Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block

Nature Immunology

Volumn 7, Issue 10, 2006, Pages 1048-1056

  Kirstetter, Peggy ^a   Anderson, Kristina ^b   Porse, Bo T ^c   Jacobsen, Sten Eirik W ^b   Nerlov, Claus ^a,b  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Italy)

^b LUND UNIVERSITY   (Sweden)

^c Copenhagen University Hospital ^*  (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; INTEGRIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BMI 1; TRANSCRIPTION FACTOR HOXB4; TRANSCRIPTION FACTOR PU 1; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINEAGE; CELL LOSS; CELL POPULATION; CONTROLLED STUDY; EMBRYO; ERYTHROCYTE; ERYTHROID CELL; GENE EXPRESSION; GENETIC CODE; GRANULOCYTE; HEMATOPOIETIC STEM CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BETA CATENIN; CELL DIFFERENTIATION; CELL LINEAGE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; INTEGRINS; MICE; MICE, MUTANT STRAINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; WNT PROTEINS;

EID: 33748850636     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1381     Document Type: Article

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