Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients

Lancet

Volumn 359, Issue 9308, 2002, Pages 753-759

  Gillet, Yves ^a   Issartel, Bertrand ^b   Vanhems, Philippe ^a   Fournet, Jean Christophe ^c   Lina, Gerard ^b   Bes, Michèle ^b   Vandenesch, François ^b   Piémont, Yves ^d   Brousse, Nicole ^c   Floret, Daniel ^a   Etienne, Jerome ^b  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b UNIVERSITÉ LYON 1   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; LEUKOCIDIN; PANTON VALENTINE LEUKOCIDIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL PNEUMONIA; BODY TEMPERATURE; BRONCHUS MUCOSA; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; FOLLOW UP; HEART RATE; HEMOPTYSIS; HISTOPATHOLOGY; HOSPITALIZATION; HUMAN; IMMUNOCOMPETENCE; INFECTION RISK; LENGTH OF STAY; LEUKOPENIA; LUNG ALVEOLUS WALL; PLEURA EFFUSION; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; SURVIVAL RATE; THORAX RADIOGRAPHY; TRACHEA MUCOSA;

EID: 0037006653     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(02)07877-7     Document Type: Article

References (35)

1. Respiratory tract infections
2. Nosocomial infections in combined medical-surgical intensive care units in the United States
3. The clinical spectrum of Staphylococcus aureus pulmonary infection
4. Bacteremic Staphylococcus aureus pneumonia
5. The current spectrum of Staphylococcus aureus infection in a tertiary care hospital
6. Epidemiological data on Staphylococcus aureus strains producing synergohymenotropic toxins
7. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia
8. Involvement of enterotoxins G and I in staphylococcal toxic shock syndrome and staphylococcal scarlet fever
9. Identification of methicillin-resistant strains of staphylococci by polymerase chain reaction
10. Rapid method for epidemiological evaluation of gram-positive cocci by field inversion gel electrophoresis
11. Validation of a pneumonia prognostic index using the MedisGroups comparative hospital database
12. Sequencing of leucocidin R from Staphylococcus aureus P83 suggests that staphylococcal leucocidins and gamma-hemolysin are members of a single, two-component family of toxin
13. Characterization of a novel structural member, LukE-LukD, of the bi-component staphylococcal leucotoxins family
14. Panton-Valentine leucocidin and gamma-hemolysin from Staphylococcus aureus ATCC 49775 are encoded by distinct genetic loci and have different biological activities
15. Prophage, phiPV83-pro, carrying Panton-Valentine leukocidin genes, on the Staphylococcus aureus P83 chromosome: Comparative analysis of the genome structures of phiPV83-pro, phiPVL, phi11, and other phages
16. Complete nucleotide sequence and molecular characterization of the temperate staphylococcal bacteriophage phiPVL carrying Panton-Valentine leukocidin genes
17. Phage conversion of Panton-Valentine leukocidin in Staphylococcus aureus: Molecular analysis of a PVL-converting phage, phiSLT
18. The staphylococcal pore-forming leukotoxins open Ca2+ channels in the membrane of human polymorphonuclear neutrophils
19. Crystal structure of the F component of the Panton-Valentine leucocidin
20. Flow cytometric determination of Panton-Valentine leucocidin S component binding
21. The interaction of Staphylococcus aureus bi-component gamma-hemolysins and leucocidins with cells and lipid membranes
22. Effect of Staphylococcus aureus leucocidins inflammatory mediator release from human granulocytes
23. Identification of staphylococcal Panton-Valentine leukocidin as a potent dermonecrotic toxin
24. Adherence of type I Streptococcus pneumoniae to tracheal epithelium of mice infected with influenza A/PR8 virus
25. Bacterial pneumonia during the Hong-Kong influenza epidemic of 1968-1969: Experienced in a city-county hospital
26. Cell wall-associated protein A as a tool for immunolocalization of Staphylococcus aureus in infected human airway epithelium
27. Pore formation by two-component leukocidin from Staphylococcus aureus within the membrane of human polymorphonuclear leukocytes
28. Coagulase-positive staphylococcal infections
29. Bacterial infections
30. Pathological case of the month. Fatal hemorrhagic staphylococcal pneumonia
31. Severe community acquired pneumonia due to Staphylococcus aureus
32. Metastatic staphylococcal lung abscess due to a cutaneous furuncle
33. Breast milk transmission of a Panton-Valentine leukocidin-producing Staphylococcus aureus strain causing infantile pneumonia
34. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus - Minnesota and North Dakota, 1997-1999
35. Staphylococcus aureus pneumonia