-
1
-
-
0032568802
-
Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development
-
Ahmed, Y., Hayashi, S., Levine, A. and Wieschaus, E. (1998). Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development. Cell 93, 1171-1182.
-
(1998)
Cell
, vol.93
, pp. 1171-1182
-
-
Ahmed, Y.1
Hayashi, S.2
Levine, A.3
Wieschaus, E.4
-
2
-
-
0036339813
-
Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development
-
Ahmed, Y., Nouri, A. and Wieschaus, E. (2002). Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development. Development 129, 1751-1762.
-
(2002)
Development
, vol.129
, pp. 1751-1762
-
-
Ahmed, Y.1
Nouri, A.2
Wieschaus, E.3
-
3
-
-
33845352555
-
Wnt signalling and the actin cytoskeleton
-
Akiyama, T. and Kawasaki, Y. (2006). Wnt signalling and the actin cytoskeleton. Oncogene 25, 7538-7544.
-
(2006)
Oncogene
, vol.25
, pp. 7538-7544
-
-
Akiyama, T.1
Kawasaki, Y.2
-
4
-
-
0036389796
-
Drosophila. APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs
-
Akong, K., Grevengoed, E. E., Price, M. H., McCartney, B. M., Hayden, M. A., DeNofrio, J. C. and Peifer, M. (2002a). Drosophila. APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs. Dev. Biol. 250, 91-100.
-
(2002)
Dev. Biol
, vol.250
, pp. 91-100
-
-
Akong, K.1
Grevengoed, E.E.2
Price, M.H.3
McCartney, B.M.4
Hayden, M.A.5
DeNofrio, J.C.6
Peifer, M.7
-
5
-
-
0036387184
-
Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations
-
Akong, K., McCartney, B. M. and Peifer, M. (2002b). Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Dev. Biol. 250, 71-90.
-
(2002)
Dev. Biol
, vol.250
, pp. 71-90
-
-
Akong, K.1
McCartney, B.M.2
Peifer, M.3
-
6
-
-
33847024023
-
Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human
-
Alberici, P., de Pater, E., Cardoso, J., Bevelander, M., Molenaar, L., Jonkers, J. and Fodde, R. (2007). Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human. Am. J. Pathol. 170, 377-387.
-
(2007)
Am. J. Pathol
, vol.170
, pp. 377-387
-
-
Alberici, P.1
de Pater, E.2
Cardoso, J.3
Bevelander, M.4
Molenaar, L.5
Jonkers, J.6
Fodde, R.7
-
7
-
-
20244387973
-
Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine
-
Andrea, F., Colnot, S., Godard, C., Gad, S., Chafey, P., Niwa-Kawaldta, M., Laurent-Puig, F., Kahn, A., Robine, S., Perret, C. et al. (2005). Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine. Development 132, 1443-1451.
-
(2005)
Development
, vol.132
, pp. 1443-1451
-
-
Andrea, F.1
Colnot, S.2
Godard, C.3
Gad, S.4
Chafey, P.5
Niwa-Kawaldta, M.6
Laurent-Puig, F.7
Kahn, A.8
Robine, S.9
Perret, C.10
-
8
-
-
34249323787
-
Chromosomal instability by β-catenin/TCF transcription in APC or β-catenin mutant cells
-
Aoki, K., Aoki, M., Sugai, M., Harada, N., Miyoshi, H., Tsukamoto, T., Mizoshita, T., Tatematsu, M., Seno, H., Chiba, T. et al. (2007). Chromosomal instability by β-catenin/TCF transcription in APC or β-catenin mutant cells. Oncogene 26, 3511-3520.
-
(2007)
Oncogene
, vol.26
, pp. 3511-3520
-
-
Aoki, K.1
Aoki, M.2
Sugai, M.3
Harada, N.4
Miyoshi, H.5
Tsukamoto, T.6
Mizoshita, T.7
Tatematsu, M.8
Seno, H.9
Chiba, T.10
-
9
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
Barker, N. and Clevers, H. (2006). Mining the Wnt pathway for cancer therapeutics. Nat. Rev. Drug Discov. 5, 997-1014.
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
10
-
-
18644376279
-
β-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
-
Batlle, E., Henderson, J. T., Beghtel, H., van den Born, M. M., Sancho, E., Hulls, G., Meeldijk, J, Robertson, J., van de Wetering, M., Pawson, T. et al. (2002). β-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 111, 251-263.
-
(2002)
Cell
, vol.111
, pp. 251-263
-
-
Batlle, E.1
Henderson, J.T.2
Beghtel, H.3
van den Born, M.M.4
Sancho, E.5
Hulls, G.6
Meeldijk, J.7
Robertson, J.8
van de Wetering, M.9
Pawson, T.10
-
11
-
-
0029928160
-
APC gene: Database of germline and somatic mutations in human tumors and cell lines
-
Beroud, C. and Soussi, T. (1996). APC gene: database of germline and somatic mutations in human tumors and cell lines. Nucleic Acids Res. 24, 121-124.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 121-124
-
-
Beroud, C.1
Soussi, T.2
-
12
-
-
0036270763
-
The subcellular destinations of APC proteins
-
Bienz, M. (2002). The subcellular destinations of APC proteins. Nat. Rev. Mol. Cell Biol. 3, 328-338.
-
(2002)
Nat. Rev. Mol. Cell Biol
, vol.3
, pp. 328-338
-
-
Bienz, M.1
-
13
-
-
4444240943
-
Adenomatous polyposis coli proteins and cell adhesion
-
Bienz, M. and Hamada, F. (2004). Adenomatous polyposis coli proteins and cell adhesion. Curr. Opin. Cell Biol. 16, 528-535.
-
(2004)
Curr. Opin. Cell Biol
, vol.16
, pp. 528-535
-
-
Bienz, M.1
Hamada, F.2
-
14
-
-
0029066824
-
Adherens junction proteins in tumour progression
-
Birchmeier, W., Hulsken, J. and Behrens, J. (1995). Adherens junction proteins in tumour progression. Cancer Surv. 24, 129-140.
-
(1995)
Cancer Surv
, vol.24
, pp. 129-140
-
-
Birchmeier, W.1
Hulsken, J.2
Behrens, J.3
-
15
-
-
0037370137
-
Pathology of mouse models of intestinal cancer: Consensus report and recommendations
-
Boivin, G. P., Washington, K., Yang, K., Ward, J. M., Pretlow, T. P., Russell, R., Besselsen, D. G., Godfrey, V. L., Doetschman, T., Dove, W. F. et al. (2003). Pathology of mouse models of intestinal cancer: consensus report and recommendations. Gastroenterology 124, 762-777.
-
(2003)
Gastroenterology
, vol.124
, pp. 762-777
-
-
Boivin, G.P.1
Washington, K.2
Yang, K.3
Ward, J.M.4
Pretlow, T.P.5
Russell, R.6
Besselsen, D.G.7
Godfrey, V.L.8
Doetschman, T.9
Dove, W.F.10
-
16
-
-
0035034603
-
Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
-
Brault, V., Moore, R., Kutsch, S., Ishibasi, M., Rowitch, D. H., McMahon, A. P., Sommer, L., Boussadia, O. and Kemler, R. (2001). Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128, 1253-1264.
-
(2001)
Development
, vol.128
, pp. 1253-1264
-
-
Brault, V.1
Moore, R.2
Kutsch, S.3
Ishibasi, M.4
Rowitch, D.H.5
McMahon, A.P.6
Sommer, L.7
Boussadia, O.8
Kemler, R.9
-
17
-
-
0043093686
-
IQGAP proteins are integral components of cytoskeletal regulation
-
Briggs, M. W. and Socks, D. B. (2003). IQGAP proteins are integral components of cytoskeletal regulation. EMBO Rep. 4, 571-574.
-
(2003)
EMBO Rep
, vol.4
, pp. 571-574
-
-
Briggs, M.W.1
Socks, D.B.2
-
18
-
-
0035914414
-
Progressive changes in adherents junction structure during intestinal adenoma formation in Apc mutant mice
-
Carothers, A. M., Melstrom, K. A., Jr, Mueller, J. D., Weyant, M. J. and Bertagnolli, M. M. (2001). Progressive changes in adherents junction structure during intestinal adenoma formation in Apc mutant mice. J. Biol. Chem. 276, 39094-39102.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 39094-39102
-
-
Carothers, A.M.1
Melstrom Jr, K.A.2
Mueller, J.D.3
Weyant, M.J.4
Bertagnolli, M.M.5
-
19
-
-
1642499734
-
β-Catenin is dispensable for hematopoiesis and lymphopoiesis
-
Cobas, M., Wilson, A., Ernst, B., Mancini, S. J., MacDonald, H. R., Kemler, R. and Radtke, F. (2004). β-Catenin is dispensable for hematopoiesis and lymphopoiesis. J. Exp. Med. 199, 221-229.
-
(2004)
J. Exp. Med
, vol.199
, pp. 221-229
-
-
Cobas, M.1
Wilson, A.2
Ernst, B.3
Mancini, S.J.4
MacDonald, H.R.5
Kemler, R.6
Radtke, F.7
-
20
-
-
2542452815
-
The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts
-
Dikovskaya, D., Newton, I. P. and Nutlike, I. S. (2004). The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts. Mol. Biol. Cell 15, 2978-2991.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2978-2991
-
-
Dikovskaya, D.1
Newton, I.P.2
Nutlike, I.S.3
-
21
-
-
33846419846
-
Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis
-
Dikovskaya, D., Schiffmann, D., Newton, I. P., Oakley, A., Kroboth, K., Jamieson, T. J., Meniel, V., Clarke, A., Sansom, O. and Nathke, I. S. (2007). Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. J. Cell Biol. 176, 193-195.
-
(2007)
J. Cell Biol
, vol.176
, pp. 193-195
-
-
Dikovskaya, D.1
Schiffmann, D.2
Newton, I.P.3
Oakley, A.4
Kroboth, K.5
Jamieson, T.J.6
Meniel, V.7
Clarke, A.8
Sansom, O.9
Nathke, I.S.10
-
22
-
-
33745542004
-
Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells
-
Dravjam, V. M., Shapiro, L., Aldridge, B. and Sorger, P. K. (2006). Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells. EMBO J. 25, 2814-2827.
-
(2006)
EMBO J
, vol.25
, pp. 2814-2827
-
-
Dravjam, V.M.1
Shapiro, L.2
Aldridge, B.3
Sorger, P.K.4
-
23
-
-
0842323788
-
Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion
-
Faux, M. C., Ross, J. L., Meeker, C., Johns, T., Ji, H., Simpson, R. J., Layton, M. J. and Burgess, A. W. (2004). Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion. J. Cell Sci. 117, 427-439.
-
(2004)
J. Cell Sci
, vol.117
, pp. 427-439
-
-
Faux, M.C.1
Ross, J.L.2
Meeker, C.3
Johns, T.4
Ji, H.5
Simpson, R.J.6
Layton, M.J.7
Burgess, A.W.8
-
24
-
-
0028567875
-
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
-
Fodde, R., Edelmann, W., Yang, K., van Leeuwen, C., Carlson, C., Renault, B., Breukel, C., Alt, E., Lipkin, M., Khan, P.. M. et al. (1994). A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc. Natl. Acad. Sci. USA 91, 8969-8973.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
Edelmann, W.2
Yang, K.3
van Leeuwen, C.4
Carlson, C.5
Renault, B.6
Breukel, C.7
Alt, E.8
Lipkin, M.9
Khan, P.M.10
-
25
-
-
0035070046
-
Mutations in the APC tumour suppressor gene cause chromosomal instability
-
Forlde, R., Kuipers, J., Rosenberg, C., Smits, R., Kielman, M., Gaspar, C., van Es, J. H., Breukel, C., Wiegant, J., Giles, R. H. et al. (2001). Mutations in the APC tumour suppressor gene cause chromosomal instability. Nat. Cell Biol. 3, 433-438.
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 433-438
-
-
Forlde, R.1
Kuipers, J.2
Rosenberg, C.3
Smits, R.4
Kielman, M.5
Gaspar, C.6
van Es, J.H.7
Breukel, C.8
Wiegant, J.9
Giles, R.H.10
-
26
-
-
0032567078
-
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin
-
Gat, U., DasGupta, R., Degenstein, L. and Fuchs, E. (1998). De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin. Cell 95, 605-614.
-
(1998)
Cell
, vol.95
, pp. 605-614
-
-
Gat, U.1
DasGupta, R.2
Degenstein, L.3
Fuchs, E.4
-
27
-
-
12944329959
-
Chromosomal breakage-fusion-bridge events cause genetic imratumor heterogeneity
-
Gisselsson, D., Pettersson, L., Hoglund, M., Heidenblad, M., Gorunova, L., Wiegant, J., Mertens, F., Dal Cin, F., Mitelman, F. and Mandahl, N. (2000). Chromosomal breakage-fusion-bridge events cause genetic imratumor heterogeneity. Proc. Natl. Acad. Sci. USA 97, 5357-5362.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5357-5362
-
-
Gisselsson, D.1
Pettersson, L.2
Hoglund, M.3
Heidenblad, M.4
Gorunova, L.5
Wiegant, J.6
Mertens, F.7
Dal Cin, F.8
Mitelman, F.9
Mandahl, N.10
-
28
-
-
20244373613
-
-
Glass, D. A., 2nd, Bialek, P., Ahn, J. D., Starbuck, M., Patel, M. S., Clevers, H., Taketo, M. M., Long, F., McMahon, A. P., Lang, R. A. et al. (2005). Canonical Writ signaling in differentiated osteoblasts controls osteoclast differentiation. Dev. Cell 8, 751-764.
-
Glass, D. A., 2nd, Bialek, P., Ahn, J. D., Starbuck, M., Patel, M. S., Clevers, H., Taketo, M. M., Long, F., McMahon, A. P., Lang, R. A. et al. (2005). Canonical Writ signaling in differentiated osteoblasts controls osteoclast differentiation. Dev. Cell 8, 751-764.
-
-
-
-
29
-
-
23944472219
-
Loss of adenomatous polyposis coli gene function disrupts thymic development
-
Gounari, F., Chang, R., Cowan, J., Gun, Z., Dose, M., Gounaris, E. and Khazaie, K. (2005). Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat. Immunol. 6, 800-809.
-
(2005)
Nat. Immunol
, vol.6
, pp. 800-809
-
-
Gounari, F.1
Chang, R.2
Cowan, J.3
Gun, Z.4
Dose, M.5
Gounaris, E.6
Khazaie, K.7
-
30
-
-
0346849717
-
Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC
-
Green, R. A. and Kaplan, K. B. (2003). Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC. J. Cell Biol. 163, 949-961.
-
(2003)
J. Cell Biol
, vol.163
, pp. 949-961
-
-
Green, R.A.1
Kaplan, K.B.2
-
31
-
-
26244463198
-
APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment
-
Green, R. A., Wollman, R. and Kaplan, K. B. (2005). APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment. Mol. Biol. Cell 16, 4609-4622.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4609-4622
-
-
Green, R.A.1
Wollman, R.2
Kaplan, K.B.3
-
32
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden, J., Thliveris, A., Samowitz, W., Carlson, M., Gelbert, L., Albertsen, H., Joslyn, G., Stevens, J., Spirio, L., Robertson, M. et al. (1991). Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66, 589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
Albertsen, H.6
Joslyn, G.7
Stevens, J.8
Spirio, L.9
Robertson, M.10
-
33
-
-
33746096996
-
Aberrant Wnt/β-catenin signaling can induce chromosomal instability in colon cancer
-
Hadjihannas, M. V., Bruckner, M., Jerchow, B., Birchmeier, W., Dietmaier, W. and Behrens, J. (2006). Aberrant Wnt/β-catenin signaling can induce chromosomal instability in colon cancer. Proc. Natl. Acad. Sci. USA 103, 10747-10752.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 10747-10752
-
-
Hadjihannas, M.V.1
Bruckner, M.2
Jerchow, B.3
Birchmeier, W.4
Dietmaier, W.5
Behrens, J.6
-
34
-
-
0036125041
-
A Drosophila APC turnour suppressor homologue functions in cellular adhesion
-
Hamada, F. and Bienz, M. (2002). A Drosophila APC turnour suppressor homologue functions in cellular adhesion. Nat. Cell Biol. 4, 208-213.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 208-213
-
-
Hamada, F.1
Bienz, M.2
-
35
-
-
7744246985
-
The APC tumor suppressor binds to C-terminal binding protein to divert nuclear β-catenin from TCF
-
Hamada, F. and Bienz, M. (2004). The APC tumor suppressor binds to C-terminal binding protein to divert nuclear β-catenin from TCF. Dev. Cell 7, 677-685.
-
(2004)
Dev. Cell
, vol.7
, pp. 677-685
-
-
Hamada, F.1
Bienz, M.2
-
36
-
-
6544276454
-
Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC
-
Hamada, F., Murata, Y., Nishida, A., Fujita, F., Tomoyasu, Y., Nakamura, M., Toyoshima, K., Tabata, T., Ueno, N. and Akiyama, T. (1999). Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC. Genes Cells 4, 465-474.
-
(1999)
Genes Cells
, vol.4
, pp. 465-474
-
-
Hamada, F.1
Murata, Y.2
Nishida, A.3
Fujita, F.4
Tomoyasu, Y.5
Nakamura, M.6
Toyoshima, K.7
Tabata, T.8
Ueno, N.9
Akiyama, T.10
-
37
-
-
33846931753
-
Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element
-
Hamann, M. J., Lubking, C. M., Luchini, D. N. and Billadeau, D. D. (2007). Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element. Mol. Cell. Biol. 27, 1380-1393.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 1380-1393
-
-
Hamann, M.J.1
Lubking, C.M.2
Luchini, D.N.3
Billadeau, D.D.4
-
38
-
-
0033230616
-
Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene
-
Harada, N., Tamai, Y., Ishikawa, T., Sauer, B., Takaku, K., Oshima, M. and Taketo, M. M. (1999). Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene. EMBO J. 18, 5931-5942.
-
(1999)
EMBO J
, vol.18
, pp. 5931-5942
-
-
Harada, N.1
Tamai, Y.2
Ishikawa, T.3
Sauer, B.4
Takaku, K.5
Oshima, M.6
Taketo, M.M.7
-
39
-
-
0031013879
-
A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates β-catenin but its zygotic expression is not essential for the regulation of Armadillo
-
Hayashi, S., Rubinfeld, B., Souza, B., Polakis, P., Wieschaus, E. and Levine, A. J. (1997). A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates β-catenin but its zygotic expression is not essential for the regulation of Armadillo. Proc. Natl. Acad. Sci. USA 94, 242-247.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 242-247
-
-
Hayashi, S.1
Rubinfeld, B.2
Souza, B.3
Polakis, P.4
Wieschaus, E.5
Levine, A.J.6
-
40
-
-
34247176773
-
Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development
-
Hayden, M. A., Akong, K. and Peifer, M. (2007). Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development. Dev. Biol. 305, 358-376.
-
(2007)
Dev. Biol
, vol.305
, pp. 358-376
-
-
Hayden, M.A.1
Akong, K.2
Peifer, M.3
-
41
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He, T. C., Sparks, A. B., Rago, C., Hermeking, H., Zawei, L., da Costa, L. T., Morin, P. J., Vogelstein, B. and Kinzier, K. W. (1998). Identification of c-MYC as a target of the APC pathway. Science 281, 1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawei, L.5
da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzier, K.W.9
-
42
-
-
0036747385
-
The ins and outs of APC and β-catenin nuclear transport
-
Henderson, B. R. and Fagotto, F. (2002). The ins and outs of APC and β-catenin nuclear transport. EMBO Rep. 3, 834-839.
-
(2002)
EMBO Rep
, vol.3
, pp. 834-839
-
-
Henderson, B.R.1
Fagotto, F.2
-
43
-
-
17844363974
-
Canonical Wnt/β-catenin signaling prevents osteoblasts from differentiating into chondrocytes
-
Hill, T. P., Spater, D., Taketo, M. M., Birchmeier, W. and Hartmann, C. (2005). Canonical Wnt/β-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev. Cell 8, 727-738.
-
(2005)
Dev. Cell
, vol.8
, pp. 727-738
-
-
Hill, T.P.1
Spater, D.2
Taketo, M.M.3
Birchmeier, W.4
Hartmann, C.5
-
44
-
-
0035907041
-
β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G. and Birchmeier, W. (2001). β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105, 533-545.
-
(2001)
Cell
, vol.105
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
Cotsarelis, G.4
Birchmeier, W.5
-
45
-
-
0037440378
-
Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo
-
Ishikawa, T. O., Tumai, Y., Li, Q., Oshima, M. and Taketo, M. M. (2003). Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo. Dev. Biol. 253, 230-246.
-
(2003)
Dev. Biol
, vol.253
, pp. 230-246
-
-
Ishikawa, T.O.1
Tumai, Y.2
Li, Q.3
Oshima, M.4
Taketo, M.M.5
-
46
-
-
0035067391
-
A role for the Adenomatous Polyposis Coli protein in chromosome segregation
-
Kaplan, K. B., Burds, A. A., Swedlow, J. R., Bekir, S. S., Sorger, P. K. and Nathke, I. S. (2001). A role for the Adenomatous Polyposis Coli protein in chromosome segregation. Nat. Cell Biol. 3, 429-432.
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 429-432
-
-
Kaplan, K.B.1
Burds, A.A.2
Swedlow, J.R.3
Bekir, S.S.4
Sorger, P.K.5
Nathke, I.S.6
-
47
-
-
0034682888
-
Asef, a link between the tumor suppressor APC and G-protein signaling
-
Kawasaki, Y., Senda, T., Ishidate, T., Koyama, R., Morishita, T., Iwayama, Y., Higuchi, O. and Akiyama, T. (2000). Asef, a link between the tumor suppressor APC and G-protein signaling. Science 289, 1194-1197.
-
(2000)
Science
, vol.289
, pp. 1194-1197
-
-
Kawasaki, Y.1
Senda, T.2
Ishidate, T.3
Koyama, R.4
Morishita, T.5
Iwayama, Y.6
Higuchi, O.7
Akiyama, T.8
-
48
-
-
0037341566
-
Mutated APC and Asef are involved in the migration of colorectal tumour cells
-
Kawasaki, Y., Sato, R. and Aldyama, T. (2003). Mutated APC and Asef are involved in the migration of colorectal tumour cells. Nat. Cell Biol. 5, 211-215.
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 211-215
-
-
Kawasaki, Y.1
Sato, R.2
Aldyama, T.3
-
49
-
-
0027185632
-
From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
-
Kemler, R. (1993). From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9, 317-321.
-
(1993)
Trends Genet
, vol.9
, pp. 317-321
-
-
Kemler, R.1
-
50
-
-
18744398990
-
Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catcniin signaling
-
Kleiman, M. F., Rindapaa, M., Gaspar, C., van Poppel, N., Breukel, C., van Leeuwen, S., Taketo, M. M., Roberts, S., Smits, R. and Fuddle, R. (2002). Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catcniin signaling. Nat. Genet. 32, 594-605.
-
(2002)
Nat. Genet
, vol.32
, pp. 594-605
-
-
Kleiman, M.F.1
Rindapaa, M.2
Gaspar, C.3
van Poppel, N.4
Breukel, C.5
van Leeuwen, S.6
Taketo, M.M.7
Roberts, S.8
Smits, R.9
Fuddle, R.10
-
51
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler, K. W. and Vogelstein, B. (1996). Lessons from hereditary colorectal cancer. Cell 87, 159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
52
-
-
0025909734
-
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers
-
Kinzler, K. W., Nilbert, M. C., Vogelstein, B., Bryan, T. M., Levy, D. B., Smith, K. J., Preisinger, A. C., Hamilton, S. R., Hedge, P., Markham, A. et al. (1991). Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science 251, 1366-1370.
-
(1991)
Science
, vol.251
, pp. 1366-1370
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Vogelstein, B.3
Bryan, T.M.4
Levy, D.B.5
Smith, K.J.6
Preisinger, A.C.7
Hamilton, S.R.8
Hedge, P.9
Markham, A.10
-
53
-
-
33748850636
-
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
-
Kirstetter, P., Anderson, K., Purse, B. T., Jacobsen, S. E. and Nerlov, C. (2006). Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat. Immunol. 7, 1048-1056.
-
(2006)
Nat. Immunol
, vol.7
, pp. 1048-1056
-
-
Kirstetter, P.1
Anderson, K.2
Purse, B.T.3
Jacobsen, S.E.4
Nerlov, C.5
-
54
-
-
34047138860
-
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion
-
Kitamura, T., Kometani, K., Hashida, H., Matsunaga, A, Miyoshi, H., Hosogi, H., Aoki, M., Oshima, M., Hattori, M., Takabayashi, A. et al. (2007). SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nat. Genet. 39, 467-475.
-
(2007)
Nat. Genet
, vol.39
, pp. 467-475
-
-
Kitamura, T.1
Kometani, K.2
Hashida, H.3
Matsunaga, A.4
Miyoshi, H.5
Hosogi, H.6
Aoki, M.7
Oshima, M.8
Hattori, M.9
Takabayashi, A.10
-
55
-
-
18544390370
-
Neural crest stem cell maintenance by combinatorial Writ and BMP signaling
-
Kleber, M., Lee, H. Y., Wurdak, H., Buchstaller, J., Riccomagno, M. M., Ittmer, L. M., Suter, U., Epstein, D. J. and Sommer, L. (2005). Neural crest stem cell maintenance by combinatorial Writ and BMP signaling. J. Cell Biol. 169, 309-320.
-
(2005)
J. Cell Biol
, vol.169
, pp. 309-320
-
-
Kleber, M.1
Lee, H.Y.2
Wurdak, H.3
Buchstaller, J.4
Riccomagno, M.M.5
Ittmer, L.M.6
Suter, U.7
Epstein, D.J.8
Sommer, L.9
-
56
-
-
0030975671
-
-/- colon carcinoma
-
-/- colon carcinoma. Science 275, 1784-1787.
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, F.J.3
van Wichen, D.4
de Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
57
-
-
33947177629
-
Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability
-
Kroboth, K., Newton, I. P., Kita, K., Dikovskaya, D., Zumbrunn, J., Waterman-Storer, C. M. and Nathke, I. S. (2007). Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability. Mol. Biol. Cell 18, 910-918.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 910-918
-
-
Kroboth, K.1
Newton, I.P.2
Kita, K.3
Dikovskaya, D.4
Zumbrunn, J.5
Waterman-Storer, C.M.6
Nathke, I.S.7
-
58
-
-
1842479447
-
Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes
-
Louie, R. K., Bahmanyar, S., Siemers, K. A., Votin, V., Chang, P., Stearns, T., Nelson, W. J. and Barth, A. I. (2004). Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes. J. Cell Sci. 117, 1117-1128.
-
(2004)
J. Cell Sci
, vol.117
, pp. 1117-1128
-
-
Louie, R.K.1
Bahmanyar, S.2
Siemers, K.A.3
Votin, V.4
Chang, P.5
Stearns, T.6
Nelson, W.J.7
Barth, A.I.8
-
59
-
-
0030703623
-
Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration
-
Mahmoud, N. N., Boolhol, S. K., Bilinski, R. T., Martucci, C., Chadburn, A. and Bertagnolli, M. M. (1997). Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration. Cancer Res. 57, 5045-5050.
-
(1997)
Cancer Res
, vol.57
, pp. 5045-5050
-
-
Mahmoud, N.N.1
Boolhol, S.K.2
Bilinski, R.T.3
Martucci, C.4
Chadburn, A.5
Bertagnolli, M.M.6
-
60
-
-
0033588939
-
Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis
-
McCartney, B. M., Dierick, H. A., Kirkpatrick, C., Moline, M. M., Baas, A., Peifer, M. and Bcjsovec, A. (1999). Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis. J. Cell Biol. 146, 1303-1318.
-
(1999)
J. Cell Biol
, vol.146
, pp. 1303-1318
-
-
McCartney, B.M.1
Dierick, H.A.2
Kirkpatrick, C.3
Moline, M.M.4
Baas, A.5
Peifer, M.6
Bcjsovec, A.7
-
61
-
-
0034789121
-
Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin
-
McCartney, B. M., McEwen, D. G., Grevengoed, E., Maddox, P., Bejsovec, A. and Peifer, M. (2001). Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin. Nat. Cell Biol. 3, 933-938.
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 933-938
-
-
McCartney, B.M.1
McEwen, D.G.2
Grevengoed, E.3
Maddox, P.4
Bejsovec, A.5
Peifer, M.6
-
62
-
-
33745919542
-
Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila
-
McCartney, B. M., Price, M. H., Webb, R. L., Hayden, M. A., Holot, L. M., Zhou, M., Bejsovec, A. and Peifer, M. (2006). Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. Development 133, 2407-2418.
-
(2006)
Development
, vol.133
, pp. 2407-2418
-
-
McCartney, B.M.1
Price, M.H.2
Webb, R.L.3
Hayden, M.A.4
Holot, L.M.5
Zhou, M.6
Bejsovec, A.7
Peifer, M.8
-
63
-
-
0031006251
-
APC expression in normal human tissues
-
Midgley, C. A., White, S., Howitt, R., Save, V., Dunlop, M. G., Hall, P. A., Lane, D. F., Wyllie, A. H. and Bubb, V. J. (1997). APC expression in normal human tissues. J. Pathol. 181, 426-433.
-
(1997)
J. Pathol
, vol.181
, pp. 426-433
-
-
Midgley, C.A.1
White, S.2
Howitt, R.3
Save, V.4
Dunlop, M.G.5
Hall, P.A.6
Lane, D.F.7
Wyllie, A.H.8
Bubb, V.J.9
-
64
-
-
0029102368
-
Subcellular localization of the APC protein: Immunoelectron microscopic study of the association of the APC protein with catenin
-
Miyashiro, I., Senda, T., Matsumine, A., Baeg, G. H., Kuroda, T., Shimano, T., Miura, S., Noda, T., Kobayashi, S., Monden, M. et al. (1995). Subcellular localization of the APC protein: immunoelectron microscopic study of the association of the APC protein with catenin. Oncogene 11, 89-96.
-
(1995)
Oncogene
, vol.11
, pp. 89-96
-
-
Miyashiro, I.1
Senda, T.2
Matsumine, A.3
Baeg, G.H.4
Kuroda, T.5
Shimano, T.6
Miura, S.7
Noda, T.8
Kobayashi, S.9
Monden, M.10
-
65
-
-
0030949463
-
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
-
Morin, P. J., Sparks, A. B., Korinek, V., Barker, N., Clevers, H., Vogelstein, B. and Kinzler, K. W. (1997). Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 275, 1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
66
-
-
0032585647
-
EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle
-
Morrison, E. E., Wardleworth, B. N., Askham, J. M., Markham, A. F. and Meredith, D. M. (1999). EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle. Oncogene 17, 3471-3477.
-
(1999)
Oncogene
, vol.17
, pp. 3471-3477
-
-
Morrison, E.E.1
Wardleworth, B.N.2
Askham, J.M.3
Markham, A.F.4
Meredith, D.M.5
-
67
-
-
34250347751
-
Regulated binding of Adenomatous polyposis coli protein to actin
-
Moseley, J. B., Bartolini, F., Okada, K., Wen, Y., Gundersen, G. G. and Goode, B. L. (2007). Regulated binding of Adenomatous polyposis coli protein to actin. J. Biol. Chem. 282, 12661-12668.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 12661-12668
-
-
Moseley, J.B.1
Bartolini, F.2
Okada, K.3
Wen, Y.4
Gundersen, G.G.5
Goode, B.L.6
-
68
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser, A. R., Pitot, H. C. and Dove, W. F. (1990). A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247, 322-324.
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.F.3
-
69
-
-
0029125021
-
Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation
-
Moser, A. R., Shoemaker, A. R., Connelly, C. S., Clipson, L., Gould, K. A., Luongo, C., Dove, W. F., Siggers, P. H. and Gardner, R. L. (1995). Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation. Dev. Dyn. 203, 422-433.
-
(1995)
Dev. Dyn
, vol.203
, pp. 422-433
-
-
Moser, A.R.1
Shoemaker, A.R.2
Connelly, C.S.3
Clipson, L.4
Gould, K.A.5
Luongo, C.6
Dove, W.F.7
Siggers, P.H.8
Gardner, R.L.9
-
70
-
-
0027930066
-
The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
-
Munemitsu, S., Souza, B., Muller, O., Albert, L, Rubinfeld, B. and Polakis, P. (1994). The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res. 54, 3676-3681.
-
(1994)
Cancer Res
, vol.54
, pp. 3676-3681
-
-
Munemitsu, S.1
Souza, B.2
Muller, O.3
Albert, L.4
Rubinfeld, B.5
Polakis, P.6
-
71
-
-
0035838422
-
Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization
-
Nakamura, M., Zhou, X. Z. and Lu. K. P. (2001). Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization. Curr. Biol. 11, 1062-1067.
-
(2001)
Curr. Biol
, vol.11
, pp. 1062-1067
-
-
Nakamura, M.1
Zhou, X.Z.2
Lu, K.P.3
-
72
-
-
8444236025
-
The adenomatous polyposis coli protein: The achilles heel of the gut epithelium
-
Nathke, I. S. (2004). The adenomatous polyposis coli protein: the achilles heel of the gut epithelium. Annu. Rev. Cell Dev. Biol. 20, 337-366.
-
(2004)
Annu. Rev. Cell Dev. Biol
, vol.20
, pp. 337-366
-
-
Nathke, I.S.1
-
73
-
-
33845234807
-
Cytoskeleton out of the cupboard: Colon cancer and cytoskeletal changes induced by loss of APC
-
Nathke, I. (2006). Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC. Nat. Rev. Cancer 6, 967-974.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 967-974
-
-
Nathke, I.1
-
74
-
-
0029982877
-
The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration
-
Nathke, I. S., Adams, C. L., Polakis, P., Sellin, J. H. and Nelson, W. J. (1996). The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration. J. Cell Biol. 134, 165-179.
-
(1996)
J. Cell Biol
, vol.134
, pp. 165-179
-
-
Nathke, I.S.1
Adams, C.L.2
Polakis, P.3
Sellin, J.H.4
Nelson, W.J.5
-
75
-
-
0034576628
-
APC-mediated downregulation of β-catenin activity involves nuclear sequestration and nuclear export
-
Neufeld, K. L., Zhang, F., Cullen, B. R. and White, R. L. (2000). APC-mediated downregulation of β-catenin activity involves nuclear sequestration and nuclear export. EMBO Rep. 1, 519-523.
-
(2000)
EMBO Rep
, vol.1
, pp. 519-523
-
-
Neufeld, K.L.1
Zhang, F.2
Cullen, B.R.3
White, R.L.4
-
76
-
-
33749065765
-
Tcf3 governs stem cell features and represses cell fate determination in skin
-
Nguyen, H., Rendl, M. and Fuchs, E. (2006). Tcf3 governs stem cell features and represses cell fate determination in skin. Cell 127, 171-183.
-
(2006)
Cell
, vol.127
, pp. 171-183
-
-
Nguyen, H.1
Rendl, M.2
Fuchs, E.3
-
77
-
-
21044443326
-
IQGAP1: A key regulator of adhesion and migration
-
Noritake, J., Watanabe, T., Sato, K., Wang, S. and Kaibuchu, K. (2005). IQGAP1: a key regulator of adhesion and migration. J. Cell Sci. 118, 2085-2092.
-
(2005)
J. Cell Sci
, vol.118
, pp. 2085-2092
-
-
Noritake, J.1
Watanabe, T.2
Sato, K.3
Wang, S.4
Kaibuchu, K.5
-
78
-
-
0038107468
-
β-Catenin regulation during the cell cycle: Implications in G2/M and apoptosis
-
Olmeda, D., Castel, S., Vilaro, S. and Cano, A. (2003). β-Catenin regulation during the cell cycle: implications in G2/M and apoptosis. Mol. Biol. Cell 14, 2844-2860.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 2844-2860
-
-
Olmeda, D.1
Castel, S.2
Vilaro, S.3
Cano, A.4
-
80
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal fissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima, M., Oshima, H., Kitagawa, K., Kobayashi, M., Itakura, C. and Taketo, M. (1995). Loss of Apc heterozygosity and abnormal fissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc. Natl. Acad. Sci. USA 92, 4482-4486.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kitagawa, K.3
Kobayashi, M.4
Itakura, C.5
Taketo, M.6
-
81
-
-
0031557898
-
The adenomatous polyposis coli (APC) tumor suppressor
-
Polakis, P. (1997). The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta 1332, F127-F147.
-
(1997)
Biochim. Biophys. Acta
, vol.1332
-
-
Polakis, P.1
-
82
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell, S. M., Zilz, N., Beazer-Barclay, Y., Bryan, T. M., Hamilton, S. R., Thibodeau, S. N., Vogelstein, B. and Kinzler, K. W. (1992). APC mutations occur early during colorectal tumorigenesis. Nature 359, 235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
83
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya, T. and Clevers, H. (2005). Wnt signalling in stem cells and cancer. Nature 434, 843-850.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
84
-
-
0037416148
-
Nuclear export of the APC tumour suppressor controls β-catenin function in transcription
-
Rosin-Arbesfeld, R., Cliffe, A., Brabletz, T. and Bienz, M. (2003). Nuclear export of the APC tumour suppressor controls β-catenin function in transcription. EMBO J. 22, 1101-1113.
-
(2003)
EMBO J
, vol.22
, pp. 1101-1113
-
-
Rosin-Arbesfeld, R.1
Cliffe, A.2
Brabletz, T.3
Bienz, M.4
-
85
-
-
0027738023
-
Association of the APC gene product with β-catenin
-
Rubinfeld, B., Souza, B., Albert, L, Muller, O., Chamberlain, S. H., Masiarz, F. R., Munernitsu, S. and Polakis, F. (1993). Association of the APC gene product with β-catenin. Science 262, 1731-1734.
-
(1993)
Science
, vol.262
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, L.3
Muller, O.4
Chamberlain, S.H.5
Masiarz, F.R.6
Munernitsu, S.7
Polakis, F.8
-
86
-
-
0029664368
-
Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
-
Rubinfeld, B., Albert, I., Porfiri, E., Fiol, C., Munemitsu, S. and Polakis, P. (1996). Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly. Science 272, 1023-1026.
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
87
-
-
2942668475
-
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
-
Sansom, O. J., Reed, K. R., Hayes, A. J., Ireland, H., Brinkmann, H., Newton, I. P., Battle, E., Simon-Assmann, F., Clevers, H., Nathke, I. S. et al. (2004). Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes Dev. 18, 1385-1390.
-
(2004)
Genes Dev
, vol.18
, pp. 1385-1390
-
-
Sansom, O.J.1
Reed, K.R.2
Hayes, A.J.3
Ireland, H.4
Brinkmann, H.5
Newton, I.P.6
Battle, E.7
Simon-Assmann, F.8
Clevers, H.9
Nathke, I.S.10
-
88
-
-
33748859509
-
Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation
-
Scheller, M., Huelsken, J., Rosenbauer, F., Taketo, M. M., Birchmeier, W., Tenen, D. G. and Lentz, A. (2006). Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation. Nat. Immunol. 7, 1037-1047.
-
(2006)
Nat. Immunol
, vol.7
, pp. 1037-1047
-
-
Scheller, M.1
Huelsken, J.2
Rosenbauer, F.3
Taketo, M.M.4
Birchmeier, W.5
Tenen, D.G.6
Lentz, A.7
-
89
-
-
0037168610
-
Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC
-
Sieber, O. M., Heinimann, K., Gorman, F., Lanilum, H., Crabtree, M., Simpson, C. A., Davies, D., Neale, K., Hodgson, S. V., Roylance, R. R. et al. (2002). Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC. Proc. Natl. Acad. Sci. USA 99, 16910-16915.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 16910-16915
-
-
Sieber, O.M.1
Heinimann, K.2
Gorman, F.3
Lanilum, H.4
Crabtree, M.5
Simpson, C.A.6
Davies, D.7
Neale, K.8
Hodgson, S.V.9
Roylance, R.R.10
-
90
-
-
33644763022
-
The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes
-
Sierra, J., Yoshida, T., Joazeiro, C. A. and Jones, K. A. (2006). The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev. 20, 586-600.
-
(2006)
Genes Dev
, vol.20
, pp. 586-600
-
-
Sierra, J.1
Yoshida, T.2
Joazeiro, C.A.3
Jones, K.A.4
-
91
-
-
0027991585
-
Wild-type but not mutant APC associates with the microtubule cytoskeleton
-
Smith, K. J., Levy, D. B., Maupin, P., Pollard, T. D., Vogelstein, B. and Kinzler, K. W. (1994). Wild-type but not mutant APC associates with the microtubule cytoskeleton. Cancer Res. 54, 3672-3675.
-
(1994)
Cancer Res
, vol.54
, pp. 3672-3675
-
-
Smith, K.J.1
Levy, D.B.2
Maupin, P.3
Pollard, T.D.4
Vogelstein, B.5
Kinzler, K.W.6
-
92
-
-
33845986330
-
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
-
Sotillo, R., Hernando, E., Diaz-Rodriguez, E., Teruya-Feldstein, J., Cordon-Cardo, C., Lowe, S. W. and Benezra, R. (2007). Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell 11, 9-23.
-
(2007)
Cancer Cell
, vol.11
, pp. 9-23
-
-
Sotillo, R.1
Hernando, E.2
Diaz-Rodriguez, E.3
Teruya-Feldstein, J.4
Cordon-Cardo, C.5
Lowe, S.W.6
Benezra, R.7
-
93
-
-
0026562404
-
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
-
Su, L. K., Kinzler, K. W., Vogelstein, B., Preisinger, A. C., Moser, A. R., Luongo, C., Gould, K. A. and Dove, W. F. (1992). Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 256, 668-670.
-
(1992)
Science
, vol.256
, pp. 668-670
-
-
Su, L.K.1
Kinzler, K.W.2
Vogelstein, B.3
Preisinger, A.C.4
Moser, A.R.5
Luongo, C.6
Gould, K.A.7
Dove, W.F.8
-
94
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
Su, L. K., Vogelstein, B. and Kinzler, K. W. (1993). Association of the APC tumor suppressor protein with catenins. Science 262, 1734-1737.
-
(1993)
Science
, vol.262
, pp. 1734-1737
-
-
Su, L.K.1
Vogelstein, B.2
Kinzler, K.W.3
-
95
-
-
0029066006
-
APC binds to the novel protein EB1
-
Su, L. K., Burrell, M., Hill, D. E., Gyuris, J., Brent, R., Wiltshire, R., Trent, J., Vogelstein, B. and Kinzler, K. W. (1995). APC binds to the novel protein EB1. Cancer Res. 55, 2972-2977.
-
(1995)
Cancer Res
, vol.55
, pp. 2972-2977
-
-
Su, L.K.1
Burrell, M.2
Hill, D.E.3
Gyuris, J.4
Brent, R.5
Wiltshire, R.6
Trent, J.7
Vogelstein, B.8
Kinzler, K.W.9
-
96
-
-
0032489508
-
-
Takaku, K., Oshima, M., Miyoshi, H., Matsui, M., Seldin, M. E and Taketo, M. M. (1998). Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 92, 645-656.
-
Takaku, K., Oshima, M., Miyoshi, H., Matsui, M., Seldin, M. E and Taketo, M. M. (1998). Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 92, 645-656.
-
-
-
-
97
-
-
33845352215
-
Wnt signaling and gastrointestinal tumorigenesis in mouse models
-
Taketo, M. M. (2006). Wnt signaling and gastrointestinal tumorigenesis in mouse models. Oncogene 25, 7522-7530.
-
(2006)
Oncogene
, vol.25
, pp. 7522-7530
-
-
Taketo, M.M.1
-
98
-
-
18444379938
-
Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis
-
Tan, M., Jing, T., Lan, K. H., Neal, C. L., Li, F., Lee, S., Fang, D, Nagata, Y., Liu, J., Arlinghaus, R. et al. (2002). Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. Mol. Cell 9, 993-1004.
-
(2002)
Mol. Cell
, vol.9
, pp. 993-1004
-
-
Tan, M.1
Jing, T.2
Lan, K.H.3
Neal, C.L.4
Li, F.5
Lee, S.6
Fang, D.7
Nagata, Y.8
Liu, J.9
Arlinghaus, R.10
-
99
-
-
0033119801
-
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu, O. and McCormick, F. (1999). β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398, 422-426.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
100
-
-
0034906435
-
Aneuploid colon cancer cells have a robust spindle checkpoint
-
Tighe, A., Johnson, V. L., Albertella, M. and Taylor, S. S. (2001). Aneuploid colon cancer cells have a robust spindle checkpoint. EMBO Rep. 2, 609-614.
-
(2001)
EMBO Rep
, vol.2
, pp. 609-614
-
-
Tighe, A.1
Johnson, V.L.2
Albertella, M.3
Taylor, S.S.4
-
101
-
-
13444261036
-
Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability
-
Tighe, A., Johnson, V. L. and Taylor, S. S. (2004). Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability. J. Cell Sci. 117, 6339-6353.
-
(2004)
J. Cell Sci
, vol.117
, pp. 6339-6353
-
-
Tighe, A.1
Johnson, V.L.2
Taylor, S.S.3
-
102
-
-
18644373146
-
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering, M., Sancho, E., Verweij, C., de Lau, W., Oving, L, Hurlstone, A., van der Horn, K., Batlle, E., Coudreuse, D., Haramis, A. P. et al. (2002). The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111, 241-250.
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
van de Wetering, M.1
Sancho, E.2
Verweij, C.3
de Lau, W.4
Oving, L.5
Hurlstone, A.6
van der Horn, K.7
Batlle, E.8
Coudreuse, D.9
Haramis, A.P.10
-
103
-
-
0033611574
-
Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor
-
van Es, J. H., Kirkpatrick, C., van de Wetering, M., Molenaar, M., Miles, A., Kuipers, J., Destree, O., Peffer, M. and Clevers, H. (1999). Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. Curr Biol. 9, 105-108.
-
(1999)
Curr Biol
, vol.9
, pp. 105-108
-
-
van Es, J.H.1
Kirkpatrick, C.2
van de Wetering, M.3
Molenaar, M.4
Miles, A.5
Kuipers, J.6
Destree, O.7
Peffer, M.8
Clevers, H.9
-
104
-
-
0035835826
-
The many fares of the tumor suppressor gene APC
-
van Es, J. H., Giles, R. H. and Clevers, H. C. (2001). The many fares of the tumor suppressor gene APC. Exp. Cell Res. 264, 126-134.
-
(2001)
Exp. Cell Res
, vol.264
, pp. 126-134
-
-
van Es, J.H.1
Giles, R.H.2
Clevers, H.C.3
-
105
-
-
10644281068
-
Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration
-
Watanabe, T., Wang, S., Noritake, J., Sato, K., Fukata, M., Takefuji, M., Nakagawa, M., Izumi, N., Akiyama, T. and Kaibuchi, K. (2004). Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration. Dev. Cell 7, 871-883.
-
(2004)
Dev. Cell
, vol.7
, pp. 871-883
-
-
Watanabe, T.1
Wang, S.2
Noritake, J.3
Sato, K.4
Fukata, M.5
Takefuji, M.6
Nakagawa, M.7
Izumi, N.8
Akiyama, T.9
Kaibuchi, K.10
-
106
-
-
22244478043
-
Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death
-
Weaver, B. A. and Cleveland, D. W. (2005). Decoding the links between mitosis, cancer, and chemotherapy: the mitotic checkpoint, adaptation, and cell death. Cancer Cell 8, 7-12.
-
(2005)
Cancer Cell
, vol.8
, pp. 7-12
-
-
Weaver, B.A.1
Cleveland, D.W.2
-
107
-
-
33846065784
-
Aneuploidy acts both oncogenically and as a tumor suppressor
-
Weaver, B. A., Silk, A. D., Montagna, C., Verdier-Pinard, P. and Cleveland, D. W. (2007). Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell 11, 25-36.
-
(2007)
Cancer Cell
, vol.11
, pp. 25-36
-
-
Weaver, B.A.1
Silk, A.D.2
Montagna, C.3
Verdier-Pinard, P.4
Cleveland, D.W.5
-
108
-
-
4444360489
-
EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration
-
Wen, Y., Eng, C. H., Schmoranzer, J., Cabrera-Pocb, N., Morris, K J., Chen, M., Wallar, B. J., Alberts, A. S. and Gundersen, G. G. (2004). EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration. Nat. Cell Biol. 6, 820-830.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 820-830
-
-
Wen, Y.1
Eng, C.H.2
Schmoranzer, J.3
Cabrera-Pocb, N.4
Morris, K.J.5
Chen, M.6
Wallar, B.J.7
Alberts, A.S.8
Gundersen, G.G.9
-
109
-
-
0029835278
-
Forced expression of the tumor suppressor adenomatosis polyposis coli protein induces disordered cell migration in the intestinal epithelium
-
Wong, M. H., Hermiston, M. L., Syder, A. J. and Gordon, J. I. (1996). Forced expression of the tumor suppressor adenomatosis polyposis coli protein induces disordered cell migration in the intestinal epithelium. Proc. Natl. Acad. Sci. USA 93, 9588-9593.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9588-9593
-
-
Wong, M.H.1
Hermiston, M.L.2
Syder, A.J.3
Gordon, J.I.4
|