Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function

Journal of Biological Chemistry

Volumn 278, Issue 31, 2003, Pages 28812-28822

  Nørager, Sofie ^a   Arent, Susan ^a   Björnberg, Olof ^a   Ottosen, Mette ^a   Leggio, Leila Lo ^a   Jensen, Kaj Frank ^a   Larsen, Sine ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; DIMERS; MONOMERS; MUTAGENESIS; NUCLEIC ACIDS; OXIDATION; REACTION KINETICS;

NUCLEOTIDES;

ENZYMES;

AMINO ACID; DIHYDROOROTATE DEHYDROGENASE; DIHYDROOROTATE DEHYDROGENASE A; DIMER; MONOMER; OROTIC ACID; PYRIMIDINE NUCLEOTIDE; UNCLASSIFIED DRUG; URIDINE PHOSPHATE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIUM MUTANT; BINDING SITE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; LACTOCOCCUS LACTIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

BINDING SITES; CRYSTALLIZATION; ELECTROCHEMISTRY; HYDROGEN BONDING; KINETICS; LACTOCOCCUS LACTIS; MATHEMATICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS; OROTIC ACID; OXIDATION-REDUCTION; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; SPECTROPHOTOMETRY; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); LACTOCOCCUS; LACTOCOCCUS LACTIS; POSIBACTERIA; STREPTOCOCCUS;

EID: 0043209013     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303767200     Document Type: Article

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