Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

Development

Volumn 128, Issue 8, 2001, Pages 1253-1264

  Brault, V ^a   Moore, R ^a   Kutsch, S ^a   Ishibashi, M ^a   Rowitch, D H ^a   McMahon, A P ^a   Sommer, L ^a   Boussadia, O ^a   Kemler, R ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

catenin; Cell adhesion; CNS development; Conditional inactivation; Mouse; Neural crest; Wnt1

Indexed keywords

BETA CATENIN; CADHERIN; CATENIN; CELL ADHESION MOLECULE; CRE RECOMBINASE; LOXP PROTEIN; PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT1 PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; BRAIN DEVELOPMENT; BRAIN MALFORMATION; CELL DIFFERENTIATION; CELL FATE; CELL MIGRATION; CELL SURVIVAL; CEREBELLUM; CHONDROGENESIS; CONTROLLED STUDY; CRANIOFACIAL DEVELOPMENT; EMBRYO; EXON; GANGLION; GENE CONTROL; GENE DELETION; GENE FUNCTION; GENE INACTIVATION; GENE SEQUENCE; GENETIC RECOMBINATION; KNOCKOUT GENE; MESENCEPHALON; MORPHOGENESIS; MOUSE; NEURAL CREST CELL; NEURAL TUBE; NONHUMAN; PHENOTYPE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATOR GENE; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; BETA CATENIN; BIOLOGICAL MARKERS; BRAIN; BRANCHIAL REGION; CELLS, CULTURED; CRANIOFACIAL ABNORMALITIES; CYTOSKELETAL PROTEINS; FEMALE; GANGLIA, SPINAL; INTEGRASES; MALE; MESENCEPHALON; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENESIS; NEURAL CREST; PROTO-ONCOGENE PROTEINS; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; SKULL; TRANS-ACTIVATORS; VIRAL PROTEINS; WNT PROTEINS; WNT1 PROTEIN; ZEBRAFISH PROTEINS;

ANIMALIA; MUS MUSCULUS;

EID: 0035034603     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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