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Volumn 6, Issue 12, 2005, Pages 1176-1181

Phosphorothioate-stimulated uptake of short interfering RNA by human cells

Author keywords

Caveolin; Cellular uptake; Nonviral vector; siRNA, delivery; siRNA, transport

Indexed keywords

CAVEOLIN; LAMIN A; LAMIN C; MESSENGER RNA; OLIGONUCLEOTIDE; PHOSPHOROTHIOIC ACID; SMALL INTERFERING RNA;

EID: 28544444484     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7400535     Document Type: Article
Times cited : (56)

References (27)
  • 1
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: Entering the mainstream
    • Allen TM, Cullis PR (2004) Drug delivery systems: Entering the mainstream. Science 303: 1818-1822
    • (2004) Science , vol.303 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 3
    • 0028956615 scopus 로고
    • Binding uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides
    • Beltinger C et al (1995) Binding uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides. J Clin Invest 95: 1814-1823
    • (1995) J. Clin. Invest. , vol.95 , pp. 1814-1823
    • Beltinger, C.1
  • 4
    • 0034651955 scopus 로고    scopus 로고
    • Identification, purification and partial characterisation of an oligonucleotide receptor in membranes of HepG2 cells
    • de Diesbach P et al (2000) Identification, purification and partial characterisation of an oligonucleotide receptor in membranes of HepG2 cells. Nucleic Acids Res 28: 868-874
    • (2000) Nucleic Acids Res. , vol.28 , pp. 868-874
    • de Diesbach, P.1
  • 5
    • 3242677639 scopus 로고    scopus 로고
    • siRNAs: Applications in functional genomics and potential as therapeutics
    • Dorsett Y, Tuschl T (2004) siRNAs: Applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov 3: 318-329
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 318-329
    • Dorsett, Y.1    Tuschl, T.2
  • 6
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM et al (2001a) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1
  • 7
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir SM, Lendeckel W, Tuschl T (2001b) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 15: 188-200
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 8
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir SM, Harborth J, Weber K, Tuschl T (2002) Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26: 199-213
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 9
    • 0029086362 scopus 로고
    • De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin
    • Fra AM, Williamson E, Simons K, Parton RG (1995) De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin. Proc Natl Acad Sci USA 92: 8655-8659
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8655-8659
    • Fra, A.M.1    Williamson, E.2    Simons, K.3    Parton, R.G.4
  • 10
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon GJ, Rossi JJ (2004) Unlocking the potential of the human genome with RNA interference. Nature 431: 371-378
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 11
    • 0034650517 scopus 로고    scopus 로고
    • Mechanism and function of a newly identified CpG DNA motif in human primary B cells
    • Hartmann G, Krieg AM (2000) Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J Immunol 164: 944-952
    • (2000) J. Immunol. , vol.164 , pp. 944-952
    • Hartmann, G.1    Krieg, A.M.2
  • 12
    • 3142514670 scopus 로고    scopus 로고
    • Progress in the development of nucleic acid therapeutics for cancer
    • Kalota A, Shetzline SE, Gewirtz AM (2004) Progress in the development of nucleic acid therapeutics for cancer. Cancer Biol Ther 3: 4-12
    • (2004) Cancer Biol. Ther. , vol.3 , pp. 4-12
    • Kalota, A.1    Shetzline, S.E.2    Gewirtz, A.M.3
  • 13
    • 0042161890 scopus 로고    scopus 로고
    • The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides
    • Kretschmer-Kazemi Far R, Sczakiel G (2003) The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides. Nucleic Acids Res 31: 4417-4424
    • (2003) Nucleic Acids Res. , vol.31 , pp. 4417-4424
    • Kretschmer-Kazemi Far, R.1    Sczakiel, G.2
  • 14
    • 0035112910 scopus 로고    scopus 로고
    • Enhancing vaccines with immune stimulatory CpG DNA
    • Krieg AM, Davis HL (2001) Enhancing vaccines with immune stimulatory CpG DNA. Curr Opin Mol Ther 3: 15-24
    • (2001) Curr. Opin. Mol. Ther. , vol.3 , pp. 15-24
    • Krieg, A.M.1    Davis, H.L.2
  • 15
    • 0033153374 scopus 로고    scopus 로고
    • Characterisation of membrane oligonucleotide-binding proteins and oligonucleotide uptake in keratinocytes
    • Laktionov PP et al (1999) Characterisation of membrane oligonucleotide-binding proteins and oligonucleotide uptake in keratinocytes. Nucleic Acids Res 27: 2315-2324
    • (1999) Nucleic Acids Res. , vol.27 , pp. 2315-2324
    • Laktionov, P.P.1
  • 16
    • 3242703880 scopus 로고    scopus 로고
    • Cell-surface-bound nucleic acids: Free and cell-surface-bound nucleic acids in blood of healthy donors and breast cancer patients
    • Laktionov PP et al (2004) Cell-surface-bound nucleic acids: Free and cell-surface-bound nucleic acids in blood of healthy donors and breast cancer patients. Ann NY Acad Sci 1022: 221-227
    • (2004) Ann. NY Acad. Sci. , vol.1022 , pp. 221-227
    • Laktionov, P.P.1
  • 17
    • 15444374064 scopus 로고    scopus 로고
    • Spontaneous uptake of biologically active recombinant DNA by mammalian cells via a selected double-stranded DNA segment
    • Lehmann M, Sczakiel G (2005) Spontaneous uptake of biologically active recombinant DNA by mammalian cells via a selected double-stranded DNA segment. Gene Ther 12: 446-451
    • (2005) Gene Ther. , vol.12 , pp. 446-451
    • Lehmann, M.1    Sczakiel, G.2
  • 18
    • 1342302829 scopus 로고    scopus 로고
    • Transfection of 'naked' siRNA results in endosomal uptake and metabolic impairment in cultured neurons
    • Lingor P, Michel U, Schöll U, Bähr M, Kügler S (2004) Transfection of 'naked' siRNA results in endosomal uptake and metabolic impairment in cultured neurons. Biochem Biophys Res Comm 315: 1126-1133
    • (2004) Biochem. Biophys. Res. Comm. , vol.315 , pp. 1126-1133
    • Lingor, P.1    Michel, U.2    Schöll, U.3    Bähr, M.4    Kügler, S.5
  • 19
    • 0016835245 scopus 로고
    • Establishment and characterization of an Epstein-Barr virus (EBV)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-negative African Burkitt's lymphoma
    • Menezes J, Leibold W, Klein G, Clements G (1975) Establishment and characterization of an Epstein-Barr virus (EBV)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-negative African Burkitt's lymphoma. Biomedicine 22: 276-284
    • (1975) Biomedicine , vol.22 , pp. 276-284
    • Menezes, J.1    Leibold, W.2    Klein, G.3    Clements, G.4
  • 20
    • 16544368691 scopus 로고    scopus 로고
    • Quantitative detection of siRNA and single-stranded oligonucleotides: Relationship between uptake and biological activity of siRNA
    • Overhoff M, Wünsche W, Sczakiel G (2004) Quantitative detection of siRNA and single-stranded oligonucleotides: Relationship between uptake and biological activity of siRNA. Nucleic Acids Res 32: E170
    • (2004) Nucleic Acids Res. , vol.32
    • Overhoff, M.1    Wünsche, W.2    Sczakiel, G.3
  • 21
    • 0242268532 scopus 로고    scopus 로고
    • Lipid rafts and caveolae as portals for endocytosis: New insight and common mechanisms
    • Parton RG, Richards AA (2003) Lipid rafts and caveolae as portals for endocytosis: New insight and common mechanisms. Traffic 4: 724-738
    • (2003) Traffic , vol.4 , pp. 724-738
    • Parton, R.G.1    Richards, A.A.2
  • 22
    • 4544375506 scopus 로고    scopus 로고
    • Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic
    • Pelkmans L, Burli T, Zerial M, Helenius A (2004) Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic. Cell 118: 767-780
    • (2004) Cell , vol.118 , pp. 767-780
    • Pelkmans, L.1    Burli, T.2    Zerial, M.3    Helenius, A.4
  • 24
    • 28544433584 scopus 로고
    • Characterization of EBV-genome negative 'null' and 'T' cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma
    • Schneider U, Schwenk HU, Bornkamm G (1977) Characterization of EBV-genome negative 'null' and 'T' cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma. Int J Cancer 22: 204-213
    • (1977) Int. J. Cancer , vol.22 , pp. 204-213
    • Schneider, U.1    Schwenk, H.U.2    Bornkamm, G.3
  • 25
    • 9144247189 scopus 로고    scopus 로고
    • Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
    • Soutschek J et al (2004) Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432: 173-178
    • (2004) Nature , vol.432 , pp. 173-178
    • Soutschek, J.1
  • 26
    • 2542488265 scopus 로고    scopus 로고
    • Regulating eukaryotic gene expression with aptamers
    • Toulmé JJ, Di Primo C, Boucard D (2004) Regulating eukaryotic gene expression with aptamers. FEBS Lett 567: 55-62
    • (2004) FEBS Lett. , vol.567 , pp. 55-62
    • Toulmé, J.J.1    Di Primo, C.2    Boucard, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.