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Volumn 14, Issue 5-6, 2003, Pages 385-390

Animal models of depression: Challenges from a drug development perspective

Author keywords

Animal models; Behavior; Depression; Drug development; Functional imaging

Indexed keywords

AMPA RECEPTOR AGONIST; ANTIDEPRESSANT AGENT; APREPITANT; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; GLUCOCORTICOID RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SUBSTANCE P ANTAGONIST; VASOPRESSIN RECEPTOR ANTAGONIST;

EID: 0141645449     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (54)

References (48)
  • 1
    • 0020060508 scopus 로고
    • The cholinolytic biperiden in depression: An acute placebo-controlled study
    • Beckman H, Moise H-W (1982). The cholinolytic biperiden in depression: an acute placebo-controlled study. Arch Gen Psychiat Nerven 231:213-220.
    • (1982) Arch Gen Psychiat Nerven , vol.231 , pp. 213-220
    • Beckman, H.1    Moise, H.-W.2
  • 4
    • 0033537751 scopus 로고    scopus 로고
    • Can the placebo be the cure?
    • Enserink M (1999). Can the placebo be the cure? Science 284:238-240.
    • (1999) Science , vol.284 , pp. 238-240
    • Enserink, M.1
  • 5
    • 0034544727 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, efficacy, safety, and pharmacokinetic study of INN 00835, a novel antidepressant peptide, in the treatment of major depression
    • Feighner JP, Ehrensing RH, Kastin AJ, Leonard BE, Sverdlov L, Nicolau G, et al. (2000). A double-blind, placebo-controlled, efficacy, safety, and pharmacokinetic study of INN 00835, a novel antidepressant peptide, in the treatment of major depression. J Affect Disord 61:119-126.
    • (2000) J Affect Disord , vol.61 , pp. 119-126
    • Feighner, J.P.1    Ehrensing, R.H.2    Kastin, A.J.3    Leonard, B.E.4    Sverdlov, L.5    Nicolau, G.6
  • 6
    • 0034764916 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of INN 00835 (nemifitide) in the treatment of outpatients with major depression
    • Feighner JP, Ehrensing RH, Kastin A J, Patel A, Sverdlov L, Hlavka J, et al. (2001). Double-blind, placebo-controlled study of INN 00835 (nemifitide) in the treatment of outpatients with major depression. Int Clin Psychopharmacol 16:345-352.
    • (2001) Int Clin Psychopharmacol , vol.16 , pp. 345-352
    • Feighner, J.P.1    Ehrensing, R.H.2    Kastin, A.J.3    Patel, A.4    Sverdlov, L.5    Hlavka, J.6
  • 8
    • 0029939345 scopus 로고    scopus 로고
    • Psychosocial stress in tree shrews: Clomipramine counteracts behavioral and endocrine changes
    • Fuchs E, Kramer M, Hermes B, Netter P, Hiemke C (1996). Psychosocial stress in tree shrews: clomipramine counteracts behavioral and endocrine changes. Pharmacol Biochem Behav 54:219-228.
    • (1996) Pharmacol Biochem Behav , vol.54 , pp. 219-228
    • Fuchs, E.1    Kramer, M.2    Hermes, B.3    Netter, P.4    Hiemke, C.5
  • 9
    • 0037197989 scopus 로고    scopus 로고
    • Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders
    • Griebel G, Simiand J, Serradeil-Le Gal C, Wagnon J, Pascal M, Scatton B, et al. (2002a). Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders. Proc Natt Acad Sci USA 99:6370-6375.
    • (2002) Proc Natt Acad Sci USA , vol.99 , pp. 6370-6375
    • Griebel, G.1    Simiand, J.2    Serradeil-Le Gal, C.3    Wagnon, J.4    Pascal, M.5    Scatton, B.6
  • 10
    • 18344394149 scopus 로고    scopus 로고
    • 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S) -2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine hydrochloride (SSR125543A), a potent and selective corticotrophin-releasing factor (1) receptor antagonist. II. Characterization in rodent models of stress-related disorders
    • Griebel G, Simiand J, Steinberg R, Jung M, Gully D, Roger P, et al. (2002b). 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S) -2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine hydrochloride (SSR125543A), a potent and selective corticotrophin-releasing factor (1) receptor antagonist. II. Characterization in rodent models of stress-related disorders. J Pharmacol Exp Ther 301:333-345.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 333-345
    • Griebel, G.1    Simiand, J.2    Steinberg, R.3    Jung, M.4    Gully, D.5    Roger, P.6
  • 11
    • 0015086189 scopus 로고
    • Production of depressive behaviors in young monkeys
    • Harlow HF, Suomi SJ (1971). Production of depressive behaviors in young monkeys. J Aut Child Schiz 1:246-255.
    • (1971) J Aut Child Schiz , vol.1 , pp. 246-255
    • Harlow, H.F.1    Suomi, S.J.2
  • 12
    • 0024842515 scopus 로고
    • Effects of ethanol on fight- or swim-stressed mice in Porsolt's swim test
    • Hilakivi LA, Durcan MJ, Lister RG (1989). Effects of ethanol on fight- or swim-stressed mice in Porsolt's swim test. Neuropsychopharmacology 2:293-298.
    • (1989) Neuropsychopharmacology , vol.2 , pp. 293-298
    • Hilakivi, L.A.1    Durcan, M.J.2    Lister, R.G.3
  • 14
    • 0013805530 scopus 로고
    • Selective block of rat mouse killing by antidepressants
    • Horovitz ZP (1965). Selective block of rat mouse killing by antidepressants. Life Sci 4:1909-1912.
    • (1965) Life Sci , vol.4 , pp. 1909-1912
    • Horovitz, Z.P.1
  • 15
    • 0021325246 scopus 로고
    • Use of psychostimulants in medically ill patients with neurological disease and major depression
    • Kaufmann MW, Cassem NH, Murray GB, Jenike M (1984). Use of psychostimulants in medically ill patients with neurological disease and major depression. Can J Psychiat 29:46-49.
    • (1984) Can J Psychiat , vol.29 , pp. 46-49
    • Kaufmann, M.W.1    Cassem, N.H.2    Murray, G.B.3    Jenike, M.4
  • 17
    • 0029890642 scopus 로고    scopus 로고
    • Antisense to the glucocorticoid receptor in hippocampal dentate gyrus reduces immobility in forced swim test
    • Korte SM, de Kloet ER, Buwalda B, Bouman SD, Bohus B (1996). Antisense to the glucocorticoid receptor in hippocampal dentate gyrus reduces immobility in forced swim test. Eur J Pharmacol 301:19-25.
    • (1996) Eur J Pharmacol , vol.301 , pp. 19-25
    • Korte, S.M.1    De Kloet, E.R.2    Buwalda, B.3    Bouman, S.D.4    Bohus, B.5
  • 18
    • 0032508514 scopus 로고    scopus 로고
    • Distinct mechanism for antidepressant activity by blockade of central substance P receptors
    • Kramer MS, Cutler N, Feighner J, Shrivastava R, Carman J, Sramek JJ, et al. (1998). Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 281:1640-1645.
    • (1998) Science , vol.281 , pp. 1640-1645
    • Kramer, M.S.1    Cutler, N.2    Feighner, J.3    Shrivastava, R.4    Carman, J.5    Sramek, J.J.6
  • 19
    • 0024756719 scopus 로고
    • The development of pathological forms of behavior in submissive male C57BL/6J mice during agonistic zoosocial interactions. A possible model of depression?
    • Kudriavtseva NN, Bakshtanovskaia IV, Popova NK (1989). The development of pathological forms of behavior in submissive male C57BL/6J mice during agonistic zoosocial interactions. A possible model of depression? Zh Vyssh Nerv Deiat Im IP Pavlova 39:1134-1141.
    • (1989) Zh Vyssh Nerv Deiat Im IP Pavlova , vol.39 , pp. 1134-1141
    • Kudriavtseva, N.N.1    Bakshtanovskaia, I.V.2    Popova, N.K.3
  • 20
    • 0021619808 scopus 로고
    • The olfactory bulbectomized rat as a model of depression
    • Leonard BE (1984). The olfactory bulbectomized rat as a model of depression. Pol J Pharmacol Pharm 36:561-569.
    • (1984) Pol J Pharmacol Pharm , vol.36 , pp. 561-569
    • Leonard, B.E.1
  • 23
    • 0027435503 scopus 로고
    • Venlafaxine exhibits pre-clinical antidepressant activity in the resident-intruder social interaction paradigm
    • Mitchell PJ, Fletcher A (1993). Venlafaxine exhibits pre-clinical antidepressant activity in the resident-intruder social interaction paradigm. Neuropharmacology 32:1001-1009.
    • (1993) Neuropharmacology , vol.32 , pp. 1001-1009
    • Mitchell, P.J.1    Fletcher, A.2
  • 26
    • 0027223452 scopus 로고
    • Effects of the antiglucocorticoid RU 38486 on the induction of learned helpless behavior in Sprague-Dawley rats
    • Papolos DF, Edwards E, Marmur R, Lachman HM, Henn FA (1993). Effects of the antiglucocorticoid RU 38486 on the induction of learned helpless behavior in Sprague-Dawley rats. Brain Res 615:304-309.
    • (1993) Brain Res , vol.615 , pp. 304-309
    • Papolos, D.F.1    Edwards, E.2    Marmur, R.3    Lachman, H.M.4    Henn, F.A.5
  • 27
    • 0033833835 scopus 로고    scopus 로고
    • The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats
    • Papp M, Vassout A, Gentsch C (2000). The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats. Behav Brain Res 115:19-23.
    • (2000) Behav Brain Res , vol.115 , pp. 19-23
    • Papp, M.1    Vassout, A.2    Gentsch, C.3
  • 28
    • 0035894861 scopus 로고    scopus 로고
    • Exacerbation of pain by anxiety is associated with activity in a hippocampal network
    • Ploghaus A, Narain C, Beckmann CF, Clare S, Bantick S, Wise R, et al. (2001). Exacerbation of pain by anxiety is associated with activity in a hippocampal network. J Neurosci 21:9896-9903.
    • (2001) J Neurosci , vol.21 , pp. 9896-9903
    • Ploghaus, A.1    Narain, C.2    Beckmann, C.F.3    Clare, S.4    Bantick, S.5    Wise, R.6
  • 29
    • 0017651126 scopus 로고
    • Behavioral despair in mice: A primary screening test for antidepressants
    • Porsolt RD, Bertin A, Jalfre M (1977). Behavioral despair in mice: a primary screening test for antidepressants. Arch Int Pharmacodyn Ther 229:327-336.
    • (1977) Arch Int Pharmacodyn Ther , vol.229 , pp. 327-336
    • Porsolt, R.D.1    Bertin, A.2    Jalfre, M.3
  • 31
    • 0028926792 scopus 로고
    • Changes in paroxetine binding in the cerebral cortex of polydipsic rats
    • Roehr J, Woods A, Corbett R, Kongsamut S (1995). Changes in paroxetine binding in the cerebral cortex of polydipsic rats. Eur J Pharmacol 278:75-78.
    • (1995) Eur J Pharmacol , vol.278 , pp. 75-78
    • Roehr, J.1    Woods, A.2    Corbett, R.3    Kongsamut, S.4
  • 34
    • 0027507454 scopus 로고
    • The role of serotonergic mechanisms in inhibition of isolation-induced aggression in male mice
    • Sanchez C, Arnt J, Hyttel J, Moltzen EK (1993). The role of serotonergic mechanisms in inhibition of isolation-induced aggression in male mice. Psychopharmacology 110:53-57.
    • (1993) Psychopharmacology , vol.110 , pp. 53-57
    • Sanchez, C.1    Arnt, J.2    Hyttel, J.3    Moltzen, E.K.4
  • 35
    • 0035498987 scopus 로고    scopus 로고
    • Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: An fMRI study
    • Sheline YI, Barch DM, Donnelly JM, Ollinger JM, Snyder AZ, Mintun MA (2001). Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biol Psychiat 50:651-658.
    • (2001) Biol Psychiat , vol.50 , pp. 651-658
    • Sheline, Y.I.1    Barch, D.M.2    Donnelly, J.M.3    Ollinger, J.M.4    Snyder, A.Z.5    Mintun, M.A.6
  • 36
  • 37
    • 0034768122 scopus 로고    scopus 로고
    • Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function
    • Steinberg R, Alonso R, Griebel G, Bert L, Jung M, Oury-Denat F, et al. (2001). Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function. J Pharmacol Exp Ther 299:449-458.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 449-458
    • Steinberg, R.1    Alonso, R.2    Griebel, G.3    Bert, L.4    Jung, M.5    Oury-Denat, F.6
  • 38
    • 0021990491 scopus 로고
    • The tail suspension test: A new method for screening antidepressants in mice
    • Steru L, Chermat R, Thierry B, Simon P (1985). The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology 85:367-370.
    • (1985) Psychopharmacology , vol.85 , pp. 367-370
    • Steru, L.1    Chermat, R.2    Thierry, B.3    Simon, P.4
  • 39
    • 0033057820 scopus 로고    scopus 로고
    • Hew should efficacy be evaluated in randomized clinical trials of treatments for depression?
    • Thase ME (1999). Hew should efficacy be evaluated in randomized clinical trials of treatments for depression? J Clin Psychiat 60 (suppl 4):23-31.
    • (1999) J Clin Psychiat , vol.60 , Issue.4 SUPPL. , pp. 23-31
    • Thase, M.E.1
  • 40
    • 0020003190 scopus 로고
    • Side effects and placebo amplification
    • Thomson R (1982). Side effects and placebo amplification. Br J Psychiat 140:64-68.
    • (1982) Br J Psychiat , vol.140 , pp. 64-68
    • Thomson, R.1
  • 41
    • 0036428828 scopus 로고    scopus 로고
    • Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites cytogenesis in the dentate gyrus and hippocampal volume
    • van der Hart MG, Czeh B, de Biurrun G, Michaelis T, Watanabe T, Natt O, et al. (2002). Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites cytogenesis in the dentate gyrus and hippocampal volume. Mol Psychiat 7:933-941.
    • (2002) Mol Psychiat , vol.7 , pp. 933-941
    • Van Der Hart, M.G.1    Czeh, B.2    De Biurrun, G.3    Michaelis, T.4    Watanabe, T.5    Natt, O.6
  • 42
    • 0021348560 scopus 로고
    • The validity of animal models of depression
    • Willner P (1984). The validity of animal models of depression. Psychopharmacology 83:1-16.
    • (1984) Psychopharmacology , vol.83 , pp. 1-16
    • Willner, P.1
  • 43
    • 0031440325 scopus 로고    scopus 로고
    • Validity, reliability and utility of the chronic mild stress model of depression: A 10-year review and evaluation
    • Willner P (1997). Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. Psychopharmacology 134:319-329.
    • (1997) Psychopharmacology , vol.134 , pp. 319-329
    • Willner, P.1
  • 44
    • 0036328118 scopus 로고    scopus 로고
    • The validity of animal models of predisposition to depression
    • Willner P, Mitchell PJ (2002). The validity of animal models of predisposition to depression. Behav Pharmacol 13:169-188.
    • (2002) Behav Pharmacol , vol.13 , pp. 169-188
    • Willner, P.1    Mitchell, P.J.2
  • 45
    • 0023636527 scopus 로고
    • Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
    • Willner P, Towell A, Sampson D, Sophokleous S, Muscat R (1987). Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology 93:358-364.
    • (1987) Psychopharmacology , vol.93 , pp. 358-364
    • Willner, P.1    Towell, A.2    Sampson, D.3    Sophokleous, S.4    Muscat, R.5
  • 46
    • 0036678108 scopus 로고    scopus 로고
    • Combining fMRI with a pharmacokinetic model to determine which brain areas activated by painful stimulation are specifically modulated by remifentanil
    • Wise RG, Rogers R, Painter D, Bantick S, Ploghaus A, Williams P, et al. (2002). Combining fMRI with a pharmacokinetic model to determine which brain areas activated by painful stimulation are specifically modulated by remifentanil. Neuroimage 16:999-1014.
    • (2002) Neuroimage , vol.16 , pp. 999-1014
    • Wise, R.G.1    Rogers, R.2    Painter, D.3    Bantick, S.4    Ploghaus, A.5    Williams, P.6
  • 47
    • 0022657442 scopus 로고
    • Psychostimulant treatment of depressive disorders secondary to medical illness
    • Woods SW, Tesar GE, Murray GB, Cassem NH (1986). Psychostimulant treatment of depressive disorders secondary to medical illness. J Clin Psychiat 47:12-15.
    • (1986) J Clin Psychiat , vol.47 , pp. 12-15
    • Woods, S.W.1    Tesar, G.E.2    Murray, G.B.3    Cassem, N.H.4
  • 48
    • 0034193881 scopus 로고    scopus 로고
    • Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: The first 20 patients treated
    • Zobel AW, Nickel T, Kunzel HE, Ackl N, Sonntag A, Ising M, Holsboer F (2000). Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated. J Psychiat Res 34:171-181.
    • (2000) J Psychiat Res , vol.34 , pp. 171-181
    • Zobel, A.W.1    Nickel, T.2    Kunzel, H.E.3    Ackl, N.4    Sonntag, A.5    Ising, M.6    Holsboer, F.7


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