Antibodies against a truncated Staphylococcus aureus fibronectin-binding protein protect against dissemination of infection in the rat

Vaccine

Volumn 19, Issue 25-26, 2001, Pages 3376-3383

  Rennermalm, Anna ^a   Li, Ying Hua ^b   Bohaufs, Linda ^a   Jarstrand, Connie ^a   Brauner, Annelie ^b   Brennan, Frank R ^c   Flock, Jan Ingmar ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c Axis Genetics plc   (United Kingdom)

Author keywords

Arthritis endocarditis model; Chimeric plant viruses; Fibronectin binding protein; S. aureus

Indexed keywords

BACTERIUM ANTIBODY; BINDING PROTEIN; FIBRONECTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEREMIA; BACTERIAL ARTHRITIS; BACTERIAL ENDOCARDITIS; CONTROLLED STUDY; FEMALE; IMMUNIZATION; INFECTION PREVENTION; MACROPHAGE; MOSAIC VIRUS; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; STAPHYLOCOCCUS AUREUS; VIRUS CARRIER; WEIGHT REDUCTION;

ADHESINS, BACTERIAL; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY SPECIFICITY; BACTEREMIA; BACTERIAL PROTEINS; BACTERIAL VACCINES; CARRIER PROTEINS; CHIMERA; COMOVIRUS; ENDOCARDITIS, BACTERIAL; FEMALE; MOLECULAR SEQUENCE DATA; OPSONIN PROTEINS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; VACCINES, SYNTHETIC;

EID: 0035858128     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(01)00080-9     Document Type: Article

References (29)

1. Clinical and molecular aspects of the pathogenesis of Staphylococcus aureus bone and joint infections
2. Consequences of intravascular catheter sepsis
3. Prospective study of 114 consecutive episodes of Staphylococcus aureus bacteraemia
4. Optimal duration of therapy for catheter-related Staphylococcus aureus bacteraemia: A study of 55 cases and review
5. Staphylococcus aureus
6. Experimental endocarditis in the rat secondary to septic arthritisinduced by Staphylococcus aureus
7. Immunization with fibronectin binding protein from Staphylococcus aureus protects against experimental endocarditis in rats
8. Collagen binding of Staphylococcus aureus is a virulence factor in experimental endocarditis
9. Protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide in a modified model of endocarditis in rats
10. Two different genes encode fibronectin binding proteins in Staphylococcus aureus. The complete nucleotide sequence and characterization of the second gene
11. Nucleotide sequence of the gene for a fibronectin-binding protein from Staphylococcus aureus: Use of this peptide sequence in the synthesis of biologically active peptides
12. Vaccination against Staphylococcus aureus mastitis: Immunological response of mice vaccinated with fibronectin-binding protein (FnBP-A) to challenge with S. aureus
13. Reconsideration of the role of fibronectin binding in endocarditis caused by Staphylococcus aureus
14. Opsonization of Staphylococcus aureus with a fibronectin-binding protein antiserum induces protection in mice
15. Protective opsonic activity of antibodies against fibronectin-binding proteins (FnBPs) of Staphylococcus aureus
16. Interaction of N-terminal fragments of fibronectin with synthetic and recombinant D motifs from its binding protein on Staphylococcus aureus studied using fluorescence anisotropy
17. Fibronectin binding determinants of the Staphylococcus aureus fibronectin receptor
18. A chimaeric plant virus vaccine protects mice against a bacterial infection
19. Plant-derived vaccine protects target animals against a viral disease
20. Immunogenicity of peptides derived from a fibronectin-binding protein of S. aureus expressed on two different plant viruses
21. Chimeric plant virus particles administered nasally or orally induce systemic and mucosal immune responses in mice
22. The Staphylococcus aureus collagen adhesin is a virulence determinant in experimental septic arthritis
23. Structure/function studies on QS-21, a unique immunological adjuvant from Quillaja saponaria
24. The influence of opsonization with specific antibody and complement on the nitroblue tetrazolium (NBT) reduction of neutrophil granulocytes: A methodological study and a clinical application
25. Effect of surfactant on nitroblue tetrazolium reduction of polymorphonuclear leucocytes stimulated with type Ia group B streptococci
26. Antibody response to fibronectin-binding adhesin FnbpA in patients with Staphylococcus aureus infections
27. A monoclonal antibody enhances ligand binding of fibronectin MSCRAMM (adhesin) from Streptococcus dysgalactiae
28. Detection in rabbit sera of blocking antibodies against staphylococcal fibronectin-binding protein by enzyme-linked immunosorbent assay
29. Immunological response to a Staphylococcus aureus fibronectin-binding protein