On the origin of biochemistry at an alkaline hydrothermal vent

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 362, Issue 1486, 2007, Pages 1887-1926

  Martin, William ^a   Russell, Michael J ^b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Acetyl phosphate; Carbamoyl phosphate; Carboxyphosphate; Formyl phosphate; Origin of life; Thioesters

Indexed keywords

AMMONIA; CARBON DIOXIDE; CARBON FIXATION; CITRIC ACID; ESTER; HYDROTHERMAL VENT; ORIGIN OF LIFE; PHOSPHATE;

ARCHAEA; BACTERIA (MICROORGANISMS); HARNESS;

EID: 35148861695     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.2006.1881     Document Type: Review

References (229)

1. Ahmed, H., Ettema, T. J., Tjaden, B., Geerling, A. C., van der Oost, J. & Siebers, B. 2005 The semi-phosphorylative Entner-Doudoroff pathway in hyperthermophilic archaea: a re-evaluation. Biochem. J. 390, 529-540. (doi:10.1042/BJ20041711)
2. Amend, J. P. & Shock, E. L. 2001 Energetics of overall metabolic reactions of thermophilic and hyperthermophilic Archaea and Bacteria. FEMS Microbiol. Rev. 25, 175-243. (doi:10.1111/j.1574-6976.2001.tb00576.x)
3. 6-type compounds. Orig. Life Evol. Biosph. 29, 287-296. (doi:10.1023/A:1006532518221)
4. Bach, W., Paulick, H., Garrido C. J. Ildefonse, B., Meurer, W. P. & Humphris, S. E. 2006 Unraveling the sequence of serpentinization reactions: petrography, mineral chemistry, and petrophysics of serpentinites from MAR 15° N (ODP Leg 209, Site 1274). Geophys. Res. Lett. 33, L13306.
5. Bada, J. L. & Lazcano, A. 2002 Some like it hot, but not the first biomolecules. Science 296, 1982-1983. (doi:10.1126/science. 1069487)
6. +-PPases: a tightly membrane-bound family. FEBS Lett. 457, 527-533. (doi:10.1016/S0014-5793(99)90617-8)
7. Baross, J. A. & Hoffman, S. E. 1985 Submarine hydrothermal vents and associated gradient environments as sites for the origin and evolution of life. Orig. Life Evol. Biosph. 15, 327-345. (doi:10.1007/BF01808177)
8. 2 in methanogenic archaea. Thermodynamics and kinetics of the spontaneous reaction. Eur. J. Biochem. 267, 3130-3138. (doi:10.1046/j.1432-1327.2000.01331.x)
9. Baymann, F., Lebrun, E., Brugna, M., Schoepp-Cothenet, B., Guidici-Oritconi, M.-T. & Nitschke, W. 2003 The redox protein construction kit: pre-last universal common ancestor evolution of energy-conserving enzymes. Phil. Trans. R. Soc. B 358, 267-274. (doi:10.1098/rstb.2002.1184)
10. Begley, T. P. et al. 1999 Thiamin biosynthesis in prokaryotes. Arch. Microbiol. 171, 293-300. (doi:10.1007/s002030050713)
11. Berry, S. 2002 The chemical basis of membrane bioenergetics. J. Mol. Evol. 54, 595-613. (doi:10.1007/s00239-001-0056-3)
12. Bock, A. K. & Schönheit, P. 1995 Growth of Methanosarcina barkeri (Fusaro) under nonmethanogenic conditions by the fermentation of pyruvate to acetate: ATP synthesis via the mechanism of substrate level phosphorylation. J. Bacteriol. 177, 2002-2007.
13. 4 cluster. Science 275, 1305-1308. (doi:10.1126/science.275.5304. 1305)
14. Brondino, C. D., Passeggi, M. C., Caldeira, J., Almendra, M. J., Feio, M. J., Moura, J. J. & Moura, I. 2004 Incorporation of either molybdenum or tungsten into formate dehydrogenase from Desulfovibrio alaskensis NCIMB 13491; EPR assignment of the proximal iron-sulfur cluster to the pterin cofactor in formate dehydrogenases from sulfate-reducing bacteria. J. Biol. Inorg. Chem. 9, 145-151. (doi:10.1007/s00775-003-0506-z)
15. Buckel, W. & Eggerer, H. 1965 On the optical determination of citrate synthase and acetyl-coenzyme A. Biochem. Z. 343, 29-43.
16. Buttlaire, H., Himes, R. H. & Reed, G. H. 1976 Formyltetrahydrofolate synthetase-catalyzed formation of ATP from carbamyl phosphate and ADP. J. Biol. Chem. 251, 4159-4161.
17. Cavalier-Smith, T. 2002 The neomuran origin of archae-bacteria, the negibacterial root of the universal tree and bacterial megaclassification. Int. J. Syst. Evol. Microbiol. 52, 7-76.
18. Cerff, R. 1982 Separation and purification of NAD- and NADP-linked glyceraldehyde-3-phosphate dehydrogenases from higher plants. In Methods in chloroplast molecular biology (eds M. Edelmann, R. B. Hallick & N.-H. Chua), pp. 683-694. Amsterdam, The Netherlands: Elsevier Biomedical Press.
19. Chistoserdova, L., Jenkins, C., Kalyuzhnaya, M. G., Marx, C. J., Lapidus, A., Vorholt, J. A., Staley, J. T. & Lidstrom, M. E. 2004 The enigmatic Planctomycetes may hold a key to the origins of methanogenesis and methylotrophy. Mol. Biol. Evol. 21, 1234-1241. (doi:10.1093/molbev/msh113)
20. Cody, G. D. 2004 Transition metal sulfides and the origin of metabolism. Annu. Rev. Earth Planet. Sci. 32, 569-599. (doi:10.1146/annurev. earth.32.101802.120225)
21. Cody, G. D., Boctor, N. Z., Filley, T. R., Hazen, R. M., Scott, J. H., Sharma, A. & Yoder Jr, H. S. 2000 Primordial carbonylated iron-sulfur compounds and the synthesis of pyruvate. Science 289, 1337-1340. (doi:10.1126/science.289.5483.1337)
22. Cook, A. G. & Knowles, J. R. 1985 Phosphoenolpyruvate synthetase and pyruvate, orthophosphate dikinase: stereochemical consequences at both the β-phospho and γ-phospho groups of ATP. Biochemistry 24, 51-58. (doi:10.1021/bi00322a009)
23. Cooper, R. A. & Kornberg, H. L. 1967 The direct synthesis of phosphoenolpyruvate from pyruvate by Escherichia coli. Proc. R. Soc. B 168, 263-280.
24. 2O, and NO). Microbiol. Rev. 60, 609-640.
25. Copley, S. D., Smith, E. & Morowitz, H. J. 2005 A mechanism for the association of amino acids with their codons and the origin of the genetic code. Proc. Natl Acad. Sci. USA 102, 4442-4447. (doi:10.1073/pnas. 0501049102)
26. Corliss, J. B., Baross, J. A. & Hoffmann, S. E. 1981 An hypothesis concerning the relationship between submarine hot springs and the origin of life on Earth. Oceanol. Acta 4, 59-69. (Suppl.)
27. Daniels, L. 1993 The biochemistry of methanogens. In The biochemistry of achaea (eds M. Kates, D. Kushner & A. T. Matheson), pp. 41-112. Amsterdam, The Netherlands: Elsevier.
28. 4] clusters in closed and open α subunits of acetyl-CoA synthase/carbon monoxide dehydrogenase. Nat. Struct. Biol. 10, 271-279. (doi:10.1038/nsb912)
29. 2-reductases) involved in syntrophic propionate oxidation by Syntrophobacter fumaroxidans. Eur. J. Biochem. 270, 2476-2485. (doi:10.1046/j.1432-1033.2003.03619.x)
30. de Duve, C. 1988 Prebiotic syntheses and the mechanism of early chemical evolution. In The roots of modern biochemistry (eds H. Kleinkauf, H. von Döhzen & L. Jaenicke), pp. 881-894. Berlin, Germany: de Gruyter.
31. de Duve, C. 1991 Blueprint for a cell: the nature and origin of life, p. 275. Burlington, NC: Neil Patterson.
32. de Duve, C. 2003 A research proposal on the origin of life. Orig. Life Evol. Biosph. 33, 559-574. (doi:10.1023/A:1025760311436)
33. de Poorter, L. M. I., Geerts, W. G., Theuvenet, A. P. R. & Keltjens, J. T. 2003 Bioenergetics of the formyl-methanofuran dehydrogenase and heterodisulfide reductase reactions in Methanothermobacter thermautotrophicus. Eur. J. Biochem. 270, 66-75. (doi:10.1046/j.1432- 1033.2003.03362.x)
34. de Zwart, I. I., Meade, S. J. & Pratt, A. J. 2004 Biomimetic phosphoryl transfer catalysed by iron(II)-mineral precipitates. Geochim. Cosmochim. Acta 68, 4093-4098. (doi:10.1016/j.gca.2004.01.028)
35. Doolittle, W. F. 1999 Phylogenetic classification and the universal tree. Scicnce 284, 2124-2128. (doi:10.1126/science.284.5423.2124)
36. Doukov, T. I., Iverson, T. M., Seravalli, J., Ragsdale, S. W. & Drennan, C. L. 2002 A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase. Science 298, 567-572. (doi:10.1126/science.1075843)
37. 6 and structurally related derivatives. FEBS Lett. 390, 179-182. (doi:10.1016/0014-5793(96)00652-7)
38. 6 biosynthesis. FEBS Lett. 390, 179-182. (doi:10.1016/0014-5793(96)00652-7)
39. Durbecq, V., Legrain, C., Roovers, M., Piérard, A. & Glansdorff, N. 1997 The carbamate kinase-like carbamoyl phosphate synthetase of the hyperthermophilic archaeon Pyrococcus furiosus, a missing link in the evolution of carbamoyl phosphate biosynthesis. Proc. Natl Acad. Sci. USA 94, 12 803-12 808.
40. Eigen, M. 1992 Steps towards life. Oxford, UK: Oxford University Press.
41. Embley, T. M. & Martin, W. 2006 Eukaryote evolution, changes and challenges. Nature 440, 623-630. (doi:10.1038/nature04546)
42. Ensign, S. A. 1995 Reactivity of carbon monoxide dehydrogenase from Rhodospirillum rubrum with carbon dioxide, carbonyl sulfide, and carbon disulfide. Biochemistry. 34, 5372-5378. (doi:10.1021/bi00016a008)
43. Ermler, U., Grabarse, W., Shima, S., Goubeaud, M. & Thauer, R. K. 1997 Crystal structure of methyl coenzyme M reductase: the key enzyme of biological methane formation. Science 278, 1457-1462. (doi:10.1126/science.278.5342.1457)
44. Eschenmoser, A. 2004 The TNA-family of nucleic acid systems: properties and prospects. Orig. Life Evol. Biosph. 34, 277-306. (doi:10.1023/B:ORIG.0000016450.59665.f4)
45. Eubanks, L. M. & Poulter, C. D. 2003 Rhodobacter capsulatus 1-deoxy-D-xylulose 5-phosphate synthase: steady-state kinetics and substrate binding. Biochemistry 42, 1140-1149. (doi:10.1021/bi0205303)
46. Eyzaguirre, J., Jansen, K. & Fuchs, G. 1982 Phosphoenolpyruvate synthetase in Methanobacterium thermoautotrophicum. Arch. Microbiol. 132, 67-74. (doi:10.1007/BF00690820)
47. Fenchel, T. & Finlay, B. J. 1995 Ecology and evolution in anoxic worlds. Oxford, UK: Oxford University Press.
48. Ferry, J. G. & House, C. H. 2006 The step-wise evolution of early life driven by energy conservation. Mol. Biol. Evol. 23, 1286-1292. (doi:10.1093/molbev/msk014)
49. Fisher, A. T. 2005 Marine hydrogeology: recent accomplishments and future opportunities. Hydrogeol. J. 13, 69-97. (doi:10.1007/s10040-004- 0400-y)
50. Frey, P. A. & Arabshahi, A. 1995 Standard free energy change for the hydrolysis of the alpha, beta-phosphoanhydride bridge in ATP. Biochemistry 34, 11 307-11 310. (doi:10.1021/bi00036a001)
51. Früh-Green, G. L., Kelley, D. D., Bernascono, S. M. et al. 2003 30 000 years of hydrothermal activity at the Lost City vent field. Science 301, 495-498. (doi:10.1126/science.1085582)
52. 2 fixation in acetogenic bacteria: variations on a theme. FEMS Microbiol. Rev. 39, 181-213. (doi:10.1111/j.1574-6968.1986.tb01859.x)
53. 2 fixation. In Autotrophic bacteria (eds H. G. Schlegel & B. Bowien), pp. 365-382. Madison, WI: Science Tech Publishers.
54. Fuchs, G. 1994 Variations of the acetyl-CoA pathway in diversely related microorganisms that are not acetogens. In Acetogenesis (ed. G. Drake), pp. 506-538. New York, NY: Chapman and Hall.
55. 2 fixation. In Evolution of prokaryotes (eds K. H. Schleifer & E. Stackebrandt) FEMS Symposium No. 29, pp. 235-251. London, UK: Academic Press.
56. Furdui, C. & Ragsdale, S. W. 2000 The role of pyruvate ferredoxin oxidoreductase in pyruvate synthesis during autotrophic growth by the Wood-Ljungdahl pathway. J. Biol. Chem. 275, 28 494-28 499. (doi:10.1074/jbc.M003291200)
57. Gattinger, A., Schloter, M. & Munch, J. C. 2002 Phospholipid etherlipid and phospholipid fatty acid fingerprints in selected euryarchaeotal monocultures for taxonomic profiling. FEMS Microbiol. Lett. 213, 133-139.
58. Genschel, U. 2004 Coenzyme A biosynthesis: reconstruction of the pathway in archaea and an evolutionary scenario based on comparative genomics. Mol. Biol. Evol. 21, 1242-1251. (doi:10.1093/molbev/msh119)
59. Joyce, G. F. 2002 The antiquity of RNA-based evolution. Nature 418, 214-221. (doi:10.1038/418214a)
60. Gilbert, W. 1986 The RNA world. Nature 319, 618. (doi:10.1038/319618a0)
61. Goldschmidt, V. M. 1952 Geochemical aspects of the origin of complex organic molecules on Earth, as precursors to organic life. New Biol. 12, 97-105.
62. Grabowski, R., Hofmeister, A. E. & Buckel, W. 1993 Bacterial L-serine dehydratases: a new family of enzymes containing iron-sulfur clusters. Trends Biochem. Sci. 18, 297-300. (doi:10.1016/0968- 0004(93)90040-T)
63. Graham, D. E. & White, R. H. 2002 Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics. Nat. Prod. Rep. 19, 133-147. (doi:10.1039/b103714p)
64. Green, S. M., Malik, T., Giles, I. G. & Drabble, W. T. 1996 The purB gene of Escherichia coli K-12 is located in an operon. Microbiology 142, 3219-3230.
65. Guy, H. I., Bouvier, A. & Evans, D. R. 1997 The smallest carbamoyl-phosphate synthetase: a single catalytic subdomain catalyzes all three partial reactions. J. Biol. Chem. 272, 29 255-29 262. (doi:10.1074/jbc.272.46.29255)
66. Haldane, J. B. S. 1929 The orgin of life. The rationalist annu. 3, 3-10.
67. Hartman, H. 1975 Speculations on the origin and evolution of metabolism. J. Mol. Evol. 4, 359-370. (doi:10.1007/BF01732537)
68. Hedderich, R. 2004 Energy-converting [NiFe] hydrogenases from Archaea and extremophiles: ancestors of complex I. J. Bioenerg. Biomembr. 36, 65-75. (doi:10.1023/B:JOBB.0000019599.43969.33)
69. Heinen, W. & Lauwers, A. M. 1996 Organic sulfur compounds resulting from the interaction of iron sulfide, hydrogen sulfide and carbon dioxide in an anaerobic aqueous environment. Orig. Life Evol. Biosph. 26, 131-150. (doi:10.1007/BF01809852)
70. Hennet, R. J. C., Holm, N. G. & Engel, M. H. 1992 Abiotic synthesis of amino-acids under hydrothermal conditions and the origin of life - a perpetual phenomenon. Naturwissenschaften 79, 361-365. (doi:10.1007/BF01140180)
71. Hille, R. 2002 Molybdenum and tungsten in biology. Trends Biochem. Sci. 27, 360-367. (doi:10.1016/S0968-0004(02)02107-2)
72. Hochheimer, A., Schmitz, R. A., Thauer, R. K. & Hedderich, R. 1995 The tungsten formylmethanofuran dehydrogenase from Methanobacterium thermoautotrophicum contains sequence motifs characteristic for enzymes containing molybdopterin dinucleotide. Eur. J. Biochem. 234, 910-920. (doi:10.1111/j.1432-1033.1995.910_a.x)
73. Hochheimer, A., Hedderich, R. & Thauer, R. K. 1998 The formylmethanofuran dehydrogenase isoenzymes in Methanobacterium wolfei and Methanobacterium thermoautotrophicum: induction of the molybdenum isoenzyme by molybdate and constitutive synthesis of the tungsten isoenzyme. Arch. Microbiol. 170, 389-393. (doi:10.1007/s002030050658)
74. Hordijk, W. & Steel, M. 2004 Detecting autocatalytic, self-sustaining sets in chemical reaction systems. J. Theor. Biol. 227, 451-161. (doi:10.1016/j.jtbi.2003.11.020)
75. Horowitz, N. H. 1945 On the evolution of biochemical syntheses. Proc. Natl Acad. Sci. USA 31, 153-157. (doi:10.1073/pnas.31.6.153)
76. Huber, C. & Wächtershäuser, G. 1997 Activated acetic acid by carbon fixation on (Fe,Ni)S under primordial conditions. Science 276, 245-247. (doi:10.1126/science.276.5310.245)
77. Huber, C. & Wächtershäuser, G. 1998 Peptides by activation of amino acids with CO on Ni,Fe surfaces: implications for the origin of life. Science 281, 670-672. (doi:10.1126/science.281.5377.670)
78. Huber, C. & Wächtershäuser, G. 2003 Primordial reductive amination revisited. Tetrahedron Lett. 44, 1695-1697. (doi:10.1016/S0040-4039(02)02863-0)
79. 2 fixation pathways in Archaea (Crenarchaeota). Arch. Microbiol. 179, 160-173.
80. Hutchins, A. M., Holden, J. F. & Adams, M. W. W. 2001 Phosphoenolpyruvate synthetase from the hyperthermophilic archaeon Pyrococcus furiosus. J. Bacteriol. 183, 709-715. (doi:10.1128/JB.183.2.709-715. 2001)
81. Jahansouz, H., Scherübel, D. M. & Himkes, R. M. 1990 Formylation of tetrahydrofolate by formyl phosphate. FEBS Lett. 262, 366-368. (doi:10.1016/0014-5793(90)80231-7)
82. Jordan, S. L., McDonald, I. R., Kraczkiewicz-Dowjat, A. J., Kelly, D. P., Rainey, F. A., Murrell, J. C. & Wood, A. P. 1997 Autotrophic growth on carbon disulfide is a property of novel strains of Paracoccus denitrificans. Arch. Microbiol. 168, 225-236. (doi:10.1007/s002030050492)
83. 2. Eur. J. Biochem. 184, 223-232. (doi:10.1111/j.1432-1033.1989.tb15010.x)
84. Kandler, O. & König, H. 1998 Cell wall polymers in Archaea (Archaebacteria). Cell. Mol. Life Sci. 54, 305-308. (doi:10.1007/s000180050156)
85. Kappock, T. J., Ealick, S. E. & Stubbe, J. 2000 Modular evolution of the purine biosynthetic pathway. Curr. Opin. Chem. Biol. 4, 567-572. (doi:10.1016/S1367-5931(00)00133-2)
86. Karrasch, M., Börner, G. & Thauer, R. K. 1990 The molybdenum cofactor of formylmethanofuran dehydrogenase from Methanosarcina barkeri is a molybdopterin guanine dinucleotide. FEBS Lett. 274, 48-52. (doi:10.1016/0014-5793(90)81326-J)
87. Kasting, J. F. & Brown, L. L. 1998 The early atmosphere as a source of biogenic compounds. In The molecular origins of life (ed. A. Brack), pp. 35-56. Cambridge, UK: Cambridge University Press.
88. Keller, M., Blöchl, E., Wachtershauser, G. & Stetter, K. O. 1994 Formation of amide bonds without a condensation agent and implications for origin of life. Nature 368, 836-838. (doi:10.1038/368836a0)
89. Kelly, D. P. 1999 Thermodynamic aspects of energy conservation by chemolithotrophic sulfur bacteria in relation to the sulfur oxidation pathways. Arch. Microbiol. 171, 219-229. (doi:10.1007/s002030050703)
90. Kelley, D. S. et al. 2001 An off-axis hydrothermal vent field near the Mid-Atlantic Ridge at 30° N. Nature 412, 145-149. (doi:10.1038/35084000)
91. Kelley, D. S. et al. 2005 A serpentinite-hosted ecosystem: the Lost City hydrothermal field. Science 307, 1428-1434. (doi:10.1126/science.1102556)
92. III-ion- catalyzed nonenzymatic transformation of ADP into ATP. J. Chem. Soc. Perkin Trans. 2, 329-331.
93. Kitani, A., Tsunetsugu, S., Suzuki, A., Ito, S. & Sasaki, K. 1995 Fe(III)-ion-catalyzed nonenzymatic transformation of adenosine-diphosphate into adenosine-triphosphate. 2. Evidence of catalytic nature of Fe ions. Bioelectrochem. Bioenerget. 36, 47-51. (doi:10.1016/0302-4598(94) 01751-L)
94. Koga, Y., Kyuragi, T., Nishihara, M. & Sone, N. 1998 Did archaeal and bacterial cells arise independently from noncellular precursors? A hypothesis stating that the advent of membrane phospholipid with enantiomeric glycerophosphate backbones caused the separation of the two lines of descent. J. Mol. Evol. 46, 54-63. (doi:10.1007/PL00006283)
95. Koonin, E. V. & Martin, W. 2005 On the origin of genomes and cells within inorganic compartments. Trends Genet. 21, 647-654. (doi:10.1016/j.tig.2005.09.006)
96. Krüger, M. et al. 2003 A conspicuous nickel protein in microbial mats that oxidize methane anaerobically. Nature 426, 878-881.
97. 6 biosynthesis: formation of pyridoxine 5′-phosphate from 4-(phosphohydroxy)-L-threonine and 1-deoxy-D-xylulose-5- phosphate by PdxA and PdxJ protein. FEBS Lett. 449, 45-48. (doi:10.1016/S0014-5793(99)00393-2)
98. Leduc, S. 1911 The mechanism of life. London, UK: Rebman.
99. Lehninger, A. L. 1975 Biochemistry, 2nd edn, p. 1104. New York NY: Worth.
100. Leipe, D. D., Aravind, L. & Koonin, E. V. 1999 Did DNA replication evolve twice independendy? Nucleic Acids Res. 27, 3389-3401.
101. Leman, L., Orgel, L. & Ghadiri, M. R. 2004 Carbonyl sulfide-mediated prebiotic formation of peptides. Science 306, 283-286. (doi:10.1126/science.1102722)
102. Lengeler, J. W., Drews, G. & Schlegel, H. G. 1999 The biology of prokaryotes, p. 955. Oxford, UK: Blackwell Science.
103. Lesher, C. M. & Stone, W. E. 1997 Exploration geochemistry of komatiites. In Trace element geochemistry of volcanic rocks: applications for massive sulphide exploration, vol. 12, (eds D. A. Wyman). Short course notes, pp. 153-204. Canada: Geological Society of Canada.
104. Limbach, P. A., Crain, P. F. & McCloskey, J. A. 1994 Summary: the modified nucleosides of RNA. Nucleic Acids Res. 22, 2183-2196.
105. Lindahl, P. A. 2002 The Ni-containing carbon monoxide dehydrogenase family: light at the end of the tunnel? Biochemistry 41, 2097-2105. (doi:10.1021/bi015932+)
106. Lipmann, F. 1941 Metabolic generation and utilization of phosphate bond energy. Adv. Enzymol. 1, 99-162.
107. Ljungdahl, L. G. 1994 The acetyl-CoA pathway and the chemiosmotic generation of ATP during acetogenesis. In Acetogenesis (eds H. L. Drake), pp. 63-87. New York, NY: Chapman and Hall.
108. Lolkema, J. S., Chaban, Y. & Boekema, E. J. 2003 Subunit composition, structure, and distribution of bacterial V-type ATPases. J. Bioenerg. Biomembr. 35, 323-335. (doi:10.1023/A:1025776831494)
109. Lukens, L. N. & Buchanan, J. M. 1959 Biosynthesis of the purines. XXIV. The enzymatic synthesis of 5-amino-1-ribosyl-4-imidazolecarboxylic acid 5′-phosphate from 5-amino-1-ribosylimidazole 5′-phosphate and carbon dioxide. J. Biol. Chem. 234, 1799-1805.
110. 2, OCS and CS: frontier molecular orbital considerations. Aquat. Geochem. 10, 81-97. (doi:10.1023/B:AQUA. 0000038957.18584.b0)
111. 2-forming methylenetetrahydromethanopterin dehydrogenase as revealed by infrared spectroscopy. J. Am. Chem. Soc. 126, 14 239-14 248. (doi:10.1021/ja046818s)
112. Macleod, G., McKeown, C., Hall, A. J. & Russell, M. J. 1994 Hydrothermal and oceanic pH conditions of possible relevance to the origin of life. Orig. Life Evol. Biosph. 24, 19-41. (doi:10.1007/BF01582037)
113. Maden, B. E. H. 2000 Tetrahydrofolate and tetrahydromethanopterin compared: functionally distinct carriers in C1 metabolism. Biochem. J. 350, 609-629. (doi:10.1042/0264-6021:3500609)
114. Marolewski, A. E., Mattia, K. M., Warren, M. S. & Benkovic, S. J. 1997 Formyl phosphate: a proposed intermediate in the reaction catalyzed by Escherichia coli PurT GAR transformylase. Biochemistry 36, 6709-6716. (doi:10.1021/bi962961p)
115. Marshall, W. L. 1994 Hydrothermal synthesis of amino acids. Geochim. Cosmochim. Acta 58, 2099-2106. (doi:10.1016/0016-7037(94)90288-7)
116. Martin, W. & Müller, M. 1998 The hydrogen hypothesis for the first eukaryote. Nature 392, 37-11. (doi:10.1038/32096)
117. Martin, W. & Russell, M. 2003 On the origins of cells: a hypothesis for the evolutionary transitions from abiotic geochemistry to chemoautotrophic prokaryotes, and from prokaryotes to nucleated cells. Phil. Trans. R. Soc. B 358, 59-85. (doi:10.1098/rstb.2002.1183)
118. McCollom, T. & Seewald, J. S. 2003 Experimental constraints on the hydrothermal reactivity of organic acids and acid anions: I. Formic acid and formate. Geochim. Cosmochim. Acta 67, 3625-3644. (doi:10.1016/S0016-7037(03)00136-4)
119. Meister, M., Saum, S., Alber, B. E. & Fuchs, G. 2005 L-malyl-coenzyme A/β-methylmalyl-coenzyme A lyase is involved in acetate assimilation of the isocitrate lyase-negative bacterium Rhodobacter capsulatus. J. Bacteriol. 187, 1415-1425. (doi:10.1128/JB.187.4.1415- 1425.2005)
120. 10-formyltetrahydrofolate synthetase: evidence for formyl phosphate as an intermediate in the reaction. Biochemistry 28, 5136-5145. (doi:10.1021/bi00438a034)
121. Menon, S. & Ragsdale, S. W. 2000 Unleashing hydrogenase activity in carbon monoxide dehydrogenase/acetyl-CoA synthase and pyruvate : ferredoxin oxidoreductase. Biochemistry 35, 15 814-15 821. (doi:10.1021/bi9615598)
122. Mereschkowsky, C. 1910 Theorie der zwei Plasmaarten als Grundlage der Symbiogenesis, einer neuen Lehre von der Entstehung der Organismen. Biol. Centralbl. 30, 278-288. 289-303, 321-347, & 353-367
123. 6. J. Am. Chem. Soc. 74, 979-983. (doi:10.1021/ja01124a033)
124. Metzler, D. E. & Snell, E. E. 1952b Deamination of serine. I. catalytic deamination of serine and cysteine by pyridoxal and metal salts. J. Biol. Chem. 198, 353-361.
125. Miyakawa, S., Yamanashi, H., Kobayashi, K., Cleaves, H. J. & Miller, S. L. 2002 Prebiotic synthesis from CO atmospheres: implications for the origins of life. Proc. Natl Acad. Sci. USA 99, 14 628-14 631. (doi:10.1073/pnas.192568299)
126. Montange, R. K. & Batey, R. T. 2006 Structure of the S-adenosylmethionine riboswitch regulatory mRNA element. Nature 441, 1172-1175. (doi:10.1038/nature04819)
127. Mossel, E. & Steel, M. 2005 Random biochemical networks and the probability of self-sustaining autocatalysis. J. Theor. Biol. 233, 327-336. (doi:10.1016/j.jtbi.2004.10.011)
128. Morowitz, H. J., Kostelnik, J. D., Yang, J. & Cody, G. D. 2000 The origin of intermediary metabolism. Proc. Natl Acad. Sci. USA 97, 7704-7708. (doi:10.1073/pnas.110153997)
129. Mukund, S. & Adams, M. W. 1995 Glyceraldehyde-3-phosphate ferredoxin oxidoreductase, a novel tungsten-containing enzyme with a potential glycolytic role in the hyperthermophilic archaeon Pyrococcus furiosus. J. Biol. Chem. 270, 8389-8392. (doi:10.1074/jbc.270.15.8389)
130. Müller, M. 1996 Energy metabolism of amitochondriate protists, an evolutionary puzzle. Christian Gottfried Ehrenberg-Festschrift anlä?lich der 14. In Wissenschaftlichen Jahrestagung der Deutschen Gesellschaft fur Protozoologie, 9.-11. Marz 1995, Delitzsch (Sachsen) (eds M. Schlegel & K. Hausmann), pp. 63-76. Leipzig, Germany: Leipziger Universitätsverlag.
131. Müller, V. 2003 Energy conservation in acetogenic bacteria. Appl. Environ. Microbiol. 2003, 6345-6353. (doi:10.1128/AEM.69.11.6345- 6353.2003)
132. Nakada, H. I. & Weinhouse, S. 1953 Non-enzymatic transamination with glyoxylic acid and various amino acids. J. Biol. Chem. 204, 831-836.
133. Nekrasov, I. Y. A. & Konyushok, A. A. 1982 The physicochemical conditions of tungstenite formation. Mineralogicheskii Zhurnal 4, 33-40. [In Russian.]
134. Noltmann, E. A. 1972 Aldose-ketose isomerases. In The enzymes (ed. P. D. Boyer), pp. 271-354. New York, NY: Academic Press.
135. Norager, S., Arent, S., Bjornberg, O., Ottosen, M., Lo Leggio, L., Jensen, K. F. & Larsen, S. 2003 Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function. J. Biol. Chem. 278, 28 812-28 822. (doi:10.1074/jbc.M303767200)
136. O'Brien, R. W., Chuang, D. T., Taylor, B. L. & Utter, M. F. 1977 Novel enzymic machinery for the metabolism of oxalacetate, phosphoenolpyruvate, and pyruvate in Pseudomonas citronellolis. J. Biol. Chem. 252, 1257-1263.
137. Osborn, H. F. 1917 The origin and evolution of life on earth: on the theory of action, reaction and interaction of energy. New York, NY: Charles Scribner's Sons.
138. Ownby, K., Xu, H. & White, R. H. 2005 A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4- carboxamide-1-β-D-ribofuranosyl 5′-monophosphate synthetase: a new enzyme in purine biosynthesis. J. Biol. Chem. 280, 10 881-10 887. (doi:10.1074/jbc.M413937200)
139. Ozawa, K., Nemoto, A., Imai, E. I., Honda, H., Hatori, K. & Matsuno, K. 2004 Phosphorylation of nucleotide molecules in hydrothermal environments. Orig. Life Evol. Biosph. 34, 465-471. (doi:10.1023/B:ORIG. 0000043121.65714.05)
140. Palandri, J. L. & Reed, M. H. 2004 Geochemical models of metasomatism in ultramafic systems: serpentinization, rodingitization, and sea floor carbonate chimney precipitation. Geochim. Cosmochim. Acta 68, 1115-1133. (doi:10.1016/j.gca.2003.08.006)
141. Penny, D. 2005 An interpretative review of the origin of life research. Biol. Philos. 20, 633-671. (doi:10.1007/s10539-004-7342-6)
142. Pereto, J., Lopez-Garcia, P. & Moreira, D. 2004 Ancestral lipid biosynthesis and early membrane evolution. Trends Biochem. Sci. 29, 469-477.
143. Pitsch, S., Eschenmoser, A., Gedulin, B., Hui, S. & Arrhenius, G. 1995 Mineral induced formation of sugar phosphates. Orig. Life Evol. Biosph. 25, 297-334. (doi:10.1007/BF01581773)
144. Pizzarello, S. & Weber, A. L. 2004 Prebiotic amino acids as asymmetric catalysts. Science 303, 1151.
145. Pohl, M., Sprenger, G. A. & Müller, M. 2004 A new perspective on thiamine catalysis. Curr. Opin. Biotechnol. 15, 335-342. (doi:10.1016/j.copbio.2004.06.002)
146. Poole, A. M. & Logan, D. T. 2005 Modern mRNA proofreading and repair: clues that the Last Universal Common Ancestor (LUCA) possessed an RNA genome? Mol. Biol. Evol. 22, 1444-1455. (doi:10.1093/molbev/msi132)
147. Povich, M. S., Raymond, J. C., Jones, G. H., Uzzo, M., Ko, Y.-K., Feldman, P. D., Smith, P. L., Marsden, B. G. & Woods, T. N. 2003 Doubly ionized carbon observed in the plasma tail of comet Kudo-Fujikawa. Science 302, 1949-1952. (doi:10.1126/science.1092142)
148. Proskurowski, G., Lilley, M. D., Kelley, D. S. & Olson, E. J. 2006 Low temperature volatile production at the Lost City Hydrothermal Field, evidence from a hydrogen stable isotope geothermometer. Chem. Geol. 229, 331-343. (doi:10.1016/j.chemgeo.2005.11.005)
149. Ragsdale, S. W. 2004 Life with carbon monoxide. Crit. Rev. Biochem. Mol. Biol. 39, 165-195. (doi:10.1080/10409230490496577)
150. Rebelo, J. et al. 2003 Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I. J. Mol. Biol. 326, 503-516. (doi:10.1016/S0022-2836(02)01303-7)
151. Ren, Y. 1999 Is carbonyl sulfide a precursor for carbon disulfide in vegetation and soil? Interconversion of carbonyl sulfide and carbon disulfide in fresh grain tissues in vitro. J. Agri. Food Chem. 47, 2141-2144. (doi:10.1021/jf980838u)
152. Rhodes, C., Riddel, S. A., West, J., Williams, B. P. & Hutchings, G. J. 2000 The low-temperature hydrolysis of carbonyl sulfide and carbon disulfide: a review. Catalysis Today 59, 443-464. (doi:10.1016/S0920- 5861(00)00309-6)
153. Ricardo, A., Carrigan, M. A., Olcott, A. N. & Benner, S. A. 2004 Borate minerals stabilize ribose. Science 303, 196. (doi:10.1126/science.1092464)
154. Rivera, M. C. & Lake, J. A. 2004 The ring of life provides evidence for a genome fusion origin of eukaryotes. Nature 431, 152-155. (doi:10.1038/nature02848)
155. Rodionov, D. A., Vitreschak, A. G., Mironov, A. A. & Gelfand, M. S. 2002 Comparative genomics of thiamine biosynthesis in prokaryotes. New genes and regulatory mechanisms. J. Biol. Chem. 277, 48 949-18 959. (doi:10.1074/jbc.M208965200)
156. Rother, M. & Metcalf, W. W. 2004 Anaerobic growth of Methanosarcina acetivorans C2A on carbon monoxide: an unusual way of life for a methanogenic archaeon. Proc. Natl Acad. Sci. USA 101, 16 929-16 934. (doi:10.1073/pnas.0407486101)
157. Russell, M. J. & Arndt, N. T. 2005 Geodynamic and metabolic cycles in the Hadean. Biogeosciences 2, 97-111.
158. Russell, M. J. & Hall, A. J. 1997 The emergence of life from iron monosulphide bubbles at a submarine hydrothermal redox and pH front. J. Geol. Soc. Lond. 154, 377-402.
159. Russell, M. J. & Hall, A. J. 2006 The onset and early evolution of life. In Evolution of early Earth's atmosphere, hydrosphere and biosphere - constraints from ore deposits (eds S. E. Kesler & H. Ohmoto). Memoir 198, pp. 1-32. Boulder, CO: Geological Society of America.
160. Russell, M. J. & Martin, W. 2004 The rocky roots of the acetyl-CoA pathway. Trends Biochem. Sci. 29, 358-363. (doi:10.1016/j.tibs. 2004.05.007)
161. Russell, M. J., Daniel, R. M., Hall, A. J. & Sherringham, J. 1994 A hydrothermally precipitated catalytic iron sulphide membrane as a first step toward life. J. Mol. Evol. 39, 231-243. (doi:10.1007/BF00160147)
162. 2-: functional model for the tungsten-formate dehydrogenase of Clostridium thermoaceticum. Proc. Indian Acad. Sci. (Chemical Science) 104, 533-534.
163. Sapra, R., Bagramyan, K. & Adams, M. W. 2003 A simple energy-conserving system: proton reduction coupled to proton translocation. Proc. Natl Acad. Sci. USA 100, 7545-7550. (doi:10.1073/pnas. 1331436100)
164. Sauer, U. & Eikmanns, B. J. 2005 The PEP-pyruvate-oxalate node as the switch point for carbon flux distribution in bacteria. FEMS Microbiol. Rev. 29, 765-794. (doi:10.1016/j.femsre.2004.11.002)
165. Schäfer, G., Engelhard, M. & Müller, V. 1999 Bioenergetics of the Archaea. Microbiol. Mol. Biol. Rev. 63, 570-620.
166. Schink, B. 1990 Conservation of small amounts of energy in fermenting bacteria. In Biotechnology focus (eds R. K. Finn & P. Präve), pp. 63-89. Munich, Germany: Hanser.
167. Schink, B. 1997 Energetics of syntrophic cooperation in methanogenic degradation. Microbiol. Mol. Biol. Rev. 61, 262-280.
168. Schmitz, R. A., Albracht, S. P. & Thauer, R. K. 1992 A molybdenum and a tungsten isoenzyme of formyl-methanofuran dehydrogenase in the thermophilic archaeon Methanobacterium wolfei. Eur. J. Biochem. 209, 1013-1018. (doi:10.1111/j.1432-1033.1992.tb17376.x)
169. Schönheit, P. & Schäfer, T. 1995 Metabolism of hyperthermophiles. World J. Microbiol. Biotechnol. 11, 26-57. (doi:10.1007/BF00339135)
170. 2 redox couple as reductant. Orig. Life Evol. Biosph. 29, 5-32. (doi:10.1023/A:1006558802113)
171. Schulte, M. D. & Rogers, K. L. 2004 Thiols in hydrothermal solution: Standard partial molar properties and their role in the organic geochemistry of hydrothermal environments. Geochim. Cosmochim. Acta 68, 1087-1097. (doi:10.1016/j.gca.2003.06.001)
172. Schulte, M., Blake, D., Hoehler, T. & McCollom, T. 2006 Serpentinization and its implications for life on the early Earth and Mars. Astrobiology 6, 364-376. (doi:10.1089/ast.2006.6.364)
173. Schütz, M. et al. 2000 Early evolution of cytochrome bc complexes. J. Mol. Biol. 21, 663-675.
174. Schwartz, A. W. 1998 Origins of the RNA world. In The molecular origins of life (ed. A. Brack), pp. 237-254. Cambridge, UK: Cambridge University Press.
175. Seefeldt, L. C., Rasche, M. E. & Ensign, S. A. 1995 Carbonyl sulfide and carbon dioxide as new substrates, and carbon disulfide as a new inhibitor, of nitrogenase. Biochemistry 34, 5382-5389. (doi:10.1021/ bi00016a009)
176. Seefeldt, L. C., Dance, I. G. & Dennis, R. D. 2004 Substrate interactions with nitrogenase: Fe versus Mo. Biochemistry 43, 1401-1409. (doi:10.1021/bi036038g)
177. Seewald, J. S., Zolotov, M. Y. & McCollom, T. 2006 Experimental investigation of single carbon compounds under hydrothermal conditions. Geochim. Cosmochim. Acta 70, 446-460. (doi:10.1016/j.gca.2005.09. 002)
178. Serganov, A., Polonskaia, A., Tuan Phan, A., Breaker, R. R. & Patel, D. J. 2006 Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature 441, 1167-1171. (doi:10.1038/nature04740)
179. Shima, S. & Thauer, R. K. 2005 Methyl-coenzyme M reductase and the anaerobic oxidation of methane in methanotrophic Archaea. Curr. Opin. Microbiol. 8, 643-648.
180. Shirakihara, Y. et al. 1997 The crystal structure of the nucleotide-free alpha 3 beta 3 subcomplex of F1-ATPase from the thermophilic Bacillus PS3 is a symmetric trimer. Structure 5, 825-836. (doi:10.1016/S0969-2126(97)00236-0)
181. Shock, E. L. 1990 Geochemical constraints on the origin of organic compounds in hydrothermal systems. Orig. Life Evol. Biosph. 20, 331-367. (doi:10.1007/BF01808115)
182. Shock, E. L. 1992 Chemical environments of submarine hydrothermal systems. Orig. Life Evol. Biosph. 22, 67-107. (doi:10.1007/ BF01808019)
183. Shock, E. L., McCollom, T. & Schulte, M. D. 1998 The emergence of metabolism from within hydrothermal systems. In Thermophiles: the keys to molecular evolution and the origin of life (eds J. Wiegel & M. W. W. Adams), pp. 59-76. London, UK: Taylor and Francis.
184. Siebers, B. & Schönheit, P. 2005 Unusual pathways and enzymes of central carbohydrate metabolism in Archaea. Curr. Opin. Microbiol. 8, 695-705.
185. Simpson, P. G. & Whitman, W. B. 1993 Anabolic pathways in methanogens. In Methanogenesis: ecology, physiology, biochemistry, and genetics (ed. J. G. Ferry), pp. 445-472. New York, NY: Chapman and Hall.
186. 2-rich fluids from serpentenization: geochemical and biotic implications. Proc. Natl Acad. Sci. USA 101, 12 818-12 823. (doi:10.1073/pnas.0405289101)
187. Smith, E. & Morowitz, H. J. 2004 Universality in intermediary metabolism. Proc. Natl Acad. Sci. USA 101, 13 168-13 173. (doi:10.1073/pnas.0404922101)
188. Smithers, G. W., Jahansouz, H., Kofron, J. L., Himes, R. H. & Reed, G. H. 1987 Substrate activity of synthetic formyl phosphate in the reaction catalyzed by formyltetrahydrofolate synthetase. Biochemistry 26, 3943-3948. (doi:10.1021/bi00387a030)
189. 2-evolving enzyme complex from Carboxydothermus hydrogenoformans. Eur. J. Biochem. 269, 5712-5721. (doi:10.1046/j.1432-1033.2002.03282.x)
190. Springsteen, G. & Joyce, G. F. 2004 Selective derivitization and sequestration of ribose from a prebiotic mix. J. Am. Chem. Soc. 126, 9578-9583. (doi:10.1021/ja0483692)
191. Sprinzl, M., Horn, C., Brown, M., Ioudovitch, A. & Steinberg, S. 1998 Compilation of tRNA sequences and sequences of tRNA genes. Nucleic Acids Res. 26, 148-153. (doi:10.1093/nar/26.1.148)
192. Steitz, T. A. 2005 On the structural basis of peptide-bond formation and antibiotic resistance from atomic structures of the large ribosomal subunit. FEBS Lett. 579, 955-958. (doi:10.1016/j.febslet.2004.11.053)
193. Stone, R. L., Zalkin, H. & Dixon, J. E. 1993 Expression, purification, and kinetic characterization of recombinant human adenylosuccinate lyase. J. Biol. Chem. 268, 19 710-19 716.
194. Stryer, L. 1975 Biochemistry, p. 949. San Francisco, CA: Freemann.
195. Summar, M. L. et al. 2003 Characterization of genomic structure and polymorphisms in the human carbamyl phosphate synthetase I gene. Gene 311, 51-57. (doi:10.1016/S0378-1119(03)00528-6)
196. Sutherland, J. D. & Whitfield, J. N. 1997 Prebiotic chemistry: a bioorganic perspective. Tetrahedron 53, 11 493-11 527. (doi:10.1016/S0040-4020(97)00438-9)
197. Svetlitchnyi, V., Dobbeck, H., Meyer-Klaucke, W., Meins, T., Thiele, B., Römer, P., Huber, R. & Meyer, O. 2004 A functional Ni-Ni-[4Fe4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans. Proc. Natl Acad. Sci. USA 101, 446-451. (doi:10.1073/pnas.0304262101)
198. 6 biosynthesis in higher plants. Proc. Natl Acad. Sci. USA 102, 13 687-13 692. (doi:10.1073/pnas.0506228102)
199. Tamura, K. & Schimmel, P. 2004 Chiral-selective amino-acylation of an RNA minihelix. Science 305, 1253. (doi:10.1126/science.1099141)
200. Tard, C. et al. 2005 Synthesis of the H-cluster framework of iron-only hydrogenase. Nature 433, 610-613. (doi:10.1038/ nature03298)
201. Tate, S. S., Leu, F. Y. & Meister, A. 1972 Rat liver glutamine synthetase. Preparation, properties, and mechanism of inhibition by carbamyl phosphate. J. Biol. Chem. 247, 5312-5321.
202. Tersteegen, A. & Hedderich, R. 1999 Methanobacterium thermoautotrophicum encodes two multisubunit membrane-bound [NiFe] hydrogenases. Transcription of the operons and sequence analysis of the deduced proteins. Eur. J. Biochem. 264, 930-943. (doi:10.1046/j.1432-1327. 1999.00692.x)
203. Thauer, R. K. 1998 Biochemistry of methanogenesis: a tribute to Marjory Stephensen. Microbiology (Amsterdam) 144, 2377-2406.
204. Thauer, R. K., Jungermann, K. & Decker, K. 1977 Energy conservation in chemotrophic anaerobic bacteria. Bacteriol. Rev. 41, 100-180.
205. Thauer, R. K., Klein, A. R. & Hartmann, G. C. 1996 Reactions with molecular hydrogen in microorganisms: evidence for a purely organic hydrogenation catalyst. Chem. Rev. 96, 3031-3042. (doi:10.1021/cr9500601)
206. Tiedeman, A. A., Keyhani, J., Kamholz, J., Daum, H. A., Gots, J. S. & Smith, J. M. 1989 Nucleotide sequence analysis of the purEK operon encoding 5′-phosphoribosyl-5-aminoimidazole carboxylase of Escherichia coli K-12. J. Bacteriol. 171, 205-212.
207. Trotta, R. P., Burt, M. E., Haschemeyer, R. H. & Meister, A. 1971 Reversible dissociation of carbamyl phosphate synthetase into a regulated synthesis subunit and a subunit required for glutamine utilization. Proc. Natl Acad. Sci. USA 68, 2599-2603. (doi:10.1073/pnas.68.10.2599)
208. Ueno, Y., Yamada, K., Yoshida, N., Maruyama, S. & Isozaki, Y. 2006 Evidence from fluid inclusions for microbial methanogenesis in the early Archaean era. Nature 440, 516-519. (doi:10.1038/nature04584)
209. Van Poelje, P. D. & Snell, E. E. 1988 Amine cations promote concurrent conversion of prohistidine decarboxylase from Lactobacillus 30a to active enzyme and a modified proenzyme. Proc. Natl Acad. Sci. USA 85, 8449-8453. (doi:10.1073/pnas.85.22.8449)
210. Verhees, C. H., Kengen, S. W., Tuininga, J. E., Schut, G. J., Adams, M. W., De Vos, W. M. & Van Der Oost, J. 2003 The unique features of glycolytic pathways in Archaea. Biochem. J. 375, 231-246. (doi:10.1042/BJ20021472)
211. Volbeda, A. & Fontecilla-Camps, J. C. 2006 Catalytic nickel-iron-sulfur clusters: from minerals to enzymes. In Topics in organometallic chemistry, vol. 17 (ed. G. Simmonneaux), pp. 57-82. Berlin, Germany: Springer.
212. 2' utilized by formylmethanofuran dehydrogenase from methanogenic Archaea. Eur. J. Biochem. 248, 919-924. (doi:10.1111/j.1432-1033. 1997.00919.x)
213. Vorholt, J. A., Vaupel, M. & Thauer, R. K. 1996 A polyferredoxin with eight [4Fe24S] clusters as a subunit of molybdenum formylmethanofuran dehydrogenase from Methanosarcina barkeri. Eur. J. Biochem. 236, 309-317. (doi:10.1111/j.1432-1033.1996.t01-1-00309.x)
214. Wächtershäuser, G. 1990 Evolution of the first metabolic cycles. Proc. Natl Acad. Sci. USA 87, 200-204. (doi:10.1073/pnas.87.1.200)
215. Wächtershäuser, G. 1992 Groundworks for an evolutionary biochemistry - The iron-sulfur world. Prog. Biophys. Mol. Biol. 58, 85-201. (doi:10.1016/0079-6107(92)90022-X)
216. Wächtershäuser, G. 1998 The case for a hyperthermophilic, chemolithoautotrophic origin of life in an iron-sulfur world. In Thermophiles: the keys to molecular evolution and the origin of life (ed. M. W. W. Adams), pp. 47-57. London, UK: Taylor and Francis.
217. Weber, A. L. 1981 Formation of pyrophosphate, tripolyphosphate, and phosphorylimidazole with the thioester, N,S- diacetyl-cysteamine, as the condensing agent. J. Mol. Evol. 18, 24-29. (doi:10.1007/ BF01733208)
218. Weber, A. L. 1982 Formation of pyrophosphate on hydroxyapatite with thioesters as condensing agents. Biosystems 15, 183-189. (doi:10.1016/0303-2647(82) 90002-8)
219. Wedler, F. C. & Horn, B. R. 1976 Catalytic mechanisms of glutamine synthetase enzymes: studies with analogs of possible intermediates and transition states. J. Biol. Chem. 251, 7530-7538.
220. White III, H. B. 1976 Coenzymes as fossils of an earlier metabolic state. J. Mol. Evol. 7, 101-104. (doi:10.1007/BF01732468)
221. Williamson, J. M. & Brown, G. M. 1979 Purification and properties of L-aspartate-alpha-decarboxylase, an enzyme that catalyzes the formation of beta-alanine in Escherichia coli. J. Biol. Chem. 254, 8074-8082.
222. Wold, F. 1971 Enolase. In The enzymes (eds P. D. Boyer). Hydrolysis. Hydration, vol V, pp. 499-538. New York, NY: Academic Pre.s.
223. Wolfe, A. J. 2005 The acetate switch. Microbiol. Mol. Biol. Rev. 69, 12-50. (doi:10.1128/MMBR.69.1.12-50.2005)
224. Wu, M. et al. 2005 Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901. PLoS Genetics 1, 563-574. (doi:10.1371/journal.pgen.0010065)
225. Wuebbens, M. M. & Rajagopalan, K. V. 1995 Investigation of the early steps of molybdopterin biosynthesis in Escherichia coli through use of in vivo labelling studies. J. Biol. Chem. 270, 1082-1087. (doi:10.1074/jbc.270.3.1082)
226. Yamamoto, I., Saiki, T., Liu, S. M. & Ljungdahl, L. G. 1983 Purification and properties of NADP-dependent formate dehydrogenase from Clostridium thermoaceticum, a tungsten-selenium-iron protein. J. Biol. Chem. 258, 1826-1832.
227. Yang, H. & Abeles, R. H. 1987 Purification and properties of Escherichia coli 4′-phosphopantothenoylcysteine decarboxylase: presence of covalently bound pyruvate. Biochemistry 26, 4076-4081. (doi:10.1021/bi00387a050)
228. Zeikus, J. G., Fuchs, G., Kenealy, W. & Thauer, R. K. 1977 Oxidoreductases involved in cell carbon synthesis of Methanobacterium thermoautotrophicum. J. Bacteriol. 132, 604-613.
229. Zinder, S. H. 1994 Syntrophic acetate oxidation and "reversible acetogenesis". In Acetogenesis (ed. H. L. Drake), pp. 386-415. New York, NY: Chapman and Hall.