메뉴 건너뛰기




Volumn 181, Issue 21, 1999, Pages 6585-6590

Regulated antisense RNA eliminates alpha-toxin virulence in Staphylococcus aureus infection

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOXIN; COMPLEMENTARY RNA;

EID: 0032728823     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.181.21.6585-6590.1999     Document Type: Article
Times cited : (124)

References (27)
  • 2
    • 0030862228 scopus 로고    scopus 로고
    • Hyperproduction of alpha-toxin by Staphylococcus aureus results in paradoxically reduced virulence in experimental endocarditis a host defense role for platelet microbicidal proteins
    • Bayerer, A. S., M. D. Ramos, B. E. Menzies, M. R. Yeaman, A. J. Shen, and A. L. Cheung. 1997. Hyperproduction of alpha-toxin by Staphylococcus aureus results in paradoxically reduced virulence in experimental endocarditis a host defense role for platelet microbicidal proteins. Infect. Immun. 65: 4652-4660.
    • (1997) Infect. Immun. , vol.65 , pp. 4652-4660
    • Bayerer, A.S.1    Ramos, M.D.2    Menzies, B.E.3    Yeaman, M.R.4    Shen, A.J.5    Cheung, A.L.6
  • 3
    • 0028821179 scopus 로고
    • Suppression of villin expression by antisense RNA impairs brush border assembly in polarized epithelial intestinal cells
    • Beauregard, M. C., E. Pringault, S. Robine, and D. Louvard. 1995. Suppression of villin expression by antisense RNA impairs brush border assembly in polarized epithelial intestinal cells. EMBO J. 14:409-421.
    • (1995) EMBO J. , vol.14 , pp. 409-421
    • Beauregard, M.C.1    Pringault, E.2    Robine, S.3    Louvard, D.4
  • 4
    • 0029078161 scopus 로고
    • Insertional inactivation of a chromosomal locus that modulates expression of potential virulence determinants in Staphylococcus aureus
    • Cheung, A. L., C. Wolz, M. R. Yeaman, and A. S. Bayer. 1995. Insertional inactivation of a chromosomal locus that modulates expression of potential virulence determinants in Staphylococcus aureus. J. Bacteriol. 177:3220-3226.
    • (1995) J. Bacteriol. , vol.177 , pp. 3220-3226
    • Cheung, A.L.1    Wolz, C.2    Yeaman, M.R.3    Bayer, A.S.4
  • 5
    • 0028358260 scopus 로고
    • Analysis and construction of stable phenotypes in gram-negative bacteria with Tn5- and Tn10-derived minitransposons
    • de Lorenzo, V., and R, N. Timms. 1994. Analysis and construction of stable phenotypes in gram-negative bacteria with Tn5- and Tn10-derived minitransposons. Methods Enzymol. 235:386-405.
    • (1994) Methods Enzymol. , vol.235 , pp. 386-405
    • De Lorenzo, V.1    Timms, R.N.2
  • 6
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., S. Xu, M. K. Montgomery, S. A. Kostas, S. E. Driver, and C. C. Mello. 1998. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-810.
    • (1998) Nature , vol.391 , pp. 806-810
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 7
    • 0025143351 scopus 로고
    • Regulated expression of heterologous genes in Bacillus subtilis using the Tn10 encoded tet regulatory elements
    • Geissendorfer, M., and W. Hillen. 1990. Regulated expression of heterologous genes in Bacillus subtilis using the Tn10 encoded tet regulatory elements. Appl. Microbiol. Biotechnol. 33:657-663.
    • (1990) Appl. Microbiol. Biotechnol. , vol.33 , pp. 657-663
    • Geissendorfer, M.1    Hillen, W.2
  • 8
    • 0031979354 scopus 로고    scopus 로고
    • Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA
    • Good, L., and P. E. Nielsen. 1998. Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA. Nat. Biotechnol. 16:355-358.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 355-358
    • Good, L.1    Nielsen, P.E.2
  • 9
    • 0021747672 scopus 로고
    • Primary sequence of the alpha-toxin gene from Staphylococcus aureus Wood 46
    • Gray, G. S., and M. Kehoe. 1984. Primary sequence of the alpha-toxin gene from Staphylococcus aureus Wood 46. Infect. Immun. 46:615-618.
    • (1984) Infect. Immun. , vol.46 , pp. 615-618
    • Gray, G.S.1    Kehoe, M.2
  • 10
    • 0029117137 scopus 로고
    • Simultaneous identification of bacterial virulence genes by negative selection
    • Hensel, M. J. E. Shea, C. Gleeson, M. D. Jones, E. Dalton, and D. W. Holden. 1995. Simultaneous identification of bacterial virulence genes by negative selection. Science 269:400-403.
    • (1995) Science , vol.269 , pp. 400-403
    • Hensel1    Shea, M.J.E.2    Gleeson, C.3    Jones, M.D.4    Dalton, E.5    Holden, D.W.6
  • 11
    • 0020315189 scopus 로고
    • Nucleotide sequence and functional map of pE194, a plasmid that specifics inducible resistance to macrolide, lincosamide and streptogramin type B antibiotics
    • Horinouchi, S., and B. Weisblum. 1982. Nucleotide sequence and functional map of pE194, a plasmid that specifics inducible resistance to macrolide, lincosamide and streptogramin type B antibiotics. J. Bacteriol. 150:804-814.
    • (1982) J. Bacteriol. , vol.150 , pp. 804-814
    • Horinouchi, S.1    Weisblum, B.2
  • 12
    • 0022883908 scopus 로고
    • Differential utilization of Staphylococus aureus promoter sequences by Escherichia coli and Bacillus subtilis
    • Hudson, M. C., and G. C. Stewart. 1986. Differential utilization of Staphylococus aureus promoter sequences by Escherichia coli and Bacillus subtilis. Gene 48:93-100.
    • (1986) Gene , vol.48 , pp. 93-100
    • Hudson, M.C.1    Stewart, G.C.2
  • 13
    • 9044220226 scopus 로고    scopus 로고
    • C5a peptidase alters clearance and trafficking of group A streptococci by infected mice
    • Ji, Y. L. Mclandsborough, A. Kondagunta, and P. P. Cleary. 1996. C5a peptidase alters clearance and trafficking of group A streptococci by infected mice. Infect. Immun. 64:503-510.
    • (1996) Infect. Immun. , vol.64 , pp. 503-510
    • Ji, Y.1    Mclandsborough, L.2    Kondagunta, A.3    Cleary, P.P.4
  • 14
    • 0031022928 scopus 로고    scopus 로고
    • Expression of an antisense hla fragment in Staphylococcus aureus reduces alpha-toxin production in vitro and attenuates lethal activity in murine model
    • Kernodle, D. S., R. K. R. Voladri, B. E. Menzies, C. C. Hager, and K. M. Edwards. 1997. Expression of an antisense hla fragment in Staphylococcus aureus reduces alpha-toxin production in vitro and attenuates lethal activity in murine model. Infect. Immun. 65:179-184.
    • (1997) Infect. Immun. , vol.65 , pp. 179-184
    • Kernodle, D.S.1    Voladri, R.K.R.2    Menzies, B.E.3    Hager, C.C.4    Edwards, K.M.5
  • 15
    • 0025651169 scopus 로고
    • High-frequency transformation of Staphylococcus aureus by electroporation
    • Kraemer, G. R., and J. J. Iacmdolo. 1990. High-frequency transformation of Staphylococcus aureus by electroporation. Curr. Microbiol. 21:373-376.
    • (1990) Curr. Microbiol. , vol.21 , pp. 373-376
    • Kraemer, G.R.1    Iacmdolo, J.J.2
  • 16
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 17
    • 0028216879 scopus 로고
    • Site-directed mutagenesis of the alpha-toxin gene of Staphylococcus aureus: Role of histidines in toxin activity in vitro and in a murine model
    • Menzies, B. E., and D. S. Kernodle. 1994. Site-directed mutagenesis of the alpha-toxin gene of Staphylococcus aureus: role of histidines in toxin activity in vitro and in a murine model. Infect. Immun. 62:1843-1847.
    • (1994) Infect. Immun. , vol.62 , pp. 1843-1847
    • Menzies, B.E.1    Kernodle, D.S.2
  • 18
    • 0002794633 scopus 로고
    • The staphylococcus as a molecular genetic system
    • R. P. Novick (ed.). VCH Publishers, New York, N.Y.
    • Novick, R. P. 1990. The staphylococcus as a molecular genetic system, p. 1-40. In R. P. Novick (ed.), Molecular biology of the staphylococci. VCH Publishers, New York, N.Y.
    • (1990) Molecular Biology of the Staphylococci , pp. 1-40
    • Novick, R.P.1
  • 19
    • 0026638376 scopus 로고
    • Constitutive synthesis of polyoma antisense RNA renders cells immune to virus infection
    • Ottavio, L., O. Sthandler, L. Ricci, C. Passananti, and P. Amati. 1992. Constitutive synthesis of polyoma antisense RNA renders cells immune to virus infection. Virology 189:812-816.
    • (1992) Virology , vol.189 , pp. 812-816
    • Ottavio, L.1    Sthandler, O.2    Ricci, L.3    Passananti, C.4    Amati, P.5
  • 20
    • 0016415604 scopus 로고
    • Chloramphenicol acetyltransferase from chloramphenicol resistant bacteria
    • Shaw, W. V. 1975. Chloramphenicol acetyltransferase from chloramphenicol resistant bacteria. Methods Enzymol. 43:737-755.
    • (1975) Methods Enzymol. , vol.43 , pp. 737-755
    • Shaw, W.V.1
  • 21
    • 0024390511 scopus 로고
    • Impaired clearance of aerosolized Legionella pneumophila in corticosteroid-treated rats: A model of legionnaires' disease in the compromised host
    • Skerrett, S. J., R. A. Schmidt, and T. R. Martin. 1989. Impaired clearance of aerosolized Legionella pneumophila in corticosteroid-treated rats: a model of legionnaires' disease in the compromised host. J. Infect. Dis. 160:261-273.
    • (1989) J. Infect. Dis. , vol.160 , pp. 261-273
    • Skerrett, S.J.1    Schmidt, R.A.2    Martin, T.R.3
  • 22
    • 0031823250 scopus 로고    scopus 로고
    • Degradation pathway of CopA, the antisense RNA that controls replication of plasmid R1
    • Soderbom, F., and E. G. H. Wagner. 1998. Degradation pathway of CopA, the antisense RNA that controls replication of plasmid R1. Microbiology 144:1907-1917.
    • (1998) Microbiology , vol.144 , pp. 1907-1917
    • Soderbom, F.1    Wagner, E.G.H.2
  • 23
    • 0033590613 scopus 로고    scopus 로고
    • Integrational plasmids for the tetracycline-regulated expression of genes in Streptococcus pneumoniae
    • Stieger, M., B. Wohlgensinger, M. Kamber, R. Lutz, and W. Keck. 1999. Integrational plasmids for the tetracycline-regulated expression of genes in Streptococcus pneumoniae. Gene 226:243-251.
    • (1999) Gene , vol.226 , pp. 243-251
    • Stieger, M.1    Wohlgensinger, B.2    Kamber, M.3    Lutz, R.4    Keck, W.5
  • 24
    • 0030872427 scopus 로고    scopus 로고
    • A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly
    • von Eiff, C., C. Heilmann, R. A. Proctor, C. Woltz, G. Petters, and F. Gotz. 1997. A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly. J. Bacteriol. 179:4706-4712.
    • (1997) J. Bacteriol. , vol.179 , pp. 4706-4712
    • Von Eiff, C.1    Heilmann, C.2    Proctor, R.A.3    Woltz, C.4    Petters, G.5    Gotz, F.6
  • 25
    • 85041131924 scopus 로고
    • Antisense RNA control in bacteria, phages, and plasmids
    • Wagner, E. G. H., and R. W. Simons. 1994. Antisense RNA control in bacteria, phages, and plasmids. Annu. Rev. Microbiol. 48:717-742.
    • (1994) Annu. Rev. Microbiol. , vol.48 , pp. 717-742
    • Wagner, E.G.H.1    Simons, R.W.2
  • 26
    • 0031733825 scopus 로고    scopus 로고
    • Antisense RNA to ahpC, an oxidative stress defence gene involved in isoniazid resistance indicates that AhpC of Mycobacterium bovis has virulence properties
    • Wilson, T., G. W. deLisle, J. A. Marcinkeviciene, J. S. Blanchard, and D. M. Collins. 1998. Antisense RNA to ahpC, an oxidative stress defence gene involved in isoniazid resistance indicates that AhpC of Mycobacterium bovis has virulence properties. Microbiology 144:2687-2695.
    • (1998) Microbiology , vol.144 , pp. 2687-2695
    • Wilson, T.1    DeLisle, G.W.2    Marcinkeviciene, J.A.3    Blanchard, J.S.4    Collins, D.M.5
  • 27
    • 0021943518 scopus 로고
    • Improved m13 phage cloning vectors and host strains: Nucleotide sequences of the m13mp18 and pUC19 vectors
    • Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved m13 phage cloning vectors and host strains: nucleotide sequences of the m13mp18 and pUC19 vectors. Gene 33:103-119.
    • (1985) Gene , vol.33 , pp. 103-119
    • Yanisch-Perron, C.1    Vieira, J.2    Messing, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.