus 로고
    • Therapeutic potential of peptide deformylase inhibitors
    • Chen D, Yuan Z: Therapeutic potential of peptide deformylase inhibitors. Expert Opin. Investig. Drugs 14, 1107-1116 (2005).
    • (2005) Expert Opin. Investig. Drugs , vol.14 , pp. 1107-1116
    • Chen, D.1    Yuan, Z.2
  • 24
    • 9644268250 scopus 로고    scopus 로고
    • Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics
    • Lee MD, She Y, Soskis MJ et al.: Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics. J. Clin. Invest. 114, 1107-1116 (2004).
    • (2004) J. Clin. Invest , vol.114 , pp. 1107-1116
    • Lee, M.D.1    She, Y.2    Soskis, M.J.3
  • 25
    • 6344280763 scopus 로고    scopus 로고
    • Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent
    • Yoon HJ, Kim HL, Lee SK et al.: Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent. Proteins 57, 639-642 (2004).
    • (2004) Proteins , vol.57 , pp. 639-642
    • Yoon, H.J.1    Kim, H.L.2    Lee, S.K.3
  • 26
    • 0036716795 scopus 로고    scopus 로고
    • N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity
    • Hackbarth CJ, Chen DZ, Lewis JG et al.: N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity. Antimicrob. Agents Chemother. 46, 2752-2764 (2002).
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 2752-2764
    • Hackbarth, C.J.1    Chen, D.Z.2    Lewis, J.G.3
  • 27
    • 9144268506 scopus 로고    scopus 로고
    • Peptide deformylase inhibitors as antibacterial agents: Identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach
    • Chen D, Hackbarth C, Ni ZJ et al.: Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach. Antimicrob. Agents Chemother. 48, 250-261 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 250-261
    • Chen, D.1    Hackbarth, C.2    Ni, Z.J.3
  • 28
    • 9644302493 scopus 로고    scopus 로고
    • Pharmacokinetics in animals and humans of a first-in-class peptide deformylase inhibitor
    • Ramanathan-Girish S, McColm J, Clements JM et al.: Pharmacokinetics in animals and humans of a first-in-class peptide deformylase inhibitor. Antimicrob. Agents Chemother. 48, 4835-4842 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 4835-4842
    • Ramanathan-Girish, S.1    McColm, J.2    Clements, J.M.3
  • 29
    • 33748783782 scopus 로고    scopus 로고
    • Identification of an essential gene of Listeria monocytogenes involved in teichoic acid biogenesis
    • Dubail I, Bigot A, Lazarevic V et al.: Identification of an essential gene of Listeria monocytogenes involved in teichoic acid biogenesis. J BacterioL 188, 6580--6591 (2006).
    • (2006) J BacterioL , vol.188 , pp. 6580-6591
    • Dubail, I.1    Bigot, A.2    Lazarevic, V.3
  • 30
    • 9244238685 scopus 로고    scopus 로고
    • Teichoic acid is an essential polymer in Bacillus subtilis that is functionally distinct from teichuronic acid
    • Bhavsar AP, Erdman LK, Schertzer JW, Brown ED: Teichoic acid is an essential polymer in Bacillus subtilis that is functionally distinct from teichuronic acid. J Bacteriol. 186, 7865-7873 (2004).
    • (2004) J Bacteriol , vol.186 , pp. 7865-7873
    • Bhavsar, A.P.1    Erdman, L.K.2    Schertzer, J.W.3    Brown, E.D.4
  • 31
    • 33751585943 scopus 로고    scopus 로고
    • Wall teichoic acid polymers are dispensable for cell viability in Bacillus subtilis
    • D'Elia MA, Millar KE, Beveridge TJ, Brown ED: Wall teichoic acid polymers are dispensable for cell viability in Bacillus subtilis. J. Bacteriol. 188, 8313-8316 (2006).
    • (2006) J. Bacteriol , vol.188 , pp. 8313-8316
    • D'Elia, M.A.1    Millar, K.E.2    Beveridge, T.J.3    Brown, E.D.4
  • 32
    • 33744969363 scopus 로고    scopus 로고
    • Lesions in teichoic acid biosynthesis in Staphylococcus aureus lead to a lethal gain of function in the otherwise dispensable pathway
    • D'Elia MA, Pereira MP Chung YS et al.: Lesions in teichoic acid biosynthesis in Staphylococcus aureus lead to a lethal gain of function in the otherwise dispensable pathway. J. Bacteriol. 188, 4183-4189 (2006).
    • (2006) J. Bacteriol , vol.188 , pp. 4183-4189
    • D'Elia, M.A.1    Pereira, M.P.2    Chung, Y.S.3
  • 33
    • 2342639647 scopus 로고    scopus 로고
    • Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections
    • Weidenmaier C, Kokai-Kun JF, Kristian SA et al.: Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections. Nat. Med. 10, 243-245 (2004).
    • (2004) Nat. Med , vol.10 , pp. 243-245
    • Weidenmaier, C.1    Kokai-Kun, J.F.2    Kristian, S.A.3
  • 34
    • 28444471602 scopus 로고    scopus 로고
    • DltABCD- and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model
    • Weidenmaier C, Peschel A, Kempf VA, Lucindo N, Yeaman MR, Bayer AS: DltABCD- and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model. Infect. Immun. 73, 8033-8038 (2005).
    • (2005) Infect. Immun , vol.73 , pp. 8033-8038
    • Weidenmaier, C.1    Peschel, A.2    Kempf, V.A.3    Lucindo, N.4    Yeaman, M.R.5    Bayer, A.S.6
  • 36
    • 0347915666 scopus 로고    scopus 로고
    • Transcriptional regulation of the Staphylococcus aureus thioredoxin and thioredoxin reductase genes in response to oxygen and disulfide stress
    • Uziel O, Borovok I, Schreiber R, Cohen G, Aharonowitz Y: Transcriptional regulation of the Staphylococcus aureus thioredoxin and thioredoxin reductase genes in response to oxygen and disulfide stress. J. Bacteriol. 186, 326-334 (2004).
    • (2004) J. Bacteriol , vol.186 , pp. 326-334
    • Uziel, O.1    Borovok, I.2    Schreiber, R.3    Cohen, G.4    Aharonowitz, Y.5
  • 37
    • 0029796449 scopus 로고    scopus 로고
    • Molecular cloning and expression of the spsB gene encoding an essential type I signal peptidase from Staphylococcus aureus
    • Cregg KM, Wilding I, Black MT: Molecular cloning and expression of the spsB gene encoding an essential type I signal peptidase from Staphylococcus aureus. J. Bacterial. 178, 5712-5718 (1996).
    • (1996) J. Bacterial , vol.178 , pp. 5712-5718
    • Cregg, K.M.1    Wilding, I.2    Black, M.T.3
  • 38
    • 9244241532 scopus 로고    scopus 로고
    • ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies
    • Garmory HS, Titball RW. ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies. Infect. Immun. 72, 6757-6763 (2004).
    • (2004) Infect. Immun , vol.72 , pp. 6757-6763
    • Garmory, H.S.1    Titball, R.W.2
  • 40
    • 27744473050 scopus 로고    scopus 로고
    • Sun J, Zheng L, Landwehr C, Yang J, Ji Y: Identification of a novel essential two-component signal transduction system, YhcSR, in Staphylococcus aureus. J. Bacteriol. 187, 7876-7880 (2005).
    • Sun J, Zheng L, Landwehr C, Yang J, Ji Y: Identification of a novel essential two-component signal transduction system, YhcSR, in Staphylococcus aureus. J. Bacteriol. 187, 7876-7880 (2005).
  • 41
    • 17144399138 scopus 로고    scopus 로고
    • Identification of an essential glycoprotease in Staphylococcus aureus
    • Zheng L, Yang J, Landwehr C, Fan F, Ji Y: Identification of an essential glycoprotease in Staphylococcus aureus. FEMS Microbiol. Lett. 245, 279-285 (2005).
    • (2005) FEMS Microbiol. Lett , vol.245 , pp. 279-285
    • Zheng, L.1    Yang, J.2    Landwehr, C.3    Fan, F.4    Ji, Y.5
  • 42
    • 1142298553 scopus 로고    scopus 로고
    • Identification of genes controlled by the essential YycG/YycF two-component system of Staphylococcus aureus
    • Dubrac S, Msadek T: Identification of genes controlled by the essential YycG/YycF two-component system of Staphylococcus aureus. J Bacteriol. 186, 1175-1181 (2004).
    • (2004) J Bacteriol , vol.186 , pp. 1175-1181
    • Dubrac, S.1    Msadek, T.2
  • 43
    • 12444304518 scopus 로고    scopus 로고
    • Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: Design, conformation and conversion to ketoamide inhibitors
    • Bruton G, Huxley A, O'Hanlon PJ et al.: Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to ketoamide inhibitors. Eur. J Med. Chem. 38, 351-356 (2003).
    • (2003) Eur. J Med. Chem , vol.38 , pp. 351-356
    • Bruton, G.1    Huxley, A.2    O'Hanlon, P.J.3
  • 44
    • 0036783668 scopus 로고    scopus 로고
    • Discovery of a novel and potent class of Fabl-directed antibacterial agents
    • Payne DJ, Miller WH, Berry V et al.: Discovery of a novel and potent class of Fabl-directed antibacterial agents. Antimicrob. Agents Chemother. 46, 3118-3124 (2002).
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 3118-3124
    • Payne, D.J.1    Miller, W.H.2    Berry, V.3
  • 45
    • 33744994317 scopus 로고    scopus 로고
    • Platensimycin is a selective FabF inhibitor with potent antibiotic properties
    • Wang J, Soisson SM, Young K et al.: Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature 441, 358-361 (2006).
    • (2006) Nature , vol.441 , pp. 358-361
    • Wang, J.1    Soisson, S.M.2    Young, K.3
  • 46
    • 34250649348 scopus 로고    scopus 로고
    • Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
    • Wang J, Kodali S, Lee SH et al.: Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties. Proc. Natl Acad. Sci. USA 104, 7612-7616 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 7612-7616
    • Wang, J.1    Kodali, S.2    Lee, S.H.3
  • 47
    • 26844550453 scopus 로고    scopus 로고
    • Identification of inhibitors of bacterial enoyl-acyl carrier protein reductase
    • Moir DT: Identification of inhibitors of bacterial enoyl-acyl carrier protein reductase. Curr. Drug Targets Infect. Disord. 5, 297-305 (2005).
    • (2005) Curr. Drug Targets Infect. Disord , vol.5 , pp. 297-305
    • Moir, D.T.1
  • 48
    • 0032582528 scopus 로고    scopus 로고
    • Anchor structure of staphylococcal surface proteins. III. Role of the FemA, FemB, and FemX factors in anchoring surface proteins to the bacterial cell wall
    • Ton-That H, Labischinski H, Berger-Bachi B, Schneewind O: Anchor structure of staphylococcal surface proteins. III. Role of the FemA, FemB, and FemX factors in anchoring surface proteins to the bacterial cell wall. J. Biol. Chem. 273, 29143-29149 (1998).
    • (1998) J. Biol. Chem , vol.273 , pp. 29143-29149
    • Ton-That, H.1    Labischinski, H.2    Berger-Bachi, B.3    Schneewind, O.4
  • 49
    • 33947132188 scopus 로고    scopus 로고
    • Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis
    • Lovering AL, de Castro LH, Lim D, Strynadka NC: Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis. Science 315, 1402-1405 (2007).
    • (2007) Science , vol.315 , pp. 1402-1405
    • Lovering, A.L.1    de Castro, L.H.2    Lim, D.3    Strynadka, N.C.4
  • 50
    • 0034935859 scopus 로고    scopus 로고
    • Crystallization and preliminary x-ray analysis of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus
    • Harris MS, Herberg JT, Cialdella JI et al.: Crystallization and preliminary x-ray analysis of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus. Acta Crystallogr. D. Biol. Crystallogr. 57, 1032-1035 (2001).
    • (2001) Acta Crystallogr. D. Biol. Crystallogr , vol.57 , pp. 1032-1035
    • Harris, M.S.1    Herberg, J.T.2    Cialdella, J.I.3
  • 51
    • 0142126675 scopus 로고    scopus 로고
    • Bacterial wall as target for attack: Past, present, and future research
    • Koch AL: Bacterial wall as target for attack: past, present, and future research. Clin. Microbiol. Rev. 16, 673-687 (2003).
    • (2003) Clin. Microbiol. Rev , vol.16 , pp. 673-687
    • Koch, A.L.1
  • 53
    • 9144253860 scopus 로고    scopus 로고
    • New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity
    • Beyer D, Kroll HP, Endermann R et al.: New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity. Antimicrob. Agents Chemother. 2004, 48, 525-532 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.2004 , Issue.48 , pp. 525-532
    • Beyer, D.1    Kroll, H.P.2    Endermann, R.3
  • 54
    • 28844499031 scopus 로고    scopus 로고
    • Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents
    • Hurdle JG, O'Neill AJ, Chopra I: Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents. Antimicrob. Agents Chemother. 49, 4821-4833 (2005).
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 4821-4833
    • Hurdle, J.G.1    O'Neill, A.J.2    Chopra, I.3
  • 55
    • 34248339238 scopus 로고    scopus 로고
    • Aminoacyl-tRNA synthetases: Essential and still promising targets for new anti-infective agents
    • Ochsner UA, Sun X, Jarvis T. Critchley I, Janjic N: Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents. Expert Opin. Investig. Drugs 16, 573-593 (2007).
    • (2007) Expert Opin. Investig. Drugs , vol.16 , pp. 573-593
    • Ochsner, U.A.1    Sun, X.2    Jarvis, T.3    Critchley, I.4    Janjic, N.5
  • 56
    • 0032705343 scopus 로고    scopus 로고
    • Emergence of resistance during mupirocin treatment: Is it a problem in clinical practice?
    • Henkel T, Finlay J: Emergence of resistance during mupirocin treatment: is it a problem in clinical practice? J. Chemother. 11, 331-337 (1999).
    • (1999) J. Chemother , vol.11 , pp. 331-337
    • Henkel, T.1    Finlay, J.2
  • 57
    • 33846582343 scopus 로고    scopus 로고
    • Dual targeting of GyrB and ParE by a novel aminobenzimidazole class of antibacterial compounds
    • Grossman TH, Barrels DJ, Mullin S et al.: Dual targeting of GyrB and ParE by a novel aminobenzimidazole class of antibacterial compounds. Antimicrob. Agents Chemother. 51, 657-666 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 657-666
    • Grossman, T.H.1    Barrels, D.J.2    Mullin, S.3
  • 58
    • 33645791657 scopus 로고    scopus 로고
    • In vitro characterization of the antibacterial spectrum of novel bacterial type II topoisomerase inhibitors of the aminobenzimidazole class
    • Mani N, Gross CH, Parsons JD et al.: In vitro characterization of the antibacterial spectrum of novel bacterial type II topoisomerase inhibitors of the aminobenzimidazole class. Antimicrob. Agents Chemother. 50, 1228-1237 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 1228-1237
    • Mani, N.1    Gross, C.H.2    Parsons, J.D.3
  • 59
    • 33748569129 scopus 로고    scopus 로고
    • Staphylococcal vaccines and immunotherapy: To dream the impossible dream?
    • Projan SJ, Nesin M, Dunman PM: Staphylococcal vaccines and immunotherapy: to dream the impossible dream? Curr. Opin. Pharmacol 6, 473-479 (2006).
    • (2006) Curr. Opin. Pharmacol , vol.6 , pp. 473-479
    • Projan, S.J.1    Nesin, M.2    Dunman, P.M.3
  • 60
    • 4644255644 scopus 로고    scopus 로고
    • Staphylococci in colonization and disease: Prospective targets for drugs and vaccines
    • Götz F: Staphylococci in colonization and disease: prospective targets for drugs and vaccines. Curr. Opin. Microbiol. 7, 477-487 (2004).
    • (2004) Curr. Opin. Microbiol , vol.7 , pp. 477-487
    • Götz, F.1
  • 61
    • 0032436996 scopus 로고    scopus 로고
    • Surface protein adhesins of Staphylococcus aureus
    • Foster TJ, Höök M: Surface protein adhesins of Staphylococcus aureus. Trends Microbiol. 6, 484-488 (1998).
    • (1998) Trends Microbiol , vol.6 , pp. 484-488
    • Foster, T.J.1    Höök, M.2
  • 63
    • 31944433099 scopus 로고    scopus 로고
    • Human immunoglobulin G recognizing fibrinogen-binding surface proteins is protective against both Staphyloccus aureus and Staphyloccus epidermidis infections in vivo
    • Vernachio, JH, Bayer AS, Ames B et al.: Human immunoglobulin G recognizing fibrinogen-binding surface proteins is protective against both Staphyloccus aureus and Staphyloccus epidermidis infections in vivo. Antimicrob. Agents Chemother. 50, 511-518 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 511-518
    • Vernachio, J.H.1    Bayer, A.S.2    Ames, B.3
  • 64
    • 33745288996 scopus 로고    scopus 로고
    • Bloom BT INH-A21: a donor-selected staphylococcal human immune globulin for the prevention of law-onset neonatal staphylococcal infection. Expert Opin. Investig. Drugs 15, 703-707 (2006).
    • Bloom BT INH-A21: a donor-selected staphylococcal human immune globulin for the prevention of law-onset neonatal staphylococcal infection. Expert Opin. Investig. Drugs 15, 703-707 (2006).
  • 66
    • 0842346288 scopus 로고    scopus 로고
    • Development of StaphVAX®, a polysaccharide conjugate vaccine against S. aureus infection: From die lab bench to Phase III clinical trials
    • Fattom AI, Horwith G, Fuller S, Propst M, Naso R. Development of StaphVAX®, a polysaccharide conjugate vaccine against S. aureus infection: from die lab bench to Phase III clinical trials. Vaccine 22, 880-887 (2004).
    • (2004) Vaccine , vol.22 , pp. 880-887
    • Fattom, A.I.1    Horwith, G.2    Fuller, S.3    Propst, M.4    Naso, R.5
  • 67
    • 33947245064 scopus 로고    scopus 로고
    • Identification of the capsular polysaccharides in Staphylococcus aureus clinical isolates by PCR and agglutination tests
    • Verdier I, Durand G, Bes M et al.: Identification of the capsular polysaccharides in Staphylococcus aureus clinical isolates by PCR and agglutination tests. J. Clin. Microbiol. 45, 725-729 (2007).
    • (2007) J. Clin. Microbiol , vol.45 , pp. 725-729
    • Verdier, I.1    Durand, G.2    Bes, M.3
  • 68
    • 34347323824 scopus 로고    scopus 로고
    • Distribution of capsular and surface polysaccharide serotypes of Staphylococcus aureus
    • von Eiff C, Taylor KL, Mellmann A et al.: Distribution of capsular and surface polysaccharide serotypes of Staphylococcus aureus. Diagn. Microbiol. Infect. Dis. 58, 297-302 (2007).
    • (2007) Diagn. Microbiol. Infect. Dis , vol.58 , pp. 297-302
    • von Eiff, C.1    Taylor, K.L.2    Mellmann, A.3
  • 69
    • 33746907491 scopus 로고    scopus 로고
    • Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia
    • Weems JJ Jr, Steinberg JP, Filler S et al.: Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia. Antimicrob. Agents Chemother. 50, 2751-2755 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 2751-2755
    • Weems Jr, J.J.1    Steinberg, J.P.2    Filler, S.3
  • 70
  • 71
    • 9644259128 scopus 로고    scopus 로고
    • A humanized monoclonal antibody targeting Staphylococcus aureus
    • Patti JM: A humanized monoclonal antibody targeting Staphylococcus aureus. Vaccine 22(Suppl. 1), S39-S43 (2004).
    • (2004) Vaccine , vol.22 , Issue.SUPPL. 1
    • Patti, J.M.1
  • 72
    • 0034032774 scopus 로고    scopus 로고
    • Identification of an immunodominant ABC transporter in methicillin-resistant Staphylococcus aureus infections
    • Burnie JP Matthews RC, Carter T et al.: Identification of an immunodominant ABC transporter in methicillin-resistant Staphylococcus aureus infections. Infect. Immun. 68, 3200-3209 (2000).
    • (2000) Infect. Immun , vol.68 , pp. 3200-3209
    • Burnie, J.P.1    Matthews, R.C.2    Carter, T.3
  • 73
    • 33845700940 scopus 로고    scopus 로고
    • Anti-infective antibodies: Finding the path forward
    • Baker M: Anti-infective antibodies: finding the path forward. Nat. Biotechnol. 24, 1491-1493 (2006).
    • (2006) Nat. Biotechnol , vol.24 , pp. 1491-1493
    • Baker, M.1
  • 74
    • 33646848449 scopus 로고    scopus 로고
    • An immunogenicity study of a newly fusion protein Cna-FnBP vaccinated against Staphylococcus aureus infections in a mice model
    • Zhou H, Xiong ZY, Li HP, Zheng YL, Jiang YQ. An immunogenicity study of a newly fusion protein Cna-FnBP vaccinated against Staphylococcus aureus infections in a mice model. Vaccine 24, 4830-4837 (2006).
    • (2006) Vaccine , vol.24 , pp. 4830-4837
    • Zhou, H.1    Xiong, Z.Y.2    Li, H.P.3    Zheng, Y.L.4    Jiang, Y.Q.5
  • 75
    • 33645532283 scopus 로고    scopus 로고
    • Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model
    • Schaffer AC, Solinga RM, Cocchiaro J et al.: Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model. Infect. Immun. 74, 2145-2153 (2006).
    • (2006) Infect. Immun , vol.74 , pp. 2145-2153
    • Schaffer, A.C.1    Solinga, R.M.2    Cocchiaro, J.3
  • 76
    • 33645512072 scopus 로고    scopus 로고
    • A novel Staphylococcus aureus vaccine: Iron surface determinant B induces rapid antibody responses in rhesus; macaques and specific increased survival in a murine S. aureus sepsis model
    • Kuklin NA, Clark DJ, Secore S et al.: A novel Staphylococcus aureus vaccine: iron surface determinant B induces rapid antibody responses in rhesus; macaques and specific increased survival in a murine S. aureus sepsis model. Infect. Immun. 74, 2215-2223 (2006).
    • (2006) Infect. Immun , vol.74 , pp. 2215-2223
    • Kuklin, N.A.1    Clark, D.J.2    Secore, S.3
  • 77
    • 33845194899 scopus 로고    scopus 로고
    • Protective immune responses to a multi-gene DNA vaccine against Staphylococcus aureus
    • Gaudreau MC, Lacasse P, Talbot BG: Protective immune responses to a multi-gene DNA vaccine against Staphylococcus aureus. Vaccine 25, 814-824 (2007).
    • (2007) Vaccine , vol.25 , pp. 814-824
    • Gaudreau, M.C.1    Lacasse, P.2    Talbot, B.G.3
  • 78
    • 33750933334 scopus 로고    scopus 로고
    • Vaccine assembly from surface proteins of Staphylococcus aureus
    • Stranger-Jones YK, Bae T, Schneewind O: Vaccine assembly from surface proteins of Staphylococcus aureus. Proc. Natl Acad. Sci. USA 103, 16942-16947 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.103 , pp. 16942-16947
    • Stranger-Jones, Y.K.1    Bae, T.2    Schneewind, O.3
  • 79
    • 25444525134 scopus 로고    scopus 로고
    • Comparative opsonic and protective activities of Staphylacoccus aureus conjugate vaccines containing native or deacetylated staphylococcal poly-N-acetyl-β-(1-6)-glucosamine
    • Maira-Litran T, Kropec A, Goldmann DA, Pier GB: Comparative opsonic and protective activities of Staphylacoccus aureus conjugate vaccines containing native or deacetylated staphylococcal poly-N-acetyl-β-(1-6)-glucosamine. Infect. Immun. 73, 6752-6762 (2005).
    • (2005) Infect. Immun , vol.73 , pp. 6752-6762
    • Maira-Litran, T.1    Kropec, A.2    Goldmann, D.A.3    Pier, G.B.4
  • 80
    • 23744475984 scopus 로고    scopus 로고
    • Staphylacoccus aureus interactions with the endothelium: The role of bacterial 'secretable expanded repertoire adhesive molecules' (SERAM) in disturbing host defense systems
    • Chavakis T, Wiechmann K, Preissner KF Herrmann M: Staphylacoccus aureus interactions with the endothelium: the role of bacterial 'secretable expanded repertoire adhesive molecules' (SERAM) in disturbing host defense systems. Thromb. Haemost. 94, 278-285 (2005).
    • (2005) Thromb. Haemost , vol.94 , pp. 278-285
    • Chavakis, T.1    Wiechmann, K.2    Preissner, K.F.3    Herrmann, M.4
  • 82
    • 0242291985 scopus 로고    scopus 로고
    • Why is big Pharma getting out of antibacterial drug discovery?
    • Projan SJ: Why is big Pharma getting out of antibacterial drug discovery? Curr. Opin. Microbiol. 6, 427-430 (2003).
    • (2003) Curr. Opin. Microbiol , vol.6 , pp. 427-430
    • Projan, S.J.1
  • 83
    • 12944302098 scopus 로고    scopus 로고
    • Lack of development of new antimicrobial drugs: A potential serious threat to public health
    • Norrby SR, Nord CE, Finch R: Lack of development of new antimicrobial drugs: a potential serious threat to public health. Lancet Infect. Dis. 5, 115-119 (2005).
    • (2005) Lancet Infect. Dis , vol.5 , pp. 115-119
    • Norrby, S.R.1    Nord, C.E.2    Finch, R.3
  • 84
    • 0029759502 scopus 로고    scopus 로고
    • Staphylococcal peptidoglycan interpeptide bridge biosynthesis: A novel antistaphylococcal target?
    • Kopp U, Roos M, Wecke J, Labischinski H: Staphylococcal peptidoglycan interpeptide bridge biosynthesis: a novel antistaphylococcal target? Microb. Drug Resist. 2, 29-41 (1996).
    • (1996) Microb. Drug Resist , vol.2 , pp. 29-41
    • Kopp, U.1    Roos, M.2    Wecke, J.3    Labischinski, H.4
  • 85
    • 33750045457 scopus 로고    scopus 로고
    • Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies
    • Liu S, Chang JS, Herberg JT et al.: Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies. Proc. Natl Acad. Sci. USA 103, 15178-15183 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 15178-15183
    • Liu, S.1    Chang, J.S.2    Herberg, J.T.3
  • 86
    • 34147168547 scopus 로고    scopus 로고
    • Conditional mutation ofan essential putative glycoprotease eliminates autolysis in Staphylococcus aureus
    • Zheng L, Yu C, Bayles K, Lasa I, Ji Y: Conditional mutation ofan essential putative glycoprotease eliminates autolysis in Staphylococcus aureus. J. Bacteriol. 189, 2734-2742 (2007).
    • (2007) J. Bacteriol , vol.189 , pp. 2734-2742
    • Zheng, L.1    Yu, C.2    Bayles, K.3    Lasa, I.4    Ji, Y.5
  • 87
    • 27144460621 scopus 로고    scopus 로고
    • Dysregulation of bacterial proteolytic machinery by a new class of antibiotics
    • Brötz-Oesterhelt H, Beyer D, Kroll HP et al.: Dysregulation of bacterial proteolytic machinery by a new class of antibiotics. Nat. Med. 11, 1082-1087 (2005).
    • (2005) Nat. Med , vol.11 , pp. 1082-1087
    • Brötz-Oesterhelt, H.1    Beyer, D.2    Kroll, H.P.3
  • 89
    • 0030863413 scopus 로고    scopus 로고
    • Protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide in a modified model of endocarditis in rats
    • Lee JC, Park JS, Shepherd SE, Carey V Fattom A: Protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide in a modified model of endocarditis in rats. Infect. Immun. 65, 4146-4151 (1997).
    • (1997) Infect. Immun , vol.65 , pp. 4146-4151
    • Lee, J.C.1    Park, J.S.2    Shepherd, S.E.3    Carey, V.4    Fattom, A.5
  • 90
    • 1642475071 scopus 로고    scopus 로고
    • Staphylococcus aureus capsular polysaccharides
    • O'Riordan K, Lee JC: Staphylococcus aureus capsular polysaccharides. Clin. Microbiol. Rev. 17, 218-234 (2004).
    • (2004) Clin. Microbiol. Rev , vol.17 , pp. 218-234
    • O'Riordan, K.1    Lee, J.C.2
  • 91
    • 33645767174 scopus 로고    scopus 로고
    • Identification of in vivo-expressed antigens of Staphylococcus aureus and their use in vaccinations for protection against nasal carriage
    • Clarke SR, Brummell KJ, Horsburgh MJ et al.: Identification of in vivo-expressed antigens of Staphylococcus aureus and their use in vaccinations for protection against nasal carriage. J. Infect. Dis. 193, 1098-1108 (2006).
    • (2006) J. Infect. Dis , vol.193 , pp. 1098-1108
    • Clarke, S.R.1    Brummell, K.J.2    Horsburgh, M.J.3
  • 92
    • 33646358696 scopus 로고    scopus 로고
    • Characterization of the opsonic and protective activity against Staphylococcus aureus of fully human monoclonal antibodies specific for the bacterial surface polysaccharide poly-N-acetylglucosamine
    • Kelly-Quintos C, Cavacini LA, Posner MR, Goldmann D, Pier GB: Characterization of the opsonic and protective activity against Staphylococcus aureus of fully human monoclonal antibodies specific for the bacterial surface polysaccharide poly-N-acetylglucosamine. Infect. Immun. 74, 2742-2750 (2006).
    • (2006) Infect. Immun , vol.74 , pp. 2742-2750
    • Kelly-Quintos, C.1    Cavacini, L.A.2    Posner, M.R.3    Goldmann, D.4    Pier, G.B.5
  • 93
    • 0035858128 scopus 로고    scopus 로고
    • Antibodies against a truncated Staphylococcus aureus fibronectin-binding protein protect against dissemination of infection in the rat
    • Rennermalm A, Li YH, Bohaufs L et al.: Antibodies against a truncated Staphylococcus aureus fibronectin-binding protein protect against dissemination of infection in the rat. Vaccine 19, 3376-3383 (2001).
    • (2001) Vaccine , vol.19 , pp. 3376-3383
    • Rennermalm, A.1    Li, Y.H.2    Bohaufs, L.3
  • 94
    • 7444231707 scopus 로고    scopus 로고
    • Immune responses to a DNA/ protein vaccination strategy against Staphylococcus aureus induced mastitis in dairy cows
    • Shkreta L, Talbot BG, Diarra MS, Lacasse P: Immune responses to a DNA/ protein vaccination strategy against Staphylococcus aureus induced mastitis in dairy cows. Vaccine 23, 114-126 (2004).
    • (2004) Vaccine , vol.23 , pp. 114-126
    • Shkreta, L.1    Talbot, B.G.2    Diarra, M.S.3    Lacasse, P.4
  • 95
    • 0037945207 scopus 로고    scopus 로고
    • The role of fibronectin binding proteins in the pathogenesis of Staphylococcus aureus infections
    • Menzies BE: The role of fibronectin binding proteins in the pathogenesis of Staphylococcus aureus infections. Curr. Opin Infect. Dis. 16, 225-229 (2003).
    • (2003) Curr. Opin Infect. Dis , vol.16 , pp. 225-229
    • Menzies, B.E.1
  • 96
    • 0242475185 scopus 로고    scopus 로고
    • Understanding the mechanism of action of the exfoliative toxins of Staphylococcus aureus
    • Ladhani S: Understanding the mechanism of action of the exfoliative toxins of Staphylococcus aureus. FEMS Immunol. Med. Microbiol. 39, 181-189 (2003).
    • (2003) FEMS Immunol. Med. Microbiol , vol.39 , pp. 181-189
    • Ladhani, S.1
  • 98
    • 27944495724 scopus 로고    scopus 로고
    • Virulence determinants in Staphylococcus aureus and their involvement in clinical syndromes
    • Ferry T, Perpoint T, Vandenesch F, Etienne J: Virulence determinants in Staphylococcus aureus and their involvement in clinical syndromes. Curr. Infect. Dis. Rep. 7, 420-428 (2005).
    • (2005) Curr. Infect. Dis. Rep , vol.7 , pp. 420-428
    • Ferry, T.1    Perpoint, T.2    Vandenesch, F.3    Etienne, J.4
  • 99
    • 0033053177 scopus 로고    scopus 로고
    • α-toxin and γ-toxin jointly promote Staphylococcus aureus virulence in routine septic arthritis
    • Nilsson IM, Hartford O, Foster T, Tarkowski A: α-toxin and γ-toxin jointly promote Staphylococcus aureus virulence in routine septic arthritis. Infect. Immun. 67, 1045-1049 (1999).
    • (1999) Infect. Immun , vol.67 , pp. 1045-1049
    • Nilsson, I.M.1    Hartford, O.2    Foster, T.3    Tarkowski, A.4
  • 100
    • 0037006653 scopus 로고    scopus 로고
    • Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients
    • Gillet Y, Issartel B, Vanhems P et al.: Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet 359, 753-759 (2002).
    • (2002) Lancet , vol.359 , pp. 753-759
    • Gillet, Y.1    Issartel, B.2    Vanhems, P.3
  • 101
    • 0028824813 scopus 로고
    • The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure
    • De Kimpe SJ, Kengatharan M, Thiemermann C, Vane JR: The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure. Proc. Natl Acad. Sci. USA 92, 10359-10363 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 10359-10363
    • De Kimpe, S.J.1    Kengatharan, M.2    Thiemermann, C.3    Vane, J.R.4
  • 102
    • 0033829979 scopus 로고    scopus 로고
    • Human antibody response during sepsis against targets expressed by methicillin resistant Staphylococcus aureus
    • Lorenz U, Ohlsen K, Karch H, Hecker M, Thiede A, Hacker J: Human antibody response during sepsis against targets expressed by methicillin resistant Staphylococcus aureus. FEMS Immunol. Med. Microbiol. 29, 145-153 (2000).
    • (2000) FEMS Immunol. Med. Microbiol , vol.29 , pp. 145-153
    • Lorenz, U.1    Ohlsen, K.2    Karch, H.3    Hecker, M.4    Thiede, A.5    Hacker, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.