Anxiogenic properties of an inverse agonist selective for α3 subunit-containing GABA A receptors

British Journal of Pharmacology

Volumn 144, Issue 3, 2005, Pages 357-366

  Atack, John R ^a   Hutson, Peter H ^a   Collinson, Neil ^a   Marshall, George ^a   Bentley, Graham ^a   Moyes, Christopher ^a   Cook, Susan M ^a   Collins, Ian ^a   Wafford, Keith ^a   McKernan, Ruth M ^a   Dawson, Gerard R ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

3,4 Dihydroxyphenylacetic acid; Anxiety; Anxiogenic; Benzodiazepine; GABA A receptor; Inverse agonist

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; 6 (4 PYRIDYL) 5 (4 METHOXYPHENYL) 3 CARBOMETHYL 1 METHYL 1H PYRIDIN 2 ONE; FLUMAZENIL; N METHYL BETA CARBOLINE 3 CARBOXAMIDE; PYRIDONE DERIVATIVE; RECEPTOR SUBUNIT; TRITIUM; UNCLASSIFIED DRUG;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; CEREBELLUM; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HUMAN; IMMOBILIZATION STRESS; MALE; MAZE TEST; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RECEPTOR OCCUPANCY;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; ANXIETY; BRAIN CHEMISTRY; CARBOLINES; CEREBELLUM; FIBROBLASTS; GABA AGONISTS; HUMANS; MALE; MICE; PATCH-CLAMP TECHNIQUES; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; SPINAL CORD;

EID: 20044375722     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706056     Document Type: Article

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