메뉴 건너뛰기




Volumn 380, Issue 7-8, 1999, Pages 961-967

Processing of artificial peptide-DNA-conjugates by the mitochondrial intermediate peptidase (MIP)

Author keywords

Gene therapy; Mitochondria; Mitochondrial processing peptidase; Ornithine transcarbamylase; Site directed mutagenesis; Transformation vector

Indexed keywords

MITOCHONDRIAL DNA; PEPTIDASE; SIGNAL PEPTIDE; SPACER DNA;

EID: 0032878613     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.1999.119     Document Type: Article
Times cited : (26)

References (42)
  • 2
    • 0028866991 scopus 로고
    • Prediction and identification of new natural substrates of the yeast mitochondrial intermediate peptidase
    • Branda, S.S., and Isaya, G. (1995). Prediction and identification of new natural substrates of the yeast mitochondrial intermediate peptidase. J. Biol. Chem. 270, 27366-27373.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27366-27373
    • Branda, S.S.1    Isaya, G.2
  • 3
    • 0031569417 scopus 로고    scopus 로고
    • Cloning, expression, and chromosomal assignment of the human mitochondrial intermediate peptidase gene (MIPEP)
    • Chew, A., Buck, E.A., Peretz, S., Sirugo, G., Rinaldo, P., and Isaya, G. (1997). Cloning, expression, and chromosomal assignment of the human mitochondrial intermediate peptidase gene (MIPEP). Genomics 40, 493-496.
    • (1997) Genomics , vol.40 , pp. 493-496
    • Chew, A.1    Buck, E.A.2    Peretz, S.3    Sirugo, G.4    Rinaldo, P.5    Isaya, G.6
  • 5
    • 0023818519 scopus 로고
    • Structural identity between the NH2-terminal domain of the rat and human ornithine carbamyltransferase "targeting" sequences
    • Cote, C., Poirier, J., Boulet, D., Dionne, G., and Lacroix, M. (1988). Structural identity between the NH2-terminal domain of the rat and human ornithine carbamyltransferase "targeting" sequences. J. Biol. Chem. 263, 5752-5756.
    • (1988) J. Biol. Chem. , vol.263 , pp. 5752-5756
    • Cote, C.1    Poirier, J.2    Boulet, D.3    Dionne, G.4    Lacroix, M.5
  • 6
    • 0028878635 scopus 로고
    • Mitochondrial presequences can induce aggregation of unfolded proteins
    • Endo, T., Mitsui, S., and Roise, D. (1995). Mitochondrial presequences can induce aggregation of unfolded proteins. FEBS Lett. 359, 93-96.
    • (1995) FEBS Lett. , vol.359 , pp. 93-96
    • Endo, T.1    Mitsui, S.2    Roise, D.3
  • 7
    • 0038940770 scopus 로고    scopus 로고
    • C- to N-terminal translocation of preproteins into mitochondria
    • Folsch, H., Gaume, B., Brunner, M., Neupert, W., and Stuart, R.A. (1998). C- to N-terminal translocation of preproteins into mitochondria. EMBO J. 17, 6508-6515.
    • (1998) EMBO J. , vol.17 , pp. 6508-6515
    • Folsch, H.1    Gaume, B.2    Brunner, M.3    Neupert, W.4    Stuart, R.A.5
  • 8
    • 0022353969 scopus 로고
    • A synthetic signal peptide blocks import of precursor proteins destined for the mitochondrial inner membrane or matrix
    • Gillespie, L.L., Argan, C., Taneja, A.T., Hodges, R.S., Freeman, K.B., and Shore, G.C. (1985). A synthetic signal peptide blocks import of precursor proteins destined for the mitochondrial inner membrane or matrix. J. Biol. Chem. 260, 16045-16048.
    • (1985) J. Biol. Chem. , vol.260 , pp. 16045-16048
    • Gillespie, L.L.1    Argan, C.2    Taneja, A.T.3    Hodges, R.S.4    Freeman, K.B.5    Shore, G.C.6
  • 9
    • 0025277370 scopus 로고
    • A synthetic presequence reversibly inhibits protein import into yeast mitochondria
    • Glaser, S.M., and Cumsky, M.G. (1990). A synthetic presequence reversibly inhibits protein import into yeast mitochondria. J. Biol. Chem. 265, 8808-8816.
    • (1990) J. Biol. Chem. , vol.265 , pp. 8808-8816
    • Glaser, S.M.1    Cumsky, M.G.2
  • 10
    • 0025091956 scopus 로고
    • Protein sorting to mitochondria: Evolutionary conservations of folding and assembly
    • Hartl, F.U., and Neupert, W. (1990). Protein sorting to mitochondria: evolutionary conservations of folding and assembly. Science 247, 930-938.
    • (1990) Science , vol.247 , pp. 930-938
    • Hartl, F.U.1    Neupert, W.2
  • 12
    • 0024688488 scopus 로고
    • Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: Leader peptides cleaved by two matrix proteases share a three-amino acid motif
    • Hendrick, J.P., Hodges, P.E., and Rosenberg, L.E. (1989), Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid motif. Proc. Natl. Acad. Sci. USA 86, 4056-4060.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 4056-4060
    • Hendrick, J.P.1    Hodges, P.E.2    Rosenberg, L.E.3
  • 13
    • 0021262303 scopus 로고
    • Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase
    • Horwich, A.L., Fenton, W.A., Williams, K.R., Kalousek, F., Kraus, J.P., Doolittle, R.F., Konigsberg, W., and Rosenberg, L.E. (1984). Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase. Science 224, 1068-1074.
    • (1984) Science , vol.224 , pp. 1068-1074
    • Horwich, A.L.1    Fenton, W.A.2    Williams, K.R.3    Kalousek, F.4    Kraus, J.P.5    Doolittle, R.F.6    Konigsberg, W.7    Rosenberg, L.E.8
  • 14
    • 0022534459 scopus 로고
    • Targeting of pre-ornithine transcarbamylase to mitochondria: Definition of critical regions and residues in the leader peptide
    • Horwich, A.L., Kalousek, F., Fenton, WA, Pollock, R.A., and Rosenberg, L.E. (1986). Targeting of pre-ornithine transcarbamylase to mitochondria: definition of critical regions and residues in the leader peptide. Cell 44, 451-459.
    • (1986) Cell , vol.44 , pp. 451-459
    • Horwich, A.L.1    Kalousek, F.2    Fenton, W.A.3    Pollock, R.A.4    Rosenberg, L.E.5
  • 15
    • 0025821619 scopus 로고
    • Cleavage of precursors by the mitochondrial processing peptidase requires a compatible mature protein or an intermediate octapeptide
    • Isaya, G., Kalousek, F., Fenton, W.A., and Rosenberg, L.E. (1991). Cleavage of precursors by the mitochondrial processing peptidase requires a compatible mature protein or an intermediate octapeptide. J. Cell Biol. 113, 65-76.
    • (1991) J. Cell Biol. , vol.113 , pp. 65-76
    • Isaya, G.1    Kalousek, F.2    Fenton, W.A.3    Rosenberg, L.E.4
  • 16
    • 0026657150 scopus 로고
    • Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase
    • Isaya, G., Kalousek, F., and Rosenberg, L.E. (1992). Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase. J. Biol. Chem. 267, 7904-7910.
    • (1992) J. Biol. Chem. , vol.267 , pp. 7904-7910
    • Isaya, G.1    Kalousek, F.2    Rosenberg, L.E.3
  • 17
    • 0022341385 scopus 로고
    • Effects of synthetic model peptides resembling the extension peptides of mitochondrial enzyme precursors on import of the precursors into mitochondria
    • Ito, A., Ogishima, T., Ou, W., Omura, T., Aoyagi, H., Lee, S., Mihara, H., and Izumiya, N. (1985). Effects of synthetic model peptides resembling the extension peptides of mitochondrial enzyme precursors on import of the precursors into mitochondria. J. Biochem. 98, 1571-1582.
    • (1985) J. Biochem. , vol.98 , pp. 1571-1582
    • Ito, A.1    Ogishima, T.2    Ou, W.3    Omura, T.4    Aoyagi, H.5    Lee, S.6    Mihara, H.7    Izumiya, N.8
  • 18
    • 0026638856 scopus 로고
    • Rat liver mitochondrial intermediate peptidase (MIP): Purification and initial characterization
    • Kalousek, F., Isaya, G., and Rosenberg, L.E. (1992). Rat liver mitochondrial intermediate peptidase (MIP): purification and initial characterization. EMBO J. 11, 2803-2809.
    • (1992) EMBO J. , vol.11 , pp. 2803-2809
    • Kalousek, F.1    Isaya, G.2    Rosenberg, L.E.3
  • 19
    • 0022423127 scopus 로고
    • A cDNA clone for the precursor of rat mitochondrial ornithine transcarbamylase: Comparison of rat and human leader sequences and conservation of catalytic sites
    • Kraus, J.P., Hodges, P.E., Williamson, C.L., Horwich, A.L., Kalousek, F., Williams, K.R., and Rosenberg, L.E. (1985). A cDNA clone for the precursor of rat mitochondrial ornithine transcarbamylase: comparison of rat and human leader sequences and conservation of catalytic sites. Nucleic Acids Res. 13, 943-952.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 943-952
    • Kraus, J.P.1    Hodges, P.E.2    Williamson, C.L.3    Horwich, A.L.4    Kalousek, F.5    Williams, K.R.6    Rosenberg, L.E.7
  • 20
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 22
    • 0020108755 scopus 로고
    • A mitochondrial protease that cleaves the precursor of ornithine carbamoyltransferase. Purification and properties
    • Miura, S., Mori, M., Amaya, Y., and Tatibana, M. (1982). A mitochondrial protease that cleaves the precursor of ornithine carbamoyltransferase. Purification and properties. Eur. J. Biochem. 122, 641-647.
    • (1982) Eur. J. Biochem. , vol.122 , pp. 641-647
    • Miura, S.1    Mori, M.2    Amaya, Y.3    Tatibana, M.4
  • 24
    • 0024203558 scopus 로고
    • Reconstitution of mitochondrial protein transport with purified ornithine carbamoyltransferase precursor expressed in Escherichia coli
    • Murakami, K., Amaya, Y., Takiguchi, M., Ebina, Y., and Mori, M. (1988). Reconstitution of mitochondrial protein transport with purified ornithine carbamoyltransferase precursor expressed in Escherichia coli. J. Biol. Chem. 263, 18437-18442.
    • (1988) J. Biol. Chem. , vol.263 , pp. 18437-18442
    • Murakami, K.1    Amaya, Y.2    Takiguchi, M.3    Ebina, Y.4    Mori, M.5
  • 25
    • 0030969942 scopus 로고    scopus 로고
    • Protein import into mitochondria
    • Neupert, W. (1997). Protein import into mitochondria. Annu. Rev. Biochem. 66, 863-917.
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 863-917
    • Neupert, W.1
  • 26
    • 0024244832 scopus 로고
    • Role of cytochrome c heme lyase in the import of cytochrome c into mitochondria
    • Nicholson, D.W., Hergersberg, C., and Neupert, W. (1988). Role of cytochrome c heme lyase in the import of cytochrome c into mitochondria. J. Biol. Chem. 263, 19034-19042.
    • (1988) J. Biol. Chem. , vol.263 , pp. 19034-19042
    • Nicholson, D.W.1    Hergersberg, C.2    Neupert, W.3
  • 27
    • 0024468352 scopus 로고
    • Purification and characterization of a processing protease from rat liver mitochondria
    • Ou, W.J., Ito, A., Okazaki, H., and Omura, T. (1989). Purification and characterization of a processing protease from rat liver mitochondria. EMBO J. 8, 2605-2612.
    • (1989) EMBO J. , vol.8 , pp. 2605-2612
    • Ou, W.J.1    Ito, A.2    Okazaki, H.3    Omura, T.4
  • 29
    • 0025360581 scopus 로고
    • The mitochondrial protein import apparatus
    • Pfanner, N., and Neupert, W. (1990). The mitochondrial protein import apparatus. Annu. Rev. Biochem. 59, 331-353.
    • (1990) Annu. Rev. Biochem. , vol.59 , pp. 331-353
    • Pfanner, N.1    Neupert, W.2
  • 30
    • 0023920458 scopus 로고
    • Mitochondrial presequences
    • Roise, D., and Schatz, G. (1988). Mitochondrial presequences. J. Biol. Chem. 263, 4509-4511.
    • (1988) J. Biol. Chem. , vol.263 , pp. 4509-4511
    • Roise, D.1    Schatz, G.2
  • 31
    • 0022725788 scopus 로고
    • A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers
    • Roise, D., Horvath, S.J., Tomich, J.M., Richards, J.H., and Schatz, G. (1986). A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers. EMBO J. 5, 1327-1334.
    • (1986) EMBO J. , vol.5 , pp. 1327-1334
    • Roise, D.1    Horvath, S.J.2    Tomich, J.M.3    Richards, J.H.4    Schatz, G.5
  • 33
    • 0023472472 scopus 로고
    • Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
    • Schägger, H., and von Jagow, G. (1987). Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166, 368-379.
    • (1987) Anal. Biochem. , vol.166 , pp. 368-379
    • Schägger, H.1    Von Jagow, G.2
  • 34
    • 0029774146 scopus 로고    scopus 로고
    • The protein import system of mitochondria
    • Schatz, G. (1996). The protein import system of mitochondria. J. Biol. Chem. 271, 31763-31766.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31763-31766
    • Schatz, G.1
  • 35
    • 0025312373 scopus 로고
    • Matrix processing peptidase of mitochondria. Structure-function relationships
    • Schneider, H., Arretz, M., Wachter, E., and Neupert, W. (1990). Matrix processing peptidase of mitochondria. Structure-function relationships. J. Biol. Chem. 265, 9881-9887.
    • (1990) J. Biol. Chem. , vol.265 , pp. 9881-9887
    • Schneider, H.1    Arretz, M.2    Wachter, E.3    Neupert, W.4
  • 36
    • 0344242830 scopus 로고
    • Replikatives und transkriptionsaktives Peptid-Nukleinsäureplasmid, sowie seine Verwendung zur Einbringung in Zellen und Zellorganellen. German Patent, P 44 21 079
    • Seibel, P., and Seibel, A. (1995). Replikatives und transkriptionsaktives Peptid-Nukleinsäureplasmid, sowie seine Verwendung zur Einbringung in Zellen und Zellorganellen. German Patent, P 44 21 079.
    • (1995)
    • Seibel, P.1    Seibel, A.2
  • 37
    • 0028804570 scopus 로고
    • Transfection of mitochondria: Strategy towards a gene therapy of mitochondrial DNA diseases
    • Seibel, P., Trappe, J., Villani, G., Klopstock, T., Papa, S., and Reichmann, H. (1995). Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases. Nucleic Acids Res. 23, 10-17.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 10-17
    • Seibel, P.1    Trappe, J.2    Villani, G.3    Klopstock, T.4    Papa, S.5    Reichmann, H.6
  • 38
    • 0023571665 scopus 로고
    • Import of rat ornithine transcarbamylase precursor into mitochondria: Two-step processing of the leader peptide
    • Sztul, E.S., Hendrick, J.P., Kraus, J.P., Wall, D., Kalousek, F., and Rosenberg, L.E. (1987). Import of rat ornithine transcarbamylase precursor into mitochondria: two-step processing of the leader peptide. J. Cell Biol. 105, 2631-2639.
    • (1987) J. Cell Biol. , vol.105 , pp. 2631-2639
    • Sztul, E.S.1    Hendrick, J.P.2    Kraus, J.P.3    Wall, D.4    Kalousek, F.5    Rosenberg, L.E.6
  • 39
    • 0039907972 scopus 로고
    • Molecular cloning and nucleotide sequence of cDNA for rat ornithine carbamoyltransferase precursor
    • Takiguchi, M., Miura, S., Mori, M., Tatibana, M., Nagata, S., and Kaziro, Y. (1984). Molecular cloning and nucleotide sequence of cDNA for rat ornithine carbamoyltransferase precursor. Proc. Natl. Acad. Sci. USA 81, 7412-7416.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 7412-7416
    • Takiguchi, M.1    Miura, S.2    Mori, M.3    Tatibana, M.4    Nagata, S.5    Kaziro, Y.6
  • 40
    • 0024536726 scopus 로고
    • DNA-protein conjugates can enter mitochondria via the protein import pathway
    • Vestweber, D., and Schatz, G. (1989). DNA-protein conjugates can enter mitochondria via the protein import pathway. Nature 338, 170-172.
    • (1989) Nature , vol.338 , pp. 170-172
    • Vestweber, D.1    Schatz, G.2
  • 41
    • 0022731676 scopus 로고
    • Mitochondrial targeting sequences may form amphiphilic helices
    • von Heijne, G. (1986). Mitochondrial targeting sequences may form amphiphilic helices. EMBO J. 5, 1335-1342.
    • (1986) EMBO J. , vol.5 , pp. 1335-1342
    • Von Heijne, G.1
  • 42
    • 0024254118 scopus 로고
    • Import of proteins into yeast mitochondria: The purified matrix processing protease contains two subunits which are encoded by the nuclear MAS1 and MAS2 genes
    • Yang, M., Jensen, R.E., Yaffe, M.P., Oppliger, W., and Schatz, G. (1988). Import of proteins into yeast mitochondria: the purified matrix processing protease contains two subunits which are encoded by the nuclear MAS1 and MAS2 genes. EMBO J. 7, 3857-3862.
    • (1988) EMBO J. , vol.7 , pp. 3857-3862
    • Yang, M.1    Jensen, R.E.2    Yaffe, M.P.3    Oppliger, W.4    Schatz, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.