Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human

American Journal of Pathology

Volumn 170, Issue 1, 2007, Pages 377-387

  Alberici, Paola ^a   De Pater, Emma ^a   Cardoso, Joana ^a   Bevelander, Mieke ^a   Molenaar, Lia ^a   Jonkers, Jos ^b   Fodde, Riccardo ^a  

^a JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; K RAS PROTEIN; PROTEIN P53; ONCOPROTEIN;

ALLELE; ANEUPLOIDY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER STAGING; CARCINOGENESIS; CHROMOSOMAL INSTABILITY; CHROMOSOME; CHROMOSOME 12Q; CHROMOSOME 1P; CHROMOSOME 22Q; CHROMOSOME 9Q; CHROMOSOME ABERRATION; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; GENE ACTIVATION; GENE LOCUS; GENE LOSS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; INTESTINE CANCER; INTESTINE TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR SUPPRESSOR GENE; VALIDATION STUDY; ANIMAL; COMPARATIVE STUDY; GENETICS; HUMAN CHROMOSOME; MUTATION; NUCLEIC ACID HYBRIDIZATION; SPECIES DIFFERENCE;

ANEUPLOIDY; ANIMALS; CHROMOSOMAL INSTABILITY; CHROMOSOMES, HUMAN; GENES, APC; GENES, P53; HUMANS; INTESTINAL NEOPLASMS; MICE; MUTATION; NUCLEIC ACID HYBRIDIZATION; PROTO-ONCOGENE PROTEINS; SPECIES SPECIFICITY;

EID: 33847024023     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2007.060853     Document Type: Article

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