-
1
-
-
0037415605
-
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation
-
J.R. Babu, K.B. Jeganathan, D.J. Baker, X. Wu, N. Kang-Decker, and J.M. van Deursen Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation J. Cell Biol. 160 2003 341 353
-
(2003)
J. Cell Biol.
, vol.160
, pp. 341-353
-
-
Babu, J.R.1
Jeganathan, K.B.2
Baker, D.J.3
Wu, X.4
Kang-Decker, N.5
Van Deursen, J.M.6
-
2
-
-
3042761646
-
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
-
D.J. Baker, K.B. Jeganathan, J.D. Cameron, M. Thompson, S. Juneja, A. Kopecka, R. Kumar, R.B. Jenkins, P.C. de Groen, P. Roche, and J.M. van Deursen BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice Nat. Genet. 36 2004 744 749
-
(2004)
Nat. Genet.
, vol.36
, pp. 744-749
-
-
Baker, D.J.1
Jeganathan, K.B.2
Cameron, J.D.3
Thompson, M.4
Juneja, S.5
Kopecka, A.6
Kumar, R.7
Jenkins, R.B.8
De Groen, P.C.9
Roche, P.10
Van Deursen, J.M.11
-
3
-
-
0033549477
-
Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila
-
J. Basu, H. Bousbaa, E. Logarinho, Z. Li, B.C. Williams, C. Lopes, C.E. Sunkel, and M.L. Goldberg Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila J. Cell Biol. 146 1999 13 28
-
(1999)
J. Cell Biol.
, vol.146
, pp. 13-28
-
-
Basu, J.1
Bousbaa, H.2
Logarinho, E.3
Li, Z.4
Williams, B.C.5
Lopes, C.6
Sunkel, C.E.7
Goldberg, M.L.8
-
5
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
D.P. Cahill, C. Lengauer, J. Yu, G.J. Riggins, J.K. Willson, S.D. Markowitz, K.W. Kinzler, and B. Vogelstein Mutations of mitotic checkpoint genes in human cancers Nature 392 1998 300 303
-
(1998)
Nature
, vol.392
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
Riggins, G.J.4
Willson, J.K.5
Markowitz, S.D.6
Kinzler, K.W.7
Vogelstein, B.8
-
6
-
-
9144253124
-
Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency
-
W. Dai, Q. Wang, T. Liu, M. Swamy, Y. Fang, S. Xie, R. Mahmood, Y.M. Yang, M. Xu, and C.V. Rao Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency Cancer Res. 64 2004 440 445
-
(2004)
Cancer Res.
, vol.64
, pp. 440-445
-
-
Dai, W.1
Wang, Q.2
Liu, T.3
Swamy, M.4
Fang, Y.5
Xie, S.6
Mahmood, R.7
Yang, Y.M.8
Xu, M.9
Rao, C.V.10
-
7
-
-
0013057087
-
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
-
C. Ditchfield, V.L. Johnson, A. Tighe, R. Ellston, C. Haworth, T. Johnson, A. Mortlock, N. Keen, and S.S. Taylor Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores J. Cell Biol. 161 2003 267 280
-
(2003)
J. Cell Biol.
, vol.161
, pp. 267-280
-
-
Ditchfield, C.1
Johnson, V.L.2
Tighe, A.3
Ellston, R.4
Haworth, C.5
Johnson, T.6
Mortlock, A.7
Keen, N.8
Taylor, S.S.9
-
8
-
-
0034625268
-
Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2
-
M. Dobles, V. Liberal, M.L. Scott, R. Benezra, and P.K. Sorger Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 Cell 101 2000 635 645
-
(2000)
Cell
, vol.101
, pp. 635-645
-
-
Dobles, M.1
Liberal, V.2
Scott, M.L.3
Benezra, R.4
Sorger, P.K.5
-
9
-
-
0036199862
-
Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
-
G. Fang Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex Mol. Biol. Cell 13 2002 755 766
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 755-766
-
-
Fang, G.1
-
10
-
-
0032525783
-
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
-
G. Fang, H. Yu, and M.W. Kirschner The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation Genes Dev. 12 1998 1871 1883
-
(1998)
Genes Dev.
, vol.12
, pp. 1871-1883
-
-
Fang, G.1
Yu, H.2
Kirschner, M.W.3
-
11
-
-
0035070046
-
Mutations in the APC tumour suppressor gene cause chromosomal instability
-
R. Fodde, J. Kuipers, C. Rosenberg, R. Smits, M. Kielman, C. Gaspar, J.H. van Es, C. Breukel, J. Wiegant, R.H. Giles, and H. Clevers Mutations in the APC tumour suppressor gene cause chromosomal instability Nat. Cell Biol. 3 2001 433 438
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 433-438
-
-
Fodde, R.1
Kuipers, J.2
Rosenberg, C.3
Smits, R.4
Kielman, M.5
Gaspar, C.6
Van Es, J.H.7
Breukel, C.8
Wiegant, J.9
Giles, R.H.10
Clevers, H.11
-
12
-
-
0037011119
-
Identification of a MAD2-binding protein, CMT2, and its role in mitosis
-
T. Habu, S.H. Kim, J. Weinstein, and T. Matsumoto Identification of a MAD2-binding protein, CMT2, and its role in mitosis EMBO J. 21 2002 6419 6428
-
(2002)
EMBO J.
, vol.21
, pp. 6419-6428
-
-
Habu, T.1
Kim, S.H.2
Weinstein, J.3
Matsumoto, T.4
-
13
-
-
10644258336
-
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
-
S. Hanks, K. Coleman, S. Reid, A. Plaja, H. Firth, D. Fitzpatrick, A. Kidd, K. Mehes, R. Nash, and N. Robin Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B Nat. Genet. 36 2004 1159 1161
-
(2004)
Nat. Genet.
, vol.36
, pp. 1159-1161
-
-
Hanks, S.1
Coleman, K.2
Reid, S.3
Plaja, A.4
Firth, H.5
Fitzpatrick, D.6
Kidd, A.7
Mehes, K.8
Nash, R.9
Robin, N.10
-
14
-
-
0038746733
-
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint
-
S. Hauf, R.W. Cole, S. LaTerra, C. Zimmer, G. Schnapp, R. Walter, A. Heckel, J. van Meel, C.L. Rieder, and J.M. Peters The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint J. Cell Biol. 161 2003 281 294
-
(2003)
J. Cell Biol.
, vol.161
, pp. 281-294
-
-
Hauf, S.1
Cole, R.W.2
Laterra, S.3
Zimmer, C.4
Schnapp, G.5
Walter, R.6
Heckel, A.7
Van Meel, J.8
Rieder, C.L.9
Peters, J.M.10
-
15
-
-
0025941405
-
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
-
M.A. Hoyt, L. Totis, and B.T. Roberts S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function Cell 66 1991 507 517
-
(1991)
Cell
, vol.66
, pp. 507-517
-
-
Hoyt, M.A.1
Totis, L.2
Roberts, B.T.3
-
16
-
-
2342439525
-
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
-
V.L. Johnson, M.I. Scott, S.V. Holt, D. Hussein, and S.S. Taylor Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression J. Cell Sci. 117 2004 1577 1589
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1577-1589
-
-
Johnson, V.L.1
Scott, M.I.2
Holt, S.V.3
Hussein, D.4
Taylor, S.S.5
-
17
-
-
0034665634
-
Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis
-
P. Kalitsis, E. Earle, K.J. Fowler, and K.H. Choo Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis Genes Dev. 14 2000 2277 2282
-
(2000)
Genes Dev.
, vol.14
, pp. 2277-2282
-
-
Kalitsis, P.1
Earle, E.2
Fowler, K.J.3
Choo, K.H.4
-
18
-
-
0035067391
-
A role for the Adenomatous Polyposis Coli protein in chromosome segregation
-
K.B. Kaplan, A.A. Burds, J.R. Swedlow, S.S. Bekir, P.K. Sorger, and I.S. Nathke A role for the Adenomatous Polyposis Coli protein in chromosome segregation Nat. Cell Biol. 3 2001 429 432
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 429-432
-
-
Kaplan, K.B.1
Burds, A.A.2
Swedlow, J.R.3
Bekir, S.S.4
Sorger, P.K.5
Nathke, I.S.6
-
19
-
-
0034605123
-
Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5
-
T.M. Kapoor, T.U. Mayer, M.L. Coughlin, and T.J. Mitchison Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5 J. Cell Biol. 150 2000 975 988
-
(2000)
J. Cell Biol.
, vol.150
, pp. 975-988
-
-
Kapoor, T.M.1
Mayer, T.U.2
Coughlin, M.L.3
Mitchison, T.J.4
-
20
-
-
2942567685
-
Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint
-
G.J. Kops, D.R. Foltz, and D.W. Cleveland Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint Proc. Natl. Acad. Sci. USA 101 2004 8699 8704
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8699-8704
-
-
Kops, G.J.1
Foltz, D.R.2
Cleveland, D.W.3
-
21
-
-
0026009964
-
Feedback control of mitosis in budding yeast
-
R. Li, and A.W. Murray Feedback control of mitosis in budding yeast Cell 66 1991 519 531
-
(1991)
Cell
, vol.66
, pp. 519-531
-
-
Li, R.1
Murray, A.W.2
-
22
-
-
0037385783
-
Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis
-
S.T. Liu, J.C. Hittle, S.A. Jablonski, M.S. Campbell, K. Yoda, and T.J. Yen Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis Nat. Cell Biol. 5 2003 341 345
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 341-345
-
-
Liu, S.T.1
Hittle, J.C.2
Jablonski, S.A.3
Campbell, M.S.4
Yoda, K.5
Yen, T.J.6
-
23
-
-
0038446875
-
Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1
-
Y. Mao, A. Abrieu, and D.W. Cleveland Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1 Cell 114 2003 87 98
-
(2003)
Cell
, vol.114
, pp. 87-98
-
-
Mao, Y.1
Abrieu, A.2
Cleveland, D.W.3
-
24
-
-
4344610852
-
Timing and checkpoints in the regulation of mitotic progression
-
P. Meraldi, V.M. Draviam, and P.K. Sorger Timing and checkpoints in the regulation of mitotic progression Dev. Cell 7 2004 45 60
-
(2004)
Dev. Cell
, vol.7
, pp. 45-60
-
-
Meraldi, P.1
Draviam, V.M.2
Sorger, P.K.3
-
25
-
-
0035905811
-
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
-
L.S. Michel, V. Liberal, A. Chatterjee, R. Kirchwegger, B. Pasche, W. Gerald, M. Dobles, P.K. Sorger, V.V. Murty, and R. Benezra MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells Nature 409 2001 355 359
-
(2001)
Nature
, vol.409
, pp. 355-359
-
-
Michel, L.S.1
Liberal, V.2
Chatterjee, A.3
Kirchwegger, R.4
Pasche, B.5
Gerald, W.6
Dobles, M.7
Sorger, P.K.8
Murty, V.V.9
Benezra, R.10
-
26
-
-
1842533070
-
Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells
-
L. Michel, E. Diaz-Rodriguez, G. Narayan, E. Hernando, V.V. Murty, and R. Benezra Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells Proc. Natl. Acad. Sci. USA 101 2004 4459 4464
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4459-4464
-
-
Michel, L.1
Diaz-Rodriguez, E.2
Narayan, G.3
Hernando, E.4
Murty, V.V.5
Benezra, R.6
-
27
-
-
0036744787
-
Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E
-
F.R. Putkey, T. Cramer, M.K. Morphew, A.D. Silk, R.S. Johnson, J.R. McIntosh, and D.W. Cleveland Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E Dev. Cell 3 2002 351 365
-
(2002)
Dev. Cell
, vol.3
, pp. 351-365
-
-
Putkey, F.R.1
Cramer, T.2
Morphew, M.K.3
Silk, A.D.4
Johnson, R.S.5
McIntosh, J.R.6
Cleveland, D.W.7
-
28
-
-
15444370589
-
Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability
-
C.V. Rao, Y.M. Yang, M.V. Swamy, T. Liu, Y. Fang, R. Mahmood, M. Jhanwar-Uniyal, and W. Dai Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability Proc. Natl. Acad. Sci. USA 102 2005 4365 4370
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4365-4370
-
-
Rao, C.V.1
Yang, Y.M.2
Swamy, M.V.3
Liu, T.4
Fang, Y.5
Mahmood, R.6
Jhanwar-Uniyal, M.7
Dai, W.8
-
29
-
-
7744233719
-
Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint
-
C.L. Rieder, and H. Maiato Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint Dev. Cell 7 2004 637 651
-
(2004)
Dev. Cell
, vol.7
, pp. 637-651
-
-
Rieder, C.L.1
Maiato, H.2
-
30
-
-
2342563857
-
Antitumor activity of a kinesin inhibitor
-
R. Sakowicz, J.T. Finer, C. Beraud, A. Crompton, E. Lewis, A. Fritsch, Y. Lee, J. Mak, R. Moody, and R. Turincio Antitumor activity of a kinesin inhibitor Cancer Res. 64 2004 3276 3280
-
(2004)
Cancer Res.
, vol.64
, pp. 3276-3280
-
-
Sakowicz, R.1
Finer, J.T.2
Beraud, C.3
Crompton, A.4
Lewis, E.5
Fritsch, A.6
Lee, Y.7
Mak, J.8
Moody, R.9
Turincio, R.10
-
31
-
-
0035802122
-
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
-
V. Sudakin, G.K. Chan, and T.J. Yen Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 J. Cell Biol. 154 2001 925 936
-
(2001)
J. Cell Biol.
, vol.154
, pp. 925-936
-
-
Sudakin, V.1
Chan, G.K.2
Yen, T.J.3
-
32
-
-
0035435063
-
Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1
-
Z. Tang, R. Bharadwaj, B. Li, and H. Yu Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1 Dev. Cell 1 2001 227 237
-
(2001)
Dev. Cell
, vol.1
, pp. 227-237
-
-
Tang, Z.1
Bharadwaj, R.2
Li, B.3
Yu, H.4
-
33
-
-
22244459880
-
Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage
-
W. Tao, V.J. South, Y. Zhang, J.P. Davide, L. Farrell, N.E. Kohl, L. Sepp-Lorenzino, and R.B. Lobell Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage this issue Cancer Cell 2005 000 000
-
(2005)
Cancer Cell
, pp. 000-000
-
-
Tao, W.1
South, V.J.2
Zhang, Y.3
Davide, J.P.4
Farrell, L.5
Kohl, N.E.6
Sepp-Lorenzino, L.7
Lobell, R.B.8
-
34
-
-
0034906435
-
Aneuploid colon cancer cells have a robust spindle checkpoint
-
A. Tighe, V.L. Johnson, M. Albertella, and S.S. Taylor Aneuploid colon cancer cells have a robust spindle checkpoint EMBO Rep. 2 2001 609 614
-
(2001)
EMBO Rep.
, vol.2
, pp. 609-614
-
-
Tighe, A.1
Johnson, V.L.2
Albertella, M.3
Taylor, S.S.4
-
35
-
-
10744222603
-
BUBR1 deficiency results in abnormal megakaryopoiesis
-
Q. Wang, T. Liu, Y. Fang, S. Xie, X. Huang, R. Mahmood, G. Ramaswamy, K.M. Sakamoto, Z. Darzynkiewicz, M. Xu, and W. Dai BUBR1 deficiency results in abnormal megakaryopoiesis Blood 103 2004 1278 1285
-
(2004)
Blood
, vol.103
, pp. 1278-1285
-
-
Wang, Q.1
Liu, T.2
Fang, Y.3
Xie, S.4
Huang, X.5
Mahmood, R.6
Ramaswamy, G.7
Sakamoto, K.M.8
Darzynkiewicz, Z.9
Xu, M.10
Dai, W.11
-
36
-
-
0034518709
-
Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells
-
X. Wang, D.Y. Jin, Y.C. Wong, A.L. Cheung, A.C. Chun, A.K. Lo, Y. Liu, and S.W. Tsao Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells Carcinogenesis 21 2000 2293 2297
-
(2000)
Carcinogenesis
, vol.21
, pp. 2293-2297
-
-
Wang, X.1
Jin, D.Y.2
Wong, Y.C.3
Cheung, A.L.4
Chun, A.C.5
Lo, A.K.6
Liu, Y.7
Tsao, S.W.8
-
37
-
-
12444311754
-
Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells
-
R. Wasch, and D. Engelbert Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells Oncogene 24 2005 1 10
-
(2005)
Oncogene
, vol.24
, pp. 1-10
-
-
Wasch, R.1
Engelbert, D.2
-
38
-
-
0042978646
-
Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
-
B.A. Weaver, Z.Q. Bonday, F.R. Putkey, G.J. Kops, A.D. Silk, and D.W. Cleveland Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss J. Cell Biol. 162 2003 551 563
-
(2003)
J. Cell Biol.
, vol.162
, pp. 551-563
-
-
Weaver, B.A.1
Bonday, Z.Q.2
Putkey, F.R.3
Kops, G.J.4
Silk, A.D.5
Cleveland, D.W.6
|