Primordial reductive amination revisited

Tetrahedron Letters

Volumn 44, Issue 8, 2003, Pages 1695-1697

  Huber, Claudia ^a   Wächtershäuser, Günter ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b NONE   (Germany)

Author keywords

Ferrous hydroxide; Ferrous sulfide; Reductive amination

Indexed keywords

2 OXOACID; ALANINE; AMINO ACID; AMMONIA; DIMETHYLAMINE; FERRIC HYDROXIDE; IRON; METHYLAMINE; PHENYLALANINE; PHENYLALANINE DERIVATIVE; SULFIDE; TYROSINE;

AMINATION; AMINO ACID SYNTHESIS; AQUEOUS SOLUTION; ARTICLE; PH; PKA; PRECIPITATION; REDUCTION;

EID: 0037450456     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)02863-0     Document Type: Article

References (8)

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4. 2O for the in situ precipitation of FeS. Subsequently the serum bottles were charged with appropriate amounts of HCl or NaOH for adjusting the pH. The total liquid volume was brought to 10 ml. Thereafter the reaction was carried out for 17 h at 75°C. All chemicals were purchased from Aldrich.
5. 2O/MeOH gradient (0-100% MeOH) and 0.1% phosphoric acid, using a Merck-Hitachi Pump L-7100 and a Merck-Hitachi UV detector L-7400 at the appropriate wavelength (254 nm for aromatic amino acids and 190 nm for aliphatic amino acids). In addition the yields of the amino acids were confirmed by reaction with ortho-phthaldialdehyde and HPLC analysis according to Bober, H. Beckman Report 1986, 12, 3-5.
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