Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability

Journal of Cell Science

Volumn 117, Issue 26, 2004, Pages 6339-6353

  Tighe, Anthony ^a   Johnson, Victoria L ^a   Taylor, Stephen S ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Adenomatous polyposis coli; Bub1; BubR1; Centrosome; Genetic instability; Mitosis

Indexed keywords

APC PROTEIN;

ALLELE; AMINO TERMINAL SEQUENCE; ANEUPLOIDY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL DAMAGE; CELL PROLIFERATION; CELL STRAIN HCT116; CELL SURVIVAL; CHROMOSOMAL INSTABILITY; COLON CANCER; CONTROLLED STUDY; DICENTRIC CHROMOSOME; DIPLOIDY; FREQUENCY ANALYSIS; GENE LOSS; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; MITOSIS; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; WILD TYPE;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ALLELES; ANEUPLOIDY; BLOTTING, WESTERN; CELL PROLIFERATION; CELL SURVIVAL; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATIONS; CLONE CELLS; FLUORESCENT ANTIBODY TECHNIQUE; GENES, APC; HCT116 CELLS; HUMANS; KINETOCHORES; MICROTUBULES; MITOSIS; MITOTIC INDEX; MITOTIC SPINDLE APPARATUS; MUTATION;

EID: 13444261036     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01556     Document Type: Article

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