Prebiotic Amino Acids as Asymmetric Catalysts

Science

Volumn 303, Issue 5661, 2004, Pages 1151-

  Pizzarello, Sandra ^a   Weber, Arthur L ^b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b NASA AMES RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALANINE; ALDEHYDE; AMINO ACID; BUFFER; CARBOHYDRATE; CARBON; DNA; DRUG DERIVATIVE; ERYTHROSE; FORMALDEHYDE; GLYCOALDEHYDE; GLYCOLALDEHYDE; ISOVALINE; PREBIOTIC AGENT; RNA; SCHIFF BASE; TETROSE; THREOSE; TRIETHYLAMMONIUM ACETATE; UNCLASSIFIED DRUG; VALINE; WATER;

AMINO ACID;

ALDOL REACTION; ARTICLE; ASTRONOMY; ASYMMETRIC CATALYSIS; BIOGENESIS; CATALYSIS; CATALYST; CHEMISTRY; CHIRALITY; ENANTIOMER; HYDROGEN BOND; MASS FRAGMENTOGRAPHY; MOLECULAR EVOLUTION; PRIORITY JOURNAL; STEREOCHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ACETALDEHYDE; ALANINE; AMINO ACIDS; BIOGENESIS; CATALYSIS; EVOLUTION, CHEMICAL; FORMALDEHYDE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROGEN BONDING; METEOROIDS; SCHIFF BASES; STEREOISOMERISM; TETROSES; VALINE; WATER;

EID: 1242329428     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1093057     Document Type: Article

References (8)

1. P. J. Thomas et al., Eds., Comets and the Origin and Evolution of Life (Springer-Verlag, New York, 1997).
2. S. Pizzarello, M. Zolensky, K. Turk, Geochim. Cosmochim. Acta 67, 1589 (2003).
3. A. L. Weber, Orig. Life 31, 71 (2001).
4. W. Notz, B. List, J. Am. Chem. Soc. 122, 7386 (2000).
5. J. L. Bada, S. L. Miller, Biosystems 20, 21 (1987).
6. L. E. Orgel, Science 290, 1306 (2000).
7. K.-U. Schöning et al., Science 290, 1347 (2000).
8. We thank C. de Duve and R. Krishnamurthy for discussions that motivated this study. We thank E. Varon for technical assistance and J. Cronin, G. Cooper, and three anonymous referees for comments and suggestions. The authors were supported by grants from the NASA Exobiology Division.